• Title/Summary/Keyword: Chiral β-hydroxy sulfides

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A Convenient Synthesis of Optically Active Unhindered Aliphatic Alcohols with High Optical Purity from Non-Racemic β-Hydroxy Sulfides

  • Cho, Byung-Tae;Kim, Dong-Jun
    • Bulletin of the Korean Chemical Society
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    • v.25 no.9
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    • pp.1385-1391
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    • 2004
  • A general route for the synthesis of optically active unhindered aliphatic alcohols, where the steric demands between two alkyl groups adjacent to the carbinol are similar, with high enantiomeric purity has been developed by sulfoxifation of chiral ${\beta}$-hydroxy sulfides, followed by alkylation and desulfurization.