• Title/Summary/Keyword: Chips

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Detection of Sequence-Specific Gene by Multi-Channel Electrochemical DNA Chips

  • Zhang, Xuzhi;Ji, Xinming;Cui, Zhengguo;Yang, Bing;Huang, Jie
    • Bulletin of the Korean Chemical Society
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    • v.33 no.1
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    • pp.69-75
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    • 2012
  • Five-channel electrochemical chips were fabricated based on the Micro-electromechanical System (MEMS) technology and were used as platforms to develop DNA arrays. Different kinds of thiolated DNA strands, whose sequences were related to white spot syndrome virus (WSSV) gene, were separately immobilized onto different working electrodes to fabricate a combinatorial biosensor system. As a result, different kinds of target DNA could be analyzed on one chip via a simultaneous recognition process using potassium ferricyanide as an indicator. To perform quantitative target DNA detection, a limit of 70 nM (S/N=3) was found in the presence of 600 nM coexisting noncomplementary ssDNA. The real samples of loop-mediated isothermal amplification (LAMP) products were detected by the proposed method with satisfactory result, suggesting that the multichannel chips had the potential for a high effective microdevice to recognize specific gene sequence for pointof-care applications.

Effect of Steam Explosion Condition on the Improvement of Physicochemical Properties of Pine Chips for Feed Additives

  • JUNG, Ji Young;HA, Si Young;YANG, Jae-Kyung
    • Journal of the Korean Wood Science and Technology
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    • v.50 no.1
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    • pp.59-67
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    • 2022
  • Dietary fiber is considered a feed ingredient with high nutritional value in the broiler feed industry. Pine chips contain a large amount of dietary fiber and require some modification for use as broiler feed. In this study, pine chips were subjected to steam explosion under different severity factor (Ro) conditions to improve the chemical and physical properties of dietary fiber. The highest water-holding capacity, oil-holding capacity, and swelling capacity were found for Ro 4.0, followed by Ro4.5 and 3.5. The optimal condition for the steam explosion was determined to be Ro 4.0 (reaction temperature of 210℃, and reaction time of 6.0 min). Under these conditions, the water-holding capacity, oil-holding capacity, and swelling capacity of steam-exploded pine chips were 8.3 g/g, 6.5 g/g, and 5.0 mL/g, respectively. This study may contribute to the application of lignocellulose and related products in the broiler feed industry.

Detection of Defect Patterns on Wafer Bin Map Using Fully Convolutional Data Description (FCDD) (FCDD 기반 웨이퍼 빈 맵 상의 결함패턴 탐지)

  • Seung-Jun Jang;Suk Joo Bae
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.46 no.2
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    • pp.1-12
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    • 2023
  • To make semiconductor chips, a number of complex semiconductor manufacturing processes are required. Semiconductor chips that have undergone complex processes are subjected to EDS(Electrical Die Sorting) tests to check product quality, and a wafer bin map reflecting the information about the normal and defective chips is created. Defective chips found in the wafer bin map form various patterns, which are called defective patterns, and the defective patterns are a very important clue in determining the cause of defects in the process and design of semiconductors. Therefore, it is desired to automatically and quickly detect defective patterns in the field, and various methods have been proposed to detect defective patterns. Existing methods have considered simple, complex, and new defect patterns, but they had the disadvantage of being unable to provide field engineers the evidence of classification results through deep learning. It is necessary to supplement this and provide detailed information on the size, location, and patterns of the defects. In this paper, we propose an anomaly detection framework that can be explained through FCDD(Fully Convolutional Data Description) trained only with normal data to provide field engineers with details such as detection results of abnormal defect patterns, defect size, and location of defect patterns on wafer bin map. The results are analyzed using open dataset, providing prominent results of the proposed anomaly detection framework.

A Study on the Cutting Characteristics of SCM440, SNCM21, STS 304 in Cryogenic Cutting(1st Report) (난삭재의 극저온절삭에서의 절삭 특성에 관한 연구)

  • Kim, Chill-Su;Oh, Sun-Sae;Lim, Young-Ho
    • Journal of the Korean Society for Precision Engineering
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    • v.11 no.1
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    • pp.44-53
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    • 1994
  • We experimented on cutting characteristics-cutting force, behavior of cutting temprature, surface foughness, behavior of chips-under low tempdeature, which generated by liquid nitrogen (77K). The workpieces were freezed to -195 .deg. C and liquid nitrogen was also sprinkled on cutting area in order to increase the efficiency of machining in low temperature. The workpiece was became to -195 .deg. C in 5 minutes, and cutting temperature in CC was lower about 170 .deg. C than NC. The cutting force trended to increase slighty in cooled cutting, but chip thickness was decreased, shear angle was however increased. The form of chips was in good conditions of long or short tubular chips in CC. In CC surface roughness of workpiece was better than NC. In NC surface hardness of chips trended to increase according to increasing of cutting speed, but in CC it trended to decrease. The power spectrum of vertical cutting force trended to increase according to increasing of feed, and in CC it was higher than NC.

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Flavor Compounds in Pine Mushroom Liquor Added with Pine Tree Chips (송절편을 첨가한 송이주의 향기 성분)

  • Yoon, Jeong-Ah;Shin, In-Ung;Park, Eun-Hee;Lee, Ha-Yeon;Kim, Myoung-Dong
    • Microbiology and Biotechnology Letters
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    • v.48 no.3
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    • pp.316-321
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    • 2020
  • Changes in flavor compounds in pine mushroom (Tricholoma matsutake) liquor added with pine tree chips were analyzed using gas chromatography/mass spectrometry. While three flavor compounds were detected in the control, fifteen were detected in the pine mushroom liquor added with pine tree chips. After eight-weeks of aging, the relative concentrations of β-fenchyl alcohol, 2-octanol, and methyl cinnamate, which are distinctive flavor characteristics of the pine mushroom, increased by 67.57%, 2.14%, and 0.94%, respectively, when pine tree chips were added (5%). Principal component analysis revealed that although flavor characteristics of the pine mushroom liquor were affected by the increased production of β-fenchyl alcohol due to the addition of pine tree chips, the aging time exerted a greater influence on flavor.

Automatic Generation of GCP Chips from High Resolution Images using SUSAN Algorithms

  • Um Yong-Jo;Kim Moon-Gyu;Kim Taejung;Cho Seong-Ik
    • Proceedings of the KSRS Conference
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    • 2004.10a
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    • pp.220-223
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    • 2004
  • Automatic image registration is an essential element of remote sensing because remote sensing system generates enormous amount of data, which are multiple observations of the same features at different times and by different sensor. The general process of automatic image registration includes three steps: 1) The extraction of features to be used in the matching process, 2) the feature matching strategy and accurate matching process, 3) the resampling of the data based on the correspondence computed from matched feature. For step 2) and 3), we have developed an algorithms for automated registration of satellite images with RANSAC(Random Sample Consensus) in success. However, for step 1), There still remains human operation to generate GCP Chips, which is time consuming, laborious and expensive process. The main idea of this research is that we are able to automatically generate GCP chips with comer detection algorithms without GPS survey and human interventions if we have systematic corrected satellite image within adaptable positional accuracy. In this research, we use SUSAN(Smallest Univalue Segment Assimilating Nucleus) algorithm in order to detect the comer. SUSAN algorithm is known as the best robust algorithms for comer detection in the field of compute vision. However, there are so many comers in high-resolution images so that we need to reduce the comer points from SUSAN algorithms to overcome redundancy. In experiment, we automatically generate GCP chips from IKONOS images with geo level using SUSAN algorithms. Then we extract reference coordinate from IKONOS images and DEM data and filter the comer points using texture analysis. At last, we apply automatically collected GCP chips by proposed method and the GCP by operator to in-house automatic precision correction algorithms. The compared result will be presented to show the GCP quality.

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Microchips and their Significance in Isolation of Circulating Tumor Cells and Monitoring of Cancers

  • Sahmani, Mehdi;Vatanmakanian, Mousa;Goudarzi, Mehdi;Mobarra, Naser;Azad, Mehdi
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.879-894
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    • 2016
  • In micro-fluid systems, fluids are injected into extremely narrow polymer channels in small amounts such as micro-, nano-, or pico-liter scales. These channels themselves are embedded on tiny chips. Various specialized structures in the chips including pumps, valves, and channels allow the chips to accept different types of fluids to be entered the channel and along with flowing through the channels, exert their effects in the framework of different reactions. The chips are generally crystal, silicon, or elastomer in texture. These highly organized structures are equipped with discharging channels through which products as well as wastes of the reactions are secreted out. A particular advantage regarding the use of fluids in micro-scales over macro-scales lies in the fact that these fluids are much better processed in the chips when they applied as micro-scales. When the laboratory is miniaturized as a microchip and solutions are injected on a micro-scale, this combination makes a specialized construction referred to as "lab-on-chip". Taken together, micro-fluids are among the novel technologies which further than declining the costs; enhancing the test repeatability, sensitivity, accuracy, and speed; are emerged as widespread technology in laboratory diagnosis. They can be utilized for monitoring a wide spectrum of biological disorders including different types of cancers. When these microchips are used for cancer monitoring, circulatory tumor cells play a fundamental role.

Variation in Flexural Fracture Behavior of Silicon Chips before and after Plastic Encapsulation (프라스틱 패키징 전과 후 실리콘 칩들의 휨 파괴 운형에 대한 변화)

  • Lee, Seong-Min
    • Journal of the Microelectronics and Packaging Society
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    • v.15 no.1
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    • pp.65-69
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    • 2008
  • This work shows that the grinding-induced scratches formed on the back surface of silicon chips can highly influence the flexural strength of the chips. Meanwhile, in a case that excellent adhesion between the back surface and the plastic package body maintains, the flexural strength of plastic-encapsulated packages is not so sensitive to the geometry of the scratch marks. This article explains why such different flexural fracture behavior between bare chips and plastic-encapsulated chips appears.

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The Composting Techniques for On-site Recycling of Wood Waste (임목폐기물의 현장 재활용을 위한 퇴비화기술)

  • Hur, Young-Jin;Koh, Jeung-Hyun;Joo, Paik;Ahn, Tae-Young
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.12 no.4
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    • pp.72-80
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    • 2009
  • The main purpose of this study is as follows : Finding a solution for fresh wood chips to be used as an alternative growing-media through a study of the formation method of a compost base that is applicable on both construction site and composting factory to ferment fresh wood chips produced from construction site as well as a study on adjuvant or secondary materials. The result from the experiment plot using wood chips sized 50mm or less, manure and fertilizer mixed manure as a source of nitrogen to compost fresh wood chips has shown that the temperatures 9days and 3days after the beginning of the experiment reached to $49.0^{\circ}C$ and $40.4^{\circ}C$ respectively, the heating duration was 7days and 4days respectively, and the C/N ratio was 26.5 and 25.3, each satisfying the standard for composted manure (25.0~40.0). Also, the other result from another experiment plot using mixture of sandy soil and microorganism as an inoculation source of microorganism has shown that the temperature 10days after the beginning of the experiment reached to $67.6^{\circ}C$ and lasted 16days. The experiment plot using sandy soil has shown the highest figure of $5.3{\sim}108$ CFU/g in terms of number of microorganism. The result from the experiment plots for on-site composting of fresh wood chips have shown that the experiment plot that used sandy soil with fertilizer due to supply restriction of manure as a nitrogen source in construction site reached the high temperature of $54.7^{\circ}C$ after 3days of experiment beginning and maintained heating state for 17days and reached 30.6 of C/N ratio, satisfying the standard for composted manure.

Biodegradation and Saccharification of Wood Chips of Pinus strobus and Liriodendron tulipifera by White Rot Fungi

  • Hwang, Soon-Seok;Lee, Sung-Jae;Kim, Hee-Kyu;Ka, Jong-Ok;Kim, Kyu-Joong;Song, Hong-Gyu
    • Journal of Microbiology and Biotechnology
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    • v.18 no.11
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    • pp.1819-1825
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    • 2008
  • Degradation and glucose production from wood chips of white pine (Pinus strobus) and tulip tree (Liriodendron tulipifera) by several white rot fungi were investigated. The highest weight losses from 4 g of wood chips of P. strobus and L. tulipifera by the fungal degradation on yeast extract-malt extract-glucose agar medium were 38% of Irpex lacteus and 93.7% of Trametes versicolor MrP 1 after 90 days, respectively. When 4 g of wood chips of P. strobus and L. tulipifera biodegraded for 30 days were treated with cellulase, glucose was recovered at the highest values of 106 mg/g degraded wood by I. lacteus and 450 mg/g degraded wood by T. versicolor. The weight loss of 10 g of wood chip of L. tulipifera by T. versicolor on the nutrient non-added agar under the nonsterile conditions was 35% during 7 weeks of incubation, and the cumulative amount of glucose produced during this period was 239 mg without cellulase treatment. The activities of ligninolytic enzymes (lignin peroxidase, manganese peroxidase, and laccase) of fungi tested did not show a high correlation with degradation of the wood chips and subsequent glucose formation. These results suggest that the selection of proper wood species and fungal strain and optimization of glucose recovery are all necessary for the fungal pretreatment of woody biomass as a carbon substrate.