• Journal of Family Relations
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• v.23 no.1
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• pp.121-137
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• 2018

Objectives: This study examined the effects of perceived equity in decision-making and gender role attitudes on marital satisfaction among Chinese-Han and Korean-Chinese migrant women. Methods: Data were drawn from the 'National Survey on the Multi-Cultural Families in 2015' and 1,350 Chinese migrant women born after 1979 under the implementation of "one child policy" were selected. Chi-squared test, t-test, and multiple regression analysis were performed for analysis. Results: There were differences between Chinese-Han and Korean-Chinese in marital satisfaction and perceived equity in decision-making. For Chinese-Han, 'balanced group (perceived fairness in decision-making)' showed higher marital satisfaction than 'underbenefited group (husband is more dominant in decision-making)'. For Korean-Chinese, there was no significant difference between the groups. Conclusions: This study found how the perception of equity in decision-making would affect the quality of international marriage relationship. Especially, for Chinese-Han women, the equity plays an important role in marriage relationship.

• Journal of Ginseng Research
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• v.45 no.1
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• pp.1-21
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• 2021

Panax species have gained numerous attentions because of their various biological effects on cardiovascular, kidney, reproductive diseases known for a long time. Recently, advanced analytical methods including thin layer chromatography, high-performance thin layer chromatography, gas chromatography, high-performance liquid chromatography, ultra-high performance liquid chromatography with tandem ultraviolet, diode array detector, evaporative light scattering detector, and mass detector, two-dimensional high-performance liquid chromatography, high speed counter-current chromatography, high speed centrifugal partition chromatography, micellar electrokinetic chromatography, high-performance anion-exchange chromatography, ambient ionization mass spectrometry, molecularly imprinted polymer, enzyme immunoassay, 1H-NMR, and infrared spectroscopy have been used to identify and evaluate chemical constituents in Panax species. Moreover, Soxhlet extraction, heat reflux extraction, ultrasonic extraction, solid phase extraction, microwave-assisted extraction, pressurized liquid extraction, enzyme-assisted extraction, acceleration solvent extraction, matrix solid phase dispersion extraction, and pulsed electric field are discussed. In this review, a total of 219 articles published from 1980 to 2018 are investigated. Panax species including P. notoginseng, P. quinquefolius, sand P. ginseng in the raw and processed forms from different parts, geographical origins, and growing times are studied. Furthermore, the potential biomarkers are screened through the previous articles. It is expected that the review can provide a fundamental for further studies.

• Journal of Ginseng Research
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• v.46 no.4
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• pp.561-571
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• 2022

Background: Ginsenoside Rb1 (GRb1) is capable of regulating lipid and glucose metabolism through its action on adipocytes. However, the beneficial role of GRb1-induced up-regulation of adiponectin in liver steatosis remains unelucidated. Thus, we tested whether GRb1 ameliorates liver steatosis and insulin resistance by promoting the expression of adiponectin. Methods: 3T3-L1 adipocytes and hepatocytes were used to investigate GRb1's action on adiponectin expression and triglyceride (TG) accumulation. Wild type (WT) mice and adiponectin knockout (KO) mice fed high fat diet were treated with GRb1 for 2 weeks. Hepatic fat accumulation and function as well as insulin sensitivity was measured. The activation of AMPK was also detected in the liver and hepatocytes. Results: GRb1 reversed the reduction of adiponectin secretion in adipocytes. The conditioned medium (CM) from adipocytes treated with GRb1 reduced TG accumulation in hepatocytes, which was partly attenuated by the adiponectin antibody. In the KO mice, the GRb1-induced significant decrease of TG content, ALT and AST was blocked by the deletion of adiponectin. The elevations of GRb1-induced insulin sensitivity indicated by OGTT, ITT and HOMA-IR were also weakened in the KO mice. The CM treatment significantly enhanced the phosphorylation of AMPK in hepatocytes, but not GRb1 treatment. Likewise, the phosphorylation of AMPK in liver of the WT mice was increased by GRb1, but not in the KO mice. Conclusions: The up-regulation of adiponectin by GRb1 contributes to the amelioration of liver steatosis and insulin resistance, which further elucidates a new mechanism underlying the beneficial effects of GRb1 on obesity.

• Journal of Ginseng Research
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• v.48 no.3
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• pp.298-309
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• 2024

Background: 20(S)-ginsenoside Rh2(GRh2), an effective natural histone deacetylase inhibitor, can inhibit acute myeloid leukemia (AML) cell proliferation. Lactate regulated histone lactylation, which has different temporal dynamics from acetylation. However, whether the high level of lactylation modification that we first detected in acute promyelocytic leukemia (APL) is associated with all-trans retinoic acid (ATRA) resistance has not been reported. Furthermore, Whether GRh2 can regulate lactylation modification in ATRA-resistant APL remains unknown. Methods: Lactylation and METTL3 expression levels in ATRA-sensitive and ATRA-resistant APL cells were detected by Western blot analysis, qRT-PCR and CO-IP. Flow cytometry (FCM) and APL xenograft mouse models were used to determine the effect of METTL3 and GRh2 on ATRA-resistance. Results: Histone lactylation and METTL3 expression levels were considerably upregulated in ATRA-resistant APL cells. METTL3 was regulated by histone lactylation and direct lactylation modification. Overexpression of METTL3 promoted ATRA-resistance. GRh2 ameliorated ATRA-resistance by downregulated lactylation level and directly inhibiting METTL3. Conclusions: This study suggests that lactylation-modified METTL3 could provide a promising strategy for ameliorating ATRA-resistance in APL, and GRh2 could act as a potential lactylation-modified METTL3 inhibitor to ameliorate ATRA-resistance in APL.

• Speech Sciences
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• v.14 no.3
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• pp.59-76
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• 2007

The purpose of this study is to investigate the pitch rules of Chinese poetry. Pitch rules are concerned with the high tone and the low tone. Because Chinese poetry is a fixed form of verse, it must keep pitch rules to compose Chinese poetry. But until now there has been no acoustic study of pitch rules of Chinese poetry. So, for the first time the present study investigates pitch rules of Chinese poetry acoustically. Pitch contours were analyzed from the sound spectrogram made by Praat. Results showed that actual pitch patterns did not coincide with theoretical pitch rules in reciting Chinese poetry. Therefore, in studying Chinese classics, the Chinese poetry, which has traditionally been considered to be recited according to original Chinese pitch rules, must now be considered in terms of how pitch rules may have changed over time in Korea since it was first introduce to Korean scholars.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.5
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• pp.371-376
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• 2014

Amino-acid neurotransmitter system dysfunction plays a major role in the pathophysiology of depression. Several studies have demonstrated the potential of amino acids as a source of neuro-specific biomarkers could be used in future diagnosis of depression. Only partial amino acids such as glycine and asparagine were determined from certain parts of rats' brain included hippocampi and cerebral cortex in previous studies. However, according to systematic biology, amino acids in different area of brain are interacted and interrelated. Hence, the determination of 34 amino acids through entire rats' brain was conducted in this study in order to demonstrate more possibilities for biomarkers of depression by discovering other potential amino acids in more areas of rats' brain. As a result, 4 amino acids (L-aspartic acid, L-glutamine, taurine and ${\gamma}$-amino-n-butyric acid) among 34 were typically identified as potentially primary biomarkers of depression by data statistics. Meanwhile, an antidepressant called Fluoxetine was employed to verify other potential amino acids which were not identified by data statistics. Eventually, we found L-${\alpha}$-amino-adipic acid could also become a new potentially secondary biomarker of depression after drug validation. In conclusion, we suggested that L-aspartic acid, L-glutamine, taurine, ${\gamma}$-amino-n-butyric acid and L-${\alpha}$-amino-adipic acid might become potential biomarkers for future diagnosis of depression and development of antidepressant.

• Journal of architectural history
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• v.7 no.4 s.17
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• pp.175-190
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• 1998

The formation of Chinese Town in Malacca of Malaysia and Singapore would explain that Chinese gradually played an important role of commerce and urban service according to the Western European advance to southeast Asia and the construction of colonial cities from the 16th century to 19th and massed residence in many cites of southeast Asia. Chinese was usually separated from the Western European by western colonial policy and city planning. Common architectural characteristics in Chinese towns of Malaysia can refer to the transmission of the Chinese architectural material, the combination of dwelling and commerce in a house and the space organization centered on a court or an air well in the narrow and long site, lying adjacent to street etc. The Chinese dwellings in Malaysia rooted with Chinese settlement in southeast Asia. The Chinese dwellings was not always a shop on 1th floor and a dwelling on 2nd floor before the 19th century. But as Chinese immigration and commercial activity progressed in earnest in the early of 19th century, the row house of Chinese for dwelling was autonomously changed to two functional shophouse for dwelling and commerce. Chinese row house can refer to the use of Malay regional material, change of symmetrical Chinese traditional housing type by the narrow and long site and the tendency of the eclectic elevation of Western and China. Another architectural characteristics of the shophouse is an appearance of the continuous verandah with a cover regulated by Stamford Raffles in Singapore. This regulation was applied to architecture in Chinese Town as Stamford Raffles constructed Singapore. It was spread to South China reversely and became the regulation of streetscape for the modern city. Shophouse of Chinese towns in Southeast Asia and south China can be understood by context of Chinese immigration, colonialism, housing type of commerce and dwelling and the Western European city planning.

• Korean Journal of Health Education and Promotion
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• v.16 no.2
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• pp.41-54
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• 1999

Health behaviors determine people's health status and the Quality of their life. Health education is the most effective method to change people's health behaviors in modem life. Therefore health education for adolescents is essencial to form desirable health behaviors and improve the Quality of their life. This study was administered to analyze important needs for the health education among Chinese, Korean -Chinese adolescents in Gilin, China and Korean adolescents in Seoul. Korea. The data were collected from 387 chinese and 74 Korean-Chinese boys and girls of 3 high schools in Gilin, China and 359 boys and girls of 3 high schools in Seoul, Korea. The results were as follow: 1. Forty percent of Korean students were sick during the past 4 weeks, but only 10.8％ of Korean-Chinese students and 9％ of Chinese students were sick. More than 70％ of Chinese and Korean-Chinese students had health concern, but only 26.6％ of Korean students were interested in health. 2. Korean-Chinese and Chinese students had higher health education needs than the Korean. They were not interested in sex education. On the other hand, Korean students were interested in mental health and not interested in consumer health education. 3. Korean-Chinese students had more health education needs than Chinese or Korean adolescents and the difference was statistically significant (p〈0.05). 4. In Korean-Chinese students, family income and academic grades were significantly related to their health education needs (p〈0.05). Among Chinese students, recent illness was related to their health education needs. In Korean students, the better health status and the more family income. the higher health education needs.

• Korean Journal of Community Nutrition
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• v.18 no.6
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• pp.555-564
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• 2013

The purpose of this study was to compare and analyze the assessment of salty taste and high-salt dietary behaviors of Korean university students and their Chinese counterparts. The researchers developed a taste assessment computer program focusing on preference for salty taste, and it was applied to 300 university students, including 100 Korean students, and 100 Chinese students in Daegu of South Korea, and 100 Chinese students in Shenyang of China (144 males and 156 females). The results of the taste assessment of Chinese and Korean university students are as follows. Among males, Koreans (36.0%), Chinese students in Korea (36.2%), and Chinese (40.4%) scored highest in the "a bit salty" followed by "normal." Among females, Koreans (36.0%), Chinese students in Korea (49.1%), and Chinese (28.3%) scored highest in the "normal". In terms of salt concentration in solution, among the male subjects, most Koreans favored the salt concentration of 0.31%, which is considered to be a "normal" concentration; most Chinese students in Korea favored 0.63%, which is considered to be "a bit salty", and most Chinese favored the concentration of 1.25%, which is considered to be "salty". As for the female subjects, Koreans, Chinese students studying abroad, and Chinese favored 0.31%, the "normal" level of concentration. Korean students scored higher than Chinese students in Korea and Chinese students both in males and females (p < 0.001, p < 0.01), in terms of high-salt dietary behaviors favored salty taste. This study suggests that Chinese university students need nutrition education in terms of modifying eating behaviors to reduce dietary salt intake.

• Journal of the Korean Society of Food Culture
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• v.15 no.5
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• pp.368-378
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• 2000

This study was conducted to assess dietary intake and quality obtained by 24-hour recall method between Korean-Chinese in Yanbian, China(Korean-Chinese) and Koreans in Kuri, Korea(Koreans). The subjects consisted of 730 Korean-Chinese and 696 Koreans. Mean daily energy intake of Korean-Chinese was 1,788kcal and that of Korean was 1,844kcal. Proportions of energy intake from carbohydrate, fat, and protein were 62.6: 16.9: 14.2 for Korean-Chinese and 65.4: 16.3: 14.4 for Koreans. Nutrient intake levels of Koreans were higher than those of Korean-chinese in most nutrients. Calcium and vitamin $B_2$ intakes as percent of Korean RDA were less than 60% in Korean-Chinese. Koreans consumed calcium and vitamin A in the level less than 80% of Korean RDA. Iron intake level of Korean females was less than 75% of Korean RDA. Korean-Chinese consumed 90.4% of food from plant origin, and Koreans consumed 82.5% of food from plant origin. Mean dietary diversity score(DDS) of Korean-Chinese, $3.00{\pm}0.39$, was significantly lower than that of Koreans, $3.73{\pm}0.76(p<0.05)$. Mean dietary variety score(DVS) of Korean-Chinese, 13.6, was significantly lower than that of Koreans, 20.1(p<0.001). According to these results, some adults in the both Korean-Chinese and Koreans did not consume enough nutrients, especially calcium and vitamin $B_2$ intake for Korean-Chinese and calcium and vitamin A intake for Koreans. Dietary qualities of Korean-Chinese subjects and Korean females were not adequate. In the future, further research to promote dietary quality of Koreans including Korean-Chinese must consider the results of this study.