• 예술인문사회 융합 멀티미디어 논문지
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• 제9권9호
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• pp.1-16
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• 2019

본 연구는 국내의 이공계 대학 유학생들의 전공기초 능력 향상 및 중도탈락 예방을 위한 물리교육 프로그램을 개발하기 위하여 수행되었다. 연구의 대상은 한국의 이공계 대학에 재학 중인 중국 유학생 5명으로, 자연과학대학 또는 공과대학에 소속되어 있다. 연구자는 물리교육 프로그램 개발에 앞서 5차시 분량의 대학 기초 물리 교재와 진단 및 총괄 평가 문항을 개발하였으며, 이를 활용하여 총 7차시의 수업을 실시하였다. 수업 적용 후 학습자의 진단 및 총괄 평가 결과, 교수자의 수업일지, 수업참관자 일지, 수업전사본 등을 활용하여 삼각검증 방법으로 분석하였다. 또한 질적인 분석을 돕기 위하여 수업일지와 수업관찰지의 분석에는 Nvivo12가 활용되었다. 연구의 결과는 다음과 같다. 첫째, 이공계 대학의 유학생을 위한 물리교육 프로그램의 순서와 내용을 구체적으로 제시하였고, 대학 기초 물리 교재와 진단 및 총괄 평가 도구를 개발하였다. 둘째, 프로그램의 사전-사후 평가 결과 분석 결과, 개발된 프로그램의 적용에 따라 유학생들의 대학 기초 물리 학업 성취가 평균 40점 향상되었다. 셋째, Nvivo12를 활용한 프로그램의 적용 결과, 의미 있는 노드 생성 및 사례가 추출되었다. 생성된 노드는 총 10종으로, 수업방법, 수업이해도, 수업참여도, 수준차이, 언어문제, 전공과의 관련성, 출신국의 교육과정 및 교육방법, 협력학습, 흥미유발 등이며, 이와 관련된 사례를 토대로 국내 이공계 대학의 유학생들을 위한 물리교육 방법에 관한 시사점을 제공하였다.

• 동의생리병리학회지
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• 제25권5호
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• pp.765-772
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• 2011

Knowledge which is represented by formal logic are widely used in many domains such like artificial intelligence, information retrieval, e-commerce and so on. And for medical field, medical documentary records retrieval, information systems in hospitals, medical data sharing, remote treatment and expert systems need knowledge representation technology. To retrieve information intellectually and provide advanced information services, systematically controlled mechanism is needed to represent and share knowledge. Importantly, medical expert's knowledge should be represented in a form that is understandable to computers and also to humans to be applied to the medical information system supporting decision making. And it should have a suitable and efficient structure for its own purposes including reasoning, extendability of knowledge, management of data, accuracy of expressions, diversity, and so on. we call it ontology which can be processed with machines. We can use the ontology to represent traditional medicine knowledge in structured and systematic way with visualization, then also it can also be used education materials. Hence, the authors developed an Shanghanlun ontology by way of showing an example, so that we suggested a methodology for ontology development and also a model to structure the traditional medical knowledge. And this result can be used for student to learn Shanghanlun by graphical representation of it's knowledge. We analyzed the text of Shanghanlun to construct relational database including it's original text, symptoms and herb formulars. And then we classified the terms following some criterion, confirmed the structure of the ontology to describe semantic relations between the terms, especially we developed the ontology considering visual representation. The ontology developed in this study provides database showing fomulas, herbs, symptoms, the name of diseases and the text written in Shanghanlun. It's easy to retrieve contents by their semantic relations so that it is convenient to search knowledge of Shanghanlun and to learn it. It can display the related concepts by searching terms and provides expanded information with a simple click. It has some limitations such as standardization problems, short coverage of pattern(證), and error in chinese characters input. But we believe this research can be used for basic foundation to make traditional medicine more structural and systematic, to develop application softwares, and also to applied it in Shanghanlun educations.

• The Korean Journal of Physiology and Pharmacology
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• 제12권2호
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• pp.83-87
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• 2008

The fyn-related kinase (FRK) belongs to the tyrosine kinase family of protein kinases. Recent studies have shown that Frk affects pancreatic beta cell number during embryogenesis and promotes beta cell cytotoxic signals in response to streptozotocin. To investigate the genetic association between FRK polymorphisms and the risk of obesity in Korean population, single nucleotide polymorphisms (SNPs) in the FRK gene region were selected and analyzed. The body mass index (BMI) was calculated, and biochemical data (systolic blood pressure, diastolic blood pressure, hemoglobin A1C, triglyceride, total cholesterol, high density lipoprotein, and low density lipoprotein) of blood sample from each subject were also measured. One hundred fifty five healthy control and 204 overweight/obesity subjects were recruited. Genotype frequencies of six SNPs [rs6568920 (+8391G>A), rs3756772 (+56780A>G), rs3798234 (+75687C>T), rs9384970 (+68506G>A), rs1933739 (+72978G>A), and rs9400883 (+75809A>G)] in the FRK gene were determined by Affymetrix Targeted Genotyping Chip data. According to the classification of Korean Society for the Study of Obesity, control (BMI 18 to < 23) and overweight/obesity (BMI$\geq$23) subjects were recruited. For the analysis of genetic data, EM algorithm, SNPStats, Haploview, HapAnalyzer, SNPAnalyzer, and Helixtree programs were used. Multiple logistic regression analysis (codominant, dominant, and recessive models) was performed. Age and gender as covariates were adjusted. For biochemical data, Student's t test was used. The mean value of BMI in the control and overweigh/obesity groups was 21.1${\pm}$1.2 (mean${\pm}$SD) and 25.6${\pm}$2.0, respectively. All biochemical data of the overweight/obesity group were statistically significance, compared with the control group. Among six SNPs, two linkage disequilibrium (LD) blocks were discovered. One block consisted of rs1933739 and rs9400883, and the other comprised rs3756772 and rs3798234. One SNP (rs9384970, +68506G>A) showed an association with overweight/obesity in the codominant model (p=0.03). Interestingly, the AA genotype distribution in the overweight/obesity group (n=7, 3.5%) was higher than those in the control group (n=1, 0.6%), which is not found in either Japanese or Chinese subjects. Therefore, the AA genotype of rs9384970 may be a risk factor for development of obesity in Korean population. The results suggest that FRK may be associated with overweight/obesity in Korean population.