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Imaging Evaluation of Peritoneal Metastasis: Current and Promising Techniques

  • Chen Fu;Bangxing Zhang;Tiankang Guo;Junliang Li
    • Korean Journal of Radiology
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    • v.25 no.1
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    • pp.86-102
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    • 2024
  • Early diagnosis, accurate assessment, and localization of peritoneal metastasis (PM) are essential for the selection of appropriate treatments and surgical guidance. However, available imaging modalities (computed tomography [CT], conventional magnetic resonance imaging [MRI], and 18fluorodeoxyglucose positron emission tomography [PET]/CT) have limitations. The advent of new imaging techniques and novel molecular imaging agents have revealed molecular processes in the tumor microenvironment as an application for the early diagnosis and assessment of PM as well as real-time guided surgical resection, which has changed clinical management. In contrast to clinical imaging, which is purely qualitative and subjective for interpreting macroscopic structures, radiomics and artificial intelligence (AI) capitalize on high-dimensional numerical data from images that may reflect tumor pathophysiology. A predictive model can be used to predict the occurrence, recurrence, and prognosis of PM, thereby avoiding unnecessary exploratory surgeries. This review summarizes the role and status of different imaging techniques, especially new imaging strategies such as spectral photon-counting CT, fibroblast activation protein inhibitor (FAPI) PET/CT, near-infrared fluorescence imaging, and PET/MRI, for early diagnosis, assessment of surgical indications, and recurrence monitoring in patients with PM. The clinical applications, limitations, and solutions for fluorescence imaging, radiomics, and AI are also discussed.

Comparative proteomic analysis of PK-15 cells infected with wild-type strain and its EP0 gene-deleted mutant strain of pseudorabies virus

  • Di Wang;Dongjie Chen;Shengkui Xu;Fang Wei;Hongyuan Zhao
    • Journal of Veterinary Science
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    • v.25 no.4
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    • pp.54.1-54.16
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    • 2024
  • Importance: As one of the main etiologic agents of infectious diseases in pigs, pseudorabies virus (PRV) infections have caused enormous economic losses worldwide. EP0, one of the PRV early proteins (EP) plays a vital role in PRV infections, but the mechanisms are unclear. Objective: This study examined the function of EP0 to provide a direction for its in-depth analysis. Methods: In this study, the EP0-deleted PRV mutant was obtained, and Tandem Mass Tag-based proteomic analysis was used to screen the differentially expressed proteins (DEPs) quantitatively in EP0-deleted PRV- or wild-type PRV-infected porcine kidney 15 cells. Results: This study identified 7,391 DEPs, including 120 and 21 up-regulated and down-regulated DEPs, respectively. Western blot analysis confirmed the changes in the expression of the selected proteins, such as speckled protein 100. Comprehensive analysis revealed 141 DEPs involved in various biological processes and molecular functions, such as transcription regulator activity, biological regulation, and localization. Conclusions and Relevance: These results holistically outlined the functions of EP0 during a PRV infection and might provide a direction for more detailed function studies of EP0 and the stimulation of lytic PRV infections.

A Comparative Study on the Technical Capabilities of General Motors and Hyundai Motor's Joint Venture Research Institutes in China (GM과 현대자동차의 중국 내 합작 연구소의 기술적 능력에 관한 비교 연구)

  • Hwang, Hyunil;Oh, Joongsan
    • Korean Journal of Labor Studies
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    • v.24 no.2
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    • pp.367-408
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    • 2018
  • This study examines the features of globalization process in GM and Hyundai Motors, especially in the expansion into China auto market, through a joint venture(hereafter JV) research center. Due to the large scale market in China and the 50:50 JV, the two companies had to respond in some way to the Chinese government's request for localization of research and development functions, and their response affected the role of the JV research center. Even though the improvement in technological capability expected from the JV by the Chinese side did not appear well in the early stage in both JV, but relatively the Shanghai GM JV research center had a technological progress compared to the Beijing Hyundai JV research center. This paper explains the differences in the technical capabilities of the two JV research center, despite the same type of JV, as the difference between the status of the Chinese partner and the global strategy of the parent company. SAIC, a Chinese partner in Shanghai GM as a top-tier company, not only has been strongly demanding technology transfer from GM since the beginning of the JV, but has also made efforts to improve its own technical capabilities. Meanwhile, BAIC, a Chines partner in Beijing Hyundai as a mid-tier company, has not been strongly demanding technology transfer and lacked its own research base. Regarding the parent company's global strategy, although both companies controlled the core areas of research and development by their parent companies, GM actively considered using the Chinese RV to develop Chinese and emerging country vehicles. On the other hand, Hyundai Motors responded to the localization demand of the Chinese government while paying more attention to preventing technology leakage through its independent research center in China. The above discussion shows that the process of globalization of a company is a political process in which the global strategy of the parent company and the demands of the stakeholders surrounding the subsidiary are collided and compromised, rather than a process in which the harmony and cooperation between the parent company and its subsidiaries are smoothly achieved as the parent company's policies are unilaterally implemented.

The Effects of Product Attributes, Brand and Corporate's Images on Consumer's Purchasing Intension - Focusing on Chinese Cellular Phone Markets in 9 Areas - (제품속성, 브랜드 및 기업 이미지가 소비자의 구매의도에 미치는 영향 -중국 9개 지역의 휴대폰시장을 중심으로-)

  • Jin, Cheng-Zhe;Park, Eui-Burm
    • International Area Studies Review
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    • v.12 no.3
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    • pp.367-390
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    • 2008
  • The Chinese cellular phone markets growth has the character which is two-sided gives the chance and threat in Korean mobile communication industry. This also demands the localization of the international marketing strategies which establishes in grasp of consumer consuming propensity and purchase intention. It is the goal that provides a strategic current point to the Korean enterprise which enter to China. To observe a test of hypothesis results concretely from empirical analysis with after words is same. The hypothesis 1, 'corporate image really will plus affect(+) in purchase intention' the hypothesis was adopted. The hypothesis 2, 'brand image really will plus affect(+) in purchase intention' also the hypothesis was adopted. The hypothesis 3, 'product attributes really will plus affect(+) in purchase intention' also the hypothesis was adopted. The other research hypothesis which sex and age were rejected, school was adopted partially, others was adopted. When about the consumer who is used from empirical analysis measurement items in the center application presents the strategies which is possible in fact.

A study on the modernity strategy to overcome the Western-centrism - By focusing on Lin, Hui-yin and Ling, Shu-hua's feminist literature (서구중심주의를 넘어서기 위한 현대성담론 - 임휘인(林徽因)과 능숙화(凌叔华)의 여성주의문학을 중심으로)

  • Ko, Hae-kyung
    • Cross-Cultural Studies
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    • v.25
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    • pp.363-389
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    • 2011
  • Modern Chinese Literature, the so-called 'feminist' is a very modern and the traditional criticism and took an important position in the double action. Because a woman's freedom from the bondage of traditional ethics of restoring the social status equal to men but to women does not give, that compared to men and women just the dimension of the problem of isolation is not just. It is dominated by yugajeok worldview by streamlining the whole Chinese society to build a modern society and the country was a critical task. However, multi-cultural life of Lin, Hui-yin and Ling, Shu-hua in the history of the world's attention to the shrine was worried attention to soils, rather than East-West dualism law by taking a mixture of both women in modern Chinese literature and Western literature from the center of efforts to overcome the traditional point hayeotdaneun feminist literature that may be different. Lin, Hui-yin and Ling, Shu-hua to overcome the Western-oriented culture really the true dream of China's globalization and localization could be regarded. She naesewotdeon the banner of feminist literature in the traditional 'anti feudal', 'free personality' silcheondoen under such slogans as well as women's liberation from traditional, male-oriented perspective away from the women's unique experiences and new understanding of the value of the superiority the concept of a woman, and was to create. In particular, the femininity of these women who traditionally associated with women and the unique culture - the creation of a new consciousness, a re-evaluation of traditional feminine skills and talents was to try to.

Single-Port Thoracic Surgery: A New Direction

  • Ng, Calvin S.H.
    • Journal of Chest Surgery
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    • v.47 no.4
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    • pp.327-332
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    • 2014
  • Single-port video-assisted thoracic surgery (VATS) has slowly established itself as an alternate surgical approach for the treatment of an increasingly wide range of thoracic conditions. The potential benefits of fewer surgical incisions, better cosmesis, and less postoperative pain and paraesthesia have led to the technique's popularity worldwide. The limited single small incision through which the surgeon has to operate poses challenges that are slowly being addressed by improvements in instrument design. Of note, instruments and video-camera systems that are narrower and angulated have made single-port VATS major lung resection easier to perform and learn. In the future, we may see the development of subcostal or embryonic natural orifice translumenal endoscopic surgery access, evolution in anaesthesia strategies, and cross-discipline imaging-assisted lesion localization for single-port VATS procedures.

A Study on the Korean Translation Strategy of 《Mu Yang Ai Hua, 牧羊哀話》 by Period (《목양애화(牧羊哀話)》의 시대별 한국어 번역 전략 연구)

  • Moon, dae-il
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.1
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    • pp.377-382
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    • 2021
  • 《Mu Yang Ai Hua, 牧羊哀話》 is known as the first Korean-sanctioned novel in the history of modern Chinese literature, and is famous for a novel created by the author himself visiting Korea and being inspired. The translation of 《牧羊哀話》 is constantly being re-translated (4 types). These translations also reflect the characteristics of each period, and the translation strategies used have their own characteristics. The results of the comparative analysis of the four types of translations in this study are as follows. The role A was published during the Japanese colonial period, and some parts were reduced and omitted according to the intent of the translator, and a foreignization translation strategy was used. B, C, and D have implemented content equivalence by utilizing many of the localization translation strategies, and added supplementary explanations in part to help readers understand. Since translation is a process of communication, it should not just convert the source text to the target text, but the target reader's response to the work should be the same as that of the reader. Therefore, translation must be able to understand the environment of the times and the readership, and it must use all possible methods to elicit the same emotion and empathy as the reader has read the original text. Therefore, translators need to use their nationalization and foreignization strategies at the same time based on their understanding of the target language and the politics, economy, history, culture, etc. of the destination country.

Characterization and Mapping of the Bovine FBP1 Gene

  • Guo, H.;Liu, W-S.;Takasuga, A.;Eyer, K.;Landrito, E.;Xu, Shang-zhong;Gao, X.;Ren, H-Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.9
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    • pp.1319-1326
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    • 2007
  • Fructose-1,6-bisphosphatase (FBP1) is a key regulatory enzyme of gluconeogenesis that catalyzes the hydrolysis of fructose-1,6-bisphosphate to generate fructose-6-phosphate and inorganic phosphate. Deficiency of fructose-1, 6-bisphosphatase is associated with fasting hypoglycemia and metabolic acidosis. The enzyme has been shown to occur in bacteria, fungi, plants and animals. The bovine FBP1 gene was cloned and characterized in this study. The full length (1,241 bp) FBP1 mRNA contained an open reading frame (ORF) encoding a protein of 338 amino acids, a 63 bp 5' untranslated region (UTR) and a 131 bp 3' UTR. The bovine FBP1 gene was 89%, 85%, 82%, 82% and 74% identical to the orthologs of pig, human, mouse, rat and zebra fish at mRNA level, and 97%, 96%, 94%, 93% and 91% identical at the protein level, respectively. This gene was broadly expressed in cattle with the highest level in testis, and the lowest level in heart. An intronic single nucleotide polymorphism (SNP) (A/G) was identified in the $5^{th}$ intron of the bovine FBP1 gene. Genotyping of 133 animals from four beef breeds revealed that the average frequency for allele A (A-base) was 0.7897 (0.7069-0.9107), while 0.2103 (0.0893-0.2931) for allele B (G-base). Our preliminary association study indicated that this SNP is significantly associated with traits of Average Daily Feed Intake (ADFI) and Carcass Length (CL) (p<0.01). In addition, the FBP1 gene was assigned on BTA8 by a hybrid radiation (RH) mapping method.

Diaspora and National policy - Focusing on Russian Diaspora and chinese Diaspora (디아스포라와 국가정책 - 러시안 디아스포라와 차이니즈 디아스포라를 중심으로)

  • Chun, Byung Kuk
    • Cross-Cultural Studies
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    • v.26
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    • pp.123-144
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    • 2012
  • In the modern society in which globalization and localization proceed simultaneously, diversified and rapid migration of diaspora makes a new from of boundary off the frame of the state and the nation. This new border accompanies cultural change and racial mixture; retains ethnic conflict, the gap between rich and poor, alienation and discrimination, as well as power conflict; and extends its influence. Nowadays, the countries all over the world including Korea face problem of Diaspora in numerous forms. And each country takes an approach to the problem of the diaspora in the aspects of their society, culture and political technology. This implies that most countries, without understanding the new form of border which is alive and dynamic, define and conceptualize the diaspora in the frame of one state and one nation to carry forward the policies accordingly, resulting in inequal, incomplete and awkward homogenization. This study aimed to explore the identity of the diaspora, the core for the problem solving. Of course, studies about the identity of the diaspora have been continued until today and many great outcomes have been achieved. Nevertheless, this study aimed to explore the identity of the diaspora and the national policies which have a close interrelationship with it. It is because the study ultimately aimed to highlight the interrelationship between the destination countries, Russia and China, and the diaspora, through the definition and the classification of Russian diaspora and Chinese diaspora and the analysis of the national policies about that. However, the intention was not to distinguish superiority through the comparison of the polices about the diaspora between two countries, but to focus on the diversity of the identity of the diaspora through defining each different diaspora and paralleling the policies. Second, the reason for looking into the diaspora policies of these two countries is because it is judged the changes in the diaspora policies of each country is one of the active factors for the changes in the identify of the diaspora of each country and it is the basic research for the study on the identity of the diaspora. New migration of diaspora changes the identity of the state, and the state makes the policies and enforce the policies, resulting in the influence on the diaspora. This interaction acts as the growth factor for the new boundary. The causes of Russian diaspora and Chinese diaspora show apparent 'differences'. In parallel with this, the policies about the diaspora in Russia and China arouse 'differences' to the diaspora. The variation of the identity of the diaspora made by these differences will suggest other viewpoints on the diaspora, and these viewpoints will become the foundation for solving the problem of the diaspora in the present times.

Thoughts on Chinese New Media Dance Triggered by the Use of 'Bullet Time' in the Premiere of "Dance Smash" (댄스 스매시 프로그램에 적용된 불릿타임의 효과와 중국 뉴미디어 무용의 과제)

  • Chen, Jinjing
    • Trans-
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    • v.8
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    • pp.79-93
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    • 2020
  • The main purpose of this article is to discuss the impact of "Dance Smash" TV show on Chinese dance, which uses the combination of dance and new media technology as the core content of the program. "Dance Smash", as a dance communication TV program for the public, first considers the entertainment attributes of variety shows. Spread the dance art on the basis of meeting the public's aesthetic needs, thereby expanding the popular living space of dance art. The use of 'moment of the storm' has let the general audience of non-dance majors feel the technical charm of dances, thus playing a healthy promotion role. However, whether "Bullet Time", a type of dance program that has had a successful case in the West, can also have a positive impact on the mass communication of dance in the localization of China, this is what questions and seeks of this article.

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