• The Journal of Korean Academy of Sensory Integration
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• v.21 no.1
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• pp.23-33
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• 2023

Objective : The purpose of this study is was to find ouetermine whether training to applying vibration stimulation to the biceps brachii of children in the late stages of spasticity hemiplegic cerebral palsy can helps to improve the function of the upper extremity. Methods : This The study was conducted on with three children with cerebral palsy, all between the ages of 13 and 15 years. Among the experimental research methods of used with individual subjects, an AB research design using multiple basic baseline individual experimental studies was used, and vibration stimulation was provided to the paralyzed hand during the intervention period. The An evaluation was conducted before and after each session used to measure the function of the upper extremity using was conducted after each session of the Rapael Smart Board and The Jebsen-Tayler hand function test and the Motor Activity Log (MAL) were conducted before and after the experiment. Results : As a result of measuring the smooth The average score and total scores of for using the Rapael Smart Board to measure the upper extremity function in following each therapeutic session using the Rafale smart pegboard showed that, Subject 3 did not showevidenced a no significant change in the average value, and but Subjects 1 and 2 did showed a significant changes in their average values. All three subjects showed significant changes in the Jepson-Taylor hand function test and in the Motor Activity Log test, as evaluated before and after the intervention. Conclusion : Training The using use of vibration stimulation showed a positive effect on in improving upper limb function and exercise in hemiplegia hemiplegic children with who had little experience on using their hemiplegic side.

• Genes and Genomics
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• v.40 no.12
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• pp.1339-1349
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• 2018

Cerebral palsy (CP) is a non-progressive neurological disease, of which susceptibility is linked to genetic and environmental risk factors. More and more studies have shown that CP might be caused by multiple genetic factors, similar to other neurodevelopmental disorders. Due to the high genetic heterogeneity of CP, we focused on investigating related molecular pathways. Ten children with CP were collected for whole-exome sequencing by next-generation sequencing (NGS) technology. Customized processes were used to identify potential pathogenic pathways and variants. Three pathways (axon guidance, transmission across chemical synapses, protein-protein interactions at synapses) with twenty-three genes were identified to be highly correlated with CP. This study showed that the three pathways associated with CP might be the molecular mechanism of pathogenesis. These findings could provide useful clues for developing pathway-based pharmacotherapies. Further studies are required to confirm potential roles for these pathways in the pathogenesis of CP.

• 재활복지
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• v.22 no.2
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• pp.175-212
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• 2018

The purpose of this study was to identify factors that affect the optimal selection of rehabilitation therapy and explore a processing model of rehabilitation decision-making for parents of children with cerebral palsy. A ground theory of Strauss and Corbin(1988)was used. Thus, collecting data was classified into open coding 140 concepts, 29 sub-categories and 8 categories. As a result of analysis, we identified that the main phenomenon was 'finding optimal therapy in trial and error' and parents experienced 6 stages including 'embarrassment', 'confusion', 'maximization', 'wandering', 'strategy', and 'balance'. Furthermore, 'rehabilitation-daily life balance' was a key category for continuation of treatment. This qualitative study discribed factors influencing determination of treatment and its continuation, and suggested a processing model of parents' decision- making for rehabilitation of their children.

• Physical Therapy Korea
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• v.19 no.3
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• pp.81-90
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• 2012

The aim of the current study was to assess the effectiveness of backward gait training on the treadmill in patients with spastic diplegic cerebral palsy (CP). Twelve patients with spastic diplegic CP participated in the study. An 8-week course of backward gait training was administered to the subjects for 3 days per week. Pre-intervention and post-intervention assessments of temporal-spatial gait parameters, the symmetry of the bilateral lower extremity weight bearing, and gross motor function were analyzed using motion analysis system, force plate, and Gross Motor Function Measurement (GMFM). There were significant improvements (p<.05) in the measures of both step length and right stance phase time. Joint kinematics showed increase in right hip abduction in initial contact and terminal swing, right hip external rotation and knee flexion in mid-swing, left ankle dorsiflexion in initial contact and terminal swing (p<.05). The symmetry of the bilateral lower extremity weight bearing and GMFM also significantly increased (p<.05). These findings indicate that backward gait training using a treadmill is beneficial for patients with spastic diplegic CP.

• Physical Therapy Korea
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• v.18 no.3
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• pp.16-25
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• 2011

This study aimed to evaluate factors related to the ability of ambulatory patients with cerebral palsy (CP) to walk over vertical and horizontal obstacles. Twenty patients with spastic CP who were able to walk independently for at least 10 m with or without walking devices were recruited for the study. Participants were required to walk over small obstacles (1, 4, and 8 cm in height or width; total of 6 conditions). A 'fail' was recorded when either the lower limbs or the walking device contacted the obstacle. Linear regression analyses were used to determine the effects of age, sex, walking devices, eyeglasses, subtype (hemiplegia or diplegia), ankle foot orthoses, functional level, and score of body mass index on the ability of obstacle crossing. Fifteen participants (75%) failed to adequately clear the foot or walking device over obstacles in at least 1 condition. The chance of failure in crossing vertical obstacle was affected by the use of ankle foot orthoses, eyeglasses, gender, and CP subtype (p<.05). The failure rate crossing horizontal obstacle was affected by CP subtype. These findings suggest that rehabilitation procedures should (1) consider the clinical characteristics of patients in order to prepare them to be more independent while performing daily activities, and (2) incorporate environmental conditions that patients encounter at home and in the community.

• Physical Therapy Korea
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• v.17 no.3
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• pp.40-47
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• 2010

The purposes of this study were to compare the reliability and validity of an 88-item version of the Gross Motor Function Measure (GMFM-88) and a 66-item version of GMFM (GMFM-66) in children with cerebral palsy (CP). The GMFM was completed in 154 children with CP (age range = 6~12). The internal consistency of the GMFM was calculated by Cronbach's ${\alpha}$ for judging reliability. The reliability of GMFM-88 and GMFM-66 were both above .99. The validity of measurement obtained by the GMFM was assessed by examining the unidimensionality of items and by comparing Gross Motor Function Classification System (GMFCS) levels with tests of the GMFM. Both the GMFM-88 and GMFM-66 were satisfied with unidimensionality. Discriminant validity was demonstrated on significant decreases in scores with increasing GMFCS levels in both measurements. However, GMFM-66 was a more sensitive discriminant in GMFCS level 1 and level 2 and in level 2 and level 4. This study reported a comparison of the reliability and validity of GMFM-88 and GMFM-66. The results of this study have implications for the information on the psychometric properties of two versions of GMFCS. This information will be useful for the selection of tools in clinics.

• The Journal of Korean Physical Therapy
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• v.14 no.3
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• pp.60-73
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• 2002

Spasticity is the most troublesome problems in the management in cerebral palsy. The purpose of this study was to observe the effect of FES to spasticity. 8 cerebral palsy children were selected for this study. Assessment was carried out before treatment for obtain baseline measurement of spasticity and reassessment were carried out at after 10th., 20th. treatment sessions and 24hours after treatment. The results of this study were as following that MAS scores were significantly reduced after 10th and 20th after treatment compared with pre-treatment. MAS scores were significantly reduced after 20th compared with pre-treatment. These results indicated that FES appears to reduce significantly MAS scores and maintained 24hours after treatment compared with pre-treatment.

• The Journal of Korean Physical Therapy
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• v.14 no.2
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• pp.51-64
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• 2002

Spasticity is the most troublesome problems in the management in cerebral palsy. The purpose of this study was to observe the effect of the FES and FIR to spasticity.8 cerebral palsy children were selected for this study. Assessment was carried out before treatment for obtain baseline measurement of spasticity and reassessment were carried out at after 10, 20 treatment sessions and 24hours after treatment. The results of this study were as fellowing : 1. MAS scores were significantly reduced after 10th and 20th after treatment compared with pre-treatment. 2. MAS scores were significantly reduced after 20th and maintained 24hours after treatment compared with pre-treatment These results indicated that FES and Far infrared appears to reduce significantly MAS scores and maintained 24hours after treatment compared with pre-treatment.

• 재활복지
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• v.18 no.4
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• pp.315-330
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• 2014

The purpose of this study was to verify the construct validity of the Sensory Profile for children with congenital cerebral palsy. Parents of 87 children(the ages of 3 to 10) with congenital cerebral palsy participated in this study. The data were analyzed through Winstep version 3.81 using the Rasch model to examine the uni-dimensionality of the fit of each item, the distribution of difficulty of each item, and the reliability and appropriateness of the rating scale. Based on a Rasch analysis, four out of the 87 children were considered to be inappropriate participants, and 15 item of the Sensory Profile was determined to be an inappropriate item. The items of high-level difficulty are needed as new items of the Korean Sensory Profile. The rating scale of three categories were appropriate than those of the five categories. The person and item separation reliability of three categories was above 0.90, which is a relatively excellent value. Finally, it will be need to verify of validity for Korean version of Sensory Profile, to develop new item of a high level of difficulty and convert into three point rating scale.

• Physical Therapy Korea
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• v.24 no.1
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• pp.51-60
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• 2017

Background: In cerebral palsy (CP), parents' quality of life and rearing attitude are considered possible factors that influence patients' quality of life, function level, and performance in daily activities. Despite these facts, little attention has been given to demonstrate a relation between these factors. Objects: This study aimed to demonstrate the relationship between parents' quality of life, functional level, and performance in daily activities, the quality of life of school-aged children with spastic CP. Methods: This study included 24 parents of school-aged children with spastic CP. The KIDSCREEN-52 and World Health Organization quality of life (WHOQOL)-BREF questionnaires (including physical, psychological, social, and environmental domains) were used as research tools to assess the quality-of-life profiles of the children with spastic CP and those of their parents, respectively. In addition, the function levels and performance in daily activities of the children with CP were assessed by using the gross motor function measure (GMFM) and modified Barthel index (MBI). Correlation and multiple regression analyses were performed to clarify the determinants of the quality of life of the children with CP. Results: The KIDSCREEN-52 score correlated with the total score (r=.735, p<.01) and all domains of the WHOQOL-BREF questionnaire (physical: r=.542, p<.01; psychological: r=.690, p<.01; social: r=.568, p<.01; and environmental: r=.783, p<.01). In addition, significant correlation was found between the KIDSCREEN-52 and MBI scores (r=.411, p<.05), and between the MBI and GMFM scores (r=.427, p<.05). After controlling for age, gender, paralytic type, GMFM, and MBI, the WHOQOL-BREF score ($R^2=.621$), particularly in the environmental domain ($R^2=.699$), remained independently related to the quality of life of the children. Conclusion: These findings suggest that the quality of life of school-aged children with spastic CP can be influenced by the quality of life of their parents. This study provides useful information for future studies to investigate the quality of life of children with CP.