• Title/Summary/Keyword: Chemical Quality Control

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Optimal Learning Control Combined with Quality Inferential Control for Batch and Semi-batch Processes

  • Chin, In-Sik;Lee, Kwang-Soon;Park, Jinhoon;Lee, Jay H.
    • 제어로봇시스템학회:학술대회논문집
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    • 1999.10a
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    • pp.57-60
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    • 1999
  • An optimal control technique designed for simultaneous tracking and quality control for batch processes. The proposed technique is designed by transforming quadratic-criterion based iterative learning control(Q-ILC) into linear quadratic control problem. For real-time quality inferential control, the quality is modeled by linear combination of control input around target qualify and then the relationship between quality and control input can be transformed into time-varying linear state space model. With this state space model, the real-time quality inferential control can be incorporated to LQ control Problem. As a consequence, both the quality variable as well as other controlled variables can progressively reduce their control error as the batch number increases while rejecting real-time disturbances, and finally reach the best achievable states dictated by a quadratic criterion even in case that there is significant model error Also the computational burden is much reduced since the most computation is calculated in off-line. The Proposed control technique is applied to a semi-batch reactor model where series-parallelreactions take place.

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Trends in System-level Research on Quality Control of Complex Herbal Formulation (복합 처방 품질 관리를 위한 시스템 차원의 연구 동향)

  • Lee, Doo Suk;Kim, Young Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.30 no.6
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    • pp.397-401
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    • 2016
  • The quality control is a fundamental procedure for the standardization of herbal medicine to guarantee the consistency of efficacy and safety. For a long time, the quality analysis of herbal medicine has been largely dependent on the routine sensory evaluation, such as taste, smell, color, and shape. However, with the recent development of analytical instruments, various scientific approaches have been introduced in this field. On the basis of the theory that the biological activities of herbal medicine are mainly contributed by its chemical compositions, several types of chemical markers have been suggested for the quality evaluation. In addition to the analytical methods for the specific marker compound(s), including analytical marker and active marker, recently, chemical fingerprinting, a method comparing the chromatographic pattern of the whole chemical components, has been developed and widely accepted as a reliable approach for the quality control of herbal medicine. Moreover, in order to exactly understand the relationship between complex compounds and their holistic biological activities in herbal medicine, unique strategies, such as "BECCs (bioactive equivalent combinatorial components)" and "PhytomicsQC" have been established. In this article, we give an overview of the several categories of chemical markers and the recent research trends for the quality evaluation of herbal medicine.

Advances in Chemical Process Control and Operation -A view experienced in joint university-industry projects

  • Ohshima, Masahiro
    • 제어로봇시스템학회:학술대회논문집
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    • 1994.10a
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    • pp.1.2-6
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    • 1994
  • A state or the arts in Japanese chemical process control is reviewed based on experience in applying advanced process control schemes to several industrial chemical processes. The applications validate model predictive control (MPC), the most popular advanced control scheme in the process control community, as, indeed, a powerful and practical control algorithm. However, at the same time, it is elucidated that MPC can solve only the control algorithm part of the problem and one needs chemical and systems engineering aspects to solve the entire problem. By illustrating several industrial process control problems, the need for chemical engineering aspects as well as the future direction for process control are addressed, especially in light or current attitudes toward product quality.

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Analysis of Zirconium and Nickel Based Alloys and Zirconium Oxides by Relative and Internal Monostandard Neutron Activation Analysis Methods

  • Shinde, Amol D.;Acharya, Raghunath;Reddy, Annareddy V.R.
    • Nuclear Engineering and Technology
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    • v.49 no.3
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    • pp.562-568
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    • 2017
  • Background: The chemical characterization of metallic alloys and oxides is conventionally carried out by wet chemical analytical methods and/or instrumental methods. Instrumental neutron activation analysis (INAA) is capable of analyzing samples nondestructively. As a part of a chemical quality control exercise, Zircaloys 2 and 4, nimonic alloy, and zirconium oxide samples were analyzed by two INAA methods. The samples of alloys and oxides were also analyzed by inductively coupled plasma optical emission spectroscopy (ICP-OES) and direct current Arc OES methods, respectively, for quality assurance purposes. The samples are important in various fields including nuclear technology. Methods: Samples were neutron irradiated using nuclear reactors, and the radioactive assay was carried out using high-resolution gamma-ray spectrometry. Major to trace mass fractions were determined using both relative and internal monostandard (IM) NAA methods as well as OES methods. Results: In the case of alloys, compositional analyses as well as concentrations of some trace elements were determined, whereas in the case of zirconium oxides, six trace elements were determined. For method validation, British Chemical Standard (BCS)-certified reference material 310/1 (a nimonic alloy) was analyzed using both relative INAA and IM-NAA methods. Conclusion: The results showed that IM-NAA and relative INAA methods can be used for nondestructive chemical quality control of alloys and oxide samples.

Effect of Mower Conditioner and Chemical Dry Agents on the Field Drying Rate of Mixed Pasture Plants Hay (Mower Conditioner와 건조제 처리에 의한 속성 양질 혼파목초 건초조제 효과)

  • Seo, S.;Chung, E.S.;Kim, J.G.;Kim, W.H.;Kang, W.S.;Lee, H.W.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.18 no.3
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    • pp.259-266
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    • 1998
  • A field experiment was carried out to determine the effects of mechanical and chemical drying agents at mowing on the field drying rate and hay quality of orchardgrass dominant pasture plants. The mower conditioner /chemical drying agent ($K_2CO_3$ 2% conditioning, $K_2CO_3$ 2% + conditioning and control) were treated at different harvest stages (late boot, heading and bloom stage) for hastening hay manufacture in 1996. After field dry, four square bales were made by hay baler, and the visual estimation and nutritive value of hay were evaluated after storing two months. The field drying rate of pasture plants was higher with delayed stage of harvest, and mechanical and mechanical + chemical, but chemical alone was very low. In mower conditioning, the duration of field dry was shortened by 0.5 to 1 day compared with $K_2CO_3$ and 1.5 to 2 days compared with control. The dry matter loss of hay was reduced by late harvest and mechanical, and mechanical + chemical, but the score by chemical alone was very low. The visual score (leafiness, green color, odor and softness) of hay after storage was high in mechanical and mechanical + chemical, but the score by chemical alone was very low. Nutritive value (ADF, NDF, digestibility, and relative feed value) of hay was also high with treatment of mechanical and mechanical + chemical, but the quality by chemical alone was similar compared with control. The quality of hay was very low when harvested at bloom stage. In conclusion, mower conditioning can enhance the field drying rate of orchardgrass dominant pasture plants, however the drying efficiency of chemical drying agent was very low. Harvesting at early heading to heading stage was recommened for manufacture of high quality hay.

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Control of Steaming Process for the Production of High Quality Red Ginseng (고급 홍삼 생산을 위한 증삼공정의 제어)

  • Kim, Sin;Na, Younghoon;Lee, Jietae;Cho, Wonhui
    • Korean Chemical Engineering Research
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    • v.52 no.5
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    • pp.587-591
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    • 2014
  • Experiments for a control method that enhances the yield to produce high quality red ginsengs have been performed. In the first steaming process of a series of processes to produce red ginsengs from raw ginsengs, there occur several undesirable defects on ginsengs such as cracks of ginseng body, inside cavity and inside white. These defects lead to deterioration in product qualities. Therefore an improved control method that minimizes these undesirable defects is needed in order to increase the yield of high quality red ginsengs. Until these days, the steaming process control methods such as controlling the steaming temperature and/or pressure have been studied. However, such control methods are not adequate enough to minimize the undesirable defects in steamed ginsengs. On the other hand, in this experiment, we suggest a control method that minimizes the undesirable defects through a weight control of steamed ginsengs, keeping the steaming temperature at $96{\sim}99^{\circ}C$ as usual. Experiments with the weight control show that amount of cracks on the steamed ginseng body can be reduced.

The Effects of Various Cement Type and Compositions on the Material Properties of high Strength Concrete (시멘트 특성의 변화가 고강도콘크리트의 재료특성에 미치는 영향)

  • 백상현;이종열;엄태선;임채용;안광원
    • Proceedings of the Korea Concrete Institute Conference
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    • 2000.04a
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    • pp.47-52
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    • 2000
  • Recently, it is very necessary the development of the manufacturing techniques for high strength concrete(HSC) for the large-scale size and good quality of civil structure. But, the manufacture and quality control of HSC of which shrinkage, heat of hydration and workability at construction filed are considered, is very difficult due to its low water-cement ratio and high quantity of unit cement content. In the present study, we tried to know and assess the influences of chemical and physical properties of cement on the material properties of HSC. We analyzed basic properties of 4 kinds of cement whose chemical and physical properties are different each other through various tests such as chemical analysis and mortal test. Also, we performed the assessment of the material properties of HSC for each dement by the test for the conditions of same mix design and similar compressive strength. From the results in the study, the assessment of the important quality factors of cement influencing the properties of HSC may be utilized to quality control of applied cement to manufacture the HSC of high quality.

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A Study on the Application in Site of the Concrete Using Fly Ash Produced in Combined Heat Power Plant (열병합발전소 플라이애쉬를 사용한 콘크리트의 현장적용에 관한 연구)

  • 김무한;이상수
    • Journal of the Korea Concrete Institute
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    • v.11 no.5
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    • pp.41-49
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    • 1999
  • This study dealt with the applicability and quality control of the concrete using fly ash produced in combined heat power in a construction site. Firstly, chemical and physical characteristics of the fly ash produced in combined heat power plant re analysed. Also, after investigating the properties of flesh and hardened concrete through various experiments, the fly ash concrete was placed in depositing construction in Ulsan Petrochemical Service Co. This field application was focussed on the quality control system in the site as production, placing and curing of concrete. As the result of this study, the quantity of CaO in the fly ash is relatively high based on the chemical analysis. The fly ash concrete showed slumping maintenance and high viscosity properties in the optimal mixing conditions (W/B:44~45%, S/a:$45\pm$2%, W:185kg/m). And, quality control and assurance of the fly ash concrete in actual site were verified by various testing methods.

VIBRATIONAL SPECTROSCOPY IN INDUSTRIAL CHEMICAL QUALITY CONTROL

  • Siesler, H.W.
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1081-1081
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    • 2001
  • The constant need for quality improvement and production rationalization in the chemical and related industries has led to the increasing replacement of conservative control procedures by more specific and environmentally compatible analytical techniques. In this respect, vibrational spectroscopy has developed over the last yews - in combination with new instrumental accessories and statistical evaluation procedures - to one of the most important analytical tools for industrial chemical quality control and process monitoring in a wide field of applications. In the present communication this potential is demonstrated in order to further support the implementation of mid-infrared (MIR), near-infrared (NIR) and Raman spectroscopy Primarily as industrial on-line tools. To this end the data of selected feasibility studies will be discussed in terms of the individual strengths of the different techniques for the respective application.

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Quality Control of Radiopharmaceutical (진단용 방사성 의약품의 정도관리)

  • An, Sung-Min;Hong, Tae-Kee;Ham, Jun-Cheol;Kim, Sung-Chul
    • The Journal of the Korea Contents Association
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    • v.9 no.11
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    • pp.240-246
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    • 2009
  • Quality control test in this field of study were carried out in 3 categories, radionuclidic purity, chemical purity and radiochemical purity. Also, indication efficiency was tested every 3 hours changed after binding the radiopharmaceutical to see how long the medicine is available for usage after indicating. The result showed that currently used radiopharmaceutical have good radionuclidic purity and chemical purity. However, radiochemical purity indication showed small differences depending on indication method and indication period. Radiopharmaceutical are indicated by treatment providers, so they need to pay more attention to the indication process and quality control to provide more efficient treatment.