• Title/Summary/Keyword: Channel 2

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Low-Voltage Activated $Ca^{2+}$ Current Carried via T-Type Channels in the Mouse Egg

  • Yang, Young-Sun;Park, Young-Geun;Cho, Soo-Wan;Cheong, Seung-Jin;Haan, Jae-Hee;Park, Choon-Ok;Hong, Seong-Geun
    • The Korean Journal of Physiology
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    • v.27 no.1
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    • pp.107-114
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    • 1993
  • Most of voltage operated $Ca^{2+}$ channels can be divided into three types (T-, N-, and L-type), according to the electrical and pharmacological properties. Their distribution is closely related to cell specific functions. Properties of the voltage activated $Ca^{2+}$ current in mouse eggs were examined to classify channel types and to deduce the function by using whole cell voltage clamp technique. $Ca^{2+}$ currents appeared below -40 mV and reached a maximum at -15 mV (half maximum was -31 mV), then decayed rapidly (inactivation time constant ${\tau}=28.2{\pm}9.59$ ms at -10 mV within 50 ms after the onset of step depolarization. Activation and inactivation of the $Ca^{2+}$ channel was steeply dependent on voltage, in a relatively low range of $-70\;mV{\sim}-10 mV,$ half maximum of activation was -31 mV and that of inactivation was -39 mV, respectively. This current was not decreased significantly by nifedipine, a specific dihydropyridine $Ca^{2+}$ channel blocker in the range of $1\;{\mu}M\;to\;100{\mu}M.$ The inhibitory effect of $Ni^{2+}\;on\;Ca^{2+}$ current was greater than that of $Cd^{2+}.$ The conductance of $Ba^{2+}$ through the channel was equal to or lower than that of $Ca^{2+}$ These results implied that $Ca^{2+}$ current activated at a lower voltage in the mouse egg is carried via a $Ca^{2+}$ channel with similar properties that of the T-type channel.

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A Protection Ratio with Composite Fade Margin for Detailed Frequency Coordination in Microwave Relay System Network

  • Suh, Kyoung-Whoan
    • Journal of electromagnetic engineering and science
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    • v.7 no.2
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    • pp.83-90
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    • 2007
  • In this paper, the formulation of the protection ratio based upon a composite fade margin and availability is newly presented for the detailed planning of frequency coordination in the microwave relay system network, and computed results for co-channel and adjacent channel protection ratios are illustrated over an actual system with 6.2 GHz. It is shown that the protection ratio to assure a quality of service can be expressed in terms of the composite fade margin, noise-to-interference ratio, net filter discrimination, and system parameters. In addition, the net filter discrimination, depending upon the transmitter spectrum mask and the overall receiver filter characteristic, has been examined to investigate the effect of the adjacent channel protection ratio caused by the adjacent channel interference. Regarding simulated results for 6.2 GHz, 60 km, 64-QAM, and N/I=6 dB at the bit error rate of $10^{-6}$, composite fade margin and co-channel protection ratio yield 25.14 and 50.3 dB, respectively. Also, the net filter discrimination of 26.5 dB and the adjacent channel protection ratio of 23.8 dB are obtained at the first adjacent channel of 30 MHz. The proposed method provides some merits in view of a comprehensive and practical application with more detailed and various system parameters needed to access the criteria for making the proper frequency coordination.

L3 Socialization of a Group of Mongolian Students Through the Use of a Written Communication Channel in Korea: A Case Study

  • Kim, Sun-Young
    • Cross-Cultural Studies
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    • v.19
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    • pp.411-444
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    • 2010
  • This paper explored the academic socialization of a group of Mongolian college students, learning Korean as their L3 (Third Language), by focusing on their uses of an electronic communication channel. From a perspective of the continua of bi-literacy, this case study investigated how Mongolian students who had limited exposure to a Korean learning community overcame academic challenges through the use of a written communication channel as a tool in the socialization process. Data were collected mainly through three methods: written products, interviews, and questionnaires. The results from this study were as follows. Interactional opportunities for these minority students were seriously constrained during the classroom practices in a Korean-speaking classroom. They also described the lack of communicative competence in Korean and the limited roles played by L2 (English) communication as key barriers to classroom practices. However, students' ways of engaging in electronic interactions differed widely in that they were able to broaden interactional circles by communicating their expertise and difficulties with their Korean peers through the electronic channel. More importantly, the communication pattern of "L2-L2/L3-L3" (on a L2-L3 continuum) emerging from data demonstrated how these students used a written channel as a socialization tool to mediate their learning process in a new community of learning. This study argues that a written communication channel should be taken as an essential part of teaching practices especially for foreign students who cannot speak Korean fluently in multi-cultural classes.

Comparative Study of a Multi-Channel Coils of Magnetic Resonance Imaging(MRI) Signal Intensities under Identical Parameters (동일한 조건의 자기공명검사에서 코일의 채널수 변화에 따른 신호강도의 평가)

  • Son, Soon-Yong
    • The Journal of the Korea Contents Association
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    • v.19 no.6
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    • pp.418-423
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    • 2019
  • The purpose of this study was to determine how the different number of channels of coils were related in the perceived signal intensity under identical parameters and area. Dedicated knee phantoms were scanned consecutively using both of the 16-channel and 8-channel knee coils. The T1 weighted and T2 weighted sequences were acquired using both coils to compare the signal intensities according to the number of channels. As a result, the 16-channel knee coils outperformed the 8-channel knee coils and the signal intensity was significantly increased in both of the T1 and T2 weighted images with the 16-channel coil. In conclusion, it is considered that better signal intensities and more clinical utility can be provided, when coils with more number of channels are used rather than using the coils with smaller number of channels.

A Non-Stationary Geometry-Based Cooperative Scattering Channel Model for MIMO Vehicle-to-Vehicle Communication Systems

  • Qiu, Bin;Xiao, Hailin
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.6
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    • pp.2838-2858
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    • 2019
  • Traditional channel models for vehicle-to-vehicle (V2V) communication usually assume fixed velocity in static scattering environment. In the realistic scenarios, however, time-variant velocity for V2V results in non-stationary statistical properties of wireless channels. Dynamic scatterers with random velocities and directions have been always utilized to depict the non-stationary statistical properties of the channel. In this paper, a non-stationary geometry-based cooperative scattering channel model is proposed for multiple-input multiple-output (MIMO) V2V communication systems, where a birth-death process is used to capture the appearance and disappearance dynamic properties of moving scatterers that reflect the time-variant time correlation and Doppler spectrum characteristics. Moreover, our model has more straight and concise to study the impact of the vehicular traffic density on channel characteristics and thus avoid complicated procedure in deriving the analytical expressions of the channel parameters and functions. The numerical results validate our analysis and demonstrate that setting important parameters of our model can appropriately build up more purposeful measurement campaigns in the future.

Study on optimum structure of free-breathing Polymer Electrolyte Membrane Fuel Cell (PEMFC) for robotic application (로봇용 자연급기형 연료전지의 최적구조에 관한 연구)

  • Choi, Jae-Hyuk;Park, Sang-Kyun
    • Journal of Advanced Marine Engineering and Technology
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    • v.30 no.2
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    • pp.231-238
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    • 2006
  • The performance of free-breathing polymer electrolyte membrane fuel cell (PEMFC) was studied experimentally and the effect of cathode separator structure on the cell performance was investigated. Cathode separators were used for the cell with $18cm^2$ active area. In channel type, the contact resistance is low, and the nature convection. which is strongly affected by the cross-sectional shape of cathode separator channel, is dominant in a cell performance. The maximum power density with $18cm^2$ active area is $105mW/cm^2$ using the 10mm depth and 2mm width channel. A computational analysis was optimum structure of free-breathing channel type PEMFC for robotic application.

A Design of Large Area Viewing LED Panel Control System (광시각용 LED 전광판제어 시스템 설계)

  • Lee, Su-Beom;Nam, Sang-Gil;Jo, Gyeong-Yeon;Kim, Jong-Jin
    • The Transactions of the Korea Information Processing Society
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    • v.6 no.5
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    • pp.1351-1361
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    • 1999
  • The wide spread of multimedia system demands a large area viewing display device which can inform a message to many people in open area. This paper is about the design of a large area viewing LED panel control system. The control system runs on 16 bit microprocessor MC68EC000 and has following functions: 16 line clock and time, 2 channel priority interrupt, 2 channel direct memory access, 2 channel 12 bit clock and timer, 2 channel infrared remocon receiver, 2 channel RS-232C with 16 byte FIFO, IBM PC/AT compatible keyboard interface, ISA bus, battery backuped real time clock, battery backuped 256 byte SRAM and watch dog timer. The core circuits are implemented to ASIC, considering lower cost, higher reliability, higher performance, smaller dimension, and lower power consumption. This is verified by simulation and fabricated in 0.6 um CMOS SOG processes. The total gate count is 39,083 and the clock frequency is 48 MGz. The fabricated ASIC is mounted on test board.

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Performance Analysis of Adaptive Channel Estimation Scheme in V2V Environments (V2V 환경에서 적응적 채널 추정 기법에 대한 성능 분석)

  • Lee, Jihye;Moon, Sangmi;Kwon, Soonho;Chu, Myeonghun;Bae, Sara;Kim, Hanjong;Kim, Cheolsung;Kim, Daejin;Hwang, Intae
    • Journal of the Institute of Electronics and Information Engineers
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    • v.54 no.8
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    • pp.26-33
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    • 2017
  • Vehicle communication can facilitate efficient coordination among vehicles on the road and enable future vehicular applications such as vehicle safety enhancement, infotainment, or even autonomous driving. In the $3^{rd}$ Generation Partnership Project (3GPP), many studies focus on long term evolution (LTE)-based vehicle communication. Because vehicle speed is high enough to cause severe channel distortion in vehicle-to-vehicle (V2V) environments. We can utilize channel estimation methods to approach a reliable vehicle communication systems. Conventional channel estimation schemes can be categorized as least-squares (LS), decision-directed channel estimation (DDCE), spectral temporal averaging (STA), and smoothing methods. In this study, we propose a smart channel estimation scheme in LTE-based V2V environments. The channel estimation scheme, based on an LTE uplink system, uses a demodulation reference signal (DMRS) as the pilot symbol. Unlike conventional channel estimation schemes, we propose an adaptive smoothing channel estimation scheme (ASCE) using quadratic smoothing (QS) of the pilot symbols, which estimates a channel with greater accuracy and adaptively estimates channels in data symbols. In simulation results, the proposed ASCE scheme shows improved overall performance in terms of the normalized mean square error (NMSE) and bit error rate (BER) relative to conventional schemes.

Properties of Single $K^{+}$ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

  • Park, Jin-Bong;Kim, Hee-Jeong;Cho, Myung-Haing;Lee, Hang;Park, Hong-Ki;Lee, Mun-Han;Ryu, Pan-Dong
    • The Korean Journal of Physiology
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    • v.29 no.1
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    • pp.13-27
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    • 1995
  • single $K^{+}$ channels of skeletal muscle from the rat and frog were into planar lipid bilayers and their properties were studied. Fusion was induced by an osmotic gradient. Of the four types of $K^{+}$ channels recorded, the two most frequently observed were a voltage and $Ca^{2+}-activated$ $K^{+}$ channel and a $K^{+}$ channel with a prominent conductance substate. The first $K^{+}$ channel was identified as the large $Ca^{2+}-activated$ $K^{+}$ (BK) channel because the open-state probability was increased with depolarization (e-fold change per $10.6{\pm}3.5$ mV, n=8) and internal $Ca^{2+}$ (half-activation at $16.7{\pm}3.8$ mV, n=8, pCa 4) and its conductance was large ($247{\pm}4.9$ pS, n=24 in 0.1 M KCI). Lifetime distributions of open- and closed-states could be fitted with single exponentials of several milliseconds. The mean open- and closed-lifetimes were linearly dependent on the intracellular $[Ca^{2+}]$ and $1/[Ca^{2+}]$, respectively. The second $K^{+}$ channel showed a conductance substate at $30{\sim}60%$ of the open state. Its current-voltage relation was linear in the range of $-80\;{\sim}\;+80\;mV$. The slope conductance of the substate and open-state were 40 and 144 pS in 0.2 M KCl, respectively. The channel was highly selective for $K^{+}$ over Cl. The open-state probability was weakly voltage-dependent (e-fold change per 35 mV. The lifetime distributions of open- and closed-states were fitted with two exponentials and the major gating occurred slowly at several hundred milliseconds. Based on the above results, we think the second type of $K^{+}$ channel is the sarcoplasmic reticulum $K^{+}$ (SRK) channel. In addition, both types of channel were also incorporated into the lipids extracted from the skeletal muscle. The channel properties recorded in the bilayers termed from synthetic and extracted lipids were qualitatively similar. Our data indicate that BK and SRK channels are rich in the skeletal muscle and their properties and regulation could be effectively studied in planar lipid bilayer.

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Application of the H Infinity Control Principle to the Sodium Ion Selective Gating Channel on Biological Excitable Membranes

  • Hirayama, Hirohumi
    • International Journal of Control, Automation, and Systems
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    • v.2 no.1
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    • pp.23-38
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    • 2004
  • We proposed the infinity control principle to evaluate the Biological function. The H infinity control was applied to the Sodium (Na) ion selective gating channel on the excitable cellular membrane of the neural system. The channel opening, closing and inactivation processes were expressed by movements of three gates and one inactivation blocking particle in the channel pore. The rate constants of the channel state transition were set to be voltage dependent. The temporal changes in amounts per unit membrane area of the channel states were expressed by means of eight differential equations. The biochemical mimetic used to complete the Na ion selective channel was regarded as noise. The control inputs for ejecting the blocking particle with plugging in the channel pore were set for the active transition from inactivated states to a closed or open state. By applying the H infinity control, we computed temporal changes in the channel states, observers, control inputs and the worst case noises. The present paper will be available for evaluating the noise filtering function of the biological signal transmission system.