• Title/Summary/Keyword: Change of solvent

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Protection by native edible plant extract MK-104 against kainate-induced neurotoxicity in mouse brain

  • Oh, Sang-Hee;Kim, Mee-Ree
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.04a
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    • pp.109.2-110
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    • 2003
  • The neuroprotective effect of solvent fraction of native edible plant MK-104 in the mice administered with kainate was evaluated using behavioral sign, neuronal injuries and biomarkers of oxidative stress. Mice, ICR male, were administered with the BFME through a gavage for 4 days consecutively, and on the 3rd day, kainate (450 mg/kg) was i.p. administered. The fraction(400 mg/kg) delayed the onset time of neurobehavioral change (p<0.01), reduced the severity of convulsion and lethality (p<0.05), and restored the level of GSH and lipid peroxidation in brain to control value. A similar protective action was also expressed by fraction-I (200 mg/kg), which showed a prominent protection against the neuronal damage in hippocampal CA1 and CA2 regions (p<0.01) caused by kainate injection. of TBARS value. Based on these results, BFME-I is suggested to contain a functional agent to prevent against oxidative stress in the brain of mice.

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Studies on Acid-Base Indicators in the Mixtures of Some Solvents(I) : Determination of Ampicillin, Amoxicillin and Cephalexin in Aqueous Organic Solvents (혼합용매중에서의 산-고기 지시약에 관한 연구(I) : 수-유기용매 혼합용매중 Ampicillin, Amoxicillin 및 Cephalexin의 정량)

  • 이왕규;심창구
    • YAKHAK HOEJI
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    • v.20 no.1
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    • pp.32-36
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    • 1976
  • The pH titration curves of ampicillin, amoxicillin and cephalexin in aqueous acetone, ethanol and N, N'-dimethylformamide by use of 0.02N-KOH solution showed that 80% acetone was the most effective solvent for alkali titration of them. The pH jumps of samples in 80% acetone were sharp enough to determine the contents of them by use in 80% acetone (9, 4) was coincided with each equivalent point of ampicillin, amoxicillin and cephalexin, but those of phenolphthalein, thymolphthalein, thymol blue and bgrom cresol purple were not. The color change of brom thymol blue at equivalent points was very clear except the case of amoxicillin that the determination of smaples in 80% acetone with 0.02 N-KOH solution by the aid of brom thymol blue could be available.

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Photo-grafting Dyeing of Wool Fabrics with Dimethacrylated Quinizarin Dye (반응성 염료의 광그라프트에 의한 양모직물의 염색)

  • Dong, Yuanyuan;Jang, Jin-Ho
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2012.03a
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    • pp.26-26
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    • 2012
  • The hydrophobic nature of the wool surface give rise to difficult penetration of dye molecules. Among all the methods of modification, graft polymerization is an attractive method to impart a variety of functional groups to a polymer. Grafting has been made by irradiating the light on the polymer in the presence of a solvent containing monomer. The energy source commonly used are high-energy electrons, X-rays, UV and visible light. UV irradiation is a relatively low-energy radiation in comparison with others since it has the least possibility to change bulk properties. In the present paper, a photo-reactive dye was synthesized from quinizarin by the reaction with methacryloyl chloride. The synthesized dye was continuously grafted onto wool fabric at room temperature by UV irradiation. Several key parameters including UV energy, dye concentration and pH have been examined to understand their influence on the photoreactive coloration.

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Fluorescence Enhancement of Ethidium Bromide by DNA Bases and Nucleosides

  • Pyun, Chong-Hong;Park, Su-Moon
    • Bulletin of the Korean Chemical Society
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    • v.10 no.2
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    • pp.142-147
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    • 1989
  • Fluorescence enhancements of ethidium bromide (EB) by solution species of low molecular weights such as DNA base molecules and nucleosides in water are reported. The degree of enhancements was determined by intensity as well as lifetime measurements for EB fluorescence. Experiments including solvent effects on absorbance and fluorescence spectra of EB, effects of protonation on the EB absorbance spectrum, and determination of equilibrium constants for EB-DNA bases have been performed to help explain the fluorescence enhancement. The results suggest that the excited state stabilization in the hydrophobic environment, the loss of torsional/vibrational energy of amino groups, and the change in the electronic transition characteristics are all responsible for the fluorescence enhancement.

Effect of Slurry Property on Preparation of Zirconia Film in Electrophoretic Deposition (전착법에서 용액특성이 지르코니아 막형성에 미치는 영향)

  • 김상우;이병호;손용배;송휴섭
    • Journal of the Korean Ceramic Society
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    • v.36 no.9
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    • pp.991-996
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    • 1999
  • Effect of solution property on the weight varation and microstructural change of film was studied by electrophoretic deposition in order to obtain a homogeneous and dense zirconia film. As a result of weight kinetics of film which obtained in alcohol or aqueous solution having different polarity experimental data showed large deviation from theoretical ones calculated by Zhang's kinetic model. It had been shown that the weight affecting factors was largely dependent on properties other than dielectric constant and viscosity of solvent zeta potential appiled field and time. In initial stage a main factor of the drastic weight increase was the capillary drag of porous substrate. The cause of weight decrease with time in aqueous solution after 300 s was attributed to the defect of film by sagging and electrolytic reaction. The electrolyte film which prepared in alcohol solution with good wetting for substrate had better homogeneous and dense microstructure than one in aqueous solution with high surface tension.

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A Study on the Synthesis and Mechanical Characteristics of NATM Resin (HATM 수지의 합성 및 기계적 특성에 관한 연구)

  • Kim, Ki-Jun
    • Journal of the Korean Applied Science and Technology
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    • v.22 no.4
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    • pp.355-361
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    • 2005
  • The physical characteristics of polyurethane were examined by SEM, FT-IR tensile strength and mole % [NCO/OH]. Growing concerns in the environment-friendly architecture and public works have led to the development of solvent-free formulations that can be cured and foamed in air. Compared with general packing materials, this resin is much stronger in intensity and much longer in durability. Polyurethane foam resins were mainly composed of polyol, MDI, silicone surfactant, fillers, catalyst and blowing agent. The rigid foam of polyurethane in mechanical characteristics were due to chain extender and the increase of mole % [NCO/OH]. The change in the microstructure of polyurethane should be taken into account when considering the process of construction and durability through the polyurethane polymer resin in lots of industries.

Necleophilic Substitution Reaction of Dansyl, Bansyl, Dabsyl Chloride (Dansyl, Bansyl, Dsbsyl Chloride의 친핵성 치환반응)

  • 김문식;채기수
    • The Korean Journal of Food And Nutrition
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    • v.5 no.1
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    • pp.23-32
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    • 1992
  • Kinetic studies of nucleophilic substitution reactions of dansyl, bansyl, dabsyl chlorides with pyridines have been investigated at $0^{\circ}C$ in a range of methanol-acetonitrile binary solvent mixtures. The order of magnitude for reactivity of substrates with pyridines in the same reaction condition is dabsyl chloride>dansyl chloride> bansyl chloride. The value of $\rho$n(-2.29~ -4.66) and $\beta$(0.537~0.901) associated with a change substituent in the nucleophile are large and indicate a relatively advanced bond formation in the transition state. Solvatochromic correlations were predicted the increase of bond formation transition state according to the increasing MeCN contents, showing the greater contribution of polarity polarizability ($\pi$*) than hydro-gen bond donar acidity($\alpha$). We conclude that the reactions of dansyl, bansyl, dabsyl chlorides with pyridines proceed via associative Sn2 type reaction mechanism.

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Efficient Bimodal Ring-opening Polymerization of ε-Caprolactone Catalyzed by Titanium Complexes with N-Alkoxy-β-ketoiminate Ligands

  • Cho, Min-Ho;Yoon, Jin-San;Lee, Ik-Mo
    • Bulletin of the Korean Chemical Society
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    • v.28 no.12
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    • pp.2471-2476
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    • 2007
  • A series of titanium complexes containing terdentate β-ketoiminate ligands were found to be efficient for the ring-opening polymerization of ε-caprolactone (ε-CL), producing poly(ε-caprolactone) (PCL) with bimodal distribution. Steric factors imposed by methyl substituents on the back bone of the alkoxy group affected significantly the polymerization rate and physical properties of the resulting PCL. Intra- and intermolecular transesterifications rather than disproportional rearrangements were responsible for the bimodal behavior and for the change in the molecular weight (Mw). Dilution with toluene reduced yield, and lowered polydispersity (PDI) and Mw of PCL, while the catalytic activities of the dimeric complex, [Ti(Oi-Pr)2(N-alkoxy-β- ketoiminate)]2 and Ti(Oi-Pr)4 were not sensitive to the added solvent. The dimeric complex showed living character, while other catalysts suffered from chain termination reactions.

PEDOT:PSS Thin Films with Different Pattern Structures Prepared Using Colloidal Template

  • Yu, Jung-Hoon;Lee, Jin-Su;Nam, Sang-Hun;Boo, Jin-Hyo
    • Applied Science and Convergence Technology
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    • v.23 no.5
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    • pp.254-260
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    • 2014
  • Organic solar cells have attracted extensive attention as a promising approach for cost-effective photovoltaic devices. However, organic solar cell has disadvantage of low power conversion efficiency in comparison with other type of solar cell, due to the recombination ratio of hole and electron is too large in the active layer. Thus we have change the surface structure of PEDOT:PSS layers to improve the current density by colloidal lithography method using various-size of polystyrene sphere. The two types of coating method were applied to fabricate the different pattern shape and height, such as spin coating and drop casting. Using the organic solvent, we easily eliminate the PS sphere and could make the varied pattern shapes by controlling the wet etching time. Also we have measured the electrical properties of patterned PEDOT:PSS film to check whether it is suitable for organic photovoltaics.

A Study on the Scientific Conservation of Buried-Fabrics form old Tombs -cleaning and ironing- (출토직물의 과학적 보존 처리에 관한 연구 -세탁방법과 다림질 방법-)

  • 배순화;이미식
    • Journal of the Korean Society of Clothing and Textiles
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    • v.23 no.7
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    • pp.987-997
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    • 1999
  • The purpose of this study was finding out the appropriate cleaning method for buried fabrics from old tombs focusing on the conservation of textiles. Cleaning effects and physical properties change depending on cleaning method have been analysed, The following results were obtained from this study : 1. Wet cleaning showed better effect on the cleaning of fabrics compared to solvent cleaning which meant more water-soluble soils existed than oily soils. 2. All the cleaning methods used did not cause any distorsion or shrinkage to the fabrics because fabrics had been stabilized for a long time 3. Addition of detergent to cleaning system decreased the friction of fiber during cleaning rocess so that the damage of fabrics could be minimized., 4. Ironing is an undesirable process because heat remarkably weakened fibers.

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