• Title/Summary/Keyword: Chang-Pu

Search Result 114, Processing Time 0.032 seconds

Comparison of the Therapeutic Efficacy of Rhizoma Alismatis, Fructus Crataegi, Fructus Lycii, Radix Curcumae, Radix Salviae Miltiorrhizae, Herba Artemisiae Scopariae on the Experimental Cellular Model of Nonalcoholic Fatty Liver Disease (비알코올성 지방간 세포 모델에 대한 택사, 산사, 구기자, 울금, 단삼, 인진의 효능 비교)

  • Han, Chang-Woo;Joo, Myung-Soo;Lee, Jang-Hoon
    • The Journal of Internal Korean Medicine
    • /
    • v.33 no.4
    • /
    • pp.533-542
    • /
    • 2012
  • Objectives : We try to compared the efficacy of six herbal medicines, Rhizoma Alismatis (RA), Fructus Crataegi (FC), Fructus Lycii (FL), Radix Curcumae (RC), Radix Salviae Miltiorrhizae (RSM), and Herba Artemisiae Scopariae (HAS), constituting KHchunggan-tang which was previously proven to be hepatoprotective on non-alcoholic fatty liver disease with combined properties of cellular steatosis, ROS production, and cytoprotection. Methods : HepG2 cells were pretreated with aqueous extracts of the six herb medicines at concentrations of 1, 10, 50 and 100 ${\mu}g/ml$ each, and treated with 0.5 mM palmitate consecutively. After 21 hrs, cell viability was assessed using MTT assay, and the percentage of cells with sub-G1 DNA content was measured using fluorescence-activated cell sorting after propidium iodide staining. Results : The first three extracts, RA, FC, and FL restored cell viability reduced by palmitate in MTT assay, and RA, FC, FL and RC inhibited palmitate-induced apoptosis in sub-G1 analysis. FL showed relatively weak potential only at tested maximal dose, and RA showed the greatest higher efficacy on this experimental cellular model of nonalcoholic fatty liver disease. Conclusions : According to this comparative experiment, Rhizoma Alismatis seems to have the most powerful potential among the six herbs constituting KHchunggan-tang, and consecutive further study seems to be required for more standardized and effective clinical application of KHchunggan-tang for treatment of non-alcoholic fatty liver disease.

A Study on Optimization of Manufacture Conditions for Water Treatment Membrane by Using Electrospinning Method (전기방사법을 이용한 수처리용 막 제조 조건 최적화 연구)

  • Lee, Sang Hyun;Choi, Sung Yeol;Chang, Soon Woong;Kim, Sung Su
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.39 no.8
    • /
    • pp.456-461
    • /
    • 2017
  • In this study, nano fibers with various physical properties were materialized by using a variety of polymers [PAN (Polyacrylonitrile), PU (Polyuretane), PSU (Polysulfone)] which are raw materials of dope solution manufactured for electrospinning and solvents [NMP (N-methyl-2 pyrrolidone), DMF (Dimethylformamide)] and evaluated characteristics of their flux and SS (Suspended Solids) separation and then ascertained application of manufactured fibers as separation membrane for water treatment. In this study, analysis of surface of manufactured material was carried out through SEM analysis to ascertain the cause of flux and SS separation performance by checking diameter, uniformity and straightness of fiber. If additive is used in manufacturing nano fiber water treatment separation membrane, it is expected to solve problems such as membrane fouling and mechanical strength and to be used as basic factor for manufacturing separation membrane with catalyst function added.

DESIGN OPTIMIZATION OF RADIATION SHIELDING STRUCTURE FOR LEAD SLOWING-DOWN SPECTROMETER SYSTEM

  • KIM, JEONG DONG;AHN, SANGJOON;LEE, YONG DEOK;PARK, CHANG JE
    • Nuclear Engineering and Technology
    • /
    • v.47 no.3
    • /
    • pp.380-387
    • /
    • 2015
  • A lead slowing-down spectrometer (LSDS) system is a promising nondestructive assay technique that enables a quantitative measurement of the isotopic contents of major fissile isotopes in spent nuclear fuel and its pyroprocessing counterparts, such as $^{235}U$, $^{239}Pu$, $^{241}Pu$, and, potentially, minor actinides. The LSDS system currently under development at the Korea Atomic Energy Research Institute (Daejeon, Korea) is planned to utilize a high-flux ($>10^{12}n/cm^2{\cdot}s$) neutron source comprised of a high-energy (30 MeV)/high-current (~2 A) electron beam and a heavy metal target, which results in a very intense and complex radiation field for the facility, thus demanding structural shielding to guarantee the safety. Optimization of the structural shielding design was conducted using MCNPX for neutron dose rate evaluation of several representative hypothetical designs. In order to satisfy the construction cost and neutron attenuation capability of the facility, while simultaneously achieving the aimed dose rate limit (< $0.06{\mu}Sv/h$), a few shielding materials [high-density polyethylene (HDPE)eBorax, $B_4C$, and $Li_2CO_3$] were considered for the main neutron absorber layer, which is encapsulated within the double-sided concrete wall. The MCNP simulation indicated that HDPE-Borax is the most efficient among the aforementioned candidate materials, and the combined thickness of the shielding layers should exceed 100 cm to satisfy the dose limit on the outside surface of the shielding wall of the facility when limiting the thickness of the HDPE-Borax intermediate layer to below 5 cm. However, the shielding wall must include the instrumentation and installation holes for the LSDS system. The radiation leakage through the holes was substantially mitigated by adopting a zigzag-shape with concrete covers on both sides. The suggested optimized design of the shielding structure satisfies the dose rate limit and can be used for the construction of a facility in the near future.

CERAMOGRAPHY ANALYSIS OF MOX FUEL RODS AFTER AN IRRADIATION TEST

  • Kim, Han-Soo;Jong, Chang-Yong;Lee, Byung-Ho;Oh, Jae-Yong;Koo, Yang-Hyun
    • Nuclear Engineering and Technology
    • /
    • v.42 no.5
    • /
    • pp.576-581
    • /
    • 2010
  • KAERI (Korea Atomic Energy Research Institute) fabricated MOX (Mixed Oxide) fuel pellets as a cooperation project with PSI (Paul Scherrer Institut) for an irradiation test in the Halden reactor. The MOX pellets were fitted into fuel rods that included instrumentation for measurement in IFE (Institutt for Energiteknikk). The fuel rods were assembled into the test rig and irradiated in the Halden reactor up to 50 MWd/kgHM. The irradiated fuel rods were transported to the IFE, where ceramography was carried out. The fuel rods were cut transversely at the relatively higher burn-up locations and then the radial cross sections were observed. Micrographs were analyzed using an image analysis program and grain sizes along the radial direction were measured by the linear intercept method. Radial cracks in the irradiated MOX were observed that were generally circumferentially closed at the pellet periphery and open in the hot central region. A circumferential crack was formed along the boundary between the dark central and the outer regions. The inner surface of the cladding was covered with an oxide layer. Pu-rich spots were observed in the outer region of the fuel pellets. The spots were surrounded by many small pores and contained some big pores inside. Metallic fission product precipitates were observed mainly in the central region and in the inside of the Pu spots. The average areal fractions of the metallic precipitates at the radial cross section were 0.41% for rod 6 and 0.32% for rod 3. In the periphery, pore density smaller than 2 ${\mu}m$ was higher than that of the other regions. The grain growth occurred from 10 ${\mu}m$ to 12 ${\mu}m$ in the central region of rod 6 during irradiation.

Evaluation of the Commonly Misused Chinese Crude Drug Species (일반적(一般的)으로 오용(誤用)된 생약종(生藥種)의 평가(評價))

  • Chang, Yuan Shiun
    • Journal of Haehwa Medicine
    • /
    • v.4 no.2
    • /
    • pp.333-333
    • /
    • 1996
  • Chinese medicine is a precious treasure inherited from ancient ancestors. It is accredited for the prosperous growth of the Chinese nations. However, the descriptions of the herbs in the ancient herbal are not in detail and the great numbers of herbs used which grows in wide geographic areas together with various local folk names, new substitutes and new folk medicines had increased, many Chinese herbs are composed of herbs that are labeled with identical names but actually are of different origins and different grades. Similar situation had occurred in China, japan and Korea In Taiwan, misused Chinese crude drugs are also very common in the past. This phenomenon had caused a lot of confusion and had great influence the clinical efficacy of the treatment. In the past, Professor Hong Yen Hsu, Na Chi, Woei Song Kan and Kung Yin Yen had studied the origins of Chinese crude drugs in Taiwan based on the morphological identification and found that the origins of Ma-Tou-Ling, Pu-Kung-Yin, Tu-Chung, Wang-Pu-Liu-Hsing, Pan-lan-Ken, Niu-Chi, Fang-Chi, Huang-Chi, PienHsiu and Sha Wan-Tzi are different from that of the species used in mainland China. In order to assure the quality and clinical efficacy of the crude drugs, besides the traditional morphological methods, we bad recently combined modem chemical and pharma-cological methods to assess drug quality. Drugs that have been evaluated without effects should be abandoned. The species of those commonly misued crude drugs used in compound formula preparations are also identified Based on the pharmacological results, a suitable species is recommended so as to improve the clinical efficacy of those preparations. In this paper, we like to report our recent studies on Niu Chi(Achyranthis Bidentatae Radix, Cyathulae Radix and Strobilanthis Radix). Fang-Chi(Arstolochiae Fangchi Radix, Stephaniae Tetrandrae Radix and Cocculus Radix) and Huang-Chi(Astragali Radix and Hedysari Radix) using comparative pharmacognosy methods.

  • PDF

Ontology Modeling and Its Application for Managing Control Points (기준점 관리를 위한 온톨로지 모델링과 적용 방안)

  • Cui, Yulan;Hwang, Hyun-Suk;Shin, Seong-Hyun;Suh, Yong-Cheol;Kim, Chang-Soo
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.11 no.3
    • /
    • pp.34-42
    • /
    • 2008
  • The control points are important assets of countries which express the most accurate location information that is used in surveying land and other measurements. The location information has played an important role in our daily lives with the development of ubiquitous technology. While many researchers have recently applied new technology like RFID(Radio-Frequency Identification) to the effective management of control points, the research into data retrieval and the interoperability of control point data is still primitive step. Therefore, we construct a data modeling to effectively manage control points using ontology data structure and focus on semantic retrieval method. Our retrieval system can provide the inferred and associated information among data using Prot$\acute{e}$g$\acute{e}$-OWL tool. Our system has advantages in reducing the number of repeated queries by hierarchy searching and improving the searching time by association searching. Also, we propose an effective method to construct retrieval systems being able to edit items of categories and properties without editing the related codes.

  • PDF

Ferroelectric Properties of Pb[(Zr,Sn)Ti]NbO3 Thin Films with Various Composition Ratio (조성비에 따른 Pb[(Zr,Sn)Ti]NbO3 박막의 강유전 특성)

  • Choi, Woo-Chang;Choi, Hyek-Hwan;Lee, Myoung-Kyo;Kwon, Tae-Ha
    • Journal of Sensor Science and Technology
    • /
    • v.11 no.1
    • /
    • pp.48-53
    • /
    • 2002
  • Ferroelectric $Pb_{0.99}[(Zr_{0.6}Sn_{0.4})_{1-x}Ti_x]_{0.98}Nb_{0.02}O_3$(PNZST) thin films were deposited by a RF magnetron sputtering on $(La_{0.5}Sr_{0.5})CoO_3$(LSCO)/Pt/Ti/$SiO_2$/Si substrate using a PNZST target with excess PbO of 10 mole%. The crystallinity and electrical properties of the thin films with various composition ratio were investigated. The thin films deposited at the substrate temperature of $500^{\circ}C$ and the power of 80 W were crystallized to a perovskite phase after rapid thermal annealing(RTA) at $650^{\circ}C$ for 10 seconds in air. A PNZST thin films with Ti of 10 mole% showed the good crystallinity and ferroelectric properties. The remanent polarization and coercive field of the PNZST capacitor were about $20\;{\mu}C/cm^2$ and 50 kV/cm, respectively. The reduction of the polarization after $2.2{\times}10^9$ switching cycles was less than 10%.

Narrative Time and Typographical Space: Towards a Typographical Narratology

  • Kim Chang-Rea;Park Jung-Sik
    • Archives of design research
    • /
    • v.19 no.3 s.65
    • /
    • pp.59-70
    • /
    • 2006
  • Narratologists have long raised the question of how narrative theories could be applied to other disciplines that involve stories and storytelling. Focusing on recently revitalized concepts of space, sequence, and story, this article attempts to illustrate narrative constructions in various fields of arts and humanities and examine them particularly in typographical works. Through the concept of narrativity, this article highlights the prevalent uses of narrative in typography and scrutinizes the ways in which a sense of storyness is forming and emerging in some typographical works. Particularly emphasized are the importance of and interplay between the formal and cultural attributes of narrative that transform the spatial world of visual images to the temporal world of stories. Narrative is arguably the most familiar, interesting, and effective medium of communication regardless of age, race, and culture, and can be critically rethought to apply to typography and design.

  • PDF

A Comparative Study on the Proliferation Resistance of Nuclear Fuel Cycles

  • Chang, H.L.;Ko, W.I.;Lee, Y.D.;Lee, K.S.;Kim, H.D.
    • Proceedings of the Korean Radioactive Waste Society Conference
    • /
    • 2009.11a
    • /
    • pp.53-54
    • /
    • 2009
  • The preliminary quantitative analysis of proliferation resistance for the five nuclear fuel cycles demonstrated that the thermal MOX fuel cycle is most vulnerable to proliferation due to the presence of pure $PuO_2$ in the fuel cycle, while the once-through fuel cycle has the highest proliferation resistance. The innovative next generation fuel cycles such as Pyro-SFR and Wet-SFR were found to have similar levels of proliferation resistance to that of the DUPIC fuel cycle which is believed to have proliferation resistance strong enough for commercial deployment. The sensitivity analysis also demonstrated the effectiveness of the proposed methodology in applying to existing and/or newly developing nuclear fuel cycles so as to improve the proliferation resistance characteristic of the fuel cycle systems.

  • PDF

Single Interpolation for Multi-sample Prediction in Intra Coding of HEVC (단일 보간을 이용한 화면내 복수 샘플 예측)

  • Lee, Jinho;Kim, Hui Yong;Lim, Sung-Chang;Lee, Hahyun;Choi, Jin Soo
    • Proceedings of the Korean Society of Broadcast Engineers Conference
    • /
    • 2011.07a
    • /
    • pp.184-187
    • /
    • 2011
  • 본 논문에서는 화면내 예측의 계산 복잡도를 감소시키기 위한 방법을 제안한다. HM2.0 의 화면내 예측방법인 각도에 의한 예측(Angular prediction)은 예측 대상블록 내부의 각 샘플이 예측하기 위해 사용하는 참조샘플로부터 정수단위의 위치에 있지 않을 경우 참조 샘플들을 보간 하여 예측을 수행한다. 이러한 방법은 예측 대상 블록의 크기가 커질수록 보간 하는 횟수가 증가하고 계산 복잡도가 증가하는 단점이 있다. 제안하는 방법은 한번의 보간으로 복수의 샘플들을 예측함으로써 보간 횟수를 줄이고 결과적으로 계산의 복잡도를 줄인다. PU_32x32 에 대해 제안하는 방법을 적용하였을 경우, 보간하는 횟수는 HM2.0 대비 1/2 배 또는 1/4 배 가까이 감소하고 성능 저하는 High-Efficiency(HE)에서 0.1% 또는 0.2% 정도로 미미하게 나타났다.

  • PDF