• Title/Summary/Keyword: Cerium(III) chloride

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A New Approach for Thermodynamic Study on the Binding of Human Serum Albumin with Cerium Chloride

  • Rezaei Behbehani, G.;Divsalar, A.;Saboury, A.A.;Faridbod, F.;Ganjali, M.R.
    • Bulletin of the Korean Chemical Society
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    • v.30 no.6
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    • pp.1262-1266
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    • 2009
  • Thermodynamics of the interaction between Cerium (III) chloride, $Ce^{3+}$, with Human Serum Albumin, HSA, was investigated at pH 7.0 and $27\;{^{\circ}C}$ in phosphate buffer by isothermal titration calorimetry. Our recently solvation model was used to reproduce the enthalpies of HSA interaction by $Ce^{3+}$. The solvation parameters recovered from our new model, attributed to the structural change of HSA and its biological activity. The interaction of HSA with $Ce^{3+}$ showed a set of two binding sites with negative cooperativity. $Ce^{3+}$ interacts with multiple sites on HSA affecting its biochemical and biophysical properties.

Kinetics and Mechanism of Ruthenium(III) Catalyzed Oxidation of Butanone and Uncatalyzed Oxidation of Cychlohexanone by Cerium(IV) in Acid Sulphate Medium

  • Sharma, Priyamvada;Hemkar, Shalini;Khandelwal, C.L.;Sharma, P.D.
    • Journal of the Korean Chemical Society
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    • v.56 no.1
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    • pp.28-33
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    • 2012
  • The kinetics of ruthenium(III) chloride catalyzed oxidation of butanone and uncatalyzed oxidation of cyclohexanone by cerium(IV) in sulphuric acid medium have been studied. The kinetic rate law(I) in case of butanone conforms to the proposed mechanism. $$-\frac{1}{2}\frac{d[Ce^{IV}]}{dt}=\frac{kK[Ru^{III}][butanone]}{1+K[butanone]}$$ (1). However, oxidation of cyclohexanone in absence of catalyst accounts for the rate eqn. (2). $$-\frac{1}{2}\frac{[Ce^{IV}]}{dt}=\frac{(k_1+k_1K^'[H^+])[Ce^{IV}][Cyclohexanone]}{1+K_3[HSO_4^-]}$$ (2) Kinetics and activation parameters have been evaluated conventionally. Kinetically preferred mode of reaction is via ketonic and not the enolic forms.