• 가정∙방문간호학회지
• /
• 제28권2호
• /
• pp.144-153
• /
• 2021

Purpose: The purpose of this study was to find out the relationship between health concern, knowledge of cardio-cerebrovascular disease, and health-promoting behaviors among the elderly in the community. Method: The subjects of the study were 142 senior citizens aged 65 years or older in Cheongju-si, Chungcheong-do. Data were collected using structured questionnaires that included questions on the general characteristics, health concerns, knowledge of cardio-cerebrovascular disease, and health-promoting behaviors. The collected data were analyzed by the statistical program SPSS 20.0. The frequencies, percentages, averages, and standard deviations of the collected data were analyzed using a t-test, ANOVA, Mann Whitney U test, and Pearson's correlation coefficient, basing on the purpose of the study. The Scheffe test was carried out as a posteriori test. Result: The elderly were found to have a high health concern, but their knowledge of cardio-cerebrovascular disease was low, and their health-promoting behaviors were above the intermediate level. There was a significant positive correlation between each variable, which means that the higher the health concern was, the more knowledge an individual had of cardio-cerebrovascular disease, and the more health-promoting behaviors one had. Conclusion: This suggests that the elderly in the community should be encouraged to engage in the actions that promote their health by raising their level of health concern and awareness of diseases through health education, basing on their individual characteristics.

• Nutrition Research and Practice
• /
• 제17권2호
• /
• pp.371-385
• /
• 2023

BACKGROUND/OBJECTIVES: Soy isoflavone (SIF) and soy lecithin (SL) have beneficial effects on many chronic diseases, including neurodegenerative diseases. Regretfully, there is little evidence to show the combined effects of these soy extractives on the impairment of cognition and abnormal cerebral blood flow (CBF). This study examined the optimal combination dose of SIF + SL to provide evidence for improving CBF and protecting cerebrovascular endothelial cells. MATERIALS/METHODS: In vivo study, SIF50 + SL40, SIF50 + SL80 and SIF50 + SL160 groups were obtained. Morris water maze, laser speckle contrast imaging (LSCI), and hematoxylin-eosin staining were used to detect learning and memory impairment, CBF, and damage to the cerebrovascular tissue in rat. The 8-hydroxy-2'-deoxyguanosine (8-OHdG) and the oxidized glutathione (GSSG) were detected. The anti-oxidative damage index of superoxide dismutase (SOD) and glutathione (GSH) in the serum of an animal model was also tested. In vitro study, an immortalized mouse brain endothelial cell line (bEND.3 cells) was used to confirm the cerebrovascular endothelial cell protection of SIF + SL. In this study, 50 µM of Gen were used, while the 25, 50, or 100 µM of SL for different incubation times were selected first. The intracellular levels of 8-OHdG, SOD, GSH, and GSSG were also detected in the cells. RESULTS: In vivo study, SIF + SL could increase the target crossing times significantly and shorten the total swimming distance of rats. The CBF in the rats of the SIF50 + SL40 group and SIF50 + SL160 group was enhanced. Pathological changes, such as attenuation of the endothelium in cerebral vessels were much less in the SIF50 + SL40 group and SIF50 + SL160 group. The 8-OHdG was reduced in the SIF50 + SL40 group. The GSSG showed a significant decrease in all SIF + SL pretreatment groups, but the GSH showed an opposite result. SOD was upregulated by SIF + SL pretreatment. Different combinations of Genistein (Gen)+SL, the secondary proof of health benefits found in vivo study, showed they have effective anti-oxidation and less side reaction on protecting cerebrovascular endothelial cell. SIF50 + SL40 in rats experiment and Gen50 + SL25 in cell test were the optimum joint doses on alleviating cognitive impairment and regulating CBF through protecting cerebrovascular tissue by its antioxidant activity. CONCLUSIONS: SIF+SL could significantly prevent cognitive defect induced by β-Amyloid through regulating CBF. This kind of effect might be attributed to its antioxidant activity on protecting cerebral vessels.

• 한국컴퓨터정보학회논문지
• /
• 제11권6호
• /
• pp.107-111
• /
• 2006

IT산업 발전에 따라 일상생활은 점차 편리해지고 있으며 이와 비례하여 환경오염의 확산과 각종 질병들에 대한 위험도 점차 높아지고 있다. 인간의 생명을 위협하는 위험한 질병 중에는 사전에 예방하지 않으면 돌이킬 수 없는 사태로 확산되기도 하지만 바쁜 현대인들에게는 자신의 건강상태를 사전에 파악하고 관리하기 힘든 실정이다. 이에 유비쿼터스 환경에 접어든 IT기술을 바탕으로 의료진단 및 예방 시스템을 구축하여 사용자들이 센서를 통해 컴퓨터를 직접 이용하지 않더라도 자신의 건강상태를 유지 관리할 필요가 있다. 그러므로 본 논문에서는 이와 같이 유비궈터스 환경으로 변화해가는 기술적 변화를 바탕으로 의료 진단 및 예방이 가능한 시스템 구축을 위한 모델로서 뇌혈관 질환에 대한 모델을 제시하고자 한다. 또한, 이를 통해 향후 구축하고자 하는 u-헬스 케어 의료진단 시스템 구축 모델에 활용하고자 하며, 본 모델을 통해 의료정보를 활용한 산업 발전과 인류의 편이성 증대 및 건강상태의 주기적 검사를 통해 향상된 복지문화를 유도할 수 있을 것이다.

• 대한한방소아과학회지
• /
• 제18권2호
• /
• pp.21-30
• /
• 2004

Objectives : The purpose of this study is case report of stroke in childhood. The childhood cerebrovascular diseases are interesting than those seen in adulthood, because the etiology and prognosis of the disease in children are quite different from those of adults. Cerebrovascular diseases in children is more common than once recognized. However, relatively little attention has been paid to the epidemiology of childhood stroke. Methods : We experienced one case of ischemic stroke in childhood whose symptoms are similar to that of adults. There is no evidence of cerebrovascular malformation at MRI, MRA film. The cause of stroke is undetermined and just we can see the little infarction lesion on Lt. pons. We treated the patient with herb medicine, acupuncture-Tx, negative-Tx, moxa-Tx and physical treatment. Results : After the treatment of oriental medicine, the patient recovered from the stroke symptoms. Conclusion : we thought that the more follow-up is needed. So we repoert one case of cerebral infarction in children that recovered from stroke symptoms after the treatment of oriental medicine.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제25권3호
• /
• pp.180-193
• /
• 2022

Pediatric inflammatory bowel disease (PIBD) is a multisystem disorder characterized by intestinal and extraintestinal manifestations and complications. Cerebrovascular events (CVE) are rare extraintestinal complications in patients with PIBD. Statistics show that 3.3% patients with PIBD and 1.3-6.4% adult patients with inflammatory bowel disease (IBD) experience CVE during the course of the disease. Therefore, this study aimed to review the records of children with IBD who developed CVE during the course of the disease. We retrospectively reviewed 62 cases of PIBD complicated by CVE. The mean patient age at the time of thrombotic events was 12.48±4.13 years. The incidence of ulcerative colitis was significantly higher than that of Crohn's disease (43 [70.5%] vs. 13 [21.3%] patients). Most patients (87.93%) were in the active phase of IBD at the time of CVE. The mean time interval between the onset of IBD and CVE was 20.84 weeks. Overall, 11 (26.83%) patients showed neurological symptoms of CVE at disease onset. The most frequent symptom on admission was persistent and severe headaches (67.85%). The most common site of cerebral venous thrombosis was the transverse sinuses (n=23, 53.48%). The right middle cerebral artery (n=3, 33.34%) was the predominant site of cerebral arterial infarction. Overall, 41 (69.49%) patients who were mostly administered unfractionated heparin or low-molecular-weight heparin (56.09%) recovered completely. Patients with IBD are at a risk of thromboembolism. CVE may be the most common type of thromboembolism. Based on these findings, the most common risk factor for CVE is IBD flares. In patients with CVE, anticoagulant therapy with heparin, followed by warfarin, is necessary.

• 대한한의학원전학회지
• /
• 제34권1호
• /
• pp.89-102
• /
• 2021

Objectives : This paper aims to examine situations that were conceived as incurable at the time of publication of the 『Huangdineijing』. Methods : The texts of the 『Huangdineijing』 were searched for contents which included 'cannot be cured.' Next, the verses were examined within their context, after which those that specifically indicated 'incurability' were selected. These were categorized according to content, then organized to better show the situations that were seen as incurable to the authors of the 『Huangdineijing』. Results : The conditions deemed incurable in the 『Huangdineijing』 were bloody and purulent stool, ascites, tumors, some purulent inflammation, some infectious diseases with fever, wasting thirst, chronic kidney disorder, some diseases of the connective tissue, epilepsy, cardiac infarction, and cerebrovascular diseases. Internal damage due to acupuncture and poor patient attitude could also contribute to incurability. Conclusions : The authors of the 『Huangdineijing』 were unable to cure some conditions that are currently being cured by Korean Medicine.

• 지역사회간호학회지
• /
• 제6권2호
• /
• pp.212-233
• /
• 1995

Cerebrovascular diseases in Korea is an important health problem since mortality and mobidity have been increasing rapidly. Cerebrovascular diseases marked the 2nd rank of cause specific death rate in 1993. The ploblem of emotion after a stroke has received very little attention from the nursing profession until recently. Even the frequency of the emotional disorder after stroke is uncertain, and there has been very little research. Emotional disorder after stroke was related to limited social function, guilty conscience, helplessness, hopelessness, powerlessness, alienation, and damage of self-image. In the stroke patient, hope may be related to a rehabilitation or enhancing physical condition. Inspiring hope is necessary when stroke patients are unable to mobilize energy on their own behalf and perceive limited or no person choices available. Inspiring hope is an intervention that can be used with many nursing diagnoses, especially when feelings of helplessness, hopelessness, powerlessness, and depression are present. The nurse can inspire hope by understanding the hoping process. On the basis of this literature review, the following suggestions are prosed. 1) Qualitative studies on hope have been done to indentify variables that affect maintenance of hope in the chronically ill patients. 2) In the development of an instrument to measure hope, the validity, reliability, and cultural property of the hope have been estabilished.

• 성인간호학회지
• /
• 제29권3호
• /
• pp.256-265
• /
• 2017

Purpose: The aim of this study was to identify levels of health literacy and reported health behaviors among older adults with cardio-cerebrovascular disease residing in rural areas. Methods: A cross-sectional survey was conducted with a convenience sample of 134 older people (mean age=75.5 years, 71.6% Female) registered at seven health centers. The structured questionnaires were used to measure levels of health literacy and health behaviors. Results: The average functional health literacy score was $6.08{\pm}3.04$, and the health behavior score was $62.92{\pm}6.45$. Respectively health behavior was positively associated with health literacy. Education, economic status, number of family members, number of social activities and health literacy were contribution factors explaining 40.64% of the variance in health behavior. Health literacy specifically explained 12.5% of health behavior. Conclusion: These findings suggest that strategies for improving health behaviors and reducing health inequalities may benefit from adopting a stronger focus on health literacy within prevention, patient education, and other public health interventions. Further longitudinal studies are needed to help confirm that improving health literacy in the elderly may be effective in changing health behaviors.

• 한국치위생학회지
• /
• 제16권2호
• /
• pp.155-163
• /
• 2016

The purpose of the review article is to investigate the influence of periodontal diseases on preterm birth(PTB) and low birth weight(LBW). PTB and LBW are the main risk factors of infant mortality and a major public health problem. PTB is defined as delivery at less than 37 weeks and LBW is less than 2,500 grams. Over Approximately 60 percent of perinatal mortality results from PTB or LBW. Although the causes of PTB and LBW are not fully understood, infection is the leading cause of PTB and LBW. Periodontal diseases are serious disease burdens because they are caused by bacterial endotoxin, inflammatory reaction, and cytokine. The periodontal diseases are the predisposing factors of cerebrovascular and cardiovascular diseases including atherosclerosis. Over the past 15 years, previous studies revealed that periodontitis had adverse outcomes including PTB and LBW in pregnancy.

• Journal of Preventive Medicine and Public Health
• /
• 제14권1호
• /
• pp.39-42
• /
• 1981

Recent changes in the cause of death among the Korean population seem to be systematic and significant. Data on cause of death from the medically certified death certificates provide at least four types of evidence: a sudden increase in recent years in the numbers of death due to cerebrovascular disease or circulatory diseases including rheumatic fever and chronic heart diseases and atherosclerosis; increasing steadily in the numbers of death due to malignant neoplasm of various sites, and death due to accident; decreasing steadily in the numbers of death due to communicable diseases or parasite diseases; and a large number of deaths with unspecified symptoms and ill-defined conditions. The lack of complete registration of the deads occurred or the incomplete description on the cause of death reported suggests that statistical information of cause of death from the medically certified death records is meaningful in interpreting changing patterns.