• Title/Summary/Keyword: Centrifugal

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Short-term Mechanical Circulatory Support with a Centrifugal Pump - Results of Peripheral Extracorporeal Membrane Oxygenator According to Clinical Situation

  • Lee, Woo-Surng;Chee, Hyun-Keun;Song, Meong-Gun;Kim, Yo-Han;Shin, Je-Kyoun;Kim, Jun-Seok;Lee, Song-Am;Hwang, Jae-Joon
    • Journal of Chest Surgery
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    • v.44 no.1
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    • pp.9-17
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    • 2011
  • Background: A peripheral extracorporeal membrane oxygenator (p-ECMO) has been developed to support patients who are dying due to a serious cardiopulmonary condition. This analysis was planned to define the clinical situation in which the patient benefits most from a p-ECMO. Material and Methods: Between June 2007 and Aug 2009, a total of 41 adult patients used the p-ECMO. There were 23 males and 18 females (mean age $54.4{\pm}15.1$ years). All patients had very unstable vital signs with hypoxia and complex cardiac problems. We divided the patients into 4 groups. In the first group, a p-ECMO was used as a bridge to cardiac operation. In the second group, patients did not have the opportunity to undergo any cardiac procedures; nevertheless, they were treated with a p-ECMO. In the third group, patients mostly had difficulty in weaning from CPB (cardiopulmonary bypass) after cardiac operation. The fourth group suffered from many complications, such as pneumonia, bleeding, infections, and LV dysfunction with underlying cardiac problems. All cannulations were performed by the Seldinger technique or cutting down the femoral vessel. A long venous cannula of $DLP^{(R)}$ (Medtronic Inc, Minneapolis, MN) or $RMI^{(R)}$ (Edwards Lifesciences LLC, Irvine, CA) was used together with a 17~21 Fr arterial cannula and a 21 Fr venous cannula. As a bypass pump, a Capiox emergency bypass system ($EBS^{(R)}$; Terumo, Tokyo, Japan) was used. We attempted to maintain a flow rate of $2.4{\sim}3.0\;L/min/m^2$ and an activated clotting time (ACT) of around 180 seconds. Results: Nine patients survived by the use of the p-ECMO. Ten patients were weaned from a p-ECMO but they did not survive, and the remainder had no chance to be weaned from the p-ECMO. The best clinical situation to apply the p-ECMO was to use it as a bridge to cardiac operation and for weaning from CPB after cardiac operation. Conclusion: Various clinical results were derived by p-ECMO according to the clinical situation. For the best results, early adoption of the p-ECMO for anatomical correction appears important.

Enhancement of SNUF Active Trailing-edge Flap Blade Mechanism Design (SNUF뒷전 플랩 블레이드 메커니즘의 설계 개선)

  • Natarajan, Balakumaran;Eun, WonJong;Shin, SangJoon
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.23 no.7
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    • pp.645-653
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    • 2013
  • Seoul National University flap(SNUF) blade is a small-scale rotor blade incorporating a small trailing-edge flap control surface driven by piezoelectric actuators at higher harmonics for vibration attenuation. Initially, the blade was designed using two-dimensional cross-section analysis and geometrically exact one-dimensional beam analysis, and its material configuration was finalized. A flap-deflection angle of ${\pm}4^{\circ}$ was established as the criterion for enhanced vibration reduction based on an earlier simulation. The flap-linkage mechanism was designed and static bench tests were conducted for verifying the performance of the flap-actuation mechanism. Different versions of test beds were developed and tested with the designed flap and the selected APA 200M piezoelectric actuators. Through significant improvements, a maximum deflection of ${\pm}3.7^{\circ}$ was achieved. High-frequency experiments were conducted for evaluating the performance, and the transfer function of the test bed was determined experimentally. With the static tests almost complete, the rotor power required for testing the blade in a whirl tower (centrifugal environment) was calculated, and further preparations are underway.

Change in Quality of Mixed Juice of Fruits and Vegetables by Aseptic Treatment and Packing with Nitrogen Gas during Storage (제균처리와 질소가스포장에 따른 혼합과채주스의 저장 중 품질 변화)

  • Kim, Su-Yeun;Yoon, Young-Bean;Choi, Eon-Ho
    • Korean Journal of Food Science and Technology
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    • v.32 no.6
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    • pp.1271-1277
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    • 2000
  • The extracts from tomatoes, apples, carrots, mallows, watercreses+pine needles, Angelica keiskei Koiz, jujubes and lemons were selected and mixed at the ratio of 3 : 3 : 3 : 1/2 : 1/2 : 1/2 : 1/2 : 1/5 on the basis of sensory evaluation. The mixed extracts were divided into three lots and treated as follows. The first lot was heated for 15 sec at $96^{\circ}C$ without centrifugation and filtration, the second filtered through a ultramembrane filter. For the third one, the ultrafiltrate combined with autoclaved retentates on the membrane filter and the previous centrifugal precipitation. The mixed juices were stored in the glass bottles with atmosphere or in film package with nitrogen gas. And then they were stored at $4^{\circ}$ and $20^{\circ}C$. During storage the treated juices showed $pH\;4.07{\sim}4.10$, titratable acidity $66.35{\sim}84.08$, soluble solid $7{\sim}9^{\circ}Brix$, reducing sugar $5.42{\sim}6.97%$, glucose $1.96{\sim}2.30%$ and fructose $3.46{\sim}4.14%$. The ultrafiltered juices showed yellow color, different from orange color of other treatment lots. Peroxidase activity and microbial population were inhibited by thermal treatment and ultrafiltration. The browning effects of the mixed juice of fruits and vegetables during storage were caused by ascorbic acid oxidation and non-enzymatic browning reaction, which could be reduced by change and packing with nitrogen gas instead of atmosphere inside bottles.

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Quality Characteristics of Makgeolli during Separation Storage Methods (분리저장 방법에 따른 막걸리의 품질특성)

  • Lee, Jin-Won;Park, Jang-Woo
    • Food Engineering Progress
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    • v.14 no.4
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    • pp.346-353
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    • 2010
  • Due to the globalization of Korean foods, there are great interests in traditional Korean foods. Thus, the enhancement and development of makgeolli processing have been constantly accomplished. In case of makgeolli, the storage stability is very important because the fermentation of makgeolli during distribution is still progressed. Therefore, the objective of this study was to investigate storage stability of makgeolli by separation storage methods. During the 30-day storage at $10^{\circ}C$, pH value, titratable acidity, color value, sugar content, reducing sugar content, and alcohol content were measured. Microbial cell counts were also evaluated. Reducing sugar content was decreased after 10 days for all the samples. In the case of titratable acidity and color, these values were constantly increased with storage time. Especially, the yellowness value of the precipitate of makgeolli was increased by two times than that of the beginning. There was a decreasing tendency for lactic acid bacteria with storage time. In case of yeast, there was a decreasing tendency after 15 days, but the significance was not detected. The quality changes in the samples from centrifugal separation were relatively less than the control. Therefore, the separation storage method could affect the enhancement of makgeolli quality during distribution.

Verification of the Numerical Analysis on Caisson Quay Wall Behavior Under Seismic Loading Using Centrifuge Test (원심모형시험을 이용한 케이슨 안벽의 지진시 거동에 대한 수치해석 검증)

  • Lee, Jin-Sun;Park, Tae-Jung;Lee, Moon-Gyo;Kim, Dong-Soo
    • Journal of the Korean Geotechnical Society
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    • v.34 no.11
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    • pp.57-70
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    • 2018
  • In this study, verification of the nonlinear effective stress analysis is performed for introducing performance based earthquake resistance design of port and harbor structures. Seismic response of gravitational caisson quay wall in numerical analysis is compared directly with dynamic centrifuge test results in prototype scale. Inside of the rigid box, model of the gravitational quay wall is placed above the saturated sand layer which can show the increase of excess pore water pressure. The model represents caisson quay wall with a height of 10 m, width of 6 m under centrifugal acceleration of 60 g. The numerical model is made in the same dimension with the prototype scale of the test in two dimensional plane strain condition. Byrne's liquefaction model is adopted together with a nonlinear constitutive model. Interface element is used for sliding and tensional separation between quay wall and the adjacent soils. Verification results show good agreement for permanent displacement of the quay wall, horizontal acceleration at quay wall and soil layer, and excess pore water pressure increment beneath the quay wall foundation.

Superelevation and Bed Variation Due to Attack Angle of Submerged Vanes in Curved Channel (수제 입사각에 따른 개수로 만곡부의 편수위와 하상변동)

  • Park, Sang Deog;Paik, Joongcheol;Jeon, Woo Sung;Lee, Hyun Jae
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.39 no.2
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    • pp.297-306
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    • 2019
  • Since the centrifugal force acts on the flow in the curved channel, a transverse water surface gradient occurs and the thalweg is biased toward the outer bank. The submerged vanes may be used to solve various engineering problems of the curved channels. In order to analyze the influence of an attack angle and the distance between the vane arrays on the river bed variation and the superelevation in a bend, movable bed hydraulic experiments were conducted in a $90^{\circ}$ curved rectangular channel of a small-size gravel bed. Installing the submerged vanes in the bend increases the maximum scour depth. But if vanes are installed in a uniform obtuse angle, the scour depth may be reduced. If the flow rate in the channel bend with vanes equals to the channel forming discharge, the location of the maximum scour depth moved to the downstream and the superelevation increased. However if the flow rate is smaller than that, the location of the maximum scour depth moved upstream and the superelevation decreased. The channel bed change and the superelevation due to the installation of the submerged vanes have been dependent on the interaction of the attack angle, the flow rate, and the distance between the arrays.

Centrifugal Test on Behavior of the Dolphin Structure under Ship Collision (선박충돌 시 돌핀 구조물의 거동에 대한 원심모형실험)

  • Oh, SeungTak;Bae, WooSeok;Cho, SungMin;Heo, Yol
    • Journal of the Korean GEO-environmental Society
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    • v.12 no.1
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    • pp.61-70
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    • 2011
  • The impact protection system consists of an arrangement of circular sheet pile cofferdams-denoted dolphin structuredeeply embedded in the seabed, filled with crushed rock and closed at the top with a robust concrete cap. Centrifuge model tests were performed to investigation the behaviors of dolphins in this study. Total 7 quasi-model tests and 11 dynamic model tests were performed. The main experimental results can be summarized as follows. Firstly, The experimental force-displacement results for quasi-static tests show a limited influence on the initial stiffness of the structure from the change in fill density and the related change in the stiffness of the fill. And by comparing the dissipation at the same dolphin displacement it was found that the denser fill increase the dissipation by 16% for the 20m dolphin and by 23% for the 30m dolphin. The larger sensitivity for the large dolphin is explained by a larger contribution to the dissipation from strain in the fill. In low level impacts the dynamic force-response is up to 26~58% larger than the quasi-static and the dissipation response is showed larger in small displacement. Hence, it is concluded conservative to use the quasi-static response characteristics in the approximation of the response, and it is further concluded that the dolphin resistance to low level impacts is demonstrated to be equivalent and even superior to the high level impacts.

Phytochemical analysis of Panax species: a review

  • Yang, Yuangui;Ju, Zhengcai;Yang, Yingbo;Zhang, Yanhai;Yang, Li;Wang, Zhengtao
    • Journal of Ginseng Research
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    • v.45 no.1
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    • pp.1-21
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    • 2021
  • Panax species have gained numerous attentions because of their various biological effects on cardiovascular, kidney, reproductive diseases known for a long time. Recently, advanced analytical methods including thin layer chromatography, high-performance thin layer chromatography, gas chromatography, high-performance liquid chromatography, ultra-high performance liquid chromatography with tandem ultraviolet, diode array detector, evaporative light scattering detector, and mass detector, two-dimensional high-performance liquid chromatography, high speed counter-current chromatography, high speed centrifugal partition chromatography, micellar electrokinetic chromatography, high-performance anion-exchange chromatography, ambient ionization mass spectrometry, molecularly imprinted polymer, enzyme immunoassay, 1H-NMR, and infrared spectroscopy have been used to identify and evaluate chemical constituents in Panax species. Moreover, Soxhlet extraction, heat reflux extraction, ultrasonic extraction, solid phase extraction, microwave-assisted extraction, pressurized liquid extraction, enzyme-assisted extraction, acceleration solvent extraction, matrix solid phase dispersion extraction, and pulsed electric field are discussed. In this review, a total of 219 articles published from 1980 to 2018 are investigated. Panax species including P. notoginseng, P. quinquefolius, sand P. ginseng in the raw and processed forms from different parts, geographical origins, and growing times are studied. Furthermore, the potential biomarkers are screened through the previous articles. It is expected that the review can provide a fundamental for further studies.

A Study on Evaluating Damage to Railway Embankment Caused by Liquefaction Using Dynamic Numerical Analysis (동적수치해석을 이용한 액상화로 인한 철도제방 피해도 평가법 개발 연구)

  • Ha, Ik-Soo
    • Journal of the Korean Geotechnical Society
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    • v.38 no.11
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    • pp.149-161
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    • 2022
  • This study selected the indexes for evaluating the damage of the railway embankments due to liquefaction from the earthquake damage cases of railway embankments. The study correlated the selected indexes and the settlement of the embankment crest from the dynamic numerical analysis. Further, the correlation was used to develop a method for evaluating the liquefaction damage to the railway embankment. The damage cases and damage types were analyzed, and referring to the liquefaction damage assessment method for other structures, the embankment height (H), the non-liquefiable layer thickness (H1), and the liquefaction potential index were selected as indexes for evaluating the damage. The study performed dynamic effective stress analyses on the railway embankment, and the PM4-Sand model was applied as the constitutive liquefaction model for the embankment foundation ground. The model's validity was first verified by comparing it with the existing dynamic centrifugal model test results performed on the railway embankment. Nine sites where the foundation ground can be liquefied were selected from the data of 549 embankments of the Honam High-speed Railway in Korea. Further, dynamic numerical analyses using four seismic waves as input earthquake load were performed for the selected site sections. The numerical analysis results confirmed the correlation between the evaluation indexes and the embankment crest settlement. A method for efficiently evaluating the damage to the embankment due to liquefaction was proposed using the chart obtained from this correlation.

An Analysis for the Effect of ESP/gas Lift Hybrid System on Oil Productivity (전기공저펌프/가스리프트 혼합시스템이 오일 생산성에 미치는 영향 분석)

  • Lee, Hyesoo;Iranzi, Joseph;Wang, Jihoon;Son, Hanam
    • Journal of the Korean Institute of Gas
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    • v.26 no.5
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    • pp.1-9
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    • 2022
  • Selection of a suitable artificial lift is important in terms of efficient operation and economics for oil production. In general, process of well design includes the selection of artificial lift, but the oil recovery could be enhanced by use of hybrid system combined with two types of artificial lift method according to reservoir condition for oil production. Electric submersible pump (ESP), as a presentative artificial lift method, is a manner for supplying the pressure in the lower part of oil well by using of a multi-stage centrifugal pump with an electric energy. However, there is a disadvantage that has a limit to the application period because of mechanical defection on ESP. Accordingly, it is possible to reduce the shutdown time of production well by applying the ESP/Gas lift hybrid system, which is to switch to a gas lift when an ESP is defective. This study describes the effect of ESP/gas lift hybrid system compared with ESP method for a onshore horizontal well locating in the of Permian basin, USA. As a result of study, ESP/gas lift hybrid system could make more effective productivity than ESP method. Also, we quantitatively predicted how much economic benefit would be obtained when the hybrid system was applied in the production well.