• 제목/요약/키워드: Center of Excellence

검색결과 398건 처리시간 0.03초

Characteristics of long-range transported PM2.5 at a coastal city using the single particle aerosol mass spectrometry

  • Cai, Qiuliang;Tong, Lei;Zhang, Jingjing;Zheng, Jie;He, Mengmeng;Lin, Jiamei;Chen, Xiaoqiu;Xiao, Hang
    • Environmental Engineering Research
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    • 제24권4호
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    • pp.690-698
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    • 2019
  • Air pollution has attracted ever-increasing attention because of its substantial influence on air quality and human health. To better understand the characteristics of long-range transported pollution, the single particle chemical composition and size were investigated by the single particle aerosol mass spectrometry in Fuzhou, China from 17th to 22nd January, 2016. The results showed that the haze was mainly caused by the transport of cold air mass under higher wind speed (10 m·s-1) from the Yangtze River Delta region to Fuzhou. The number concentration elevated from 1,000 to 4,500 #·h-1, and the composition of mobile source and secondary aerosol increased from 24.3% to 30.9% and from 16.0% to 22.5%, respectively. Then, the haze was eliminated by the clean air mass from the sea as indicated by a sharp decrease of particle number concentration from 4,500 to 1,000 #·h-1. The composition of secondary aerosol and mobile sources decreased from 29.3% to 23.5% and from 30.9% to 23.1%, respectively. The particles with the size ranging from 0.5 to 1.5 ㎛ were mainly in the accumulation mode. The stationary source, mobile source, and secondary aerosol contributed to over 70% of the potential sources. These results will help to understand the physical and chemical characteristics of long- range transported pollutants.

A novel homozygous mutation in SZT2 gene in Saudi family with developmental delay, macrocephaly and epilepsy

  • Naseer, Muhammad Imran;Alwasiyah, Mohammad Khalid;Abdulkareem, Angham Abdulrahman;Bajammal, Rayan Abdullah;Trujillo, Carlos;Abu-Elmagd, Muhammad;Jafri, Mohammad Alam;Chaudhary, Adeel G.;Al-Qahtani, Mohammad H.
    • Genes and Genomics
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    • 제40권11호
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    • pp.1149-1155
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    • 2018
  • Epileptic encephalopathies are genetically heterogeneous disorders which leads to epilepsy and cause neurological disorders. Seizure threshold 2 (SZT2) gene located on chromosome 1p34.2 encodes protein mainly expressed predominantly in the parietal and frontal cortex and dorsal root ganglia in the brain. Previous studies in mice showed that mutation in this gene can confers low seizure threshold, enhance epileptogenesis and in human may leads to facial dysmorphism, intellectual disability, seizure and macrocephaly. Objective of this study was to find out novel gene or novel mutation related to the gene phenotype. We have identified a large consanguineous Saudi family segregating developmental delay, intellectual disability, epilepsy, high forehead and macrocephaly. Exome sequencing was performed in affected siblings of the family to study the novel mutation. Whole exome sequencing data analysis, confirmed by subsequent Sanger sequencing validation study. Our results showed a novel homozygous mutation (c.9368G>A) in a substitution of a conserved glycine residue into a glutamic acid in the exon 67 of SZT2 gene. The mutation was ruled out in 100 unrelated healthy controls. The missense variant has not yet been reported as pathogenic in literature or variant databases. In conclusion, the here detected homozygous SZT2 variant might be the causative mutation that further explain epilepsy and developmental delay in this Saudi family.

커뮤니티 컴퓨팅 보안 (Security for Community Computing)

  • 김순동;심윤주;김현숙;최동순;조위덕
    • 한국정보과학회:학술대회논문집
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    • 한국정보과학회 2006년도 한국컴퓨터종합학술대회 논문집 Vol.33 No.1 (C)
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    • pp.307-309
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    • 2006
  • 유비쿼터스 컴퓨팅 패러다임이 제시된 이래로 세계적으로 유비쿼터스 컴퓨팅에 대한 연구가 활발히 진행되고있다. 그러나 아직까지 유비쿼터스 컴퓨팅은 현실세계에 적용하기에는 많은 기술적. 비기술적 장벽들이 많이 존재한다. 보안과 프라이버시에 관한 사회적인 우려는 유비쿼터스 컴퓨팅 기술의 실제 환경에 적용하는데 큰 걸림돌로 작용한다. 따라서 진행되고 있는 많은 유비쿼터스 연구들은 각각의 프로젝트에 적합한 보안 및 프라이버시 보호를 위한 기술들을 개발하여 적용하고 있는 실정이다. 유비쿼터스 시스템 연구센터는 유비쿼터스 컴퓨팅을 구현하기 위해 커뮤니티 컴퓨팅을 제안하였다. 커뮤니티 컴퓨팅에서 발생할 수 있는 보안 문제점들을 해결하기 위해 커뮤니티 스킨을 구현하였다. 커뮤니티 스킨은 커뮤니티 구성원들을 커뮤니티 외부 개체들과 구분 짓고, 외부의 침입으로부터 보호해 줄 수 있다. 커뮤니티 스킨은 암호학적 알고리즘을 적용함으로써 구현될 수 있다. 본고에서는 보안 서비스를 4가지 유형으로 분류하고 이를 토대로 커뮤니티가 보안 협약을 통한 커뮤니티 스킨을 형성 하도록 하였다.

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