• 제목/요약/키워드: Cellular characteristics

검색결과 726건 처리시간 0.028초

ARCA-An Adaptive Routing Protocol for Converged Ad-Hoc and Cellular Networks

  • Wu, Yumin;Yang, Kun;Chen, Hsiao-Hwa
    • Journal of Communications and Networks
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    • 제8권4호
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    • pp.422-431
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    • 2006
  • This paper proposes an adaptive routing protocol called ARCA for converged ad-hoc and cellular network (CACN). Due to the limitation of both bandwidth and transmission range in a cell, a mobile host (MH) may not be able to make a call during busy time. CACN offers a flexible traffic diversion mechanism that allows a MH to use the bandwidth in another cell to ease the congestion problem and increase the throughput in a cellular network. Based on the presentation of CACN's physical characteristics, the paper details the design issues and operation of the adaptive routing protocol for CACN (ARCA). Detailed numerical analysis is presented in terms of both route request rejection rate and routing overhead, which, along with the simulation results, have indicated the effectiveness and efficiency of the ARCA protocol.

복사 열손실에 의한 소염근처에서 셀모양 대향류 확산화염의 특성에 대한 수치해석 (Numerical Analysis of Characteristics of Cellular Counterflow Diffusion Flames near Radiative Extinction Limit)

  • 이수룡
    • 대한기계학회논문집B
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    • 제38권6호
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    • pp.493-500
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    • 2014
  • Damk$\ddot{o}$hler수가 클 때 복사열손실에 의한 소염근처에서 셀모양의 대향류확산화염의 특성에 대하여 수치해석적으로 연구하였다. Lewis 수를 0.5로 두고 일차원 정상상태의 화염의 해에 매우 작은 교란을 가하여 시간에 따른 화염전개를 계산하였다. 천이과정 초기에는 선형안정성 해석에서 예측된 결과와 매우 비슷하게 진행된다. 시간이 증가함에 따라 증가율이 가장 강한 파동수를 갖는 교란파가 성장하고, 완전히 발달되면 소염영역과 화염영역이 번갈아 나타나는 셀모양의 화염구조를 갖는다. 화염온도는 총엔탈피의 국소 이득 때문에 일차원 정상상태의 화염온도보다 높다. 셀모양의 확산화염은 Damk$\ddot{o}$hler 수가 증가함에 따라 셀의 모양이 원형으로 되며 일차원 정상상태 소염조건보다 큰 Damk$\ddot{o}$hler 수에서도 셀모양의 화염은 꺼지지 않고 살아남는다.

Wettability and cellular response of UV light irradiated anodized titanium surface

  • Park, Kyou-Hwa;Koak, Jai-Young;Kim, Seong-Kyun;Heo, Seong-Joo
    • The Journal of Advanced Prosthodontics
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    • 제3권2호
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    • pp.63-68
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    • 2011
  • PURPOSE. The object of this study was to investigate the effect of UV irradiation (by a general commercial UV sterilizer) on anodized titanium surface. Surface characteristics and cellular responses were compared between anodized titanium discs and UV irradiated anodized titanium discs. MATERIALS AND METHODS. Titanium discs were anodized and divided into the following groups: Group 1, anodized (control), and Goup 2, anodized and UV irradiated for 24 hours. The surface characteristics including contact angle, roughness, phase of oxide layer, and chemical elemental composition were inspected. The osteoblast-like human osteogenic sarcoma (HOS) cells were cultured on control and test group discs. Initial cellular attachment, MTS-based cell proliferation assay, and ALP synthesis level were compared between the two groups for the evaluation of cellular response. RESULTS. After UV irradiation, the contact angle decreased significantly (P<.001). The surface roughness and phase of oxide layer did not show definite changes, but carbon showed a considerable decrease after UV irradiation. Initial cell attachment was increased in test group (P=.004). Cells cultured on test group samples proliferated more actively (P=.009 at day 2, 5, and 7) and the ALP synthesis also increased in cells cultured on the test group (P=.016 at day 3, P=.009 at day 7 and 14). CONCLUSION. UV irradiation induced enhanced wettability, and increased initial cellular responses of HOS cells on anodized titanium surface.

Oligomeric Structures Determine the Biochemical Characteristics of Human Nucleoside Diphosphate Kinases

  • Kim, Sun-Young;Song, Eun-Joo;Chang, Keun-Hye;Kim, Eun-Hee;Chae, Suhn-Kee;Lee, Han-Soo;Lee, Kong-Joo
    • BMB Reports
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    • 제34권4호
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    • pp.355-364
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    • 2001
  • Major human Nucleoside diphosphate kinases (NDPKs) exist as hetero-oligomers, consisting of NDPK-A and NDPK-B, rather than homo-oligomer. To investigate their biological function depending on the oligomeric structure in vivo, we characterized the biochemical properties of cellular NDPK. Cellular NDPKs, which are made up of a unique combination of isoforms, were purified from human erythrocyte and placenta. We found that cellular NDPK and recombinant isoforms NDPKs have their own distinct biochemical properties in autophosphorylation, stability toward heat or urea, and DNA binding. Cellular NDPK was found to have unique characteristics rather than the expected additive properties of recombinant isoforms. The mutations in the dimeric interface of NDPK-B (R34G, N69H or K135L) caused defective DNA binding and simultaneously reduced the enzymatic stability These results suggest that the oligomeric interaction could play a major role in the stability of catalytic domain and might be related to the regulation of various cellular functions of NDPK.

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Perceptional Change of a New Product, DMB Phone

  • Kim, Ju-Young;Ko, Deok-Im
    • 마케팅과학연구
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    • 제18권3호
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    • pp.59-88
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    • 2008
  • Digital Convergence means integration between industry, technology, and contents, and in marketing, it usually comes with creation of new types of product and service under the base of digital technology as digitalization progress in electro-communication industries including telecommunication, home appliance, and computer industries. One can see digital convergence not only in instruments such as PC, AV appliances, cellular phone, but also in contents, network, service that are required in production, modification, distribution, re-production of information. Convergence in contents started around 1990. Convergence in network and service begins as broadcasting and telecommunication integrates and DMB(digital multimedia broadcasting), born in May, 2005 is the symbolic icon in this trend. There are some positive and negative expectations about DMB. The reason why two opposite expectations exist is that DMB does not come out from customer's need but from technology development. Therefore, customers might have hard time to interpret the real meaning of DMB. Time is quite critical to a high tech product, like DMB because another product with same function from different technology can replace the existing product within short period of time. If DMB does not positioning well to customer's mind quickly, another products like Wibro, IPTV, or HSPDA could replace it before it even spreads out. Therefore, positioning strategy is critical for success of DMB product. To make correct positioning strategy, one needs to understand how consumer interprets DMB and how consumer's interpretation can be changed via communication strategy. In this study, we try to investigate how consumer perceives a new product, like DMB and how AD strategy change consumer's perception. More specifically, the paper segment consumers into sub-groups based on their DMB perceptions and compare their characteristics in order to understand how they perceive DMB. And, expose them different printed ADs that have messages guiding consumer think DMB in specific ways, either cellular phone or personal TV. Research Question 1: Segment consumers according to perceptions about DMB and compare characteristics of segmentations. Research Question 2: Compare perceptions about DMB after AD that induces categorization of DMB in direction for each segment. If one understand and predict a direction in which consumer perceive a new product, firm can select target customers easily. We segment consumers according to their perception and analyze characteristics in order to find some variables that can influence perceptions, like prior experience, usage, or habit. And then, marketing people can use this variables to identify target customers and predict their perceptions. If one knows how customer's perception is changed via AD message, communication strategy could be constructed properly. Specially, information from segmented customers helps to develop efficient AD strategy for segment who has prior perception. Research framework consists of two measurements and one treatment, O1 X O2. First observation is for collecting information about consumer's perception and their characteristics. Based on first observation, the paper segment consumers into two groups, one group perceives DMB similar to Cellular phone and the other group perceives DMB similar to TV. And compare characteristics of two segments in order to find reason why they perceive DMB differently. Next, we expose two kinds of AD to subjects. One AD describes DMB as Cellular phone and the other Ad describes DMB as personal TV. When two ADs are exposed to subjects, consumers don't know their prior perception of DMB, in other words, which subject belongs 'similar-to-Cellular phone' segment or 'similar-to-TV' segment? However, we analyze the AD's effect differently for each segment. In research design, final observation is for investigating AD effect. Perception before AD is compared with perception after AD. Comparisons are made for each segment and for each AD. For the segment who perceives DMB similar to TV, AD that describes DMB as cellular phone could change the prior perception. And AD that describes DMB as personal TV, could enforce the prior perception. For data collection, subjects are selected from undergraduate students because they have basic knowledge about most digital equipments and have open attitude about a new product and media. Total number of subjects is 240. In order to measure perception about DMB, we use indirect measurement, comparison with other similar digital products. To select similar digital products, we pre-survey students and then finally select PDA, Car-TV, Cellular Phone, MP3 player, TV, and PSP. Quasi experiment is done at several classes under instructor's allowance. After brief introduction, prior knowledge, awareness, and usage about DMB as well as other digital instruments is asked and their similarities and perceived characteristics are measured. And then, two kinds of manipulated color-printed AD are distributed and similarities and perceived characteristics for DMB are re-measured. Finally purchase intension, AD attitude, manipulation check, and demographic variables are asked. Subjects are given small gift for participation. Stimuli are color-printed advertising. Their actual size is A4 and made after several pre-test from AD professionals and students. As results, consumers are segmented into two subgroups based on their perceptions of DMB. Similarity measure between DMB and cellular phone and similarity measure between DMB and TV are used to classify consumers. If subject whose first measure is less than the second measure, she is classified into segment A and segment A is characterized as they perceive DMB like TV. Otherwise, they are classified as segment B, who perceives DMB like cellular phone. Discriminant analysis on these groups with their characteristics of usage and attitude shows that Segment A knows much about DMB and uses a lot of digital instrument. Segment B, who thinks DMB as cellular phone doesn't know well about DMB and not familiar with other digital instruments. So, consumers with higher knowledge perceive DMB similar to TV because launching DMB advertising lead consumer think DMB as TV. Consumers with less interest on digital products don't know well about DMB AD and then think DMB as cellular phone. In order to investigate perceptions of DMB as well as other digital instruments, we apply Proxscal analysis, Multidimensional Scaling technique at SPSS statistical package. At first step, subjects are presented 21 pairs of 7 digital instruments and evaluate similarity judgments on 7 point scale. And for each segment, their similarity judgments are averaged and similarity matrix is made. Secondly, Proxscal analysis of segment A and B are done. At third stage, get similarity judgment between DMB and other digital instruments after AD exposure. Lastly, similarity judgments of group A-1, A-2, B-1, and B-2 are named as 'after DMB' and put them into matrix made at the first stage. Then apply Proxscal analysis on these matrixes and check the positional difference of DMB and after DMB. The results show that map of segment A, who perceives DMB similar as TV, shows that DMB position closer to TV than to Cellular phone as expected. Map of segment B, who perceive DMB similar as cellular phone shows that DMB position closer to Cellular phone than to TV as expected. Stress value and R-square is acceptable. And, change results after stimuli, manipulated Advertising show that AD makes DMB perception bent toward Cellular phone when Cellular phone-like AD is exposed, and that DMB positioning move towards Car-TV which is more personalized one when TV-like AD is exposed. It is true for both segment, A and B, consistently. Furthermore, the paper apply correspondence analysis to the same data and find almost the same results. The paper answers two main research questions. The first one is that perception about a new product is made mainly from prior experience. And the second one is that AD is effective in changing and enforcing perception. In addition to above, we extend perception change to purchase intention. Purchase intention is high when AD enforces original perception. AD that shows DMB like TV makes worst intention. This paper has limitations and issues to be pursed in near future. Methodologically, current methodology can't provide statistical test on the perceptual change, since classical MDS models, like Proxscal and correspondence analysis are not probability models. So, a new probability MDS model for testing hypothesis about configuration needs to be developed. Next, advertising message needs to be developed more rigorously from theoretical and managerial perspective. Also experimental procedure could be improved for more realistic data collection. For example, web-based experiment and real product stimuli and multimedia presentation could be employed. Or, one can display products together in simulated shop. In addition, demand and social desirability threats of internal validity could influence on the results. In order to handle the threats, results of the model-intended advertising and other "pseudo" advertising could be compared. Furthermore, one can try various level of innovativeness in order to check whether it make any different results (cf. Moon 2006). In addition, if one can create hypothetical product that is really innovative and new for research, it helps to make a vacant impression status and then to study how to form impression in more rigorous way.

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에너지원에 따른 이동전화기 배터리의 소손패턴 해석에 관한 연구 (Study on the Analysis of Damage Patterns of Cellular Phone Batteries According to Energy Sources)

  • 최충석
    • 한국화재소방학회논문지
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    • 제25권6호
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    • pp.21-26
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    • 2011
  • 본 논문에서는 에너지원에 따른 이동전화기(SCH_W830) 배터리의 소손 패턴을 제시함으로써 소비자분쟁 해결의 자료로 활용하고자 한다. 실험이 진행될 때의 주위 온도는 $22{\pm}2^{\circ}C$, 습도는 40~60 %를 유지함으로써 신뢰성을 확보하였다. 실험에 사용된 이동전화기의 배터리 전압은 양극(+)과 음극 (1)(-) 사이의 전압은 4.19 V이며, 양극(+)과 음극 (2)(-) 사이의 전압은 4.18 V로 측정되었다. 일반화염 인가에 의한 이동 전화기의 난연성 시험은 한국산업규격(KS)을 적용하였으며, 일반화염이 30 sec 동안 외함에 인가되어도 내장된 배터리의 소손은 없는 것으로 확인되었다. 생리 식염수(NaCl, 0.9%)에 이동전화기를 180 sec 침수시킨 결과 배터리 단자 사이에 누설전류에 의한 발열로 탄화 및 용융이 발생한 흔적을 확인할 수 있었다. 전자레인지(MWO)를 이용하여 70 sec 동안 이동전화기를 가열하면 금속홀더, 충전용 커넥터, 안테나 등이 내장된 부분에서 용융 및 변색이 확인되며, 그 밖의 부분은 특이사항이 없는 것을 알 수 있다. 즉, 인가된 에너지원의 종류에 따라 이동전화기 외형의 탄화, 내장된 금속 및 유전체, 배터리 단자대의 손상 및 변형 등이 다르게 발생하지만 전압은 비교적 일정한 특성을 보이는 것으로 보아 연소의 확산 패턴, 금속의 용융 및 변형 부분의 특성을 종합적으로 고려하여 해석하면 소손 원인 판정이 가능하다.

Morphogenetic and neuronal characterization of human neuroblastoma multicellular spheroids cultured under undifferentiated and all-trans-retinoic acid-differentiated conditions

  • Jung, Gwon-Soo;Lee, Kyeong-Min;Park, Jin-Kyu;Choi, Seong-Kyoon;Jeon, Won Bae
    • BMB Reports
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    • 제46권5호
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    • pp.276-281
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    • 2013
  • In this study, we aimed to compare the morphogenetic and neuronal characteristics between monolayer cells and spheroids. For this purpose, we established spheroid formation by growing SH-SY5Y cells on the hydrophobic surfaces of thermally-collapsed elastin-like polypeptide. After 4 days of culture, the relative proliferation of the cells within spheroids was approximately 92% of the values for monolayer cultures. As measured by quantitative assays for mRNA and protein expressions, the production of synaptophysin and neuronspecific enolase (NSE) as well as the contents of cell adhesion molecules (CAMs) and extracellular matrix (ECM) proteins are much higher in spheroids than in monolayer cells. Under the all-trans-retinoic acid (RA)-induced differentiation condition, spheroids extended neurites and further up-regulated the expression of synaptophysin, NSE, CAMs, and ECM proteins. Our data indicate that RA-differentiated SH-SY5Y neurospheroids are functionally matured neuronal architectures.

Effects of 5-Aza-2'-Deoxycytidine, Bromodeoxyuridine, Interferons and Hydrogen Peroxide on Cellular Senescence in Cholangiocarcinoma Cells

  • Moolmuang, Benchamart;Singhirunnusorn, Pattama;Ruchirawat, Mathuros
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권3호
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    • pp.957-963
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    • 2016
  • Cellular senescence, a barrier to tumorigenesis, controls aberrant proliferation of cells. We here aimed to investigate cellular senescence in immortalized cholangiocyte and cholangiocarcinoma cell lines using five different inducing agents: 5-aza-2'deoxycytidine, bromodeoxyuridine, interferons ($IFN{\beta}$ and $IFN{\gamma}$), and hydrogen peroxide. We analyzed senescence characteristics, colony formation ability, expression of genes involved in cell cycling and interferon signaling pathways, and protein levels. Treatment with all five agents decreased cell proliferation and induced cellular senescence in immortalized cholangiocyte and cholangiocarcinoma cell lines with different degrees of growth-inhibitory effects depending on cell type and origin. Bromodeoxyuridine gave the strongest stimulus to inhibit growth and induce senescence in most cell lines tested. Expression of p21 and interferon related genes was upregulated in most conditions. The fact that bromodeoxyuridine had the strongest effects on growth inhibition and senescence induction implies that senescence in cholangiocarcinoma cells is likely controlled by DNA damage response pathways relating to the p53/p21 signaling. In addition, interferon signaling pathways may partly regulate this mechanism in cholangiocarcinoma cells.

Bacillus thuringiensis subsp. israelensis 균주의 Hemolysin 성질 (Characteristics of Hemolysin from Bacillus thuringiensis subsp. israelensis)

  • 황지연;김광현
    • 한국미생물·생명공학회지
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    • 제15권6호
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    • pp.425-429
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    • 1987
  • B. thuringiensis subsp. israelensis 균주가 생성하는 $\delta$-endotoxin의 alkali 용해에서 생성되는 hemolysin fragment 와 extra-cellular hemolysin 의 상관관계를 조사하기 위한 기초자료로서 extra-cellular hemolysin을 분리 정제하여 그 성질을 조사하였다. 균체 배양액에 유안을 염석 및 투석시킨 후, Sephadex G-200 gel filtration 과 DEAE-cellulose column chromatography를 행하여 균체외 homely-sin을 정제하였다. 정제된 extra-cellular hemolysin 은 SDS-polyacrylamide gel 전기영동에서 47,000 dalton의 분자량을 가진 단일 단백질 band를 얻었다. 또한 정제된 hemolysin은 thiol agents에 의해 그 활성이 증가되었으나, cholesterol 및 protease 처리 또는 금속이온 즉, FeSO$_4$나 CuSO$_4$에 의해 그 활성 이 감소되었다.

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GF($2^m$)상의 셀룰라 오토마타를 이용한 VLSI 구조 (Cellular Automata based on VLSI architecture over GF($2^m$))

  • 전준철;김현성;이형목;유기영
    • 정보보호학회논문지
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    • 제12권3호
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    • pp.87-94
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    • 2002
  • 본 논문에서는 GF($2^m$)상에서 새로운 MSB 우선 곱셈 알고리즘을 제안하고, 셀룰라 오토마타(Cellular Automata, CA) 를 기반으로 한 곱셈기를 설계한다. 본 논문에서 제안한 곱셈기는 PBCA(Periodic Boundary CA)의 특성을 AOP(All One Polynomial)의 특성과 조화시킴으로써 기존의 구조에 비하여 정규성을 높이고 지연 시간을 줄일 수 있는 구조이다. 제안된 곱셈기는 공개키 암호화의 핵심이 되는 지수기의 구현을 위한 효율적인 기본구조로 사용될 것으로 기대된다.