• Title/Summary/Keyword: Cell-to-Cell Deviation

검색결과 197건 처리시간 0.028초

Effects of Didecyldimethylammonium Chloride on Sprague-Dawley Rats after Two Weeks of Inhalation Exposure

  • Lim, Cheol-Hong;Chung, Yong-Hyun
    • Toxicological Research
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    • 제30권3호
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    • pp.205-210
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    • 2014
  • Didecyldimethylammonium chloride (DDAC) is used for various purposes, such as a fungicide for coolants, an antiseptic for wood, and disinfectant for cleaning. Despite the increasing likelihood of DDAC inhalation, available data on its toxicity from inhalation are scarce. Therefore, this study was aimed at confirming the toxicity of DDAC after inhalation exposure for 2 wk. Male Sprague-Dawley rats were exposed to approximately $0.15mg/m^3$, $0.6mg/m^3$, and $3.6mg/m^3$ DDAC aerosols in whole-body exposure chambers. After DDAC exposure for 2 wk, effects of DDAC on body weight, blood, bronchoalveolar lavage (BAL), and the lungs were verified. The mass median aerodynamic diameter of DDAC aerosols was $1.86{\mu}m$ and the geometric standard deviation was 2.75. The concentrations of DDAC aerosols for the low, medium, and high groups were $0.15{\pm}0.15mg/m^3$, $0.58{\pm}0.40mg/m^3$, and $3.63{\pm}1.56mg/m^3$, respectively. Body weight gain was significantly influenced by DDAC exposure. In the high group, a body weight decrease of 2.6 g was observed, whereas a 25.8 g increase was observed in the normal control group after the first 3 days. The low and medium groups showed 23.3 g and 20.4 g increases, respectively, after the first 3 days. Decreases in body weight were recovered during the next 4 days. In contrast, no changes were noted in hematological and blood biochemistry parameters after DDAC exposure. Furthermore, only mild effects were observed on bronchoalveolar cell differentiation counts and cell damage parameters in the BAL fluids of the medium and high groups. Although inflammatory cell infiltration and interstitial pneumonia were partially observed, fibrosis was not found in the lungs of the medium and high groups. In conclusion, body weight gain and the lungs were mainly affected by DDAC exposure. The no-observed-adverse-effect level (NOAEL) for DDAC was determined as $0.15mg/m^3$.

측면시야각에서의 대칭적 명암대비비 향상을 위한 IPS-LCD 광학보상 (Optical Compensation of IPS-LCD for Symmetric-High-Contrast at Off-Axis Oblique View)

  • 김태현;김봉식;박우상
    • 한국전기전자재료학회논문지
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    • 제29권3호
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    • pp.175-180
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    • 2016
  • In this study, we proposed an optical compensation method to improve the symmetricity of contrast ratio for wide viewing angle IPS (in-plane switching) LCD. First, the phase retardation depending on the thickness of compensation film is calculated, and then the phase change is presented at the $Poincar{\acute{e}}$ sphere. The phase retardation and the polarization state of the light passing through the optical elements are caculated by using the EJMM (extended Jones matrix method). In addition, the transmittance and the contrast countour are also calculated by using the Berremann's $4{\times}4$ matrix method. The simulation is carried out for a IPS LC cell with positive A/C/A compensation film. From the standard deviation of the contrast ratio, we confirmed the symmetricity at each viewing angle is inversely proportional to the standard deviation and calculated the optimum design condition of the uniaxial compensation film for the IPS LCD.

차세대 리튬 금속 전지 연구 및 개발을 위한 코인형 전지의 효율적 설계 (A Rational Design of Coin-type Lithium-metal Full Cell for Academic Research)

  • 이민규;이동현;한재웅;정진오;최현빈;이현태;임민홍;이홍경
    • 전기화학회지
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    • 제24권3호
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    • pp.65-75
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    • 2021
  • 코인형 전지는 리튬 이차 전지 연구의 주요 평가 플랫폼으로써 새로운 소재 및 개념을 발굴하고 차세대 전지의 기초 연구에도 큰 기여를 하고 있다. 리튬 금속 전지는 500 Wh kg-1 이상의 에너지 밀도를 구현할 수 있어 유망한 차세대 리튬 이차 전지 후보군으로 고려되고 있으나, 덴드라이트 형태의 리튬 전착과 함께 극심한 부피 변화 및 표면적 증가라는 성능 열화에 매우 취약하다. 특히, 리튬 금속 전지의 수명은 전해질 양, 리튬 두께, 내부 압력 등과 같은 전지 설계 및 구조에 매우 의존하기 때문에 코인셀 수준에서의 성능 평가 및 신뢰성에 치명적이다. 따라서, 기존 코인셀 구조를 개선한 리튬 금속 음극 특화 전지 설계 및 규격화가 요구된다. 본 연구에서는 상용수준에서의 주요 전지 설계 인자인 극소량의 전해질과 높은 양극 로딩 레벨, 박막 리튬 사용 등의 환경에서 성능 및 재현성을 확보한 코인셀 구조를 제안한다. 양극과 음극의 면적비를 1에 근접하게 제어하여 비활성 공간을 최소화하고 용량 저하현상을 완화시켰다. 또한, 코인셀 내 압력을 정량화하여 압력의 균일성이 중요한 인자임을 규명하고 유연성 고분자 (PDMS) 필름 도입과 내부 부품의 변화를 통해 기존보다 높고 (0.6 MPa → 2.13 MPa) 균일한 압력(표준편차: 0.43 → 0.16)이 가하도록 개조하였다. 이를 통해 최적의 설계를 정립을 통해 기존보다 향상된 재현성을 확인하였다.

Leukocyte adherence inhibition test를 이용한 Mycobacterium 속균(屬菌) 감작(感作)기니픽의 세포면역반응(細胞免疫反應)의 특이성(特異性) (Specificity of cell-mediated immunity in guinea pigs sensitized with Mycobacterium spp using the leukocyte adherence inhibition test)

  • 박성국;전무형;이헌준;민원기;윤용덕
    • 대한수의학회지
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    • 제29권3호
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    • pp.283-289
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    • 1989
  • In order to measure in vitro cell mediated immunity in the guinea pigs sensitized with the killed bacilli of Mycobacterium bovis ($AN_5$), M avium (serotype 2), M tuberculosis and M intracellulare (serotype 8), leukocyte adherence inhibition (LAI) test was established using the antigens of purified protein derivatives (PPD) tuberculin. By using LAI test, specificity of cell-mediated immune responses of the guinea pigs inoculated with various Mycobacterium spp was investigated, and comparison between values of LAI and skin test was also made to evaluate the specificity of the newly designed test. The results obtained throughout the experiments were summarized as follows; 1. The optimal concentration of PPD antigens for LAI test was 1 to 2mg per ml of medium. 2. When the leukocytes of guinea pigs sensitized with both M bovis($AN_5$) and M avium (serotype 2) for 2 to 8 weeks were incubated with homologous or heterologous PPD antigens, mean values of LAI test were $61.2{\pm}11.2$ and $65.6{\pm}5.1%$ in homologous PPD antigens respectively, while $30.0{\pm}3.7$ and $32.8{\pm}5.7%$ in heteNlogous PPD antigens, showing the prominently high value of LAI in the homologous syst,em (p<0.01). 3. When the leukocytes of guinea pigs sensitized with both M tuberculosis and M intracellulare (serotype 8) for 2 to 8 weeks were incubated with homologous and heterologous PPD antigens, mean values of LAI test were $67.9{\pm}2.9$ and $66.9{\pm}5.0%$ in homologous PPD antigens, while $27.4{\pm}7.4$ and $24.4{\pm}7.1%$ in heterologous PPD antigens, showing the prominently high value of LAI in the homologous system (p<0.01). 4. Comparing with the specificity of LAI and skin tests on the basis of the value obtained from the homologous system, deviation of reaction was revealed to be 49.5 to 100.2 in LAI test, and -15.9 to 52.0 in skin test.

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MMAP 이산시간 큐잉 시스템의 속산 시뮬레이션 (An Efficient Simulation of Discrete Time Queueing Systems with Markov-modulated Arrival Processes)

  • 국광호;강성열
    • 한국시뮬레이션학회논문지
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    • 제13권3호
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    • pp.1-10
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    • 2004
  • The cell loss probability required in the ATM network is in the range of 10$^{-9}$ ∼10$^{-12}$ . If Monte Carlo simulation is used to analyze the performance of the ATM node, an enormous amount of computer time is required. To obtain large speed-up factors, importance sampling may be used. Since the Markov-modulated processes have been used to model various high-speed network traffic sources, we consider discrete time single server queueing systems with Markov-modulated arrival processes which can be used to model an ATM node. We apply importance sampling based on the Large Deviation Theory for the performance evaluation of, MMBP/D/1/K, ∑MMBP/D/1/K, and two stage tandem queueing networks with Markov-modulated arrival processes and deterministic service times. The simulation results show that the buffer overflow probabilities obtained by the importance sampling are very close to those obtained by the Monte Carlo simulation and the computer time can be reduced drastically.

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A Novel Anti-Islanding Method for Utility Interconnection of Distributed Power Generation Systems

  • In-Ho
    • KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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    • 제4B권4호
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    • pp.217-224
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    • 2004
  • A novel anti-islanding method for the distributed power generation system (DPGS) is proposed in this paper. Three different islanding scenarios are explored and presented based on the analysis of real and reactive power mismatch. It is shown via investigation that islanding voltage is a function of real power alone, where its frequency is a function of both real and reactive power. Following this analysis, a robust anti-islanding algorithm is developed. The proposed algorithm continuously perturbs ($\pm$5%) the reactive power supplied by the DPGS while simultaneously monitoring the utility voltage and frequency. In the event of islanding, a measurable frequency deviation takes place, upon which the real power of the DPGS is further reduced to 80%. A drop in voltage positively confirms islanding and the DPGS is then safely disconnected. This method of control is shown to be robust: it is able to detect islanding under resonant loads and is also fast acting (operable in one cycle). Possible islanding conditions are simulated and verified through analysis. Experimental results on a 0.5kW fuel cell system connected to a utility grid are discussed.

Chemiluminescence System with Air Pump as a Sensor for Determination of Metal Levels in Rain

  • Hong, Hyuck-Gi;Lim, H.B.
    • Bulletin of the Korean Chemical Society
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    • 제26권12호
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    • pp.1937-1940
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    • 2005
  • A lab-made chemiluminescence system with air pump was developed for monitoring of some metal levels in rain. The air pump enabled injection of 17.7 $\mu$g samples into a glass cell filled with luminol-$H_2O_2$ reagent of typically 300 $\mu$L for chemiluminescence measurement. The monitored trend of total metal ions in the rain collected in our campus was compared with analytical results of each metal ion from GFAAS. The system was also demonstrated to determine $Cr^{6+}$ by reduction to $Cr^{3+}$ using $SnCl_2$. The limit of detection for $Cr^{6+}$ obtained by 4 measurements was 85.0 pg $mL^{-1}$ with a relative standard deviation of 3.4%. Although this system doesn’t have selectivity due to the characteristics of chemiluminescence, application of it to environmental monitoring as a sensor for some transition metal ions was demonstrated.

셀형 유연조립시스템에서 작업부하 균형을 고려한 통합 배치설계에 관한 연구 (A Study on Even Distribution of Workloads Using Simulated Annealing Method on Integrated Layout Design in Cellular flexible Assembly Systems)

  • 정지용;노인규
    • 한국경영과학회지
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    • 제23권4호
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    • pp.63-73
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    • 1998
  • With the success of flexible manufacturing systems(FMSs), flexible assembly systems(FASs) have been developed to automatic factories further. As in a cellular FMS, a celluar FAS is considered as the most flexible and feasible assembly systems configuration. This paper presents a method for the integrated layout design in cellular FASs. Unlike the traditional paper, this paper deals with the formation of cells and the layout of cells for jobs with operation times on different machines. The procedure in this paper consists of two distinct phases. The first phase presents machine arrangement in a double rows flowline. cell formation not to allow intercellular movements, and integrated layout design in cellular FASs considering the characteristics of FAS, layout, and production factors This phase uses older optimal algorithm. The second phase proposes to balance the system with an objective of reducing the degree of workload deviation in the cells. Simulated annealing method is used to balance the system. This phase also shows the integrated layout design in cellular FASs with the cost less than total cost of the first phase.

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가시광선 영역에서의 선면 감지 센서 (Line Edge Detection Sensor using Visual Spectral Wavelength)

  • 최규남
    • 한국전자통신학회논문지
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    • 제7권2호
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    • pp.303-308
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    • 2012
  • 실린더 형태의 롤러에 감기는 원단들의 가장자리에 있는 선 이나 면들을 감지할 수 있는 1차원 선면감지 센서에 대하여 연구하였다. 선면감지 센서는 광학계의 정렬을 필요로 하지 않는 1안 렌즈를 사용한 1:1 광학계를 사용하였고 2분할 실리콘 수광소자를 사용한 두 개 채널로 부터의 차 및 합 신호를 처리하여 구현하였다. 측정된 결과는 다양한 재질 및 색상을 갖는 피사체에 대해서도 0.1mm 까지 선폭을 감지할 수 있었으며 감기는 원단은 0.2mm 편차 이내로 감기는 것을 보여주었다.

Isomorphous Substitution of Fe in Sodalite and Its Electric Characterization

  • Kim, Chy-Hyung;Jung, Chi-Sup
    • Bulletin of the Korean Chemical Society
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    • 제14권2호
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    • pp.215-220
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    • 1993
  • Experiment on isomorphous substitution of Al by Fe in sodalite framework was carried out using dry way method at 800-900$^{\circ}$C in nitrogen atmosphere. The substitution of Fe was possible up to 25 mole% with some deviation of symmetry in sodalite cage. The cubic unit cell parameter increased with increasing Fe content. It showed ionic semiconducting property, especially the highest conductivity and the lowest activation energy in 10 mole% Fe-substituted sodalite which could behave as a superionic conductor at above 400$^{\circ}$C. When more Fe was introduced into sodalite the electronic conductivity was improved at high temperature. But the relative electronic contribution was found to be lower compared with ionic contribution at high temperature. In infrared spectra some major absorption bands of sodalite shifted to lower wave numbers due to heavier Fe atoms substitution in Al lattice sites.