• Proceedings of the KIEE Conference
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• 2007.04a
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• pp.125-127
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• 2007

현재 차량 내 네트워크에서 주로 쓰이는 CAN 프로토콜은 네트워크 내에 다수의 노드가 연결되어 동작하는 경우 우선순위가 낮은 메시지의 전송지연이 심각하게 발생할 수 있다. 이를 해결하기 위해 다양한 제어 방법들이 제안되어 시험되고 있는데, 본 논문에서는 동적 ID 차당 기법을 연로전지 하이브리드 자동차 네트워크 시스템에 적용하여 각 장치들간의 메시지 전송 지연문제를 해결 하며, 또한 이로 인해 발생하는 차량 내 네트워크 시스템의 수행 주기 변화의 문제점을 샘플링 주기 결정 기법을 이용하여 효율적으로 해결하였다.

• 한국정보통신설비학회:학술대회논문집
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• 2006.08a
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• pp.53-56
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• 2006

WiBro service provider have made an effort to provide the subscriber's location and have deployed LBS system using cell-ID method. Cell-ID method has a location error problem if repeater is used on the other cell places at the same time. We introduce and analysis LMU(Location Measurement Unit) on the repeater fer location detection of subscriber which is serviced via the repeater. In this paper we propose the method using LMU on the repeater to avoid these location errors and to provide more exact location to the subscriber. we can conclude that the location error can be more exact at the building which uses repeater. It represents in which level the subscriber is serviced at the building.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06b
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• pp.97-99
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• 2006

본 논문에서는 사용자가 이동하는 공간 전체를 Cell로 정의된 단위로 분할하여 Cell 공간 내에 사용자가 원하는 컨텐츠를 선택적으로 제공할 수 있도록 한다. RFID를 이용한 디스플레이 자동 활성화 방법은 특정영역 내에 RFID(Radio frequency Identification) 태그를 지닌 사용자가 감지되면 사용자가 현재 있는 Cell에 사용자에게 맞는 컨텐츠를 선택적으로 제공해주는 것이다. 제안된 시스템은 RFID 태그. RFID 리더, 프로젝션으로 구성되어 있다. RFID 태그에는 사용자에게 맞는 또는 사용자가 원하는 컨텐츠를 저장하고 있으며, RFID 리더는 안테나를 통해 태그의 ID를 수신하게 되며 프로젝션 부분에서는 수신된 ID에 해당하는 컨텐츠를 제공해준다. 본 논문에서 제안한 시스템은 인터랙티브 디스플레이 환경에서 사용자의 이동에 따른 서비스 제공에 많은 활용이 있을 것이라 기대된다.

• Korean Journal of Food Science and Technology
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• v.47 no.4
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• pp.499-503
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• 2015

We investigated the anti-obesity effects of ethanolic extract (ID1216) of Polygonatum sibiricum rhizome and its potential underlying mechanism in an animal model. ID1216 treatment decreased body weight gain and white adipose tissue weight in the prevention study. The mRNA levels of sirtuin-1 (SIRT1), peroxisome proliferator-activated receptor ${\gamma}$ coactivator-$1{\alpha}$ ($PGC1{\alpha}$), and peroxisome proliferator-activated receptor ${\alpha}$ ($PPAR{\alpha}$) significantly increased in the epididymal white adipose tissue of ID1216-administered mice. The stimulation effects of ID1216 on these gene expressions were also observed in a cell-based assay using differentiated 3T3-L1 adipocytes. In addition, similar to orlistat, ID1216 treatment improved weight gain and reduced epididymal fat in the treatment model. These results suggest that ID1216 has potential as an anti-obesity agent by modulating the expression of genes related to thermogenesis, lipid metabolism and fatty acid oxidation.

• The Korean Journal of Nuclear Medicine
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• v.35 no.3
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• pp.185-191
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• 2001

Objectives: Recently, $[methyl-^{11}C]-({\beta}$-Hydroxyethyl)trimethylammonium ($[^{11}C]$choline) Has been discovered to be a very effective tracer in imaging various human tumors using positron omission tomography. Because of the short half-life of C-11, it is very difficult to use in a routine imaging procedure and needs a frequent synthesis of $[^{11}C]$choline. This can be supplemented by the substitution of $[^{11}C]$choline with $[methyl-^{18}F]$fluorocholine. Here, we would like to report ceil uptake and biodistribution of $[^{11}C]$choline and $[^{18}F]$fluorocholine as a basic study. Methods: $[^{11}C]$Choline was prepared by the treatment of $[^{11}C]CH_3I$ with N,N-dimethylaminoethanol and $[^{18}F]$fluorocholine was synthesized from reaction of $CH_2Br[^{18}F]F$ with N,N-dimethylaminoethanol. The radiochemical purity was checked by high performance liquid chromatography (HPLC). The blodistribution of $[^{11}C]$choline and $[^{18}F]$fluorocholine was determined in balb/c mouse at 5 min, 20 min, 40 min and 80 min. The cell uptake was measured using glioma (9L) and colon adenocarcinoma (SW620). Results: The radiochemical purity was more than 98% after purification. In the liver, uptake did not change over time; the uptake was 20%ID/g for $[^{11}C]$choline and 13%ID/g for $[^{18}F]$fluorocholine. In the kidney, radioactivity decreased over time; the uptake was 15%ID/g for $[^{11}C]$choline and 20%ID/g for $[^{18}F]$fluorocholine, 80 min post-injection. The cell uptake of $[^{11}C]$choline was 4.93% for glioma (9L) and 18.69% for colon adenocarcinoma (SW620). For $[^{18}F]$fluorocholine, 1.77% for glioma (9L) and 2.77% for colon adenocarcinoma (SW620). Conclusion: $[^{11}C]$Choline and $[^{18}F]$fluorocholine showed a different cell uptake tendency, depending on cancer cell line.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1465-1470
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• 2014

Inhibitor of DNA binding 1 (Id1) plays an important role in genesis and metastatic progression of prostate cancer. We previously reported that down regulation of Id1 by small interfering RNA could inhibit the proliferation of PC3 cells and growth of its xenografted tumors. Curcumin, the active ingredient of turmeric, has shown anti-cancer properties via modulation of a number of different molecular regulators. Here we investigated whether Id1 might be involved in the anti-cancer effects of curcumin in vivo and in vitro. We firstly confirmed that curcumin inhibited cell viability in a dose-dependent fashion, and induced apoptosis in PC3 cells, associated with significant decrease in the mRNA and protein expression of Id1. Similar effects of curcumin were observed in tumors of the PC3 xenografted mouse model with introperitoneal injection of curcumin once a day for one month. Tumor growth in mice was obviously suppressed by curcumin during the period of 24 to 30 days. Both mRNA and protein levels of Id1 were significantly down-regulated in xenografted tumors. Our findings point to a novel molecular pathway for curcumin anti-cancer effects. Curcumin may be used as an Id1 inhibitor to modulate Id1 expression.

• Journal of Microbiology and Biotechnology
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• v.31 no.12
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• pp.1716-1721
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• 2021

Chikungunya fever is an arboviral disease caused by the Chikungunya virus (CHIKV). The disease has similar clinical manifestations with other acute febrile illnesses which complicates differential diagnosis in low-resource settings. We aimed to develop a rapid test for CHIKV detection based on the nucleic acid lateral flow immunoassay technology. The system consists of a primer set that recognizes the E1 region of the CHIKV genome and test strips in an enclosed cassette which are used to detect amplicons labeled with FITC/biotin. Amplification of the viral genome was done using open-source PCR, a low-cost open-source thermal cycler. Assay performance was evaluated using a panel of RNA isolated from patients' blood with confirmed CHIKV (n = 8) and dengue virus (n = 20) infection. The open-source PCR-NALFIA platform had a limit of detection of 10 RNA copies/ml. The assay had a sensitivity and specificity of 100% (95% CI: 67.56% - 100%) and 100% (95% CI: 83.89% - 100%), respectively, compared to reference standards of any positive virus culture on C6/36 cell lines and/or qRT-PCR. Further evaluation of its performance using a larger sample size may provide important data to extend its usefulness, especially its utilization in the peripheral healthcare facilities with scarce resources and outbreak situations.

• The Korean Journal of Pharmacology
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• v.25 no.1
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• pp.93-99
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• 1989

In our previous studies, it was found that activities of maternal peripheral lymphocytes and thymocytes were depressed during the implantation period in rats and rabbits. This study was therefore attempted to clarify further this immunosuppression locally by determining lymphocyte response in lymph nodes draining the uterus (DLN) and to elucidate the mechanism by which prostaglandin E (PGE) modulates immune response during the implantation process in rats. As compared with non-pregnant rats, the response of DLN lymphocytes to concanavalin A (Con A) was depressed during the implantation period in 100% of rats studied. The activity of DLN lymphocytes depressed on day 8 of pregnancy was, however, restored partially by the treatment of indomethacin (ID), indicating that prostaglandin (PG) might be one of factors responsible for immunomodulation during the process of implantation. DLN lymphocyte activity in non-pregnant rats was suppressed if PGE was pre-treated prior to Con A and this suppression was partially restored by the treatment of ID. Furthermore, DLN lymphocytes pre-treated with PGE produced PGE in vitro and this PGE production was blocked by the treatment of ID, suggesting that PGE induced PGE-producing cells. However, the pretreatment of estradiol, progesterone, and hCG at doses enough to suppress lymphocyte activity was ineffective in inducing PGE-producing cells. From these results, it is suggested that PGE induces PGE-producing suppressor cells, thereby increasing PGE concentration and PGE in turn depresses maternal local immune response as well as systemic immune response during the implantation period in rats.

• Journal of electromagnetic engineering and science
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• v.10 no.2
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• pp.45-49
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• 2010

This paper presents an analytical formulation of the numerical reflection coefficient of the ID-FDTD scheme at the planar dielectric boundary for a TM wave incidence. The reflection coefficient is formulated in an approximate manner, and the accuracy of this method is numerically verified. The effective dielectric constant for a grid on the interface is obtained, and then reduced to that of the Yee scheme for a small cell size.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.6
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• pp.31-39
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• 2012

This study aims to suggest a methodology of localizing and calibrating parameters, such as acceleration, deceleration, and lane changing which are the basis of car following model in interrupted traffic flow to overcome the limitation of origin and destination based transportation simulation and to verify the application of activity-based model for use in Korean roadway condition in a large scale area or a city. Especially, we figured out that a proper cell size reflecting Korean traffic conditions is 1.0m rather than 7.5m which is default size and a methodology of tracking vehicle behavior characteristics through tracking vehicle ID is suggested on this study. In addition, vehicle running characteristics in real interrupted traffic flow is analyzed through subdividing vehicle types and updating vehicle type ratio. For verification of suggested model, some portion of Dalgubyul-ro in the Daegu city is tested, and the possibility of realization of interrupted traffic flow in simulation is studied.