• Title/Summary/Keyword: Cell network

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Regulatory Network of MicroRNAs, Host Genes, Target Genes and Transcription Factors in Human Esophageal Squamous Cell Carcinoma

  • Wang, Tian-Yan;Xu, Zhi-Wen;Wang, Kun-Hao;Wang, Ning
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.3677-3683
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    • 2015
  • Abnormally expressed microRNAs (miRNAs) and genes have been found to play key roles in esophageal squamous cell carcinoma (ESCC), but little is known about the underlying mechanisms. The aim of this paper was to assess inter-relationships and the regulatory mechanisms of ESCC through a network-based approach. We built three regulatory networks: an abnormally expressed network, a related network and a global network. Unlike previous examples, containing information only on genes or miRNAs, the prime focus was on relationships. It is worth noting that abnormally expressed network emerged as a fault map of ESCC. Theoretically, ESCC might be treated and prevented by correcting the included errors. In addition, the predicted transcription factors (TFs) obtained by the P-match method also warrant further study. Our results may further guide gene therapy researchers in the study of ESCC.

Virtual Resource Allocation in Virtualized Small Cell Networks with Physical-Layer Network Coding Aided Self-Backhauls

  • Cheng, Yulun;Yang, Longxiang;Zhu, Hongbo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.8
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    • pp.3841-3861
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    • 2017
  • Virtualized small cell network is a promising architecture which can realize efficient utilization of the network resource. However, conventional full duplex self-backhauls lead to residual self-interference, which limits the network performance. To handle this issue, this paper proposes a virtual resource allocation, in which the residual self-interference is fully exploited by employing a physical-layer network coding (PNC) aided self-backhaul scheme. We formulate the features of PNC as time slot and information rate constraints, and based on that, the virtual resource allocation is formulated as a mixed combinatorial optimization problem. To solve the problem efficiently, it is decomposed into two sub problems, and a two-phase iteration algorithm is developed accordingly. In the algorithm, the first sub problem is approximated and transferred into a convex problem by utilizing the upper bound of the PNC rate constraint. On the basis of that, the convexity of the second sub problem is also proved. Simulation results show the advantages of the proposed scheme over conventional solution in both the profits of self-backhauls and utility of the network resource.

Cooperative Strategies and Swarm Behavior in Distributed Autonomous Robotic Systems Based on Artificial Immune System (인공 면역계 기반 자율분산로봇 시스템의 협조 전략과 군행동)

  • Sim, Kwee-Bo;Lee, Dong-Wook;Sun, Sang-Joon
    • Journal of Institute of Control, Robotics and Systems
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    • v.6 no.12
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    • pp.1079-1085
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    • 2000
  • In this paper, we propose a method of cooperative control (T-cell modeling) and selection of group behavior strategy (B-cell modeling) based on immune system in distributed autonomous robotic system (DARS). An immune system is the living bodys self-protection and self-maintenance system. these features can be applied to decision making of the optimal swarm behavior in a dynamically changing environment. For applying immune system to DARS, a robot is regarded as a B-cell, each environmental condition as an antigen, a behavior strategy as an antibody, and control parameter as a T-cell, respectively. When the environmental condition (antigen) changes, a robot selects an appropriate behavior strategy (antibody). And its behavior strategy is stimulated and suppressed by other robots using communication (immune network). Finally, much stimulated strategy is adopted as a swarm behavior strategy. This control scheme is based on clonal selection and immune network hypothesis, and it is used for decision making of the optimal swarm strategy. Adaptation ability of the robot is enhanced by adding T-cell model as a control parameter in dynamic environments.

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Statistically Controlled Opportunistic Resource Block Sharing for Femto Cell Networks

  • Shin, Dae Kyu;Choi, Wan;Yu, Takki
    • Journal of Communications and Networks
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    • v.15 no.5
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    • pp.469-475
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    • 2013
  • In this paper, we propose an efficient interference management technique which controls the number of resource blocks (or subcarriers) shared with other cells based on statistical interference levels among cells. The proposed technique tries to maximize average throughput of a femto cell user under a constraint on non-real time control of a femto cell network while guaranteeing a target throughput value of a macro cell user. In our proposed scheme, femto cells opportunistically use resource blocks allocated to other cells if the required average user throughput is not attained with the primarily allocated resource blocks. The proposed method is similar to the underlay approach in cognitive radio systems, but resource block sharing among cells is statistically controlled. For the statistical control, a femto cell sever constructs a table storing average mutual interference among cells and periodically updates the table. This statistical approach fully satisfies the constraint of non-real time control for femto cell networks. Our simulation results show that the proposed scheme achieves higher average femto user throughput than conventional frequency reuse schemes for time varying number of users.

A Performance Analysis of the Virtual CellSystem for Mobile Hosts (이동 호스트를 위한 가상 셀 시스템의 성능 분석)

  • Lim, Kyung-Shik
    • The Transactions of the Korea Information Processing Society
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    • v.5 no.10
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    • pp.2627-2640
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    • 1998
  • In this paper, we analyze the performance of the virtual cell system[1] for the transmission of IP datagrams in mobile computer communications. A virtual cell consistsof a group of physical cells shose base stationsl are implemented b recote bridges and interconnected via high speed datagram packet switched networks. Host mobility is supported at the data link layer using the distributed hierachical location information of mobile hosts. Given mobility and communication ptems among physical cells, the problem of deploying virtual cells is equivalent to the optimization cost for the entire system where interclster communication is more expesive than intracluster communication[2]. Once an iptimal partitionof disjoint clusters is obtained, we deploy the virtual cell system according to the topology of the optimal partition such that each virtual cell correspods to a cluser. To analyze the performance of the virtual cell system, we adopt a BCMP open multipel class queueing network model. In addition to mobility and communication patterns, among physical cells, the topology of the virtual cell system is used to determine service transition probabilities of the queueing network model. With various system parameters, we conduct interesting sensitivity analyses to determine network design tradeoffs. The first application of the proposed model is to determine an adequate network bandwidth for base station networking such that the networks would not become an bottleneck. We also evaluate the network vlilization and system response time due to various types of messages. For instance, when the mobile hosts begin moving fast, the migration rate will be increased. This results of the performance analysis provide a good evidence in demonsratc the sysem effciency under different assumptions of mobility and communication patterns.

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Evaluation of Results in Recent Flexible Solar Cell Research Trends via Network Analysis Method (네트워크 분석을 이용한 플렉시블 태양전지 최근 연구동향 분석)

  • Byun, Kisik;Lim, Jae Sung;Park, Jae Woo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.600-613
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    • 2018
  • The purpose of this research was to introduce a network analysis method for analyzing the recent trend of the flexible solar cell using a scholarly database. Based on the five years from 2013 to 2017, we used centrality analysis of research papers via measurement of degree centrality, closeness centrality, and betweenness centrality. The results of network analysis show that cell has a centrality value above 0.8, which means that cell is connected with 80% of the total keywords, so it is recognized as the center of flexible solar cell research. The analysis results also indicate that perovskite and copper indium gallium diselenide (CuInGaSe2, or CIGS) are the center of the subgroup for cell. We recognize that the result refers to recent new technology called the CIGS/perovskite tandem solar cell. We hope that the network analysis method will be the appropriate and precise tool for technology and research planning via elaboration and optimization.

Inferring genetic regulatory networks of the inflammatory bowel disease in human peripheral blood mononuclear cells

  • Kim, Jin-Ki;Lee, Do-Heon;Yi, Gwan-Su
    • Bioinformatics and Biosystems
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    • v.2 no.2
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    • pp.71-74
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    • 2007
  • Cell phenotypes are determined by groups of functionally related genes. Microarray profiling of gene expression provides us response of cellular state to its perturbation. Several methods for uncovering a cellular network show reliable network reconstruction. In this study, we present reconstruction of genetic regulatory network of inflammation bowel disease in human peripheral blood mononuclear cell. The microarray based on Affymetrix Gene Chip Human Genome U133 Array Set HG-U133A is processed and applied network reconstruction algorithm, ARACNe. As a result, we will show that inferred network composed of 450 nodes and 2017 edges is roughly scale-free network and hierarchical organization. The major hub, CCNL2 (cyclin A2), in inferred network is shown to be associated with inflammatory function as well as apoptotic function.

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A Study on New Cell Switch Fabric for Increasing the Performance of ATM Switching Systems (ATM 교환 시스템의 성능향상을 위한 새로운 셀 스위치 구조 연구)

  • 정진태;이옥재;전병실
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.34S no.3
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    • pp.12-23
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    • 1997
  • In this paper, we propose a new cell switch fabric for increasing the performance of ATM switching systems. Proposed switching network consists of a sorting network and a routing network. Both of these are multistage networks where each stage performs a fixed permutation on the incoming lines, and then routes them through a clumn of 2x2 switching elements. It is designed for distributing inputs and parallel processing to reduce the hardware complexity and obtain high performance of switching network. The structure and the operation of th eswitching network aredescribed and the performanceof the switching network is anlyzed under uniform traffic models. In this result, though the size of proposed network is increased the large scale, it has always the same throughput as the that of genral output queueing system with N=2. So, it is found that our proposed network is appropriate for the high apeed and lrger size of ATM switching systems.

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Cell Grouping Design for Wireless Network using Artificial Bee Colony (인공벌군집을 적용한 무선네트워크 셀 그룹핑 설계)

  • Kim, Sung-Soo;Byeon, Ji-Hwan
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.39 no.2
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    • pp.46-53
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    • 2016
  • In mobile communication systems, location management deals with the location determination of users in a network. One of the strategies used in location management is to partition the network into location areas. Each location area consists of a group of cells. The goal of location management is to partition the network into a number of location areas such that the total paging cost and handoff (or update) cost is a minimum. Finding the optimal number of location areas and the corresponding configuration of the partitioned network is a difficult combinatorial optimization problem. This cell grouping problem is to find a compromise between the location update and paging operations such that the cost of mobile terminal location tracking is a minimum in location area wireless network. In fact, this is shown to be an NP-complete problem in an earlier study. In this paper, artificial bee colony (ABC) is developed and proposed to obtain the best/optimal group of cells for location area planning for location management system. The performance of the artificial bee colony (ABC) is better than or similar to those of other population-based algorithms with the advantage of employing fewer control parameters. The important control parameter of ABC is only 'Limit' which is the number of trials after which a food source is assumed to be abandoned. Simulation results for 16, 36, and 64 cell grouping problems in wireless network show that the performance of our ABC is better than those alternatives such as ant colony optimization (ACO) and particle swarm optimization (PSO).

DANCE : Small AP On/Off Algorithms in Ultra Dense Wireless Network (DANCE : 초고밀도 통신망에서의 소형기지국 온-오프 알고리즘)

  • Lee, Gilsoo;Kim, Hongseok;Kim, Young-Tae;Kim, Byoung-Hoon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38A no.12
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    • pp.1135-1144
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    • 2013
  • Deploying small cells is a reliable and influential solution to handle the skyrocketing traffic increase in the cellular network, and the small cell technology is evolving to ultra-dense network (UDN). In this paper we propose a small cell on/off algorithm with a simple but essential framework composed of access point (AP), user equipment (UE), and small cell controller (SCC). We propose Device-Assisted Networking for Cellular grEening (DANCE) algorithms that save the energy consumption by tying to minimize the number of turned-on APs while maintaining the network throughput. In doing so, SCC firstly gathers the feedback messages from UEs and then makes a decision including a set of turned-on APs and user association. DANCE algorithm has several variations depending on the number of bits of the UE's feedback message (1 bit vs. N bit), and is divided into AP-first, UE-first, or Proximity ON according to the criteria of selecting the turned-on APs. We perform extensive simulations under the realistic UDN environment, and the results confirm that the proposed algorithms, compared to the baseline, can significantly enhance the energy efficiency, e.g., more than a factor of 10.