• Title/Summary/Keyword: Cell Type

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Proposal and Evaluation of Ultra High Speed Wireless Cell Backbone Networks (도시형 초고속 무선통신 셀백본망의 제안 및 평가)

  • 신천우
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.2B
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    • pp.151-157
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    • 2004
  • In this paper, we investigated ultra high speed wireless communication cell backbone net of city using of wireless communication transceiver for millimeter wave band. A new type of 60GHz wave band wireless transceiver using NRD waveguide. This 60㎓ transceiver has excellent signal's absorption characteristics of oxygen molecule than the other millimeter wave bands. We constructed to wireless networks interval within 500m to 3km on wireless backbone node using 60GHz transceivers, and did it so that city type wireless communication cell backbone networks of 155.52MbpsATM(OC-3) may be possible. Therefore, if use transceiver, it is possible that city type ultra high speed wireless communication cell backbone networks construction of 100Mbps, 155.52Mbps, 622Mbps, 1Gbps, and 1.2Gbps degrees.

Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity

  • Kim, Hye-Nan;Chung, Hye-Shin
    • BMB Reports
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    • v.41 no.12
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    • pp.858-862
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    • 2008
  • Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a zinc-dependent proteinase found in cholesterol-rich lipid rafts on the plasma membrane. MT1-MMP hydrolyzes extracellular matrix (ECM) proteins, activates pro-matrix metalloproteinase-2 (proMMP-2) and plays an important role in ECM remodeling, cancer cell migration and metastasis. The role of caveolin-1, an integral protein of caveolae, in the activation of MT1-MMP remains largely unknown. Here, we show that the expression of caveolin-1 attenuates the activation of proMMP-2, reduces proteolytic cleavage of ECM and inhibits cell migration. We utilized the cytoplasmic tail domain deletion (${\Delta}CT$) or the E240A mutant of MT1-MMP. Co-expression of caveolin-1 with the wild-type or the ${\Delta}CT$ MT1-MMP decreased the proMMP-2 activation and inhibited collagen degradation and cell migration. Caveolin-1 had no effect on the catalytically inert E240A MT1-MMP. Our findings suggest that caveolin-1 is essential in the down-regulation of MT1-MMP activity by promoting internalization from the cell surface.

Ultrastructural and Cytochemical Studies on Root Hair Cells of Ginseng(Panax ginseng C.A. Meyer) (인삼(人蔘)(Panax ginseng C.A Meyer) 근모세포(根毛細胞)의 미세구조(微細構造) 및 (세포화학적)細胞化學的 연구(硏究))

  • Jeong, B.K.;Kim, W.K.
    • Applied Microscopy
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    • v.15 no.2
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    • pp.69-79
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    • 1985
  • Ultrastructural and cytochemical studies of the root hair cell and the trichoblast were undertaken with light and electron microscopes to clarify the type of root hair, fine structure and the activities of acid phosphatase and ATPase. The root hair was differentiated from the middle portion of the cell, and perpendicularly to the long axis of the cell. Consequently, the type of root hair comes under the panicoid type. In the trichoblast, nucleus and cytoplasm are located in the vicinity of cortex. On the contrary, after the root hair is formed, they migrate to the apical region of the root hair, and the basal region of the root hair is filled with numerous vacuoles. Cell walls of actively growing root hairs are subdivided into two layers on the basis of the arrangement of cellulose microfibrils. New cell wall of the root hair is presumptively formed from Golgi complex-derived vesicles. Activity of acid phosphatase appeared on tonoplast, plasma membrane, and nuclear envelope, whereas ATPase activity appeared on the plasma membrane, heterochromatin, and mitochondrial cristae.

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EO performance of IPS cell on the inorganic films surface using DuoPIGatron ion source (유기박막표면에 DuoPIGatron 이온소스를 이용한 IPS 셀의 전기광학 특성)

  • Kim, Byoung-Yong;Hwang, Jeoung-Yeon;Kim, Sang-Hun;Han, Jung-Min;Seo, Dae-Shik
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.04a
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    • pp.89-90
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    • 2006
  • Electro-optical (EO) characteristics of in-plane switching (IPS) cell on the polyimide surface using obliquely ion beam (IB) exposure as new ion beam (IB) type system (DuoPIGatrion ion source). A good uniform alignment of the nematic liquid crystal (NLC) alignment with the ion beam exposure on the polyimide surface was observed. In addition, it can be achieved the good EO properties of the ion-beam-aligned IPS-cell on poly imide surface ; the stable VT curve in the ion-beam-aligned IPS cell on a poly imide (PI) surface with ion beam exposure using new type IB equipment was obtained. and the fast response time in the ion-beam-aligned IPS cell on a polyimide (PI) surface with ion beam exposure using new type IB equipment was obtained.

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Inhibitory Effect of Immediate-Type Allergic Reaction by Magnoliac flos (辛夷花에 의한 卽時型 알레르기의 反應 抑制 效果)

  • Jeon, Chang-Ki;Hwang, Chung-yeon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.12 no.1
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    • pp.36-46
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    • 1999
  • The mast cell plays a pivotal role in initiating allergic response by secreting intracytoplasmic granular mediators such as histamine. Magnoliae flos has been used for treatment of allergic disease in Korea. However, its effect in experimental models remains unknown. The present report describes an inhibitory effect of Magnoliae flos on mast cell-mediated immediate-type allergic reactions. Topical application of compound 48/80 can induce an ear swelling response in normal($WBB6F_1-+/+$) mice but not in the congenic mast cell-deficient $WBB6F_1-W/W^v$ mice. Magnoliae flos inhibited concentration-dependently mast cell-dependent ear swelling response induced by compound 48/80 by topical application. Magnoliae flos inhibited concentration-dependently passive cutaneous anaphylaxis induced by anti-dinitrophenyl (DNP) IgE in rats by topical application. Magnoliae flos also inhibited concentration-dependently the histamine release from the rat peritoneal mast cells by compound 48/80 or anti-DNP IgE. Moreover, Magnoliae flos had a significant inhibitory effect on compound 48/80-induced systemic anaphylactic reaction. These results indicate that Magnoliae flos inhibits immediate-type allergic reactions by inhibition of mast cell degranulation in vivo and in vitro.

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The Protective Effect of Lentinus Edodes on Mast Cell-Mediated Immediate-Type Hypersensitivity (비만세포 매개 즉시형 과민반응에 대한 표고버섯 추출물의 보호 효과)

  • Yan, Guanghai;Choi, Yun Ho
    • Korean Journal of Pharmacognosy
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    • v.50 no.3
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    • pp.175-184
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    • 2019
  • Mast cells are crucial as effector cells in the immediate-type allergic reaction. Lentinus edodes has been the popular edible mushroom in oriental countries and reported to have immunomodulatory, anti-tumor, anti-atherogenic, anti-viral, and anti-allergic activities. However, the roles of L. edodes in mast cell-mediated anaphylactic reaction have not been fully elucidated. In this research, we have demonstrated the effects of the methanol extract of L. edodes (MELE) on mast cell-mediated anaphylaxis-like and anaphylactic reactions. MELE suppressed systemic anaphylaxis-like reaction, plasma histamine levels, and ear swelling response in mice treated with compound 48/80. MELE also suppressed passive systemic and cutaneous anaphylaxis mediated by anti-dinitrophenyl IgE. In accordance with these findings, MELE dose-dependently decreased histamine release from RPMC evoked by compound 48/80 or the antigen-antibody reaction. To clarify the mechanism of degranulation system, intracellular cAMP levels as well as calcium influx in RPMC was evaluated. In compound 48/80-treated RPMC, MELE blocked calcium uptake into the cells. In addition, MELE elevated the intracellular cAMP content and significantly attenuated compound 48/80-induced cAMP reduction in RPMC. Taken together, we propose the clinical use of MELE in mast cell-mediated immediate-type allergic diseases.

Studies on Transport Mechanisms of Turtle Bladder I . Epithelium of Urinary Bladder (Turtle bladder의 수송기작(輸送機作)에 관한 연구 : I. 방광(膀胱)의 상피조직(上皮組織))

  • Jeon, Jin-Seok
    • Applied Microscopy
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    • v.19 no.2
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    • pp.119-137
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    • 1989
  • It has been shown in this and earlier investigation that the turtle bladder mucosa has three main cell types on their mucosal surface. They are the granular cells, ${\alpha}$ CA cells, and ${\beta}$ CA cells. The three major transport mechanisms that occurs in the turtle bladder are sodium reabsorption, proton secretion, and bicarbonate secretion. In the present work the trans-port mechanisms by bladder epithelial cells of freshwater turtle, Pseudemys scripta, are summarized as follows. 1. The granular cells play an important role in sodium transport, while the ${\alpha}$ and ${\beta}$ CA cells do not appear to play a determining role in sodium transport. 2. It appears that the active sodium transport in the granular cells occurs in two-step process, implying that first, sodium diffuses into the cells, followed by an energy-dependent efflux step, which is catalyzed by the ouabain-sensitive Na-K ATPase. 3. The ${\alpha}$ type of CA cells are responsible for the proton secretion using the proton pump on the apical plasma membrane, while the ${\beta}$ type of CA cells are believed to be responsible for bicarbonate secretion. 4. When looked at under freeze-fracture electron microscopy, the apical plasma membrane of ${\alpha}$ cells have a characteristic population of rod-shaped intramembranous particles which are believed to be components of the proton pumps. Conversely, ${\beta}$ type of CA cells show rod-shaped particles in their basolateral plasma membranes, which is consistent with the proton absorptive, bicarbonate secretory mechanism. 5. In the turtle bladder, the ${\alpha}$ and ${\beta}$ type of cells are believed to be both responsible for proton transport, but in opposite directions.

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Cell Opening of High Resilience Polyurethane Foam I. Concentration Effect of Polyether Type Cell Opener (고탄성 폴리우레탄 발포체의 기포개방 I. 폴리에테르형 기포개방제의 농도 영향)

  • 송기천;이상목;이동호
    • Polymer(Korea)
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    • v.25 no.5
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    • pp.679-690
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    • 2001
  • High resilience PU foams were prepared with polyether type cell opener. The influences of cell opener concentration on the kinetics, rheology, structural stability morphology and open cell content of the obtained foam were investigated and the role of cell opener during cell opening was determined. And mechanical properties as a function of cell opener concentration were studied. It was observed that urea formation reaction was delayed due to high hydrophilicity of cell opener The decrease of viscosity and the increase of tan $\delta$ were confirmed with increasing cell opener concentration so that the resulted foam had low structural stability and high open cell content. The deterioration of matrix and uniform dispersion of hydrogen-bonded urea in matrix with cell opener concentration was revealed by SEM analysis. As a result, elastic properties of the foam matrix were decreased due to high hydrophilicity of cell opener during the preparation of high resilience polyurethane foam and foam with high open cell content resulted. Hardness, tensile strength, tear strength, elongation of foam were decreased with increasing cell opener concentration.

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Studies of Changes of $Ca^{2+}$-channel Distribution in the Activated Mouse Ova (생쥐 난자의 활성화에 따른 $Ca^{2+}$-channel의 분포 변화에 관한 연구)

  • Chang, Yeon-Soo;Bae, In-Ha
    • Clinical and Experimental Reproductive Medicine
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    • v.28 no.1
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    • pp.13-24
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    • 2001
  • Objective: In muscle and neuronal cells, calcium channels have been classified by electrophysiological and pharmacological properties into (1) voltage-dependent $Ca^{2+}$-channel (1) P/Q-type $Ca^{2+}$-channel (2) N-type $Ca^{2+}$-channel (3) L-type $Ca^{2+}$-channel (4) T-type $Ca^{2+}$-channel (5) R-type $Ca^{2+}$-channel. The present study was done in order to investigate whether there is any difference in $Ca^{2+}$-channel distribution between activated and normally fertilized embryos. Methods: The immunocytochemical method was used to identify the existence of voltage-dependent $Ca^{2+}$-channels in parthenogenetically activated 2-cell embryos by ethanol and $SrCl_2$ treatment. These 2-cell embryos were obtained by exposure to 6% ethanol for 6 min and to 10 mM $SrCl_2$ for 2h. Results: P/Q-type $Ca^{2+}$-channels and L-type $Ca^{2+}$-channels have been identified. Whereas, three type of $Ca^{2+}$-channel P/Q-type, N-type, L-type have been identified in 2-cell embryos fertilized in vivo. Conclusion: Activation by ethanol was faster than those by $SrCl_2$. However, there was difference in DAB staining of the embryos between ethanol and $SrCl_2$ treatment (87.7% and 54.1 %). Intensity of staining was also different between ethanol- and $SrCl_2$-treated group. However, it has not been known why there was some difference in DAB staining and staining intensity in the present study.

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