• 대한세포병리학회지
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• 제14권1호
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• pp.36-41
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• 2003

Epithelioid hemangioendothelioma is a rare vascular tumor of borderline malignancy which is characterized by the presence of "epithelioid" or "histiocytoid" endothelial cells. Superficial and deep tumors have been recognized in the extremities, head, neck, chest, and mediastinum of adult patients. It may also occur as a primary tumor of liver, bone, and other visceral organs. Few effusion cytologic findings of epithelioid hemangioendothelioma have been reported. We report a case of composite epithelioid hemangioendothelioma with focal epithelioid angiosarcomatous areas of the iliac bone and adjacent soft tissue in a 38-year-old female, which, during its metastatic course, was presented as a pleural effusion. The effusion was cellular with epithelioid cells presenting both singly and in clusters. The tumor cells were round to ovoid shewing cytoplasmic vacuolization, variability in cell size, and prominent nucleoli. The effusion smears and cell block sections revealed strong positive staining for CD31 and vimentin, weak positive for CD34 and Factor VIII-related antigen, and negative for cytokeratin, CEA, and calretinin. The cytologic findings in this case were similar to that of metastatic adenocarcinoma or malignant mesothelioma. Therefore, immunocytochemical staining in smear and cell block is a helpful tool to differentiate malignant 'epithelioid' cells in effusion.

• Clinical and Experimental Reproductive Medicine
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• 제27권3호
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• pp.275-282
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• 2000

Objective: This study was to determine the effect of different concentration of calcium III medium on the preimplantational development of zygotes and early 2 cell embryos. Methods: Female mice of ICR strain ($5{\sim}8$ weeks old) were superovulated and mated with fertile males. Zygotes or early 2-cell embryos were collected by flushing the oviducts $31{\sim}32$ hours after hCG injection. The embryos were cultured in various concentrations of $Ca^{2+}$ in medium or with EDTA, EGTA and $Ni^{2+}$. Result and Conclusion: Treatment of high concentraion of $Ca^{2+}$ (3.42 mM $(2X){\sim}17.l$ mM (10X)) in medium didn't develop well compared to the control. Low concentrations of $Ca^{2+}$ (0.214mM $(1/8X){\sim}0.855$ mM (1/2X) were deterimental to development beyond 2-cell stage. EDTA, $Ca^{2+}$ chelating agent was treated with ranged concentrations of EDTA (0.014 $mM{\sim}0.107$ mM) to medium contaning 1.71 mM $Ca^{2+}$ showed beneficial effect to development to blastocyst compared to the control. EGTA, extracellular $Ca^{2+}$ chelator, was treated with ranged concentrations of EGTA ($0.014{\sim}0.107$ mM) to the medium contaning 1.71 mM $Ca^{2+}$. There is no significant difference with the control. $Ni^{2+}$ (50 ${\mu}M$), T-type $Ca^{2+}$-channel blocker was treated to medium contaning low concentration of $Ca^{2+}$. It overcame 2-cell block significantly. Rate of degenerated embryos decreased and developmental rate to morula and blastocyst increased more than low $Ca^{2+}$ concentration alone. Further studies are needed for the overcoming effect of 2-cell block by $Ni^{2+}$.

• 한국정보통신학회논문지
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• 제11권1호
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• pp.139-149
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• 2007

비동기 OFCDM 시스템은 동기 시스템과 달리 반드시 셀 탐색과정을 가져야 한다 이 과정을 초기 동기라고 하며 초기 동기를 위한 셀 탐색 방법이 다음과 같이 3단계 방법으로 수행된다. 셀 탐색 1 단계에서 보호구간의 상관을 이용한 OFCDM 심볼 동기 즉, FFT 윈도우 타이밍 추정과 탐색 2 단계에서는 주파수영역에서 CSSC(Cell Specific Scrambling Code) 위상 천이성질을 이용한 CPICH(Common Pilot Channel)의 상관을 획득함으로써 프레임 타이밍 및 CSSC 그룹을 검출하고 마지막으로 탐색 3 단계에서 그룹 안에 속한 CSSC 위상 즉, 최적의 CSSC를 얻게 된다. 본 논문에서는 기존의 CPICH를 기반으로 하는 3단계 셀 탐색과정 중 2단계에서 그룹을 나타내는 그룹코드를 블록형태로 변형하여 이동국의 복잡도를 줄인다. 그러나 복잡도를 줄이면 성능에 영향을 주지만 블록형태로 구성했을 때 최소의 성능열화를 가지는 조합을 찾는다. 제안된 적절한 조합을 가지는 블록형태의 그룹코드는 모의실험 통하여 기존의 그룹코드와 거의 동일한 성능을 유지하면서 복잡도를 줄일 수 있음을 비교 검증하였다.

• 한국멀티미디어학회논문지
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• 제18권10호
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• pp.1180-1188
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• 2015

In this paper, a parallel cell contour line extraction algorithm using CUDA, which has no inner contour lines, is proposed. The contour of a cell is very important in a cell image analysis. It could be obtained by a conventional serial contour tracing algorithm or parallel morphology operation. However, the cell image has various damages in acquisition or dyeing process. They could be turn into several inner contours, which make a cell image analysis difficult. The proposed algorithm introduces a min-max coordinates table into each CUDA thread block, and removes the inner contour in parallel. It is 4.1 to 7.6 times faster than a conventional serial contour tracing algorithm.

• 한국전자파학회논문지
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• 제10권1호
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• pp.99-108
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• 1999

본 논문에서는 LMDS(Local Multipoint Distributed Services) 시스템의 역방향 채널에서 TDMA(Time D Division Multiple Access) 방식으로 ATM(Asynchronous Transfer Mode) 셀을 효율적으로 전송하기 위해 전치부호를 줄일 수 있는 블록복조 알고리즘을 적용한 $\pi$/4 QPSK 변복조 방식 시스댐을 제안하고. 블록복 조의 동기성능을 향상시키기 위해 새로운 반송파 동기회로를 설계하였다. 제안한 블록동기복조 알고리즘을 적용한 $\pi$/4 QPSK 변복조 방식 시스템은 LMDS 환경에서 ATM 셀 단위의 버스트 데이터로 반송파 위상동 기. 심별 타이밍 동기, 슬롯 타이밍 동기 등을 수행할 때 전치부호를 아주 적게 사용하므로 효율적인 프레임 전송을 얻어질 수 있도록 하고 있다. 본 논문에서 제안한 블록동기복조 알고리즘을 적용한 $\pi$/4 QPSK 변복 조 방식 시스템을 모의설험을 통하여 분석한 결과. 페이딩 환경에서 심벌 타이멍 옹기, 주파수 오프셋, 반송 파 위상동기할 때 전치부호를 아주 적게까지 줄이더라도 좋은 성능을 발휘함을 확인할 수 있었다.

• The Korean Journal of Physiology and Pharmacology
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• 제10권2호
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• pp.71-77
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• 2006

The goal of this study was to analyze the effects of genistein, a widely used tyrosine kinase inhibitor, on cloned Shaw-type $K^+$ currents, Kv3.1 which were stably expressed in Chinese hamster ovary (CHO) cells, using the whole-cell configuration of patch-clamp techniques. In whole-cell recordings, genistein at external concentrations from 10 to $100{\mu}M$ accelerated the rate of inactivation of Kv3.1 currents, thereby concentration-dependently reducing the current at the end of depolarizing pulse with an $IC_{50}$ value of $15.71{\pm}0.67{\mu}M$ and a Hill coefficient of $3.28{\pm}0.35$ (n=5). The time constant of activation at a 300 ms depolarizing test pulses from -80 mV to +40 mV was $1.01{\pm}0.04$ ms and $0.90{\pm}0.05$ ms (n=9) under control conditions and in the presence of $20{\mu}M$ genistein, respectively, indicating that the activation kinetics was not significantly modified by genistein. Genistein $(20{\mu}M)$ slowed the deactivation of the tail current elicited upon repolarization to -40 mV, thus inducing a crossover phenomenon. These results suggest that drug unbinding is required before Kv3.1 channels can close. Genistein-induced block was voltage-dependent, increasing in the voltage range $(-20\'mV{\sim}0\'mV)$ for channel opening, suggesting an open channel interaction. Genistein $(20{\mu}M)$ produced use-dependent block of Kv3.1 at a stimulation frequency of 1 Hz. The voltage dependence of steady-state inactivation of Kv3.1 was not changed by $20{\mu}M$ genistein. Our results indicate that genistein blocks directly Kv3.1 currents in concentration-, voltage-, time-dependent manners and the action of genistein on Kv3.1 is independent of tyrosine kinase inhibition.

• 약학회지
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• 제52권5호
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• pp.412-417
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• 2008

BAY11-7082 was initially found to be an anti-inflammatory drug with NF-${\kappa}B$ inhibitory property. In this study, we evaluated modulatory function of BAY11-7082 on U937 cell-cell adhesion induced by CD29 (${\beta}1$-integrins). BAY11-7082 strongly blocked functional activation of CD29 (${\beta}1$-integrins), as assessed by cell-cell adhesion assay. However, this compound did not block a simple activation of CD29, as assessed by cell-fibronectin adhesion assay. In particular, to understand molecular mechanism of BAY11-7082-mediated inhibition, the regulatory roles of CD29-induced actin cytoskeleton rearrangement under cell-cell adhesion and surface level of CD29 were examined using confocal and flow cytometic analysis. Interestingly, this compound strongly suppressed the molecular association of actin cytoskeleton with CD29 at cell-cell adhesion site. Moreover, BAY11-7082 also diminished surface levels of CD29 as well as its-associated adhesion molecule CD147, but not other adhesion molecules such as CD18 and CD43. Therefore, our data suggest that BAY11-7082 may be involved in regulating immune responses managed by CD29-mediated cell-cell adhesion.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2006년도 춘계학술대회
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• pp.206-209
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• 2006

In this paper, I try to measure the electrical characteristics of PV cell for lanterns with solar simulator and simulated with PC1D software. I keep my eye on the characteristics variation of PV cell as a temperature change. Therefore, I try to increase a temperature of controlled block from $10^{\circ}C$ to $50^[\circ}C$ while measuring the FV cell. As a result, A variation caused by voltage have an effect on the efficacy of PV cell. Hence it is an important variable when a designer plan to make a solar cell for lanterns.

• 한국전자파학회:학술대회논문집
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• 한국전자파학회 2005년도 종합학술발표회 논문집 Vol.15 No.1
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• pp.131-136
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• 2005

UWB is the most spotlighted wireless technology that transmits data at very high rates using low power over a wide spectrum of frequency band. UWB technology makes it possible to transmit data at rate over 100Mbps within 10 meters. To preserve important header information, MB-OFDM UWB adopts Reed-Solomon(23,17) code. In receiver, RS decoder needs high speed and low latency using efficient hardware. In this paper, we suggest the architecture of RS decoder for MB-OFDM UWB. We adopts Modified-Euclidean algorithm for key equation solver block which is most complex in area. We suggest pipelined processing cell for this block and show the detailed architecture of syndrome, Chien search and Forney algorithm block. At last, we show the hardware implementation results of RS decoder for ASIC implementation.

• 한국정보기술응용학회:학술대회논문집
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• 한국정보기술응용학회 2005년도 6th 2005 International Conference on Computers, Communications and System
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• pp.195-198
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• 2005

UWB is the most spotlighted wireless technology that transmits data at very high rates using low power over a wide spectrum of frequency band. UWB technology makes it possible to transmit data at rate over 100Mbps within 10 meters. To preserve important header information, MBOFDM UWB adopts Reed-Solomon(23,17) code. In receiver, RS decoder needs high speed and low latency using efficient hardware. In this paper, we suggest the architecture of RS decoder for MBOFDM UWB. We adopts Modified-Euclidean algorithm for key equation solver block which is most complex in area. We suggest pipelined processing cell for this block and show the detailed architecture of syndrome, Chien search and Forney algorithm block. At last, we show the hardware implementation results of RS decoder for ASIC implementation.