• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.11
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• pp.5947-5955
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• 2013

This study was intended to estimate the axial deformation of joint between pavement modules in the rapid-constructible modular pavement system, and to investigate the applicability of two-phase composites for a joint material, which was composed of cement paste, epoxy, or polyurethane as a matrix and sand as particles. A case which had supports under the pavement module as well as a case which the module was put on roadbed directly were considered in FEM analysis for the axial deformation. The effect of self-weight, live load, thermal change, and drying shrinkage were estimated and the thermal change was found to cause the largest deformation compared to the others. Deformation capacity of two-phase composites was predicted using the modified shear-lag model. In the analytical results for the elastic modulus and maximum tensile strain with different volume fractions of sand, 20~30 % replacement of sand was revealed to satisfy the required strain capacity with economy when if the width of joint was designed to be 15~20 mm.

• Journal of Korean Society of societal Security
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• v.4 no.2
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• pp.57-64
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• 2011

Although it is uncertain that the cause of changed pattern of the natural disaster related to water (i.e. flood and drought) is due to excessive carbon dioxide yielded from economic activity or the increased number of sunspots, it is apparent that there have been unusual climate change that directly affects the water resource management. Due to such a frequent unusual weather activities, there have been increased natural disaster and the most direct and major reason is considered as climate change. As we see, the climate change necessarily causes social costs. Especially, the effects on the water resource due to flood and drought take the considerable part of such costs. Therefore, this study is basic work to develop a new economic analysis technique to be used in pursuing appropriate adaptation project in field of the amount of cost damage through analysis of the effects of the climate change on the water resource. The models appeared in many reports for cost assessment of climate change were various (e.g., PAGE, DICE, AIM, IMAGE, MERGE, and etc.) and this report summarizes general characteristics of each model. To assess the effects of climate change of the water management, we defined the field of the water management on climate change. The results help post-study in field of the climate change's social-economic effect assessment, can be employed for the prioritizing process of the national fund's investment.

• Journal of the Korean Institute of Gas
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• v.19 no.2
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• pp.12-19
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• 2015

$CO_2$ is non-flammable, non-toxic gas and not cause of chemical explosion. However, various impurities and some oxides can be included in the captured $CO_2$ inevitably. While the $CO_2$ gas was temporarily stored, the pressure in a storage tank would be reached above 100bar. Therefore, the tank could occur a physical explosion due to the corrosion of vessel or uncertainty. Evaluating the intensity of explosion can be calculated by the TNT equivalent method generally used. To describe the physical explosion, it is assumed that the capacity of a $CO_2$ temporary container is about 100 tons. In this work, physical explosion damage in a $CO_2$ storage tank is estimated by using the Hopkinson's scaling law and the injury effect of human body caused by the explosion is assessed by the probit model.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.191-200
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• 2017

Smart work is an alternative form to enable seamless business collaboration without time and space limitations using ICT. However, smart work implementation has not produced tangible achievements and sometimes has resulted in failure. This study examined users' resistance against smart work, which is regarded as one of the most important elements for the successful implementation of smart work. The study classified elements which cause users' resistance into the work's innovative characteristics and the user characteristics based on the model of innovation resistance. It also set the degree of freedom in spatial and temporal dimension as moderating factors. This empirical research results showed that low work efficiency, unfavorable evaluation methods, and high degree of satisfaction in the way of working affected smart work users' resistance. In addition, temporal freedom had a moderating effect on the relationship between users' characteristics and their resistance. On the contrary, spatial freedom affected the relationship between their works' innovative characteristics and their resistance. The study results suggest that organizations need to set up business processes and evaluation methods first to adopt Smart work successfully.

• Journal of Korean Tunnelling and Underground Space Association
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• v.25 no.1
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• pp.27-41
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• 2023

Submerged floating tunnels must be connected to the ground to connect continents. The displacement imbalance at the shore connection between the underground bored tunnel and submerged floating tunnel can cause stress concentration, accompanying a fracture at the shore connection. The elastic joint has been proposed as a method to relive the stress concentration, however, the effect of the elastic joints on the dynamic behavior should be evaluated. In this study, the submerged floating tunnel and shore connection under dynamic load conditions were simulated through numerical analysis using a numerical model verified through a small-scaled physical model test. The resonant frequency was considered as a dynamic behavioral characteristic of the tunnel under the impact load, and it was confirmed that the stiffness of the elastic joint and the resonant frequency exhibit a power function relationship. When the shore connection is designed with a soft joint, the resonant frequency of the tunnel is reduced, which not only increases the risk of resonance in the marine environment where a dynamic load of low frequency is applied, but also greatly increases the maximum velocity of tunnel when resonance occurs.

• Parasites, Hosts and Diseases
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• v.61 no.1
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• pp.60-71
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• 2023

Cockroaches can cause allergic sensitization in humans via contact with their feces or frass. Antibiotics can affect concentration of major allergen and total bacteria production in German cockroaches (Blattella germanica). This study examined the ability of antibiotic-treated German cockroaches to induce allergic airway inflammation and the effect of antibiotics on their lipopolysaccharide and Bla g1, 2, and 5 expression levels. Specifically, we measured the ability of German cockroach extract (with or without prior antibiotic exposure) to induce allergic inflammation in human bronchial epithelial cells and a mouse model of asthma. Bacterial 16S rRNA and lipopolysaccharide levels were lower in ampicillin-treated cockroaches than in the control group. The Bla g1, Bla g2, and Bla g5 expression in ampicillin-treated cockroaches decreased at both the protein and RNA levels. In human bronchial epithelial cell lines BEAS-2B exposed to the ampicillin-treated extract, expression levels of interleukin-6 and interleukin-8 were lower than that in the control group. The total cell count and eosinophil count in bronchoalveolar lavage fluid was also lower in mice exposed to the ampicillin-treated extract than in those exposed to normal cockroach extract. Mouse lung histopathology showed reduced immune cell infiltration and mucus production in the ampicillin group. Our results showed that ampicillin treatment reduced the symbiont bacterial population and major allergen levels in German cockroaches, leading to reduced airway inflammation in mice. These results can facilitate the preparation of protein extracts for immunotherapy or diagnostics applications.

• IMMUNE NETWORK
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• v.20 no.5
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• pp.40.1-40.15
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• 2020

The protein encoded by the Gene Associated with Retinoid-Interferon-Induced Mortality-19 (GRIM-19) is located in the mitochondrial inner membrane and is homologous to the NADH dehydrogenase 1-alpha subcomplex subunit 13 of the electron transport chain. Multiple sclerosis (MS) is a demyelinating disease that damages the brain and spinal cord. Although both the cause and mechanism of MS progression remain unclear, it is accepted that an immune disorder is involved. We explored whether GRIM-19 ameliorated MS by increasing the levels of inflammatory cytokines and immune cells; we used a mouse model of experimental autoimmune encephalomyelitis (EAE) to this end. Six-to-eight-week-old male C57BL/6, IFNγ-knockout (KO), and GRIM-19 transgenic mice were used; EAE was induced in all strains. A GRIM-19 overexpression vector (GRIM19 OVN) was electrophoretically injected intravenously. The levels of Th1 and Th17 cells were measured via flow cytometry, immunofluorescence, and immunohistochemical analysis. IL-17A and IFNγ expression levels were assessed via ELISA and quantitative PCR. IL-17A expression decreased and IFNγ expression increased in EAE mice that received injections of the GRIM-19 OVN. GRIM19 transgenic mice expressed more IFNγ than did wild-type mice; this inhibited EAE development. However, the effect of GRIM-19 overexpression on the EAE of IFNγ-KO mice did not differ from that of the empty vector. GRIM-19 expression was therapeutic for EAE mice, elevating the IFNγ level. GRIM-19 regulated the Th17/Treg cell balance.

• Information Systems Review
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• v.16 no.2
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• pp.77-95
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• 2014

From the success of TDX and CDMA to today's social media boom, Korea's ICT has achieved an amazing growth for the last couple of decades. However, in spite of ICT's role as an engine of growth in Korea, there have been concerns that ICT growth would negatively affect national employment due to the labor substitution effect. While some scholars insist that ICT would positively affect employment because it will enlarge the size of industry itself, many people blame ICT as a main culprit of rising unemployment rates. In this study, we try to empirically find the true effect of ICT growth on employment in Korea. We use the data of ICT productions, ICT investments, and various industries employments from 1995 to 2011. The methodologies we adopted for this study is Granger causality tests and impulse response functions based on vector autoregression (VAR) model. We find that ICT has negative impact on service industries, while it has positive impact on manufacturing industries. Meanwhile, ICT has no statistically significant impact on ICT industry itself. Since the impacts of ICT on employment are mixed, we can argue that ICT should not be blamed for the main cause of low employment. We suggest a direction of future policies to utilize ICT for vitalizing employments in Korea.

• Korean Journal of Organic Agriculture
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• v.21 no.4
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• pp.711-723
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• 2013

The objectives of this study were to access climate change by global warming in Korea, and to investigate its effects on production efficiency of lactating dairy cows. Two regions, Daegu and Daekwanryung, were selected to represent a warm and a cold area, respectively. Time-series analyses on meteorological records for 25 years (from January 1, 1988 to December 31, 2012) revealed significant and different climate changes in two regions. In the warm area there has been a significant (P<0.05) increase in low temperature during the summer, which can cause heat stress to the animal. On the other hand, a decrease in low temperature during the winter was observed in the cold region (P<0.01), and cold stress in winter can thus be an issue in this region. Simulations using a model integrated the Korean feeding standard for dairy cattle and the environmental effect module of Cornell Net Carbohydrate and Protein System, indicated that a reduction in feed efficiency can be a problem during the winter in the cold region while during the summer in the warm area. We conclude that the effect of climate change by global warming varies in different areas in Korea and a region-specific management strategy should be developed in order to maintain productivity, health and welfare of lactating dairy cows.

• Journal of The Korean Society of Agricultural Engineers
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• v.60 no.3
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• pp.71-81
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• 2018

$CO_2$ concentration has a significant effect on quality of cold-stored apples. High indoor $CO_2$ concentrations above 10,000 ppm cause the browning of apples and result in economic loss for farmers. The purpose of this study is to evaluate $CO_2$ concentrations and their distribution in a controlled atmosphere (CA) storage and provide better structural designs to improve the $CO_2$ environment using computational fluid dynamics (CFD) simulations. The CFD model was developed for a real CA storage for apples and applied to investigate the effect of changing the inlet and outlet locations and the aspect ratio of the floor of the CA storage on the spatial distributions of $CO_2$ concentration and the browning of the apples. The lowest $CO_2$ concentrations in existing CA storage with a high aspect ratio of the floor were achieved from the combination of the inlet located at the top of the right side and the outlet located at the bottom of the left side. In modified CA storage with a low aspect ratio, the combination of the inlet and outlet located at top and bottom of left side respectively achieved the lowest $CO_2$ concentrations. The proposed case enhanced the storage performance by reducing total browned apples by 3.6% in storage duration of 210 days. This study is expected to reduce the browning damages of apples in CA storage, and thus greatly prevent economic losses.