• Journal of Chest Surgery
• /
• v.20 no.3
• /
• pp.557-564
• /
• 1987

From September 1980 to July 1986, 135 cases of cardiac valve surgery were performed under the cardiopulmonary bypass. Out of 135 cases, single valve surgery was 114 cases including open mitral commissurotomy 17, mitral annuloplasty 2, mitral valve replacement 85, and aortic valve replacement 10 and double valve surgery was 21 cases. There were 68 males and 67 females ranging from 9 to 57 years of age. Early death within 30 days after operation was 17 cases [12.6%] and caused of death were ventricular arrhythmia 5, low cardiac output syndrome 4, excessive bleeding 3, pulmonary complication 2, and so on. Among 118 early survivors, 5 cases [5.1%] of late death were developed over a period of 2 to 72 months, and main cause of death was fatal bleeding complication associated with anticoagulation therapy. Symptomatically, 91.8% of patients were in NYHA functional class I or II at the end of the follow-up.

• Journal of Sasang Constitutional Medicine
• /
• v.21 no.2
• /
• pp.58-71
• /
• 2009

1. Objectives : The Crown Prince Sohyen(1612-1645) has been believed ro have been poisoned to death because of the political conflict with the King Injo. However, the Crown Prince Sohyen who was So-yangin(SY type) didn't be treated properly at that time. This paper is supposed to explain the reason why he died by reference. 2. Methods : The prescription which was made out to the Crown Prince Sohyen is analyzed, based on the Sasang Constitutional Medicine(SCM) through Shimyang-ilgy and Ulyudongkung-ilgy. 3. Results : 1) In the case of the prescription where So-yang medical stuffs were contained a lot or Gunyak(the main madical stuff) was So-yang one, the Crown Prince Sohyen was better, while that of Tae-eum and So-eum medical stuffs didn't work. Therefore, the Crown Prince Sohyen can be considered So-yangin. 2) The So-yang in's symptom was misunderstood as Hakjil and treated, which could lead him to be put to death 4. Conclusions : The Crown Prince Sohyen is supposed to be Soyang-in(SY type), and accordingly the So-yang in's symptom was misunderstood as Hakjil and treated, which could cause him to pass away.

• Biomolecules & Therapeutics
• /
• v.12 no.2
• /
• pp.92-100
• /
• 2004

Effect of the depletion or oxidation of GSH on mitomycin c (MMC)-induced mitochondrial damage and cell death was assessed in small cell lung cancer (SCLC) cells. MMC induced cell death and the decrease in the GSH contents in SCLC cells, which were inhibited by z-LEHD.fmk (a cell permeable inhibitor of caspase-9), z-DQMD.fmk (a cell permeable inhibitor of caspase-3) and thiol compound, N-acetylcysteine. MMC caused nuclear damage, release of cytochrome c and activation of caspase-3, which were reduced by N-acetylcysteine. The depletion of GSH due to L-butionine-sulfoximine enhanced the MMC-induced cell death and formation of reactive oxygen species in SCLC cells, whereas the oxidation of GSH due to diamide or $NH_2Cl$ did not affect cytotoxicity of MMC. The results show that MMC may cause cell death in SCLC cells by inducing mitochondrial dysfunction, leading to activation of caspase-9 and -3. The MMC-induced change in the mitochondrial membrane permeability, followed by cell death, in SCLC cells may be significantly enhanced by the depletion of GSH. In contrast, the oxidation of GSH may not affect cytotoxicity of MMC.

• Journal of Environmental Health Sciences
• /
• v.34 no.5
• /
• pp.361-368
• /
• 2008

Objective to assess whether exposure to air pollutants is associated with postneonatal infant death, using a timeseries methodology, between 1999 and 2003 in Seoul, Korea.. Methods We investigated the short-term effects of air pollution for 548,725 live births during the study period. The daily count of postneonatal infant deaths from all causes and from SIDS (sudden infant death syndrome) by birth order was analyzed by a Generalized Additive Poisson model, with controlling for the effects of seasonal trends, air temperature, relative humidity, barometric pressure, and day of the week as covariates. Results During the study period, we observed 699 deaths from all causes and 47 deaths from SIDS. We did not find any significant associations between daily mortality and ambient levels of air pollutants except for CO and $NO_2$. The estimated relative risk of postneonatal infant death from all causes was 1.17 (95% CI=1.04-1.32) and 1.16 (95% CI=1.03-1.29) by IQR (interquartile range) for CO and $NO_2$ respectively. Also, we observed no clear trend of the mortality effects of air pollution by birth orders. Conclusion In conclusion, our findings suggest that air pollution, in general, influenced adversely postneonatal infant death from all-cause and SIDS although it was not statistically significant. This study may support that the rationale.

• Journal of Korean Medical classics
• /
• v.23 no.1
• /
• pp.115-124
• /
• 2010

King Heonjong was the twenty-fourth King of the Joseon Dynasty. He took the throne when he was only 8 years old, and had to go through power politics of maternal relations. During his period, situations worsened in both domestic and foreign affairs, meaning the beginning fall of the Joseon Dynasty. In respect to the diseases and treatments of King Heonjong, there appeared very few articles compared with the previous Kings, in the Annals of the Joseon Dynasty, the Journal of Royal Secretariat, and the Diary of Kings of the Joseon Dynasty. He caught small pox and recovered in 10 days at the age of 17. Some articles showed that he suffered from symptom of indigestion, dyspepsia and edema. He died at 23 and had no descendants. We assume that the cause of death was due to worsening of kidney failure.

• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.121.3-122
• /
• 2003

This report describes the fatal case of a 13-year-old middle school girl(MSG) whose cause of death might be attributed to a intoxication involving Venlafaxine(VEN). MSG's mother had the history of depression for 11 years. She and her daughter were found dead in the same room of their apartment, with hanged herself. We analyzed the postmortem of MSG which were requested to our institute for the cause of her death. We couldn't get any blood samples from MSG's postmortem. (omitted)

• International Journal of Vascular Biomedical Engineering
• /
• v.2 no.1
• /
• pp.1-10
• /
• 2004

Circulatory disease is the number two cause of death next to cancer in Korea, while the cardiovascular disease alone is the number one cause of death in the US. In the present article, some background, current status and future prospects of biomedical engineering esearch on circulatory disorders are discussed in terms of the origin of atherosclerosis, computational fluid dynamics and medical imaging techniques, clinical treatments and fluid dynamics, advances in stents, hemodynamic analysis of artificial heart, and artificial blood. In particular, the importance of close collaboration of medicine and fluids engineering is emphasized.

• Korean Journal of Artificial Intelligence
• /
• v.11 no.3
• /
• pp.23-27
• /
• 2023

The purpose of this study is to identify and analyze suicide factors of adolescents using the Random Forest algorithm. According to statistics on the cause of death by the National Statistical Office in 2019, suicide was the highest cause of death in the 10-19 age group, which is a major social problem. Using machine learning algorithms, research can predict whether individual adolescents think of suicide without investigating suicidal ideation and can contribute to protecting adolescents and analyzing factors that affect suicide, establishing effective intervention measures. As a result of predicting with the random forest algorithm, it can be said that the possibility of identifying and predicting suicide factors of adolescents was confirmed. To increase the accuracy of the results, continuous research on the factors that induce youth suicide is necessary.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.16 no.2
• /
• pp.209-214
• /
• 2002

At this paper, I classified ‘tetanus’ in 『DongEuiBoGam』 and studied the concept, causes, symptoms, pathological mechanisms of that disease and then I had a new understanding that concept of tetanus in 『DongEuiBoGam』 is different with concept of tetanus in Western Medicine. In the mean time, I investigated the classification in 「Classification of Korean Standard Cause of Death(Oriental Medicine)」 (1995, The Korean Economic Planning Board), and concluded the concept of tetanus in "DongEuiBoGam".

• The Journal of Korean Medical History
• /
• v.24 no.2
• /
• pp.125-134
• /
• 2011

King Gojong was the twenty-sixth King in the Choseon Dynasty. He took the throne when he was only 12 years old and had to set up regency for 10 years. During his period, situations were worsened in both domestic and foreign affairs. In the end, after 3 years from abdication of the throne, the Choseon Dynasty was overthrown in compliance with a coercion by Japanese empire. He died in 68 years old. We can assume that his inveterate disease are weakness of the spleen and the stomach. In addition, he suffered from a boil, a cold, dermatosis, eye disease, an external wound, dentistry disease, arthritis, etc. The official cause of his death was cerebral hemorrhage. But we assume that the possibility of poison murdering is high.