• Natural Product Sciences
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• 제13권1호
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• pp.6-10
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• 2007

The ethanolic (50% v/v) extracts of Carissa carandas (fruits) (Apocynaceae) and Microstylis wallichii (tubers) (Orchidaceae) were examined for anti-inflammatory and analgesic activities in experimental animals. Carissa carandas and Microstylis wallichii (50-200 mg/kg) caused a dose dependent inhibition of swelling caused by carrageenin significantly in cotton pellet induced granuloma in rats (P < 0.05 to P < 0.001). There was a significant increase in the analgesy meter induced pain in rats. The extracts of Carissa carandas and Microstylis wallichii resulted in an inhibition of stretching episodes and percentage protection was 16.05-17.58%respectively in acetic acid induced writhing.