• Journal of Chest Surgery
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• v.14 no.1
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• pp.26-32
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• 1981

Three cases of tricuspid atresia were treated by Fontan varieties of operation in this department in 1980. The first case was 19 year old girl who underwent Glenn operation at the age of 6 years. Her second operation was done with ASD closure and 16mm Ionescu-Shiley valved conduit insertion between right atrium and main pulmonary artery. The second case was a 5 year old boy who underwent Kreutzer operation successfully utilizing 14mm Ionescu-Shiley va]ved conduit. The above mentioned 2 cases were Type Ib after Keith`s classification, whose immediate postoperative courses were complicated by pleura] effusion [in 2nd case chylothorax] hepatomegaly, and ascites. Those complications were relieved completely by medical treatment and closed thoractomy; Postoperative follow-up up to 11 months and 1 year periods were satisfactory with disappearance of cyanosis and dyspnea. The third case was a 8 year old boy who had complete TGA with TA [Keith`s Type IIb] who underwent Kreutze`s operation utilizing 14mm Ionescu-Shiley valved conduit, he died of low cardiac output Immediately after open heart surgery.

• Herbal Formula Science
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• v.26 no.3
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• pp.261-265
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• 2018

Objective : This discussion was performed in order to find a meaning of Mahwang, Gyeji, Sesin, Buja and Related Prescriptions connected to the distribution problem of body fluid caused by inflammation. Methods : The pharmacological effects of the prescriptions including Mahwang, Gyeji, Sesin, Buja and these herbs which are used as an individual case were investigated literally. Results : Mahwang, Gyeji, Sesin, Buja and the prescriptions including these herbs have the effect of strengthening heart and increasing cardiac output. Therefore it can be thought that the effect of distributing body fluid is included in the Mahwang, Gyeji, Sesin, Buja and Related Prescriptions. And especially the effect of mahwang could not be restricted to the diaphoretic effect. The effect of Mahwang could be interpreted as the distributing body fluid effect through the stimulation of sympathetic nervous system and inhibition of parasympathetic system. Conclusion : Mahwang, Gyeji Sesin and Buja and related prescriptions have the effect of distributing body fluid via stimulation of sympathetic system.

• Korean Journal of Clinical Laboratory Science
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• v.45 no.3
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• pp.96-101
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• 2013

Increased waist circumference has shown to be more strongly associated with cardiovascular disease risk factors. The purpose of this study is to investigate the association between exercise capacity and cardiovascular risk factors among obese types in adult men. The subjects of this study were a total fifty-four obese persons and obesity criteria is body mass index $(BMI){\geq}25kg/m^2$. Diagnostic criteria for obesity was defined as a waist circumference of ${\geq}90cm$. The BMI in the obese subjects, as judged by the presence or absence of abdominal obesity, were classified into two groups (non-AO: without abdominal obesity group, AO: with abdominal obesity group). AO presented lower total exercise time, metabolic equivalents (METs) than Non-AO. AO showed slow HRR (heart rate recovery) response. HRR was negative correlated with BMI, body fat mass, waist circumference. AO had a high heart rate and a low cardiac output in submaximal exercise stage 1~2. In conclusion, AO's (with abdominal obesity groups) total exercise time, METs and HRR are lower than Non-AO. HRR is related with BMI, body fat mass and waist circumference.

• Journal of Biomedical Engineering Research
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• v.19 no.1
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• pp.47-52
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• 1998

To develop the supplementary heart valve which could reduce the complications of prosthetic heart valve, in vitro experiments were performed to analyze the movement of the supplement valves from the view point of the flow dynamics and leaflet dynamics. The autologous pericardium was attached to deficient portion of the porcine valve which was dissected completely and partially. The pericardium was treated by buffered glutaraldehyde solution in the preshaped mould to preserve the shape of the leaflet. The function of the valves were evaluated in the mock circulatory system and three sets of experiment were performed. The instantaneous motion of the leaflet was pictured by the 35mm camera and the pressure drop through the valve and cardiac output were measured. The supplementary valve which was replaced completely performed better thatn the valve replaced partially. In vitro experiments showed that the supplementary valve which was replaced completely performed better than the valve replaced partially. In vitro experiments showed that the supplementary valve could undertake the prosthetic heart valve in clinic.

• Journal of Korean Biological Nursing Science
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• v.11 no.1
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• pp.68-76
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• 2009

Purpose: The purpose of this study was to evaluate the hemodynamic changes in degree and duration that occur during Valsalva maneuver (VM). Furthermore, we wanted to investigate the patterns and mechanisms of physiological hemodynamic control. Method: Thirty six healthy college students were recruited from Y university. Each participant was provided with written informed consent. Blood pressure (BP), heart rate (HR), cardiac output (CO) were continuously recorded using the Finometer. Result: During the phase I of VM, means of systolic and diastolic pressures were increased by 32.15% and 38.28%, respectively, compared with basal values. HR and CO were decreased by 9.91% and 13.01%, respectively. Immediately after the maneuver (phase III), systolic and diastolic pressures were decreased by 5.05% and 6.24%, respectively, compared with those obtained in the phase II. HR and CO were elevated by 13.33% and 11.93%, respectively, compared to the levels of earlier phases. BPs were represented with overshoot in the phase IV, and recovered by baseline values about 20 sec after VM. Conclusion: These results demonstrated that hemodynamic changes are variable in the event of VM even in healthy humans. It will be valuable to accumulate more quantitative hemodynamic information in special populations such as the elderly and the patients with cardiovascular problems.

• Journal of Sensor Science and Technology
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• v.19 no.1
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• pp.8-16
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• 2010

This research proposes measuring of BCG(ballistocardiogram) to monitor heart activities in a non-constrained environment, at home or work. Unlike with ECG, measuring BCG does not require the attachment of leads on the subject's body and allows signal measuring in a non-constrained state. It enables effective long-term monitoring of cardiac conditions. In this study a chair type BCG measurement system to continuous monitor the activity of the heart is implemented. The instrument consists of upper petal and ready for press of chair load cell sensor is attached to measure the change of the object's weight. In order to extract the output ballistic signal from the weight and force sensor signals. Beside the signal processing circuit for the digital conversion, the ballistic signal is detected using DAQ equipment. Signal processing algorithm including wavelet transforms for noise cancellation, template matching for normalization and peak detection in BCG is developed. ECG and BCG were concurrently measured to evaluate the performance of the system, and comparing the characteristics of the two signals verified the possibility of the system in non-constrained and nonconscious health monitoring.

• Journal of Chest Surgery
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• v.21 no.6
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• pp.979-983
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• 1988

Calcium channel blockers may prevent myocardial injury during cardioplegia and reperfusion. This study was done to evaluate the effects of diltiazem cardioplegia on myocardial protection during ischemic arrest and recovery of myocardial function after reperfusion. Four formulations of crystalloid cardioplegic solutions, GIK solution[group I, n=12], diltiazem[lug/ml GIK] in GIK solution[group II, n=7], ],diltiazem[2ug/ml GIK] in GIK solution[group III, n=6] and diltiazem[4ug/ml GIK] in GIK solution[group IV, n=6] were compared in isolated working rat heart subjected to a long period [2 hours] of hypothermic arrest with multi-dose infusion. Diltiazem cardioplegia[group II, III and IV]was found to be superior in nearly all aspects. Diltiazem cardioplegia showed faster recovery of regular rhythm and lower incidence of ventricular fibrillation than group I did. In comparing mechanical function in all experimental hearts, the mean postischemic recoveries of aortic flow, cardiac output, peak aortic pressure, stroke volume and stroke work[expressed as a percentage of its preischemic control] were significantly greater in group II, III and IV[diltiazem cardioplegia] than in group I. The infused amount of cardioplegic solution was more increased by the addition of diltiazem to GI K solution. [p < 0.01] Creatine kinase leakage tended to be lower in hearts receiving diltiazem cardioplegia, especially in group III and IV[p<0.05] than in those receiving GIK solution only[group I]. Diltiazem cardioplegia results in the increased flow of cardioplegic solution and the decreased ischemic injury of myocardium during ischemic arrest and the improved recovery of myocardial function after reperfusion, and a dose-response relation must be established before clinical use.

• Journal of Chest Surgery
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• v.18 no.1
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• pp.79-85
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• 1985

The effect of graded increments in positive end-expiratory pressure [PEEP] on hemodynamics required to ventilate 8 critically ill patients is reported. Acute respiratory insufficiency was a cause of death in only one patient of drug inoxication among the 8 patients studied. The cardiac output was not changed significantly after the increment of PEEP to the level of 20 cm H2O. The heart rate was increased significantly from 15 cm H2O PEEP [P<0.01] as compared to 0 cm H2O PEEP; and the stroke volume was decreased significantly from 15 cm H2O PEEP [P<0.05]. The blood pressure was not affected at any level of PEEP, but the pulmonary artery pressure was elevated significantly at 10 cm H2O PEEP [P<0.01]. The right ventricular transmural filling pressure was not affected at the level of 10 cm H2O PEEP, but from 15 cm H2O PEEP it was increased significantly. With the increment of PEEP, the left ventricular stroke work index was decreased slightly; and at 20 cm H2O PEEP, it was decreased significantly. The right ventricular stroke work index was increased only at 10 cm H2O PEEP. The systemic vascular resistance was decreased significantly from 15 cm H2O PEEP [P<0.01].

• Journal of Chest Surgery
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• v.23 no.2
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• pp.253-259
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• 1990

Between January, 1970 and August, 1989, a total of 81 patients whose age were more than 20 years of life, received total correction for tetralogy of Fallot. This report analyzed 70 patients among them and excluded the remaining 11 patients whose clinical data could not be found. Their mean age was 25.750.39 years[range 20 \ulcorner50]. The clinical manifestations were cyanosis and clubbing [64 pts], frequent URI[40 pts], anoxic spell [19 pts], infective endo-carditis[4 pts], brain abscess[3 pts], pulmonary tuberculosis[3 pts] and CHF, chest tightness, nephrotic syndrome, left hemiplegia, and tamponade. The types of right ventricular outflow tract obstruction were combined[46 pts], pure infundibular [21 pts] and pure valvular[3 pts]. Associated cardiovascular anomalies were PFO [27 pts], ASDi8 pts], LSVC[8 pts], aortic regurgitation [5 pts], right aortic arch, coronary artery anomalies, PDA and dextrocardia. Hospital mortality was 5.7%. The causes of death ware low cardiac output [2 pts], aggravation of CRF[1 pts] and brain damage[1 pts]. There was one late death because of residual intracardiac shunt and congestive heart failure. During the follow-up period, 16 patients were lost and the remaining 49 patients were asymptomatic and leading normal lives. Residual intracardiac shunt was detected in 5 patients with radionuclide single pass study but all of them had Qp / Qs ratio less than 1.5.

• Journal of Chest Surgery
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• v.24 no.2
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• pp.115-122
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• 1991

From April 1986 to December 1989, 25 infants under the age of 12 months with tetralogy of Fallot were operated on. Age ranged from 3 to 12 months[mean 8.9$\pm$4.9 months] and mean body weight was 7.8$\pm$ 2.6kg. All the patients were deeply cyanotic, 12 of them experienced anoxic spell. Transannular patch was laid down in 19 patients, in 7 of them monocuspid patch was utilized. Postrepair P RV/LV was measured at operation room in 17 patients[mean 0.48$\pm$0. 14]. Hospital mortality was 20Yo. Causes of deaths include right ventricular failure and low cardiac output. The mortality was closely related with patient`s age and body surface area at operation. Also higher mortality was noticed in patients having major associated anomaly or previous palliative operation, preoperative management with propranolol and transannular repair. 18 patients were followed up for 12 to 50 months with a mean follow-up time of 24 months after operation. There were no late deaths and late ventricular arrhythmia or congestive heart failure was not detected as yet. Redo operation was performed in one case because of residual pulmonic stenosis. Considering several advantages of early primary repair, primary repair of symptomatic infants with tetralogy of Fallot should be encouraged despite somewhat high mortality rate as yet and better results could be anticipated along with improvement of myocardial protection method and postoperative care.