• Title/Summary/Keyword: Carboxyatractyloside

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A case report of cocklebur poisoning in Hanwoo (Korean native cattle) (한우에서 발생한 도꼬마리 중독 증례)

  • Jun, Kyoungah;Lee, DongEun;Jeong, DaeEun
    • Korean Journal of Veterinary Service
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    • v.44 no.2
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    • pp.113-117
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    • 2021
  • Cocklebur poisoning in livestock can cause sudden death, with clinical signs include depression, inappetite, blindness, reluctance to move, hypersensitivity, ataxia and coma. The cause of cocklebur poisoning is ingestion of cocklebur sprout or seed, which contains carboxyatractyloside. In December 2020, a 47 month-old Hanwoo suddenly developed ataxia, and died after several hours. Hay mixed cocklebur seeds was fed to Hanwoo for 4 days before the symptoms. At autopsy, petechia and ecchymosis were seen on serous membrane of rumen and intestines. Peritoneal cavities contained a yellowish fluid and, hypoglycemia (Glu <20 mg/dL) was measured in blood test result. Microscopic lesions were karyolysis of centriloular hepatocyte and hemorrhage. Based on autopsy, blood and histopathological test, we diagnosed this case as cocklebur poisoning in Hanwoo.