• 제목/요약/키워드: Carbon pretreatment

검색결과 271건 처리시간 0.028초

$CC1_4$의 간장독작용(肝臟毒作用)에 미치는 Thyroxine의 영향(影響) (Influence of Thyroxine on the Hepatotoxicity of Carbon Tetrachloride)

  • 홍기성;천연숙
    • 대한약리학회지
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    • 제16권2호
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    • pp.31-38
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    • 1980
  • Calvert et al. formulated the hypothesis that carbon tetrachloride ($CCl_4$) acted on the central nervous system to produce and intensify sympathetic discharge which resulted in anoxic necrosis of the liver. Recknagel suggested that the essential feature of $CCl_4$ hepatotoxicity depended on the cleavage of it to $CCl_3$(free radical) and the peroxidative decomposition of cytoplasmic membrane structural lipids. And there are many reports which show the increase of adrenergic activity in hyperthyroidism. In this paper, the influence of thyroxine on the hepatotexicity of carbon tetrachloride was investigated in mice. The results obtained were summarized as follows; 1) Hepatic total lipid and lipid peroxide contents were slightly decreased by L-sodium thyroxine injection(4mg/kg/day for 4days or 6days), but hepatic glycogen content was significantly decreased. 2) Hepatic total lipid and lipid peroxide contents and serum lactic dehydrogenase activity were significantly increased by $CCl_4$ (4 ml/kg single dose or triple dose: 4ml/kg/day for 3days), but hepatic glycogen content was significantly decreased. 3) The increase of hepatic total lipid and lipid peroxide contents and serum lactic dehydrogenase activity induced by $CCl_4$ were significantly inhitited by the pretreatment of thyroxine. 4) The decrease of hepatic glycogen induced by $CCl_4$ was not affected by the pretreatment of thyroxine.

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Evaluation of the Efficacy of Kochiae fructus Extract in the Alleviation of Carbon Tetrachloride-induced Hepatotoxicity in Rats

  • Kim Na-Young;Lee Jeong-Sook;Kim Seog-Ji;Park Myoung-Ju;Kim Seok-Hwan
    • Nutritional Sciences
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    • 제8권4호
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    • pp.212-218
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    • 2005
  • Hepatoprotective effects of the extract of Kochiae fructus (KF), a traditional oriental medicinal plant, were evaluated against carbon tetrachloride($CCl_4$)-induced liver damage in rats. Male Sprague-Dawley rats were divided into control, $CCl_4,\;CCl_4$ plus methanol extract of KF (KFM-$CCl_4$), and $CCl_4$ plus butanol extract of KF (KFB-$CCl_4$) groups. KFM and KFB were orally administered once a day (200 mg/kg body weight) for 14 days. A mixture of 0.2 mL/100 g body weight of $CCl_4$ in olive oil was injected at 30 minutes after the final administration of KFM and KFB. The KFB pretreatment resulted in a significant decrease in the serum transaminase and lactic dehydrogenase levels in the $CCl_4$-treated rats. The $CCl_4$ treatment significantly lowered the activities of glutathione, glutathione reductase (GR), glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-Px). However, pretreatment with KFM and KFB resulted in a significant increase in the glutathione, GR and GST levels. KFB increased the activities of SOD, catalase and GSH-Px, but KFM did not alter them. Pretreatment with KFM and KFB resulted in a significant decrease in the production of aminopyrine N-demethylase in the $CCl_4$-treated rats. KF extract would appear to contribute to alleviate the adveISe effect of $CCl_4$ treatment by enhancing the hepatic antioxidant defense system.

열 필라멘트 CVD법에 의한 다이아몬드 박막합성과 기판 사전처리의 영향 (Influence of Pretreatment of Substrate on the Formation of Diamond Thin Film by Hot Filament CVD)

  • 임경수;위명용;황농문
    • 한국재료학회지
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    • 제5권6호
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    • pp.732-742
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    • 1995
  • 다이아몬드 증착시 기판의 표면처리를 변화시켰을 때 다이아몬드의 핵생성 밀도에 미치는 영향에 대하여 연구하였다. 실험장치는 열 필라멘트 CVD 장치를 사용하였고, 반응가스로 메탄과 수소가스를 사용하였다. 기판의 표면 처리는 탄소 상을 기판에 증착시키는 방법, Soot에 의한 기판 표면처리, 혹연에 의한 기판 표면처리로 크게 3가지로 행하였다. 모든 경우에 핵생성 밀도가 증가하였으나 탄소 상을 증착시킨 경우와 soot에 의한 사전처리의 경우의 핵생성 밀도의 증가가 혹연에 의한 처리보다 더 현저하였다. 또한 탄소강의 증착의 경우 표면에 굴곡이 없는 매우 평탄하고 균일한 다이아몬드 막을 얻을 수 있었다. 사전증착처리 한 기판에 탄소 층을 형성시켰을 때 탄소 층과 기판과의 접착력이 약한 것을 이용하여 다이아몬드 막을 쉽게 분리시켜 free standing 다이아몬드 박막을 얻을 수 있음을 알았다.

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잠재적 이방성 핏치를 이용한 탄소성형체 제조 (Preparation of Carbon Solid from Dormant Mesophase Pitch without using a Binder)

  • 김제영;이성영;최재훈;박양덕
    • 한국세라믹학회지
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    • 제29권5호
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    • pp.396-402
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    • 1992
  • Carbon solid was prepared from dormant mesophase pitch (DMPP) without using a binder and its properties were characterized. DMPP powder was stabilized with air or nitric acid in pretreatment stage so that it might not soften in later heat ttreatment stage. Optimum sintering properties were obtained from carbon powder with 2.36∼2.38 of C/H atomic ratio and 1.27∼1.40 of C/O atomic ration in air stabilization. In nitric acid stabilization, optimum sintering properties were obtained when 20∼40 vol.% of nitric acid solution was used. Compressive strength increased up to 1200$^{\circ}C$ of heat treatment temperature, and the highest compressive strength and bulk density of carbon solid from DMPP were 3000 kgf/㎤, respectively. The optical properties of carbon solid obtained was fine mosaic structure. Carbon solid after graphitization showed the properties of hard carbon due to stabilization and its shore hardness was 120.

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VOCs 연소를 위한 자동차 폐촉매의 전처리 효과 (Pretreatment Effect of Waste Automotive Catalysts for VOCs Combustion)

  • 문정선
    • 한국대기환경학회지
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    • 제16권2호
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    • pp.191-198
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    • 2000
  • For a characterization of the pretreated waste automotive catalyst the following analysis techniques were applied : EA(Elemental Analysis) BET(Brunaure-Emmett-Teller) and ICP-AES(Inductively Coupled Plasma-Atomic Emission Spectrometry). The combustion activity of waste automotive catalyst was investigated for methanol acetaldehyde and toluene as model VOCs in a fixed bed reactor. carbon deposit amount was decreased with increasing catalyst showed a good catalytic activity for VOCs combustion at 40$0^{\circ}C$. Catalytic activity for methanol acetaldehyde and toluence combustion was very excellent and decreased with mileage. The catalytic activity of a waste automotive catalyst for methanol combustion increased after acid treatment. The acid effect of catalytic activity was summarized as follows: HNO3>HCI>H2SO4>CH3COOH. The waste automotive catalyst regenerated by the pretreatment method might have a excellent catalytic activity for VOCs combustion.

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막분리 공정을 이용한 SIES 전처리설비 개념 설계 (Conceptual Design of Pretreatment Process for SIES Using Membrane Process)

  • 이상진;양호연;신상운
    • 한국방사성폐기물학회:학술대회논문집
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    • 한국방사성폐기물학회 2003년도 가을 학술논문집
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    • pp.15-20
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    • 2003
  • 고리 2호기 선택성 이온교환시스템(SIES)은 운영 과정에서 본 설비에 유입되는 방사성 폐액에 함유된 부유물질과 기름 성분들에 의해 선택성 이온교환설비의 활성탄과 이온교환수지가 쉽게 오염되어 이온 형태의 방사성 핵종과 부식성 입자성 방사성 핵종인 Ag-110m의 제거가 불가능한 문제점이 대두되었다. 본 연구에서는 SIES로 유입되는 수질을 개선하기 위한 실험을 수행하여 설계 기초 자료를 확보하였고, SIES 전처리 설비의 정밀여과분리막과 나노분리막에 대한 각각의 모듈 설계를 수행하였다.

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생물처리를 이용한 상수원수의 전처리공정에 관한 비교연구 (Comparative Study on Biological Pretreatment Processes for Biologically Stable Drinking Water)

  • 우달식;남상호
    • 한국환경보건학회지
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    • 제22권4호
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    • pp.69-76
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    • 1996
  • Biological process have the potential to remove pollutants such as biodegradable organic fraction, $NH_3-N$, ABS, etc. that may be partially removed by conventional water treatment. This study was performed to evaluate four different processes of biological pretreatment as Biological Fluidized Bed(BFB), Biological Filter(BF), Rotating Biological Contactor(RBC) and Honey Comb(HC). In a given condition it proved out that BFB and BF are prospective biological pretreatment processes because they were the most effective on the removal of organic matter and ammonia. Preozonation of raw water for biological processes increased in biodegradable organic fraction about 10-40% with 0.425-0.85 mg $O_3/mg$ DOC.

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하천수 내 생물학적 안정성에 따른 유기물 특성변화와 오존산화기반 전처리 연구 (Biological stability in the ozone and peroxone pretreatment systems in river water)

  • 박세희;노진형;박지원;맹승규
    • 상하수도학회지
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    • 제32권2호
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    • pp.159-168
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    • 2018
  • Climate change is believed to increase the amount of dissolved organic matter in surface water, as a result of the release of bulk organic matter, which make difficult to achieve a high quality of drinking water via conventional water treatment techniques. Therefore, the natural water treatment techniques, such as managed aquifer recharge (MAR), can be proposed as a alternative method to improve water quality greatly. Removal of bulk organic matter using managed aquifer recharge system is mainly achieved by biodegradation. Biodegradable dissolved organic carbon (BDOC) and assimilable organic carbon (AOC) can be used as water quality indicators for biological stability of drinking water. In this study, we compared the change of BDOC and AOC with respect to pretreatment methods (i.e., ozone or peroxone). The oxidative pretreatment can transform the recalcitrant organic matter into readily biodegradable one (i.e., BDOC and AOC). We also investigated the differences of organic matter characteristics between BDOC and AOC. We observed the decreases in dissolved organic carbon (DOC) and the tryptophan-like fluorescence intensities. Liquid chromatographic - organic carbon detection (LC-OCD) analysis also showed the reduction of the low molecular weight (LMW) fraction (15% removed, less than 500 Da), which is known to be easily biodegradable, and the biopolymers, high molecular weight fractions (66%). Therefore, BDOC consists of a broad range of organic matter characteristics with respect to molecular weight. In AOC, low molecular weight organic matter and biopolymers fraction was reduced by 11 and 6%, respectively. It confirmed that biodegradation by microorganisms as the main removal mechanism in AOC, while BDOC has biodegradation by microorganism as well as the sorption effects from the sand. $O_3$ and $O_3+H_2O_2$ were compared with respect to biological stability and dissolved organic matter characteristics. BDOC and AOC were determined to be about 1.9 times for $O_3$ and about 1.4 times for $O_3+H_2O_2$. It was confirmed that $O_3$ enhanced the biodegradability by increasing LMW dissolved organic matter.

Hepatoprotective Effects of the Acteoside on Carbon tetrachloride Induced Liver damage in Mice

  • Lee, Kyung-Jin;Woo, Eun-Rhan;Choi, Chul-Yung;Jeong, Hye-Gwang
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.174.1-174.1
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    • 2003
  • The protective effects of acteoside, a phenylethanoid glycoside, on cabon tetrachloride-induced hepatotoxicity and the possible mechanisms involved in this protection were investigated in mice. Pretreatment with acteoside prior to the administration of carbon tetrachloride significantly prevented the increased serum enzymatic activities of alanine and aspartate aminotransferase in a dose-dependent manner. (omitted)

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