• 제목/요약/키워드: Carbon dioxide(dryice)

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페놀베타인 유도체합성 및 항암 활성검토: 프로토베르베린에서 C-환의 화학적 변환 (Synthesis of Phenolbetaine Derivatives and Their Anti-cancer Activity: Chemical Transformation of C-ring of Protoberberine)

  • 우성주;박예진;황순호;홍유화;이마세;김동현;김인종;김신규
    • 약학회지
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    • 제40권5호
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    • pp.487-490
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    • 1996

  • The 13-hydroxyberbine(1), derived from berberinephenolbetaine, has been derivatized to furnish a variety of compounds such as 13-oxoberbine(2), 13-thioberbine(3), 13-chloroberbi ne(4), 13-(2-methylaziridine)berbine(5) and 13-carbolactoneberbine(6). Antitumor activity of these compounds was tested.

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