• Archives of Pharmacal Research
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• 제27권6호
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• pp.670-675
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• 2004

Since the bitter taste of enrofloxacin apparently limit the patient compliance in the oral formulations of the antibacterial agent, the masking of the taste is essential for the improvement of the therapeutic effectiveness. Therefore, this study was carried out to examine the feasibility of taste masking of enrofloxacin by the retardation of its dissolution rate using the formation of complex between the drug and Carbopol. The complexation between Carbopol and enrofloxacin was confirmed by turbidity, UV spectrophotometry, wide angle X-ray diffraction, and differential scanning calorimetry. The enrofloxacin content in the complexes was 34％ （Carbo-enrofloxacin complex I） and 57％ （Carbo-enrofloxacin complex II） depending on the prepara-tion method. The dissolution rate of enrofloxacin from the complex increased as the pH was reduced. The dissolution rate of enrofloxacin from the Carbo-enrofloxacin complex I was significantly lower than that of the enrofloxacin powder. Therefore, these observations suggest that Carbo-enrofloxacin complex I can be used to mask the taste of enrofloxacin.

• 한국농림기상학회지
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• 제7권1호
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• pp.15-27
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• 2005

육상생태계의 물/탄소 순환은 기후변화의 원인과 진행 과정 그리고 결과를 예측하는데 필수적인 기초 자료이다. CarboKorea와 HydroKorea 연구에서는 한반도의 대표적인 지형과 식생 유형에 적합한 물/탄소 순환 해석과 실황예보를 위한 기술개발을 목표로, 안정동위원소를 이용해 물/탄소 순환의 구성요소를 성인적으로 세분하는 연구를 수행하고 있다. 본 논문에서는 이러한 안정 동위원소 연구가 국내 생태계의 물과 탄소 순환연구에 적극적으로 활용될 수 있도록 하기 위해 그 이론적 배경과 광릉 소유역의 연구 사례를 소개하였다. 시간과 공간 규모의 확장을 가능케 하는 안정 동위원소 연구는 다양한 관련분야의 연구와 함께 한반도 육상생태계의 물/탄소 순환과정에 대한 보다 정량적인 해석을 가능하게 함으로써 기후변화와 관련하여 제기되고 있는 당면한 과학적, 사회경제적 요구에 부흥할 수 있는 과학적 기반을 구축하는데 기여할 것으로 기대된다.

• Journal of Forest and Environmental Science
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• 제34권1호
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• pp.57-60
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• 2018

Great cormorant (Phalacrocorax carbo) have been growing on a large scale since they settled on Jokja Island in Lake Paldang in 2010. In 2017, 827 breeding nests were found in Jokja Island and the breeding success rate was $2.60{\pm}0.23$ per nest. Nestling tree did not show any specificity for the species and was severely damaged. As the nesting materials for cormorants, branches and leaves, which were easy to come by around the island, were used. Most of their prey were fish in Lake Paldang. The population the great cormorants showed high breeding success rate, indicating that Jokja Island was a good site for breeding. Thus, it shows that continuous research for them needs to be done.

• 약학회지
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• 제43권3호
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• pp.328-333
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• 1999

In order to develop selective and competitive and competitive antagonist at the $P2Y_1$ receptor a carbocyclic oxetanocin bisphosphate derivative (7) was synthesized as a bioisostere of the lead, MRS 2179. The synthesis was started from ketene diethylacetal (1) and completed in 6 steps.

• Journal of Ecology and Environment
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• 제43권3호
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• pp.282-288
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• 2019

We investigated the changes in the population size and inter-specific space usage for breeding in mixed breeding sites of the great cormorant (Phalacrocorax carbo), grey heron (Ardea cinerea), great egret (Ardea alba modesta) and intermediate egret (Egretta intermedia) in Gammul-myeon, Goesan-gun, Chungcheongbuk-do, South Korea, in 2016-2017. These species bred in two adjacent habitats (site A and site B). The number of breeding pairs of all species and the size of the breeding area at site B increased in 2017. In 2017, great cormorants at site B occupied the breeding sites previously occupied by the other species in 2016, while the grey heron and great egret occupied the sites around the great cormorant breeding site. The heights of nest trees and nests of great cormorant and grey heron did not differ temporally, but these heights in site B were significantly higher than those in site A for great cormorants. For great egrets, these greatly decreased in site B in 2017. Thus, the great cormorant either moved to favourable nest sites for breeding success or selected nest sites used by the herons in the previous year. Further studies of these two possibilities are necessary.

• 유기물자원화
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• 제25권4호
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• pp.41-50
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• 2017

점도, 임펠러 종류, 소비전력 등에 의해 영향을 받는 생물학적 폐기물 처리시설 및 에너지 생산 플랜트에서 적절한 교반 시스템의 설계는 필수적이다. 본 연구에서는 적절한 교반 시스템의 설계를 위해 음식물류폐기물을 이용하여 다양한 조건(운전 pH 및 농도)에서의 수소발효 시 유변학적 특성의 변화를 조사한 후, 이를 기반으로 교반강도를 설계하였다. 운전 pH에 따른 수소발효 실험에서 수소전환율은 $0.51{\sim}1.77mol\;H_2/mol\;hexose_{added}$였고, 가장 높은 수소전환율은 운전 pH 5.5에서 나타났다. 발효액은 전단속도가 증가함에 따라 점도가 감소하는 Shear thinning 거동을 보였다. 탄수화물이 분해되면서 발효 이후 점도는 초기 점도보다 감소하는 경향을 보였으나, 운전 pH의 변화에 따른 발효액의 점도 변화는 크지 않았다. 탄수화물 농도 10~50 g Carbo. COD/L에서 수소전환율은 $1.40{\sim}1.86mol\;H_2/mol\;hexose_{added}$로 운전 pH 조건이 수소전환율에 미친 영향과 비교했을 때 큰 차이는 없었다. 발효액의 Zero viscosity와 Infinite viscosity는 탄수화물 농도에 따라 각각 $10.4{\sim}346.2mPa{\cdot}s$와 $1.7{\sim}5.3mPa{\cdot}s$로 나타났는데, 10 g Carbo. COD/L와 20 g Carbo. COD/L에서 발효액의 점도 값은 거의 차이가 없었다. 실험 결과에 기초하여 교반강도를 설계한 결과, 기질농도 30 g Carbo. COD/L의 수소발효 초기 및 발효 후 교반강도는 각각 26.0, 10.0 rpm으로 약 2.5배 정도의 교반강도를 줄임으로써 에너지를 절약할 수 있을 것으로 사료된다.

• 한국농림기상학회지
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• 제9권2호
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• pp.71-74
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• 2007

• 타이어
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• 통권96호
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• pp.21-29
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• 1981

현재 미국에서는 카본블랙 시장에 영향을 주는 많은 변화가 일어나고 있다. 즉, 카본블랙의 원료유 가격인상, 종류별 사용량의 변화, 가격인상 압력 등, 이 모든 요인들이 앞으로의 카본블랙 공업의 방향을 결정하게 될 것이다.

• 한국주조공학회지
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• 제14권5호
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• pp.455-463
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• 1994

Aluminum matrix composites reinforced by fine steel wires were fabricated by squeeze casting process. Preforms made of fine steel wires were prepared with different surface conditions, namely uncoated(TN), carbo-nitriding treated(TT), and brass coated(TA). Squeeze casting were performed under the pressure of $1500kg/cm^2$ for 3min. during solidification, and pouring temp. of the melt being $750^{\circ}C$ and the steel mold being preheated at $250^{\circ}C$. Microstructural characteristics were evaluated, particularly concerned with the effect of the surface conditions of the preforms. The results obtained from this study are like these. TN specimens show partially non-wetted regions, due to easy formation of oxides on the surface of the fine steel wires. TT specimens show no interfacial reaction between the steel wires and the aluminum alloy matrix, possibly due to the formation of carbo-nitrided zone on the surface of the steel wires. TA specimens show excellent wettabillity between the reinforced steel wires and the aluminum alloy matrix and very thin interfacial zone is formed between them. During the solution hardening treatment of TA specimens, thickness of the interfacial reaction zones were increased with the solution treating time. TA specimens show typical ductile fracture in tensile test, but TT specimens show brittle fracture possibly due to the formation of the brittle hard surface on the steel wires during carbo-nitriding treatments. TA specimens which were reinforced with 40 vol.% of the fine steel wires exhibit high tensile strength of $77.1kgf/mm^2$ and impact value of $8.1kgf-m/cm^2$.

• 한국농림기상학회지
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• 제7권1호
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• pp.4-14
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• 2005

CarboKorea and HydroKorea are the domestic projects aiming to improve our understanding of carbon and water cycles in a typical Korean forest located in a complex terrain with a watershed connected to large rivers. The ultimate goal is to provide a nowcasting of these cycles for the whole Peninsula. The basic strategy to achieve such goal is through the inter- and multi-disciplinary studies that synthesize the in-situ field observation, modeling and remote sensing technology. The challenge is the fact that natural ecosystems are nonlinear and heterogeneous with a wide range of spatio-temporal scales causing the variations of mass and energy exchanges from a leaf to landscape scales. Our paradigm now shifts from temporal variation at a point to spatial patterns and from spatial homogeneity to complexity of water and carbon at multiple scales. Yet, a large portion of our knowledge about land-atmosphere interactions has been established based on tower observations, indicating that the development of scaling logics holds the key to the success of CarboKorea and HydroKorea. Here, we review the pioneering work of FIFE (First ISLSCP Field Experiment) on scaling issues in a temperate grassland and discuss the lessons from it for the application to Gwangneung forest site.