• 센서학회지
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• 제13권5호
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• pp.378-382
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• 2004

A micromachined fluidic structure for the introduction of liquid samples into a chip-based sensor array composed of individually addressable polymeric microbeads has been developed. The structure consists of a separately attached cover glass, a single silicon chip having micromachined channels and microbead storage cavities, and a glass carver. In our sensor array, transduction occurs via colorimetric and fluorescence changes to receptors and indicator molecules that are covalently attached to termination sites on the polymeric microbeads. Data streams are acquired for each of the individual microbeads using a CCD. One of the key parts of the structure is a passive fluid introduction system driven only by capillary force. The velocity of penetration of a horizontal capillary for the device having a rectangular cross section has been derived, and it is quite similar to the Washburn Equation calculated for a pipe with a circular cross section having uniform radius. The test results show that this system is useful in a ${\mu}$-TAS and biomedical applications.

• 대한기계학회논문집B
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• 제30권2호
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• pp.110-116
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• 2006

A syringe pump or a device using high electric voltage has been used for controlling flows inside a LOC (lab-on-a-chip). Compared to LOC, however, these microfluidic devices are large and heavy that they are burdensome for a portable ${\mu}-TAS$ (micro total analysis system). In this study, a new flow control technique employing pressure regulators and pressure chambers was developed. This technique utilizes compressed air to control the micro-scale flow inside a LOC, instead of a mechanical actuator or an electric power supply. The pressure regulator controls the output air pressure by adjusting the variable resistor attached. We checked the feasibility of this system by measuring the flow rate inside a capillary tube of $100{\mu}m$ diameter in the Re numbers ranged from 0.5 to 50. In addition, the performance of this flow control system was compared with that of a conventional syringe pump. The developed flow control system was found to show superior performance, compared with the syringe pump. It maintains automatically the: air pressure inside a pressure chamber whether the flow inside the capillary tube is on or off. Since the flow rate is nearly proportional to the resistance, we can control flow in multiple microchannels precisely. However, the syringe pump shows large variation of flow rate when the fluid flow is blocked in the microchannel.

• 대한기계학회논문집B
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• 제34권1호
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• pp.77-82
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• 2010

소형분석시스템에서 미세채널의 상판이 제거되면 상판에 의한 빛 에너지 손실이 대폭 감소되어 광학측정법으로 대상을 분석할 때 장점을 갖는다. 본 연구에서는 상판이 없는 사각단면 미세채널 내 액체유동을 이해하려는 목적으로 실험과 전산유체역학 해석을 수행하였다. 개방형 사각단면 미세채널에서 입자추적기법으로 유속을 측정하였고, 채널의 단면적 변화에 따른 모세관 유동현상을 이론적으로 해석하였다. 단면의 너비와 높이가 각각 20 ${\mu}m$로 제작된 미세채널의 주입부에 물을 떨어뜨렸을 때 물은 오직 모세관 힘에 의해 미세채널을 따라 이동하였다. 액체의 젖음현상에 영향을 미치는 중요한 유동 파라미터는 채널의 크기와 표면장력, 점성 등으로 볼 수 있으며, 미세채널에서 액체 유동을 조절하는데 이용될 수 있다.