• Journal of the Korean Geotechnical Society
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• v.19 no.3
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• pp.33-38
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• 2003

Marine sediment capping is a technique where clean sand is placed over contaminated sediment to reduce the migration of contaminants to the environment. The design of in-situ caps placed over marine sediment must take into consideration the self-weight consolidation of the cap and the consolidation of the sediment as a result of adding the cap layer. Centrifuge tests were adopted to simulate the effects of consolidation settlement of capped marine sediment caused by the placement of a clean sand layer. The modeling of models technique was utilized to verify the correct modeling procedures used in this study. Two centrifuge tests were conducted with the same boundary conditions at different gravitational accelerations of 100 g and 50 g. There was good agreement between these tests. It can be concluded that the centrifuge experiment is able to model consolidation settlement of capped marine sediment.

• Journal of the Korean Society of Radiology
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• v.12 no.7
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• pp.801-806
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• 2018

Germanium crystals have a dead layer that causes efficiency deterioration because the layer is not useful for detection but strongly weakens the photons. Thus, when the data provided by the manufacturer is used in the detector simulation model, there is a slight difference between the calculated efficiency and the measured efficiency.The shape and dimensions of the high purity germanium (HPGe) detector were determined by CT scans to accurately characterize the shape for the Monte Carlo roll simulation. It is found that the adjustment of the dead layer is a good match with the relative deviation of ${\pm}3%$ between the measurement efficiency and the simulation efficiency at the energy range of 50 - 1500 keV. Simulation data were compared by varying the thickness of the dead layer. The new Monte Carlo simulations were compared with the experimental results to obtain new blank layer thicknesses. The difference in dead layer results for the 1.5 mm thick end cap simulation model in 1.4 and 1.6 mm thick End Cap simulation models was a systematic error due to the accuracy of the end cap dimensions. After considering all errors including statistical errors and systematic errors, the thickness of the detector was calculated as $1.02{\pm}0.14mm$. Therefore, it was confirmed that the increase in the thickness of the dead layer causes the effect to be effected on the efficiency reduction.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.41 no.11
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• pp.53-59
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• 2004

This paper proposes an efficient method for computing the 3-dimensional capacitance of complex structures. The proposed method is based on applying numerical 2-dimensional capacitance extraction formula for 3-dimensional interconnect models. This method improves the extraction efficiency 952 times while compromising the accuracy within 1.8 percentage of maximal relative error, compared with the results of Fastcap program for various 3-D models. The proposed method can be used efficiently to extract electrical parameters of on/off-chip interconnects in VLSI systems.

• Journal of Cadastre & Land InformatiX
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• v.47 no.2
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• pp.159-174
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• 2017

The long-term imbalances between supply and demand in office market can weaken urban growth since excessive supply of offices led to office market instability and excessive demand of offices weakens growth of urban industry. Recently, there have been a lot of new large-scale supplies, which increased volatility in Seoul office market. Nevertheless, new supply of Seoul office has not been fully examined. Given this, the focus of this article was on confirming the influences of profitability, replacement cost, and demand on new office supplies in Seoul. In examining those influences, another focus was on their relative influences over time. For these purposes, we analyzed quarterly data of Seoul office market between 2003 and 2015 using a vector error correction model (VECM). As a result, in terms of the influences on the current new supply, the impact of supply before the first quarter was negative, while that of office employment before the first quarter was positive. Also, that of interest rate before the second quarter was positive, while those of cap rate before the first quarter and cap rate before the second quarter were negative. Based on the findings, it is suggested that prediction models on Seoul offices need to be developed considering the influences of profitability, replacement cost, and demand on new office supplies in Seoul.

• Interaction and multiscale mechanics
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• v.3 no.1
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• pp.55-79
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• 2010

The effect of soil-structure interaction on a single-storey, two-bay space frame resting on a pile group embedded in the cohesive soil (clay) with flexible cap is examined in this paper. For this purpose, a more rational approach is resorted to using the finite element analysis with realistic assumptions. Initially, a 3-D FEA is carried out independently for the frame on the premise of fixed column bases in which members of the superstructure are discretized using the 20-node isoparametric continuum elements. Later, a model is worked out separately for the pile foundation, by using the beam elements, plate elements and spring elements to model the pile, pile cap and soil, respectively. The stiffness obtained for the foundation is used in the interaction analysis of the frame to quantify the effect of soil-structure interaction on the response of the superstructure. In the parametric study using the substructure approach (uncoupled analysis), the effects of pile spacing, pile configuration, and pile diameter of the pile group on the response of superstructure are evaluated. The responses of the superstructure considered include the displacement at top of the frame and moments in the columns. The effect of soil-structure interaction is found to be quite significant for the type of foundation considered in the study. Fair agreement is observed between the results obtained herein using the simplified models for the pile foundation and those existing in the literature based on a complete three dimensional analysis of the building frame - pile foundation - soil system.

• Journal of the Society of Naval Architects of Korea
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• v.48 no.1
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• pp.42-48
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• 2011

To define ice as a solid material, mathematical and physical characteristics and their application examples are investigated for several materials' yield functions which include isotropic elastic, isotropic elastic-plastic, classical Drucker-Prager, Drucker-Prager Cap, Heinonen's elliptic, Derradji-Aouat's elliptic, and crushable foam models. Taking into account brittle failure mode of ice subject to high loading rate or extremely low temperature, isotropic elastic model can be better practicable than isotropic elastic-plastic model. If a failure criterion can be properly determined, the elastic model will provide relatively practicable impact force history from ice-hull interactions. On the other hand, it is thought that the soil models can better predict the ice spalling mechanism, since they contain both terms of shear stress-induced and hydrostatic stress-induced failures in the yield function.

• Membrane and Water Treatment
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• v.7 no.5
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• pp.403-416
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• 2016

The possibility of using carica papaya leaf powder for removal of copper from wastewater as a low cost adsorbent was explored. Different parameters that affect the adsorption process like initial concentration of metal ion, time of contact, adsorbent quantity and pH were evaluated and the outcome of the study was tested using adsorption isotherm models. A maximum of 90%-94.1% copper removal was possible from wastewater having low concentration of the metal using papaya leaf powder under optimum conditions by conducting experimental studies. The biosorption of copper ion was influenced by pH and outcome of experimental results indicate the optimum pH as 7.0 for maximum copper removal. Copper distribution between the solid and liquid phases in batch studies was described by isotherms like Langmuir adsorption and Freundlich models. The adsorption process was better represented by the Freundlich isotherm model. The maximum adsorption capacity of copper was measured to be 24.51 mg/g through the Langmuir model. Pseudo-second order rate equation was better suited for the adsorption process. A dynamic mode study was also conducted to analyse the ability of papaya leaf powder to remove copper (II) ions from aqueous solution and the breakthrough curve was described by an S profile. Present study revealed that papaya leaf powder can be used for the removal of copper from the wastewater and low cost water treatment techniques can be developed using this adsorbent.

• Journal of Ocean Engineering and Technology
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• v.28 no.2
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• pp.147-151
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• 2014

This research presents a method for the initial structural design of a multi-megawatt wind turbine blade. The structural data for a 2-MW blade were applied as the blade structural characteristic data of the reference blade. Tenkinds of blade models were newly designed by replacing the spar cap axial GRRP with a GFRP and CFRP These terms should be defined. at different orientations. The axial stiffness coefficients of the newly designed models were made equal to the coefficient of the reference blade. The required numbers of layers in each section of blades were calculated, and the lay-up designs were based on these numbers. Verification results showed that the design method that used the structural data of the reference blade was appropriate for the initial structural design of a wind turbine blade.

• International Journal of Concrete Structures and Materials
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• v.8 no.3
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• pp.239-249
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• 2014

In this paper, the analysis of a numerical study of pile-soil interaction subjected to axial and lateral loads is presented. An analysis of the composite pile-soil system was performed using the finite difference (FD) software LPILE. Two three dimensional, finite element (FE) models of pile-soil interaction have been developed using Abaqus/Cae and SAP2000 to study the effect of lateral loading on pile embedded in clay. A lateral displacement of 2 cm was applied to the top of the pile, which is embedded into the concrete pile cap, while maintaining a zero slope in a guided fixation. A comparison between the bending moments and lateral displacements along the depth of the pile obtained from the FD solutions and FE was performed. A parametric study was conducted to study the effect of crucial design parameters such as the soil's modulus of elasticity, radius of the soil surrounding the pile in Abaqus/Cae, and the number of springs in SAP2000. A close correlation is found between the results obtained by the FE models and the FD solution. The results indicated that increasing the amount of clay surrounding the piles reduces the induced bending moments and lateral displacements in the piles and hence increases its capacity to resist lateral loading.

• Toxicological Research
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• v.8 no.2
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• pp.343-357
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• 1992

Tumor necrosis factor-${\alpha}$(TNF), a polypeptide hormone secreted primarily by activated macrophages, was originally identified on the basis of its ability to cause hemorrhagic necrosis and tumor regression in vivo. Subsequently, TNF has been shown to be an important component of the host responses to infection and cancer and may mediate the wasting syndrome known as cachexia. These systemic actions of TNF are reflected in its diverse effects on target cells in vitro. TNF initiates its diverse cellular actions by binding to specific cell surface receptors. Although TNF receptors have been identified on most of animal cells, regulation of these receptors and the mechanisms which transduce TNF receptor binding into cellular responses are not well understood. Therefore, in the present study, the mechanisms how TNF receptors are being regulated and how TNF receptor binding is being transduced into cellular responses were investigated in rat liver plasma membranes (PM) and ME-180 human cervical carcinoma cell lines. $^{125}I$-TNF bound to high ($K_d=1.51{\pm}0.35nM$)affinity receptors in rat liver PM. Solubilization of PM with 1% Triton X-100 increased both high affinity (from $0.33{\pm}0.04\;to\;1.67{\pm}0.05$ pmoles/mg protein) and low affinity (from $1.92{\pm}0.16\;to\;7.57{\pm}0.50$ pmoles/mg protein) TNF binding without affecting the affinities for TNF, suggesting the presence of a large latent pool of TNF receptors. Affinity labeling of receptors whether from PM or solubilized PM resulted in cross-linking of $^{125}I$-TNF into $M_r$ 130 kDa, 90 kDa and 66kDa complexes. Thus, the properties of the latent TNF receptors were similar to those initially accessible to TNF. To determine if exposure of latent receptors is regulated by TNF, $^{125}I$-TNF binding to control and TNF-pretreated membranes were assayed. Specific binding was increased by pretreatment with TNF (P<0.05), demonstrating that hepatic PM contains latent TNF receptors whose exposure is promoted by TNF. Homologous up-regulation of TNF receptors may, in part, be responsible for sustained hepatic responsiveness during chronic exposure to TNF. As a next step, the post-receptor events induced by TNF were examined. Although the signal transduction pathways for TNF have not been delineated clearly, the actions of many other hormones are mediated by the reversible phosphorylation of specific enzymes or target proteins. The present study demonstrated that TNF induces phosphorylation of 28 kDa protein (p28). Two dimensional soidum dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE) resolved the 28kDa phosphoprotein into two isoforms having pIs of 6.2 and 6.1. The pIs and relative molecular weight of p28 were consistent with those of a previously characterized mRNA cap binding protein. mRNA cap binding proteins are a class of translation initiation factors that recognize the 7-methylguanosine cap structure found on the 5' end of eukaryotic mRNAs. In vitro, these proteins are defined by their specific elution from affinity columns composed of 7-methylguanosine 5'-triphosphate($m^7$GTP)-Sepharose. Affinity purification of mRNA cap binding proteins from control and TNF treated ME-180 cells proved that TNF rapidly stimulates phosphorylation of an mRNA cap binding protein. Phosphorylation occurred in several cell types that are important in vitro models of TNF action. The mRNA cap binding protein phosphorylated in response to TNF treatment was purifice, sequenced, and identified as the proto-oncogene product eukaryotic initiation factor-4E(eIF-4E). These data show that phosphorylation of a key component of the cellular translational machinery is a common early event in the diverse cellular actions of TNF.