• Molecules and Cells
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• 제38권11호
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• pp.1007-1012
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• 2015

EphA7 is a key molecule in regulating the development of the dien- and mesencephalon. To get insight into the mechanism of how EphA7 gene expression is regulated during the dorsal specification of the dien- and mesencephalon, we investigated the cis-acting regulatory sequence driving EphA7 to the dorsal midline of the dien- and mesencephalon. Transgenic LacZ reporter analysis, using overlapping EphA7 BACs, was used to narrow down the dorsal midline-specific enhancer, revealing the 25.3 kb genomic region as the enhancer candidate. Strikingly, this genomic DNA was located far downstream of the EphA7 transcription start site, +302.6 kb to +327.9 kb. Further enhancer mapping, using comparative genomic analysis and transgenic methods, showed that the 187 bp genomic DNA alone, approximately 305 kb downstream of the EphA7 transcription start site, was sufficient to act as the dorsal midline-specific enhancer of EphA7. Importantly, our results indicate that the 187 bp dorsal midline-specific enhancer is critically regulated by homeobox transcription factors during the development of the dien- and mesencephalon.

• 대한공간정보학회지
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• 제10권3호
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• pp.79-87
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• 2002

항공사진에 포함된 사진 지표의 방사 및 기하 특성을 이용하여 지표의 중심 위치를 자동으로 인식하기 위한 접근 방법을 제안한다. 방사 특성에 기반을 둔 전략에 근거하여, 입력된 영상을 이진화한 다음 형태 연산자를 적용시켜 사진 지표가 있는 후보 영역을 추출한다. 기하 특성에 기반을 둔 전략에 근거하여 ${\bigtriangledown}^G$ 필터링과 대칭성 강조 필터링을 적용시킨 후, 대칭이 가장 강하게 나타나는 위치인 지표의 중심 위치를 구한다. 사진 지표를 포함하고 있는 66매의 영상에 대한 평가 결과 중심 위치가 수동으로 관측한 결과와 비교할 때 1 화소 정도의 차이로 얻어질 수 있었다.

• Journal of Ubiquitous Convergence Technology
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• 제1권1호
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• pp.9-17
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• 2007

Feature based stereo matching is an effective way to perform 3D building reconstruction. However, in urban scene, the cluttered background and various building structures may interfere with the performance of building reconstruction. In this paper, we propose a novel method to robustly reconstruct buildings on the basis of rectangle regions. Firstly, we propose a multi-scale linear feature detector to obtain the salient line segments on the object contours. Secondly, candidate rectangle regions are extracted from the salient line segments based on their local information. Thirdly, stereo matching is performed with the list of matching line segments, which are boundary edges of the corresponding rectangles from the left and right image. Experimental results demonstrate that the proposed method can achieve better accuracy on the reconstructed result than pixel-level stereo matching.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1995년도 하계학술대회 논문집 B
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• pp.591-593
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• 1995

Artificial neural network based pattern recognition method is one of the most probable candidate for on-line power system transient stability analysis. Especially, Kohonen layer is an adequate neural network for the purpose. Each node of Kehonen layer competes on the basis of which of them has its clustering center closest to an input vector. This paper discusses Kohonen's LVQ(Learning Victor Quantization) and points out a defection of the algorithm when applied to the transient stability analysis. Only the clustering centers located near the decision boundary of the stability region is needed for the stability criterion and the centers far from the decision boundary are redundant. This paper presents a new algorithm ratted boundary searching algorithm II which assigns only the points that are near the boundary in an input space to nodes or Kohonen layer as their clustering centers. This algorithm is demonstrated with satisfaction using 4-generator 6-bus sample power system.

• Genomics & Informatics
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• 제12권4호
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• pp.225-230
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• 2014

Platelets are derived from the fragments that are formed from the cytoplasm of bone marrow megakaryocytes-small irregularly shaped anuclear cells. Platelets respond to vascular damage, contracts blood vessels, and attaches to the damaged region, thereby stopping bleeding, together with the action of blood coagulation factors. Platelet activation is known to affect genes associated with vascular risk factors, as well as with arteriosclerosis and myocardial infarction. Here, we performed a genome-wide association study with 352,228 single-nucleotide polymorphisms typed in 8,842 subjects of the Korea Association Resource (KARE) project and replicated the results in 7,861 subjects from an independent population. We identified genetic associations between platelet count and common variants nearby chromosome 4p16.1 ($p=1.46{\times}10^{10}$, in the KIAA0232 gene), 6p21 ($p=1.36{\times}10^{-7}$, in the BAK1 gene), and 12q24.12 ($p=1.11{\times}10^{-15}$, in the SH2B3 gene). Our results illustrate the value of large-scale discovery and a focus for several novel research avenues.

• 설비공학논문집
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• 제29권7호
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• pp.350-359
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• 2017

Premixed burner is a very strong candidate in household condensing gas boiler burner system because it has low CO and NOx emission with high thermal efficiency. The objective of this study was to determine combustion characteristics of cylindrical premixed burner using different baffle plate and flame holes. Results showed that cylindrical premixed flame mode could be changed into lift-off flame, blue flame, red flame, and green flame with increasing equivalence ratio. In particular, blue flame was found to be very stable at heating load of 8,82~35,280 kcal/h. NOx emission was under 26 ppm between 0.775 to 0.813 of equivalence ratio. CO emission was under 58 ppm under the same equivalence ratio. Thermal efficiency, a very important index in condensing gas boiler, was found to be above 90.13% under the same equivalence region.

• 한국철도학회논문집
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• 제8권6호
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• pp.573-580
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• 2005

Model I interlaminar fracture behaviors of the carbon/epoxy composite, one of the candidate composites for a tilting train carbody, were investigate by the use of DCB(Double cantilever beam) specimens. These specimens were made of CF3327 plain woven fabric with epoxy resin, and an artificial starter delamination was fabricated by inserting Teflon film with the thickness of $12.5{\mu}m$ of $25.0{\mu}m$ at the one end of the specimen. Mode I interlaminar fracture toughness was evaluated for the specimens with the different thickness of an inserter. Also delamination propagating behaviors and interlaminar fracture surface were examined through an ooptical travelling scope and a scanning electron microscope. We found that abruptly unstable crack propagation called as stick-slip phenomena was observed. In addition, interlaminar fracture behaviors were affected on the location and the morphology of a crack tip as well as an interface region.

• 한국재료학회지
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• 제17권5호
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• pp.268-272
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• 2007

Inconel 617 is a candidate tube material for high temperature gas-cooled reactors(HTGR). The microstructure and mechanical properties of Inconel 617 were studied after exposure at high temperature($1050^{\circ}C$). The dominant oxide layer was Cr-oxide. The internal oxide and Cr-depleted region were observed below the Cr-oxide layer. The depth of Cr-depleted zone and internal oxide increased with exposure time. The major phases of carbides are $M_{23}C_6\;and\;M_6C$. The composition of $M_{23}C_6\;and\;M_6C$ were determined to be Cr-rich and Mo-rich, respectively. $M_6C$ carbide is more stable than $M_{23}C_6$ at high temperature. From the results of high temperature compression test, there were no significant changes in hardness and yield strength upon increasing exposure time.

• 한국전자통신학회논문지
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• 제8권11호
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• pp.1647-1654
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• 2013

실외 도로에서의 차량 검출 성능은 기상 상태, 태양 이동에 의한 그림자, 조도 변화 등에 영향을 받는다. 본 논문에서는 낮 시간대의 실외도로에서 이러한 주변 환경변화에 강건한 배경 추정 알고리즘과 연동한 차량 검출 시스템을 제안한다. 배경 추정 알고리즘은 혼합 가우시안 모델을 적용하고 후보 영역에 대한 차량 검출은 Adaboost 알고리즘을 적용하였다. 흐린 날, 비오는 날 등 동일한 실제 도로에서 서로 다른 기후에 획득한 CCTV 비디오 영상을 사용한 실험을 통해 제안하는 방법이 일반 도로에서의 차량 검출에 유용한 것을 확인하였다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 추계학술대회 논문집(제1권)
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• pp.235-240
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• 2006

글로벌 생산네트워크의 변화로 인해 광양항은 새로운 전략의 수립이 요구된다. 특히, 무역의 패턴이 중국, 일본, 한국을 포함한 아시아의 경제적 성장에 따라 동북아지역 집중됨에 따라 가격과 서비스 경쟁력을 가진 광양항은 동북아 포트얼라이언스의 요구에 대처해야하며, 변화하는 무역환경에서 다른 국가들과 경쟁해야 한다. 그러므로 본 연구의 목적은 광양항의 성장을 촉진하기 위한 포트얼라이언스 전략을 제안하는 것이다. 광양항의 물류비즈니스 모델에 대한 목적에 맞도록 동북아 포트얼라이언스의 진행방향과 중국과 일본의 대상 항만을 제공하였다.