• Title/Summary/Keyword: Cancer characteristics

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Is Mammography for Breast Cancer Screening Cost-Effective in Both Western and Asian Countries?: Results of a Systematic Review

  • Yoo, Ki-Bong;Kwon, Jeoung A;Cho, Eun;Kang, Moon Hae;Nam, Jung-Mo;Choi, Kui Son;Kim, Eun Kyung;Choi, Yun Jeong;Park, Eun-Cheol
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.7
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    • pp.4141-4149
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    • 2013
  • Background: Mammography is considered the gold standard of breast cancer mass screening and many countries have implemented this as an established breast cancer screening strategy. However, although the incidence of breast cancer and racial characteristics are different between Western and Asian countries, many Asian countries adopted mammography for mass screening. Therefore, the objective of this research was to determine whether mammography mass screening is cost-effective for both Western and Asian countries. Materials and Methods: A systematic review was performed of 17 national mammography cost-effectiveness data sets. Per capita gross domestic product (GDP), breast cancer incidence rate, and the most optimal cost-effectiveness results [cost per life year saved (LYS)] of a mammography screening strategy for each data set were extracted. The CE/per capita GDP ratio is used to compare the cost-effectiveness of mammography by countries. Non-parametric regression was used to find a cut-off point which indicated the breast cancer incidence rate boundary line determining whether mammography screening is cost-effective or not. Results: We found that the cost-effective cut-off point of breast cancer incidence rate was 45.04; it exactly divided countries into Western and Asian countries (p<0.0014). Conclusions: Mammography screening is cost-effective in most of Western countries, but not in Asian countries. The reason for this result may be the issues of incidence rate or racial characteristics, such as dense breast tissue. The results indicate that mammography screening should be adopted prudently in Asian countries and other countries with low incidence rates.

Factors Influencing Posttraumatic Growth in Patients with Lung Cancer (폐암 환자의 외상 후 성장에 영향을 미치는 요인)

  • Kim, Young Suk;Moon, Jin Ha;Lee, Young Suk;Kim, Yeon Woo;Heo, Gyu Rim;Oh, Soon Keum
    • Journal of Korean Clinical Nursing Research
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    • v.27 no.1
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    • pp.98-108
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    • 2021
  • Purpose: This study was conducted to identify the factors influencing the posttraumatic growth (PTG) in patients with lung cancer and to provide basic data for nursing intervention development to improve PTG and adaptation. Methods: The study included 126 non-small cell lung cancer patients initially diagnosed at the Lung Cancer Center, C University Hospital in S city, Gyeonggi-do. Patients were asked to complete a questionnaire consisting of demographic characteristics, disease characteristics, posttraumatic growth, cancer coping, social support, and resilience. Data were analyzed using t-tests, ANOVA, and Pearson's correlation and multiple regression analysis. Results: The mean score for PTG in lung cancer patients was 56.39, cancer coping was 61.31, social support was 61.09, and resilience was 92.77. Significant positive correlations were found for PTG and cancer coping (r=.75, p<.001), social support (r=.52, p<.001) and resilience (r=.63, p<.001). Factors contributing to PTG of lung cancer patients were cancer coping (β=.53 p<.001), perceived health status(β=.20, p=.002), resilience (β=.21, p=.010) and importance of religion (β=.15, p=.013). This model explained about 64.0% of variances of PTG (F=29.58, p<.001). Conclusion: It is necessary to develop new nursing intervention programs to improve PTG for patients with lung cancer based on strategies to enhance coping and resilience to recovery. Longitudinal studies examining temporal changes in PTG among patients with lung cancer are suggested for future studies in this regard.

Feasibility of Household Surveys for Population Risk Assessment of Cancer and Cancer Registration Support

  • Habib, Omran S;Hussain, Riyadh Abdul-Ameer
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.sup3
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    • pp.213-218
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    • 2016
  • Cancer is a major health problem in the Arab region including Iraq. An adequate database is essential for effective cancer control strategies. Such a database may be provided through cancer registration but supportive household surveys may be useful. This article reports selected results on the feasibility of household surveys to support and validate cancer registration in Basrah governorate - southern Iraq. A large scale multi-stage cluster sample household survey was carried out in Basrah during 2013. It covered 6,999 households and involved gathering data on demographic characteristics and both incident cancer cases and cancer-related deaths among members of these households during a three-year recall period (2010-2012). The data obtained yielded an average annual incidence rate of 91 per 100,000 population (age-standardized incidence rate of 148.8 /100,000) and cancer specific mortality rate of 68 per 100,000 population (age-standardized mortality rate of 126.3/100,000). The results showed an overall pattern of cancer similar to that reported according to cancer registration but the household survey results were consistently higher than those of the cancer registration by a margin of approximately 20- 30% with respect to incident cancer and about 70 % with respect to cancer-specific mortality. Household surveys on cancer, while costly and time consuming, are a very useful additional source of information on cancer at the population level. They can be performed for specific purposes with effective resource mobilization.

Factors Influencing Cancer Rescreening Intention of Korean Elderly (암검진 수검 노인의 재수검의도에 미치는 요인)

  • Kim, Hee-Jung
    • The Korean Journal of Rehabilitation Nursing
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    • v.18 no.2
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    • pp.118-127
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    • 2015
  • Purpose: This study was conducted to survey the cancer screening status of Korean elderly and to analyze factors influencing cancer rescreening intention. Methods: Participants were 262 elderly aged 65 or older who visited medical examination center at D University hospital located in D city. Data were collected from June 1 to July 31, 2012 using a structured questionnaire which included health behavior and cancer screening related characteristics, theory of planned behavior variables, EQ-5D, and cancer screening satisfaction. The data were analyzed by SPSS/WIN 18.0 program. Results: Factors influencing elderly's cancer rescreening intention were 'satisfaction about the cancer screening', 'attitude toward cancer rescreening behavior', 'subjective norm toward cancer rescreening behavior', and 'previous experience with cancer screening in the past 2 years'. Cancer rescreening intention was higher in participants with satisfied experience of cancer screening, more positive in attitude and higher in subjective norm toward cancer rescreening. Cancer rescreening intention was lower when participants were not screened for cancer in the past 2 years. Conclusion: The study results indicate that customized interventions based on influential factors such as subjective norm, attitude toward cancer screening, and cancer screening satisfaction are necessary in order to promote the consistent cancer screening of Korean elderly.

The Approach Method of Community-based Cancer Screening Program in Japan (일본의 지역사회 암 조기 검진사업에 관한 접근 방안)

  • Kim, Yeong-Bok
    • Journal of Korea Association of Health Promotion
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    • v.3 no.2
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    • pp.137-146
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    • 2005
  • The Community based cancer screening program passed in 1960 was a milestone for initiating a national and local health program in Japan. And since then local governments and Cancer Society have been developing and providing cancer screening programs of Stomach, Cervix, Breast and Colorectum for population. To apply the effectiveness of community based cancer screening program, it is important to understand the key issue related to cancer screening participation of population and technology of cancer detection. The purpose of this study was to understand the community based cancer screening program in Japan, and to apply the information for establishment of community based cancer screening program in Korea. The characteristics of community based cancer screening program in Japan were as follows. The first, community based cancer screening program was implemented by the National Health and Medical Services Law for the Aged since 1983. The second, Cancer Society and Cancer Detection Center were core for cancer screening program. The third, the budget for cancer screening program was established by the National Health and Hygiene. The fourth, the continuous quality control for medical staff was provided by Cancer Society and Cancer Detection Center The fifth, the efforts for the promotion of cancer screening rate.

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Weight Changes according to the Period of Chemotherapy Treatments for Breast Cancer (유방암 환자의 화학요법 치료시기에 따른 체중변화)

  • Park, Yun Hee;Yoo, Kyung Hee
    • Journal of Korean Biological Nursing Science
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    • v.18 no.2
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    • pp.94-101
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    • 2016
  • Purpose: This study aimed to evaluate weight changes in women during the period of TAC (docetaxel-doxorubicin-cyclophosphamide) chemotherapy after breast surgery and the differences in weight changes by disease characteristics among Korean women with breast cancer. Methods: The design of this study was retrospective survey research. The subjects of this study were 130 patients with fully completed TAC chemotherapy between January 2012 and April 2015. Body weight before their operation, and at 3 weeks, 6 weeks, 9 weeks, 12 weeks, 15 weeks, and 18 weeks after surgery, as well as general and disease characteristics, were reviewed via their medical charts. Results: The mean age of the patients was 51.2 years. The preoperative (baseline) mean weight was $59.4{\pm}8.44$. Significant weight losses were observed in the initial (1st 3 week) period of TAC chemotherapy compared to the baseline and significant weight losses were observed with the exception of the period 6 weeks after breast surgery. There were significant differences in mean weight changes according to the stage of breast cancer, radiotherapy, and hormone therapy among disease characteristics. Conclusion: It is necessary to study weight changes after breast surgery for the long periods of TAC chemotherapy. Through the accumulated results of studies, nursing programs for breast cancer patients must be developed for the prevention of weight gain in the periods of TAC chemotherapy.

Clinical Characteristics of Advanced Supraglottic Cancer by Subsites (진행된 성문상부암의 발생부위별 임상적 특성에 관한 연구)

  • Jung Kwang-Yoon;Choi Jong-Ouck;Lee Chong-Soo
    • Korean Journal of Head & Neck Oncology
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    • v.9 no.2
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    • pp.193-199
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    • 1993
  • The prognosis of supraglottic cancer is worse than that of glottic cancer. Supraglottic cancers by subsites have different microenvironment of cancer cells, locoregional spread patterns. Therefore we presume that high therapeutic efficacy, while preserving the organ, can be obtained when supraglottic cancer is treated effectively according to its biological behaviors. For the purpose of determination of clinical characteristics and causes of treatment failures by subsites of supraglottis, the authors analyzed 24 cases(stage III 14 cases, stage IV 10 cases) of supraglottic cancer which were managed mainly by surgery in our institute. The results were as follows; 1) The suprahyoid group had worse pathologic grades, more frequent spread to hypopharynx, more freguent recurrence at primary site, and better three-year survival rate than the infrahyoid group. 2) The infrahyoid group had more frequent spread to glottis, understaging, recurrence at cervical nodes than the suprahyoid group. 3) There was no differences in nodal metastasis by sub sites. These results suggest that the suprahyoid group may have more aggressive spread pattern but better prognosis than the infrahyoid group.

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Clinical Analysis of 312 Patients with Hepatobiliary Cancer in Oriental Hospital (한방병원에 내원한 간담도계 암 환자 312례의 임상 분석)

  • Jeong, Tae-Young;Park, Bong-Ky;Cho, Jung-Hyo;Son, Chang-Gue
    • The Journal of Korean Medicine
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    • v.30 no.5
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    • pp.163-173
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    • 2009
  • Objective: This study sought a clinical analysis of hepatobiliary cancer patients treated by oriental medical therapy. Methods: 312 hepatobiliary cancer patients treated in East-west Cancer Center of Dunsan Oriental Hospital from October 2004 to September 2008 were reviewed. These patients' general characteristics and clinical change after treatment were investigated. Results: 83.3% of patients' tumors were stage IV. The median survival period of stage IV patients was 107.0$\pm$82.2 (IVa), 207.0$\pm$26.8 (IVb) days (hepatocellular carcinoma), 132.0$\pm$15.8 days (cholangiocarcinoma), and 203.0$\pm$24.6 days (gallbladder carcinoma). Conclusions: This study presents the general characteristics of hepatobiliary cancer patients treated by Oriental medical therapies, and thus would be valuable for further studies of Oriental medicine-based cancer treatments.

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Prediction Model for Gastric Cancer via Class Balancing Techniques

  • Danish, Jamil ;Sellappan, Palaniappan;Sanjoy Kumar, Debnath;Muhammad, Naseem;Susama, Bagchi ;Asiah, Lokman
    • International Journal of Computer Science & Network Security
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    • v.23 no.1
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    • pp.53-63
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    • 2023
  • Many researchers are trying hard to minimize the incidence of cancers, mainly Gastric Cancer (GC). For GC, the five-year survival rate is generally 5-25%, but for Early Gastric Cancer (EGC), it is almost 90%. Predicting the onset of stomach cancer based on risk factors will allow for an early diagnosis and more effective treatment. Although there are several models for predicting stomach cancer, most of these models are based on unbalanced datasets, which favours the majority class. However, it is imperative to correctly identify cancer patients who are in the minority class. This research aims to apply three class-balancing approaches to the NHS dataset before developing supervised learning strategies: Oversampling (Synthetic Minority Oversampling Technique or SMOTE), Undersampling (SpreadSubsample), and Hybrid System (SMOTE + SpreadSubsample). This study uses Naive Bayes, Bayesian Network, Random Forest, and Decision Tree (C4.5) methods. We measured these classifiers' efficacy using their Receiver Operating Characteristics (ROC) curves, sensitivity, and specificity. The validation data was used to test several ways of balancing the classifiers. The final prediction model was built on the one that did the best overall.

Factors Affecting Breast Cancer Screening Behavior in Japan - Assessment using the Health Belief Model and Conjoint Analysis

  • Tsunematsu, Miwako;Kawasaki, Hiromi;Masuoka, Yuko;Kakehashi, Masayuki
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.6041-6048
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    • 2013
  • Background: Japanese women in their 40s or older have been encouraged to attend breast cancer screening. However, the breast cancer screening rate in Japan is not as high as in Europe and the United States. The aim of this study was to identify psychological and personal characteristics of women concerning their participation in breast cancer screening using the Health Belief Model (HBM). In addition, the attributes of screening more easily accepted by participants were analyzed by conjoint analysis. Materials and Methods: In this cross sectional study of 3,200 age 20-69 women, data were collected by an anonymous questionnaire. Questions were based on HBM and personal characteristics, and included attitudes on hypothetical screening attributes. Data of women aged 40-69 were analyzed by logistic regression and conjoint analysis to clarify the factors affecting their participation in breast cancer screening. Results: Among responses collected from 1,280 women of age 20-69, the replies of 993 women of age 40-69 were used in the analysis. Regarding the psychological characteristics based on HBM, the odds ratios were significantly higher in "importance of cancer screening" (95%CI: 1.21-2.47) and "benefits of cancer screening" (95%CI: 1.09-2.49), whereas the odds ratio was significantly lower in "barriers to participation before cancer screening" (95%CI: 0.27-0.51). Conjoint analysis revealed that the respondents, overall, preferred screening to be low cost and by female staff members. Furthermore, it was also clarified that attributes of screening dominant in decision-making were influenced by the employment status and the type of medical insurance of the women. Conclusions: In order to increase participation in breast cancer screening, it is necessary to disseminate accurate knowledge on cancer screening and to reduce barriers to participation. In addition, the attributes of screening more easily accepted were inexpensive, provided by female staff, executed in a hospital and finished in a short time.