• Journal of Biosystems Engineering
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• 제16권1호
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• pp.9-17
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• 1991

A dynamometer was designed and constructed to measure three directional forces and moments of pull type implement with eliminating the interference between the forces. The dynamometer consists of a linear motion bearing, self-aligning bearings, universal joints, and cantilevers where strain gages were attached. A data acuquisition system was developed to collect data and to analyze them. The data acuquisition system consists of the dynamometer, a potentiometer to measure the implement depth, strain amplifiers, a A/D converter, and an IBM-AT compatible microcomputer. Program, written in C language, was developed to read data from tranducers with given interval, to calculate forces and moments, to display them on screen, and to store them on disk. The calibration results showed that cantilevers had good linearity and there was no interference among directional forces. When applied loads were reduced with constant rate, hysteresis was appeared on the dynamometer. It might to be reduced by using ball bearings instead of self-aligning bearings.

• Journal of the Korean Data and Information Science Society
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• 제15권1호
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• pp.251-261
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• 2004

The paper focuses primarily on the standard linear multiple regression model where the parameter of interest is a ratio of two regression coefficients. The general model includes the calibration model, the Fieller-Creasy problem, slope-ratio assays, parallel-line assays, and bioequivalence. We provide an orthogonal transformation (cf. Cox and Reid (1987)) of the original parameter vector. Also, we give some remarks on the difficulties associated with likelihood based confidence interval.

• 응용통계연구
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• 제10권1호
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• pp.69-84
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• 1997

선형 캘리브레이션 실험계획 문제에 대하여, 베이지안 의사결정론을 이용하여 평균제곱오차손실을 최소화한 Kim(1988, 1993)의 실험계획과 관련 문헌의 결과인 몇 가지 최적계획을 비교한다. 비교대상 실험계획으로서 고전적 추정량의 점근분산을 최소화하는 Buonaccorsi(1986)의 최적계획, 회귀분석 모형에서 $ M(x) = \sum x_i x_i '$의 함수를 최대화 또는 최소화하는 D-optimal 또는 A-optimal 계획, Hunter and Lamboy(1981)가 베이지안 추정량의 특성을 설명하기 위하여 그 논문에서 예로 들었던 실험계획을 고려한다. 서로 다른 기준에 의한 최적계획을 비교하기 위해서 우선 기대사후분산을 계산하여 비교하고 몇가지 사전분포에 대하여 몬테칼로 시뮬레이션을 통한 평균분산과 HPD 구간의 크기를 비교한다.

• 한국해양학회지:바다
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• 제9권4호
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• pp.204-211
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• 2004

자동 수직물성관측 뜰개는 매우 유용한 해양관측장비이지만 이에 부착된 CTD의 사후 보정이 불가능하기 때문에 뜰개자료의 정확도 검증이 사후자료관리나 자료활용에 있어 중요한 문제 중 하나이다. 동해 중심층의 염분변화가 국제 Argo프로그램에서 요구하는 정확도 0.01과 유사하기 때문에 동해를 항염분수조로 취급하여 동해에 투하된 뜰개가 관측한 염분자료의 신뢰성을 세 가지 방법을 통하여 검증하였다. 각각의 방법은 1)부근 해역에서 얻은 정확도가 높은 정선 CTD자료와 뜰개자료의 비교, 2)비슷한 시각에 비슷한 해역에서 얻은 뜰개자료의 비교, 3)체류 수심에서 얻은 염분자료의 장기간에 걸친 안정도 및 정확도 검증이다. 세 방법 모두 뜰개에서 얻은 염분자료가 아무런 보정없이도 Argo프로그램이 요구하는 정확도를 만족함을 보여주었다. 동해의 심층 수온이 일정하다는 가정하에 위의 세 가지 방법을 적용하여 얻은 수온값의 정확도 0.01$^{\circ}C$는 Argo프로그램에서 요구하는 정확도의 2배 정도이다. 하지만 동해의 중층 수온은 Argo프로그램이 요구하는 정확도 이상으로 시공간적으로 변화하기 때문에, 위의 결과는 수온 자료가 부정확하다는 것을 의미하지는 않는다. 동해 중층수온의 시공간적 변화를 고려한다면 수온자료의 정확도도 Argo프로그램이 요구하는 것과 큰 차이가 없다고 할 수 있다. 따라서 이 연구에서 검증된 뜰개가 관측한 수온 염분자료 모두 특별한 보정 없이 사용할 수 있다.

• Journal of Radiation Protection and Research
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• 제12권1호
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• pp.1-11
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• 1987

X-선 target 으로 부터 water phantom($30{\times}30{\times}30cm^3$) 표면까지 1m이고 이 지점에서 비임 크기가 $5cm{\phi},\;10cm{\phi},\;15cm{\phi}$인 경우 phantom 표면으로 부터 X-선 중심축을 따라 깊이 2.5cm의 기준점으로 부터깊이 20cm까지 2.5cm 간격으로 깊이-선량 백분율, P(%)을 추정하였다. 사용된 X-선 인가전압 및 전류는 $150{\sim}250kV$ 및 5 mA 이었고 물속 흡수선량률, $\dot{D}_w$은 NE 2571 공동전리함의 조사선량 교정인자 $N_x$로부터 구한 공기 kerma 고정인자 $N_k$를 이용하여 결정하였다. 기준조사선량룰 $\dot{X}_c$은 Exradin A-2공동 전리함을 일본 ETL로부터 교정하여 X-선 선질을 ETL 교정선질과 같도록 반가층을 결정한 후에 측정되었다. 한편, 흡수선량 및 깊이-선량 백분율 측정의 정확도를 검증하기 위해 phantom 속 깊이 5 cm되는 교정점에서 물속흡수선량률, $\dot{D}_w$을 $N_k$로부터 산출한 값과 Burlin의 일반화된 공동이론을 이용하여 계산한 값을 비교해 보았으며, $N_k$로부터 결정된 깊이-선량 백분율 P(%)을 BJR Suppl. 로부터 구한 값과 비교해 본 결과는 좋은 일치를 보였다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6819-6822
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• 2014

Background: The aim of this study was to evaluate the accuracy of a new scoring system in Korean patients with hematuria at high risk of bladder cancer. Materials and Methods: A total of 319 consecutive patients presenting with painless hematuria without a history of bladder cancer were analyzed, from the period of August 2012 to February 2014. All patients underwent clinical examination, and 22 patients with incomplete data were excluded from the final validation data set. The scoring system included four clinical parameters: age (${\geq}50$ = 2 vs. <50 =1), gender (male = 2 vs. female = 1), history of smoking (smoker/ex-smoker = 4 vs. non-smoker = 2) and nature of the hematuria (gross = 6 vs. microscopic = 2). Results: The area under the receiver-operating characteristic curve (95% confidence interval) of the scoring system was 0.718 (0.655-0.777). The calibration plot demonstrated a slight underestimation of bladder cancer probability, but the model had reasonable calibration. Decision curve analysis revealed that the use of model was associated with net benefit gains over the treat-all strategy. The scoring system performed well across a wide range of threshold probabilities (15%-45%). Conclusions: The scoring system developed is a highly accurate predictive tool for patients with hematuria. Although further improvements are needed, utilization of this system may assist primary care physicians and other healthcare practitioners in determining a patient's risk of bladder cancer.

• 한국도로학회논문집
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• 제17권1호
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• pp.51-58
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• 2015

PURPOSES : The objective of this study is to compare the densities of asphalt pavements measured both in the field and in the laboratory, and also to evaluate the applicability of field density measuring equipment, such as the pavement quality indicator (PQI), by using statistical analysis. METHODS : For the statistical analysis of the density measured from asphalt pavement, student t-tests and a coefficient of correlation are investigated. In order to compare the measured densities, two test sections are prepared, with a base layer and an intermediate layer constructed. Each test section consists of 9 smaller sections. During construction, the field densities are measured for both layers (base and intermediate) in each section. Core samples are extracted from similar regions in each section, and moved to the laboratory for density measurements. All the measured densities from both the field and laboratory observations are analyzed using the selected statistical analysis methods. RESULTS AND CONCLUSION : Based on an analysis of measured densities, analysis using a correlation coefficient is found to be more accurate than analysis using a student t-test. The correlation coefficient (R) between the field density and the core density is found to be very low with a confidence interval less than 0.5. This may be the result of inappropriate calibration of the measuring equipment. Additionally, the correlation coefficient for the base layer is higher than for the intermediate layer. Finally, we observe that prior to using the density measuring equipment in the field, a calibration process should be performed to ensure the reliability of measured field densities.

• Journal of Gastric Cancer
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• 제17권3호
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• pp.204-211
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• 2017

Purpose: Recently, a nomogram predicting overall survival after gastric resection was developed and externally validated in Korea and Japan. However, this gastric cancer nomogram is derived from large-volume centers, and the applicability of the nomogram in smaller centers must be proven. The purpose of this study is to externally validate the gastric cancer nomogram using a dataset from a medium-volume center in Korea. Materials and Methods: We retrospectively analyzed 610 patients who underwent radical gastrectomy for gastric cancer from August 1, 2005 to December 31, 2011. Age, sex, number of metastatic lymph nodes (LNs), number of examined LNs, depth of invasion, and location of the tumor were investigated as variables for validation of the nomogram. Both discrimination and calibration of the nomogram were evaluated. Results: The discrimination was evaluated using Harrell's C-index. The Harrell's C-index was 0.83 and the discrimination of the gastric cancer nomogram was appropriate. Regarding calibration, the 95% confidence interval of predicted survival appeared to be on the ideal reference line except in the poorest survival group. However, we observed a tendency for actual survival to be constantly higher than predicted survival in this cohort. Conclusions: Although the discrimination power was good, actual survival was slightly higher than that predicted by the nomogram. This phenomenon might be explained by elongated life span in the recent patient cohort due to advances in adjuvant chemotherapy and improved nutritional status. Future gastric cancer nomograms should consider elongated life span with the passage of time.

• Journal of Preventive Medicine and Public Health
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• 제39권2호
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• pp.165-170
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• 2006

Objectives : The determination of oxalate in urine is required for the diagnosis and treatment of primary hyperoxaluria, idiopathic stone disease and various intestinal diseases. We examined the possibility of using Fourier transform near-infrared (FT-NIR) spectroscopy analysis to quantitate urinary oxalate. The practical advantages of this method include ease of the sample preparation and operation technique, the absence of sample pre-treatments, rapid determination and noninvasiveness. Methods : The range of oxalate concentration in standard urine solutions was $0-221mg/{\ell}$. These 80 different samples were scanned in the region of 780-1,300 nm with a 0.5 nm data interval by a Spectrum One NTS FT-NIR spectrometer. PCR, PLSR and MLR regression models were used to calculate and evaluate the calibration equation. Results : The PCR and PLSR calibration models were obtained from the spectral data and they are exactly same. The standard error of estimation (SEE) and the % variance were $10.34mg/{\ell}$ and 97.86%, respectively. After full cross validation of this model, the standard error of estimation was $5,287mg/{\ell}$, which was much smaller than that of the pre-validation. Furthermore, the MCC (multiple correlation coefficient) was 0.998, which was compatible with the 0.923 or 0.999 obtained from the previous enzymatic methods. Conclusions : These results showed that FT-NIR spectroscopy can be used for rapid determination of the concentration of oxalate in human urine samples.

• 농업생명과학연구
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• 제53권3호
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• pp.147-157
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• 2019

In this study, we tried to find out the most appropriate pre-processing method and to verify the feasibility of developing a low-price sensing system for predicting the hardy kiwis sugar content based on VNIRS and subsequent spectral analysis. A total of 495 hardy kiwi samples were collected from three farms in Muju, Jeollabukdo, South Korea. The samples were scanned with a spectrophotometer in the range of 730-2300 nm with 1 nm spectral sampling interval. The measured data were arbitrarily separated into calibration and validation data for sugar content prediction. Partial least squares (PLS) regression was performed using various combinations of pre-processing methods. When the latent variable (LV) was 8 with the pre-processing combination of standard normal variate (SNV) and orthogonal signal correction (OSC), the highest R2 values of calibration and validation were 0.78 and 0.84, respectively. The possibility of predicting the sugar content of hardy kiwi was also examined at spectral sampling intervals of 6 and 10 nm in the narrower spectral range from 730 nm to 1200 nm for a low-price optical sensing system. The prediction performance had promising results with R2 values of 0.84 and 0.80 for 6 and 10 nm, respectively. Future studies will aim to develop a low-price optical sensing system with a combination of optical components such as photodiodes, light-emitting diodes (LEDs) and/or lamps, and to locate a more reliable prediction model by including meteorological data, soil data, and different varieties of hardy kiwi plants.