• Title/Summary/Keyword: Calendula officinalis

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Non-enzymatic softening of Calendula officinalis L. petals and its anti-skin aging effect for food materialization (식품소재화를 위한 Calendula officinalis L. 꽃잎의 항피부노화 기능성 규명 및 비효소적 연화 기술 연구)

  • Lim, Seokwon;Choi, Sungbin;Lee, Pomjoo;Kim, Hyung-sup;Lee, Da-young;Byun, Sanguine
    • Korean Journal of Food Science and Technology
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    • v.51 no.3
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    • pp.243-247
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    • 2019
  • Calendula (Calendula officinalis L.) petals are edible flowers which have been used as a decorative ingredient in dishes or as a medicinal food. In this study, the anti-skin aging potential of calendula petals was investigated. Additionally, the texture was softened by non-enzymatic methods to broaden their application as a food or cosmetic agent. Treatment of calendula prevented ultraviolet-induced matrix metalloproteinase-1 expression in skin cells. We investigated whether heating-based processing could soften calendula petals. The results from the punctual test demonstrated significant changes in the hardness of calendula petals depending on the pH, heating temperature, and time. Although there were minor differences among various processing conditions, the largest alteration in hardness was observed when the petals were softened by incubation at $80^{\circ}C$ and pH 2.3 for 120 min. Collectively, these results show that the application of proper processing conditions can soften calendula petals without using enzymes.

Effects of Calendula Officinalis L. Extract on the Activation of Murine Lymphocytes and Macrophages (금잔화 추출물이 생쥐의 임파구 및 대식세포의 활성에 미치는 영향)

  • Eun, Jae-Soon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.4
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    • pp.825-830
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    • 2009
  • The purpose of this research was to investigate the effects of Calendula officinalis extract (CE) on the activation of murine lymphocytes and macrophages. CE was administered p.o. once a day for 7 days at the concentration of 500 mg/kg. The administration of CE increased the viability of thymocytes, but decreased the viability of splenocytes. Also, CE increased the viability of thymocytes and splenocytes at the concentration of $5{\mu}g$/ml in vitro. The administration of CE did not affect the population of thymic $CD4^+$/$CD8^+$ cells and splenic $CD4^+$/$CD8^+$ cells. Furthermore, the administration of CE enhanced the phagocytic activity of peritoneal macrophages, but decreased the phagocytic activity in vitro. CE decreased the production of nitric oxide from peritoneal macrophages in vivo and in vitro system. These results suggest that CE enhance of cell viability by a direct influence on thymocytes and phagocytic activity by an indirect influence on peritoneal macrophages.

Cell Viability and Hair Growth Effect on 3T3-L1 Cells of Ethanol Extract from Calendula officinalis L. Flower, Phellinus linteus Fruit Body and Houttuynia cordata Thunb. Whole Plant (금잔화, 상황, 어성초 에탄올 추출물의 세포독성 평가 및 3T3-L1 세포에 대한 육모 효과)

  • Jin, Seong Woo;Koh, Young Woo;Yun, Kyeong Won;Kim, Kyung Je;Je, Hae Shin;Im, Seung Bin;Kim, Kwang Sang;Kim, Min Sook;Yu, Byung Jo;Seo, Kyoung Sun
    • Korean Journal of Medicinal Crop Science
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    • v.25 no.6
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    • pp.404-410
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    • 2017
  • Background: Hair loss related syndromes are increasing due to environmental pollution and stress. Hair care products are mainly prepared by mixing chemicals and natural extracts, such as those obtained from medicinal plants. The purpose of this study was to investigate the effects of 70% ethanol extracts from the flowers of Calendula officinalis, fruit body of Phellinus linteus, and the whole plant of Houttuynia cordata on the growth of CCD-986 cells, hair follicle dermal papilla cells (HFDPC), and 3T3-L1 cells. Methods and Results: All sample extracts at all concentrations, except for that from P. linteus fruit body at $500{\mu}g/m{\ell}$, were cytotoxic to CCD-986 cells. However, none of the sample extracts were cytotoxic to HFDPC. The lipid differentiation of 3T3-L1 cells regulates hair regeneration via secretion of platelet derived growth factor. The 70% ethanol extract of H. cordata whole plant promoted hair growth. Adipogenesis rate significantly increased in a treatment concentration-dependent manner. Conclusions: These results suggest that 70% ethanol extracts of C. officinalis flower, P. linteus fruit body and H. cordata could be used for the development of hair care products.

The Effects of Marigold(Tagetes L.) Extract and Calendula(Calendula officinalis L.) Extract on Collagen Growth and MMP-1 Expression in Human Dermal Fibroblasts (메리골드(Tagetes L.)와 카렌듈라(Calendula officinalis L.) 추출물이 인간 섬유아세포에서 콜라겐 생성 및 MMP-1 발현에 미치는 영향)

  • Park, Eun-sun;Kim, Su-mi;Moon, Ji-sun
    • Journal of the Korean Applied Science and Technology
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    • v.34 no.4
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    • pp.769-777
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    • 2017
  • To research the effects of marigold extract, which is used mixed with calendula extract, on collagen growth and MMP-1 expression in human fibroblast, we measured cytotoxicity, collagen growth and MMP-1 expression by using HDF cells. The result of measurement showed over 80% cell survival rate in $5{\sim}100{\mu}g/mL$ concentration of marigold extract and calendula extract for HDF cells, which indicates there is no cytotoxicity. The result of measuring collagen synthetic abilities showed both types of extract had collagen synthetic ability increase dose dependently, by 25% in $100{\mu}g/mL$ concentration of marigold extract, and by 7% in $100{\mu}g/mL$ concentration of calendula extract. The result of experimenting the effect on MMP-1 expression showed that both types of extract suppress MMP-1 expression. The result of observing phosphorylation of p-JNK and p-ERK, which are known to be involved with MMP-1 expression, revealed that marigold extract effectively suppresses MMP-1 expression through signaling pathway of p-JNK and p-ERK. The above results confirm the wrinkle improvement effect of marigold extract, and furthermore, it can be used as a cosmetic ingredient for anti-aging.

A Study on the Visible Injury of some Herbaceous Plants by $SO_2$ gas (수종(數種) 초본류(草本類)의 $SO_2$ 가스에 의한 가시피해특징(可視被害特徵)에 관(關)한 연구(硏究))

  • Kim, Jeong-Gyu;Lim, Soo-Kil;Kim, Jae-Bong
    • Korean Journal of Environmental Agriculture
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    • v.7 no.1
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    • pp.43-51
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    • 1988
  • $SO_2$ gas injuries for 19 varieties of 10 species of plants were investigated within a environmentally controlled growth chamber. Visible injuries were observed when exposing the plants either 0, 0.2, 0.4, 0.7 or 1.5ppm of $SO_2$ gas for 5 days from 9 : 00 to 17 : 00 everyday. The results obtained were as follows: 1. Light brown spots were shown on Raphanus sativus(Chunchu, Taeback, Jinjudaepyung), Brassica campestris(Manchun, Josaengmiho, Seoul, Jeonseung), and Capsicum annum(Searona, Hongsanho, Hongilpum); brown spots on Sesamum indicum(Pungnyun, Kwangsan); reddish brown shades on Cleosia cristata; and black brown spots on Perilla frutescens, Calendula officinalis, Chrysanthemum morifolium, and Salvia splendens, respectively. 2. The spotty injuries induced by $SO_2$ gas injuries for 19 varieties of 10 species of plants were investigated within a environmentally controlled growth chamber. Visible injuries were observed when exposing the plants either 0, 0.2, 0.4, 0.7 or 1.5ppm of $SO_2$ gas for 5 days from 9 : 00 to 17 : 00 everyday. The results obtained were as follows: 1. Light brown spots were shown on Raphanus sativus(Chunchu, Taeback, Jinjudaepyung), Brassica campestris(Manchun, Josaengmiho, Seoul, Jeonseung), and Capsicum annum(Searona, Hongsanho, Hongilpum); brown spots on Sesamum indicum(Pungnyun, Kwangsan); reddish brown shades on Cleosia cristata; and black brown spots on Perilla frutescens, Calendula officinalis, Chrysanthemum morifolium, and Salvia splendens, respectively. 2. The spotty injuries induced by SO₂ gas on Raphanus sativus, Callistephus chinensis, Capsicum annum, Perilla frutescens, Calendula officinalis, Salvia splendens, and Sesamum indicum; the many small spots on Chrysanthemum morifolium; and the brown shade on Celosia cristata appeared on the upper surface of the intervein, on the leaf apex area and on the entire upper surface of leaves, respectively. 3. Visual injuries of Capsicum annum(Chunchu), Perilla frutescens, Sesamum indicum(Pungnyun, Kwangsan), and Salvia splendens were developed at 0.4ppm of SO₂ gas fumigation. Brassica campestris(Jeonseung), Capsicum annum(Searona, Hongilpum), and Cleosia cristata, however, showed the injury at 1.5ppm of $SO_2$ gas concentration. 4. Based on the tolerance grade(time when the 1st injury appeared), Raphanus sativus, Perilla frutescens, Sesamum indicum, and Salvia splendens were the most sensitive plants and Chrysanthemum morifolium, Callistephus chinensis, Cleosia cristata, and Calendula officinalis were the plants most tolerant of $SO_2$ gas. gas on Raphanus sativus, Callistephus chinensis, Capsicum annum, Perilla frutescens, Calendula officinalis, Salvia splendens, and Sesamum indicum; the many small spots on Chrysanthemum morifolium; and the brown shade on Celosia cristata appeared on the upper surface of the intervein, on the leaf apex area and on the entire upper surface of leaves, respectively. 3. Visual injuries of Capsicum annum(Chunchu), Perilla frutescens, Sesamum indicum(Pungnyun, Kwangsan), and Salvia splendens were developed at 0.4ppm of $SO_2$ gas injuries for 19 varieties of 10 species of plants were investigated within a environmentally controlled growth chamber. Visible injuries were observed when exposing the plants either 0, 0.2, 0.4, 0.7 or 1.5ppm of $SO_2$ gas for 5 days from 9 : 00 to 17 : 00 everyday. The results obtained were as follows: 1. Light brown spots were shown on Raphanus sativus(Chunchu, Taeback, Jinjudaepyung), Brassica campestris(Manchun, Josaengmiho, Seoul, Jeonseung), and Capsicum annum(Searona, Hongsanho, Hongilpum); brown spots on Sesamum indicum(Pungnyun, Kwangsan); reddish brown shades on Cleosia cristata; and black brown spots on Perilla frutescens, Calendula officinalis, Chrysanthemum morifolium, and Salvia splendens, respectively. 2. The spotty injuries induced by SO₂ gas on Raphanus sativus, Callistephus chinensis, Capsicum annum, Perilla frutescens, Calendula officinalis, Salvia splendens, and Sesamum indicum; the many small spots on Chrysanthemum morifolium; and the brown shade on Celosia cristata appeared on the upper surface of the intervein, on the leaf apex area and on the entire upper surface of leaves, respectively. 3. Visual injuries of Capsicum annum(Chunchu), Perilla frutescens, Sesamum indicum(Pungnyun, Kwangsan), and Salvia splendens were developed at 0.4ppm of SO₂ gas fumigation. Brassica campestris(Jeonseung), Capsicum annum(Searona, Hongilpum), and Cleosia cristata, however, showed the injury at 1.5ppm of $SO_2$ gas concentration. 4. Based on the tolerance grade(time when the 1st injury appeared), Raphanus sativus, Perilla frutescens, Sesamum indicum, and Salvia splendens were the most sensitive plants and Chrysanthemum morifolium, Callistephus chinensis, Cleosia cristata, and Calendula officinalis were the plants most tolerant of $SO_2$ gas. gas fumigation. Brassica campestris(Jeonseung), Capsicum annum(Searona, Hongilpum), and Cleosia cristata, however, showed the injury at 1.5ppm of $SO_2$ gas concentration. 4. Based on the tolerance grade(time when the 1st injury appeared), Raphanus sativus, Perilla frutescens, Sesamum indicum, and Salvia splendens were the most sensitive plants and Chrysanthemum morifolium, Callistephus chinensis, Cleosia cristata, and Calendula officinalis were the plants most tolerant of $SO_2$ gas.

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Antioxidant and Cellular Protective Effects against Oxidative Stress of Calendula officinalis Flowers Extracts in Human Skin Cells (사람피부세포에서 카렌둘라 꽃 추출물의 항산화 및 산화적 스트레스에 대한 세포보호효과)

  • Xuan, Song Hua;Kim, Ga Yoon;Yu, Ji Yeon;Kim, Jee Won;Yang, Ye Rim;Jeon, Young Hee;Jeong, Yoon Ju;Kim, A Rang;Park, Soo Nam
    • Applied Chemistry for Engineering
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    • v.27 no.6
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    • pp.620-626
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    • 2016
  • In this study, we investigated the total phenolic and flavonoid contents, antioxidant activity and cellular protective effects against oxidative stress on human skin cells in 50% ethanol extract and its fractions of Calendula officinalis (C. officinalis) flowers. We measured the antioxidant effects of 50% ethanol extract and its fractions of C. officinalis flowers on the free radical scavenging activity ($FSC_{50}$), the reactive oxygen species (ROS) scavenging activities ($OSC_{50}$) and the inhibition of intracellular ROS generation in human skin cells. These results showed that the antioxidant effect of the ethyl acetate and aglycone fraction was more than the 50% ethanol extract of C. officinalis flowers. We also investigated the cellular protective activity and the results showed that treatment of the ethyl acetate fraction ($0.05-3.13{\mu}g/mL$) protects human skin cells in a concentration-dependent manner when the skin cell damages were induced by treating them with $H_2O_2$. In addition, the aglycone fraction ($1.56-3.13{\mu}g/mL$) shows cellular protective effects on the UV-induced cell damages in a dose-dependent manner. These results suggest that the fractions of C. officinalis flowers can function as a natural antioxidant agent of cosmetics in human skin cells exposed to oxidative stress by ROS scavenging effects.

Seed Pelletizing of Salvia splendens and Calendula officinalis for the Greening and Re-vegetating (녹화와 식생조성을 위한 샐비어와 금잔화 종자의 펠렛처리)

  • Kim, Seung-Hyun;Lee, Byoung-Ryong;Choi, Byoung-Kon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.10 no.5
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    • pp.67-75
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    • 2007
  • The purpose of this study was to pelletize to calendula and salvia seeds with peat moss as basic material for the efficient greening and vegetating of slopes and damaged areas. Also the pelletizing was compressed by spherical types that mixed basic fertilizer of N.;300 mg/l, P.;200 mg/l, K.;400 mg/g and plant growth regulator of A and NAA each 300PPM. Soil and soil surface seeding methods were researched to find the growing state of germination percent, germination date, germination force, length of leaf, number of leaf, width of leaf, length of plant, and etc. Comparing with controlled pelletizing, peat moss and +GA pelletizing treatments resulted in higher from two to three times as following growing states : length of leaves, number of leaves, width of leaves, length of plants, length of roots, fresh weights, and ratio of germination. Especially the two treatments above showed four more times effects than the +NNA treatment. Also their germinating date germinating force were earlier and stronger. The surface seeding method was superior to soil seeding.

Studies on the Phytoextraction of Cadmium and Lead Contaminated Soils by Plants Cultivation (토양중 카드뮴과 납의 Phytoextraction을 위한 식물재배 연구)

  • Jung, Goo-Bok;Kim, Won-Il;Moon, Kwang-Hyun
    • Korean Journal of Environmental Agriculture
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    • v.19 no.3
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    • pp.213-217
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    • 2000
  • In order to select more proper plants for phytoextraction at the heavy metal polluted areas, 11 species of non-edible plants were cultivated at the cadmium(Cd) and Lead(Pb) treated soils and analyzed the content of the absorbed Cd and Pb in each part of plants. Plants include three fibers(Linum usitatissimum, Cannabis sativa, Gossypium spp.), three flowers(Calendula officinalis, Rhododendron lateritium, Portulaca grandiflora), and five trees(Pinus thunbergii, Magnolia kobus, $Populus\;nigra\;{\times}\;P.$ maximowiczii, Euonymus japonica, Fraxinus rhynchophylla). Yield of tree species were higher than that of fiber and flower species. Cd and Pb were highly accumulated in root rather than leaves and stems. The Cd content of plants was in the order Portulaca grandiflora > Calendula officinalis > Gossypium spp. > Linum usitatissimum, Pb was Cannabis sativa > Linum usitatissimum > Fraxinus rhynchophylla. Total absorbed Cd by each plant was in the order $Populus\;nigra\;{\times}\;P.$ maximowiczii > Euonymus japonica > Rhododendron lateritium, but Pb was $Populus\;nigra\;{\times}\;P.$ maximowiczii > Rhododendron lateritium > Euonymus japonica. Total absorbed Cd and Pb contents in plants were negatively correlated with the residual Cd and Pb in the treated soils. It was estimated that $Populus\;nigra\;{\times}\;P.$ maximowiczii, Euonymus japonica, Fraxinus rhynchophylla, and Rhododendron lateritium were the most effective species for phytoextraction in the polluted area considering yield and heavy metal uptake.

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Effect of Storage Film Type on Quality Maintenance in Edible Flower (주요 식용꽃의 포장재 종류에 따른 품질 유지 효과)

  • Lee, Jung A;Yoo, Eun Ha;Kim, Kwang Jin;Kwon, Hye Jin;Song, Jeong Seob
    • FLOWER RESEARCH JOURNAL
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    • v.19 no.4
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    • pp.212-218
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    • 2011
  • Edible flowers are harvested at the full bloom stage and distributed without floral stems, which makes the flower quality deteriorated quickly. Thereby, this study was carried out for selection of effective storage film at room temperature during the distribution of edible flowers. Edible flowers, snapdragon (Antirrhinum majus), pot-marigold (Calendula officinalis), sweet violet (Viola odorata), clove pink (Dianthus caryophyllus), wild pansy (Viola tricolor), nasturtium (Tropaeolum majus) were used to select the effective storage film at room temperature during the distribution, polyethylene (PE) film (0.03 mm), polypropylene (PP) film (0.03 mm). PP (LF10) film packing was very effective for longer shelf life for sweet violet, clove pink, and wild pansy. But, there were little different for pot-marigold and nasturtium. Wilting at sweet violet, clove pink, and wild pansy, and petal-soft rot and color break at nasturtium were appeared. Browning and rot were appeared to snapdragon.

Traditional medicines for common dermatological disorders in Mauritius

  • Mahomoodally, Mohamad Fawzi;Hossain, Ziad Dil
    • CELLMED
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    • v.3 no.4
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    • pp.31.1-31.8
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    • 2013
  • This study has been geared to document primary information on common complementary and alternative medicines (CAM) used to treat and/or manage common dermatological disorders in Mauritius, a tropical multicultural island in the Indian Ocean. Data from 355 key informants was collected via a semi-structured questionnaire. Pearson correlation and Chi-squared test were performed to delineate any association. Quantitative indexes including the Importance Value (IV) and fidelity value were calculated. Results tend to indicate that cultural reasons were behind the use of CAM among Mauritians and traditional knowledge was mainly acquired either from parents/relatives or from self-experience. Among the medicinal plants mentioned, Aziadiracta indica (IV = 0.78) and Paederia tomentosa (IV = 0.70) were found to be most used plants. Calendula officinalis (IV = 0.15), Centella asiatica (IV = 0.22) and Agauria salicifolia (IV = 0.11) were also recorded to be used for common dermatological disorders though greatly under-utilised. Animal products were mentioned by 38.0% respondents and cow ghee was found to be commonly used in the management of measles (IV = 0.88). Spiritual healing was found to be used mainly for measles and warts. Given the plethora of novel information documented from the present survey, it can be suggested that the Mauritian population still relies to a great extent on CAM which needs to be preserved and used sustainably. Nonetheless, further investigation is required to probe the possible active constituents that could be the basis of an evidence based investigation to discover new drugs.