• 제목/요약/키워드: Cadaveric data

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가상 생체외 사체 실험용 경추 다물체 동역학 모델 개발 (Development of Multibody Dynamic Model of Cervical Spine for Virtual In Vitro Cadaveric Experiment)

  • 임대섭;이기석;김윤혁
    • 대한기계학회논문집B
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    • 제37권10호
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    • pp.953-959
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    • 2013
  • 본 연구에서는 가상 생체외 사체실험을 수행할 수 있는 경추 다관절 동역학 모델을 개발하였다. 평균크기 한국인 의료영상과 관절 및 연부조직의 물성 정보를 기반으로 하여 경추 동역학 모델을 개발하였다. 개발된 모델의 검증을 위하여 경추 단분절 및 다분절 모멘트-각도 관계, 인대 하중 및 후관절 접촉력 등을 문헌의 사체실험 결과와 비교한 결과 매우 유사한 경향을 확인하였다. 본 연구에서 개발된 경추 동역학 모델은 앞으로 경추 사체실험 연구 뿐만 아니라 자동차 충돌시 경추 상해 분석 등의 다양한 경추 생체역학 연구 연구에 활용될 수 있을 것이다.

The Changes in Range of Motion after a Lumbar Spinal Arthroplasty with Charite$^{TM}$ in the Human Cadaveric Spine under Physiologic Compressive Follower Preload: A Comparative Study between Load Control Protocol and Hybrid Protocol

  • Kim, Se-Hoon;Chang, Ung-Kyu;Chang, Jae-Chil;Chun, Kwon-Soo;Lim, T. Jesse;Kim, Daniel H.
    • Journal of Korean Neurosurgical Society
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    • 제46권2호
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    • pp.144-151
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    • 2009
  • Objective: To compare two testing protocols for evaluating range of motion (ROM) changes in the preloaded cadaveric spines implanted with a mobile core type Charite$^{TM}$ lumbar artificial disc. Methods: Using five human cadaveric lumbosacral spines (L2-S2), baseline ROMs were measured with a bending moment of 8 Nm for all motion modes (flexion/extension, lateral bending, and axial rotation) in intact spine. The ROM was tracked using a video-based motion-capturing system. After the Charite$^{TM}$ disc was implanted at the L4-L5 level, the measurement was repeated using two different methods: 1) loading up to 8 Nm with the compressive follower preload as in testing the intact spine (Load control protocol), 2) loading in displacement control until the total ROM of L2-S2 matches that when the intact spine was loaded under load control (Hybrid protocol). The comparison between the data of each protocol was performed. Results: The ROMs of the L4-L5 arthroplasty level were increased in all test modalities (p < 0.05 in bending and rotation) under both load and hybrid protocols. At the adjacent segments, the ROMs were increased in all modes except flexion under load control protocol. Under hybrid protocol, the adjacent segments demonstrated decreased ROMs in all modalities except extension at the inferior segment. Statistical significance between load and hybrid protocols was observed during bending and rotation at the operative and adjacent levels (p< 0.05). Conclusion: In hybrid protocol, the Charite$^{TM}$ disc provided a relatively better restoration of ROM, than in the load control protocol, reproducing clinical observations in terms of motion following surgery.

사체간이식 환자와 생체간이식 환자들의 삶의 질 비교 연구 (Comparing Quality of Life following Liver Transplantation for Cadaveric versus Living Donor Liver Transplant Recipients: A Single-Center Study)

  • 김금희;윤석준;안형식;이준영;박형근;서경석
    • 한국의료질향상학회지
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    • 제11권1호
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    • pp.32-45
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    • 2004
  • Objective : The aim of this study were to measure quality of life(QOL) in liver transplant recipients, to compare QOL between living donor liver transplant recipients and cadaveric liver transplant recipients and to investigate whether SF-36 may be used as a disease-specific instrument in liver transplant recipients. Methods : We conducted a single-center cross-sectional study of 133 LT recipients ages 13 to 65 years, all of whom had had Liver Transplantation(LT) at least 1 months previously. QOL was assessed using a self-completion questionnaire consisting of the Bang Whal Ran(1991) instruments and the 36-Item Short-Form Health Survey(SF-36) health status profile measure. We investigated whether the SF-36 instrument may be used as a disease-specific instrument in LT recipients. Individual scale scores range from 0 to 100, with higher score reflecting better health. Data on demographics, clinical status at pre transplantation 1 day, post transplantation clinical status, and graft function were collected to identify predictors of post transplantation QOL. Results : Standard measures for test-retest reliability, internal consistency, and discriminant and concurrent validity were examined. The reliability of the SF-36, as measured by test-retest correlation(Pearson coefficients: 0.729, p=0.002) and by internal consistency(Cronbach's alpha: 0.9431) exceeded conventional acceptability criteria. The correlation between domain scores of SF-36 and the Bang Whal Ran(l991) was clear and logical in that the clinical characteristics of SF-36 strongly correlated with the clinical component summary score of the Bang Whal Ran(l991)(r = 0.8155, P<.01). SF-36 scale scores were compared between Cadaveric Liver Transplant recipients and Living Donor Liver Transplant recipients. Donor types of post LT did not influence HRQOL(p>0.05). 87% of the liver transplant recipients were satisfied to get LT. Satisfaction of post LT showed significantly greater HRQOL(p<0.001). Conclusion : SF-36 is found reliable and valid. This study indicates thet Donor Type did not influence HRQOL after LT. The information gained from this study will help us to better define expectations and the clinical course after liver transplantation to patients and their families.

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Donor Surgical Morbidity in Pediatric Living-Donor Liver Transplant: A Portuguese Experience

  • dos Santos, Jose Pedro Fernandes;Martins, Ricardo;Lopes, Maria Francelina
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제24권6호
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    • pp.528-534
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    • 2021
  • Purpose: Living-donor liver transplant emerged as an alternative treatment for end stage liver disease due to the lack of cadaveric organs availability that met the demand. In Portugal, pediatric living-donor liver transplant (P-LDLT) was initiated in 2001 in Portugal in order to compensate for the scarcity of cadaveric organs for such cases. The aim of this study was to retrospectively analyze the morbi-mortality of the 28 donors included in P-LDLT program performed at Coimbra's Pediatric Hospital (CHUC), a Portuguese reference center. Methods: We retrospectively collected pertinent donor data and stratified complications according to Clavien's scoring system. Results: In total, 28.6% (n=8) of the donors had surgical complications. According to Clavien-Dindo's classification, two donors had major complications (Clavien grade ≥3), four donors had grade 2 complications, and two donors had grade 1 complications. There were no P-LDLT-related mortalities in the present case series. The most common verified complications were biliary tract injuries and superficial incisional infections, which are consistent with the complications reported in worldwide series. Conclusion: These patients from CHUC shows that donor hepatectomy in P-LDLT is a safe procedure, with low morbidity and without mortality.

카데바 자료를 이용한 얼굴근육의 해부학적 기능 학습을 위한 삼차원 교육 콘텐츠 제작과 관련된 융합 연구 (Convergence Study on the Three-dimensional Educational Model of the Functional Anatomy of Facial Muscles Based on Cadaveric Data)

  • 이재기
    • 한국융합학회논문지
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    • 제12권9호
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    • pp.57-63
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    • 2021
  • 이 연구는 한국인 성인 시신의 얼굴근육을 해부하고 삼차원 스캔하여, 사실적인 얼굴근육의 형태를 삼차원 오브젝트를 만들고, 이를 통해 표정을 재현하여 카데바 얼굴근육의 복합적인 움직임을 삼차원적으로 관찰 가능한 교육 자료를 제작하는데 목적이 있다. 카데바 해부 사진 자료를 이용하여, 얼굴근육에 대해 삼차원 모델링 하였고, 네 가지 표정(슬픔, 미소, 놀람, 분노)에 따라 얼굴근육이 변화하는 삼차원 영상을 제작하였다. 이를 통해, 삼차원으로 구현한 카데바 얼굴근육의 복합적인 작용과 다양한 표정 변화를 확인할 수 있었다. 이 연구결과는 얼굴근육의 개별적인 기능에 대한 정량적인 자료를 확인할 수는 없지만, 사실적이고 입체적인 카데바의 얼굴근육 형태를 관찰할 수 있고, 복합적인 얼굴근육의 작용으로 인한 표정 변화를 확인할 수 있다. 이러한 자료는 얼굴근육의 해부학적 교육 자료로 활용할 수 있을 것으로 기대한다.

Morphometric Study of the Nerve Roots Around the Lateral Mass for Posterior Foraminotomy

  • Hwang, Jae-Chan;Bae, Hak-Geun;Cho, Sung-Won;Cho, Sung-Jin;Park, Hyung-Ki;Chang, Jae-Chil
    • Journal of Korean Neurosurgical Society
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    • 제47권5호
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    • pp.358-364
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    • 2010
  • Objective : Morphometric data on dorsal cervical anatomy were examined in an effort to protect the nerve root near the lateral mass during posterior foraminotomy. Methods : Using 25 adult formalin-fixed cadaveric cervical spines, measurements were taken at the lateral mass from C3 to C7 via a total laminectomy and a medial one-half facetectomy. The morphometric relationship between the nerve roots and structures of the lateral mass was investigated. Results from both genders were compared. Results : Following the total laminectomy, from C3 to C7, the mean of the vertical distance from the medial point of the facet (MPF) of the lateral mass to the axilla of the root origin was 3.2-4.7 mm. The whole length of the exposed root had a mean of 4.2-5.8 mm. Following a medial onehalf facetectomy, from C3 to C7, the mean of the vertical distance to the axilla of the root origin was 2.1-3.4 mm, based on the MPF. Mean vertical distances from the MPF to the medial point of the root that crossed the inferior margin of the intervertebral disc were 1.2-2.7 mm. The mean distance of the exposed root was 8.2-9.0 mm, and the mean angle between the dura and the nerve root was significantly different between males and females, at $53.4-68.4^{\circ}$. Conclusion : These data will aid in reducing root injuries during posterior cervical foraminotomy.

한국의 장기이식과 관련된 윤리적 고려사항의 분석 (A study of the current ethical situation in organ transplantations in Korea)

  • 한성숙;황경식;맹광호;이동익;엄영란
    • 대한간호학회지
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    • 제28권1호
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    • pp.26-36
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    • 1998
  • This primary study was done to develop an ethical guideline for organ transplantation, a life-saving treatment which helps improve the quality of life. This study tried to identify the current situation in Korea, in terms of ethical considerations in organ transplantations. This study collected basic data in organ transplantations, in the hope that procedure of organ transplantations could be developed that would be fair to both organ donors and recipients. The immediate goals of this study were : 1)to identify staff in charge of organ transplantations and their jobs in the hospital, 2)to survey whether there exists a Hospital Ethics Committee(HEC), 3)to research what consideration are formally taken in selecting recipients, and 4)to accumulate data on how consent from donors are currently obtained. The study used a survey questionnaire and received responses from 31 hospitals out of 45 hospitals where organ transplantation are being done. Organ transplantation coordinators were found in 16 hospitals, but the job description varied among hospitals. The survey showed that all 16 hospitals with an HEC that health care personnel unnecessarily dominate the committee. The study notes that HECs should be vitalized by recruiting, as members, ethicists, theologians, patients, guardians, as well as the general public outside of the hospital. The study revealed that in selecting recipients the hospital take into account ABO blood type, histocompatibility, age, waiting time. and level of patient compliance. Finally, it was shown that in the cases of living donors the transplanting hospitals seek a formal consent, whereas there are no common consenting practice established for cadaveric donors. The study concludes with three proposals. First, a nationwide institution responsible exclusively for procurement and distribution of cadaveric organs for transplantation should be established. Second. we should rebuild the national health insurance system so that have costly organ transplantation expenses are substantially covered. Last, but certainly not least. there is a need to emphasize the HEC's committment to prepare a proper ethical guideline for organ transplantation in general.

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의사소통 기술과 해부학 실습 설명의 융합 : 의과대학 학생들의 자기평가 요소와 학문적 성취감의 상관관계 (Convergence of Explanation Meeting in Cadaveric Dissection with Communication Skill : Correlation between Self-evaluation Factor and Academic Achievement of Medical Students)

  • 박정현;임희경;김지희
    • 디지털융복합연구
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    • 제14권8호
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    • pp.363-370
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    • 2016
  • 본 연구의 목적은 해부학실습에서 의과대학 학생들의 설명을 도입하여 만족도, 전공과의 연계성, 운영의 적절성, 언어적, 비언어적 의사소통을 포함한 자기평가요인과 학업성취도의 상관관계를 알아보고자 하였다. 의과대학 학생들은 보건관련학과 학생들에게 해부학 실습을 통해 시신의 구조를 설명과 토의를 하였다. 그 직후, 102명의 의과대학 학생들은 자기 평가요인과 의사소통의 영향에 관한 자기기입식 설문을 작성하였다. 연구기간은 2012년 6월부터 9월까지였다. 자료는 빈도 분석, t-test, 변량분석으로 처리되었다. 성별, 나이, 해부학 설명회의 경험에 관계없이 학생들은 자기평가요인의 모든 질문에서 높은 점수를 기록하였다. 그 중에서, 전공과의 연계성, 언어적 의사소통 요인은 학업성취도와 밀접한 관계가 있었다 (p<0.05). 언어적, 비언어적 의사소통 요인 또한 0.580의 높은 상관관계를 보였다. (p<0.01). 해부학 설명 과정은 의과대학 학생들에게 긍정적인 태도로 더 배우려는 기회를 제공하였고, 학업 동기를 부여하였다.