• Bulletin of the Korean Chemical Society
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• v.31 no.5
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• pp.1159-1164
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• 2010

Several triterpenoid saponins from root of Pulsatilla koreana Nakai (Ranunculaceae) were studied and their biological activities were reported. It is difficult to analyze triterpenoid saponins using HPLC-UV due to the lack of chromophores. So, evaporative light scattering detection (ELSD) is used as a valuable alternative to UV detection. More recently, a charged aerosol detection (CAD) has been developed to improve the sensitivity and reproducibility of ELSD. In this study, we developed and validated a novel method of high performance liquid chromatography coupled with a charged aerosol detector for the simultaneous determination of four triterpenoid saponins: pulsatilloside E, pulsatilla saponin H, anemoside B4 and cussosaponin C. Analytes were separated by the Supelco Ascentis$^{(R)}$ Express C18 column (4.6 mm ${\times}$ 150 mm, 2.7 ${\mu}m$) with gradient elution of methanol and water at a flow rate of 0.8 mL/min at $30^{\circ}C$. We examined various factors that could affect the sensitivity of the detectors, including various concentrations of additives, the pH of the mobile phase, and the CAD range. Linear calibration curves were obtained within the concentration ranges of 2 - 200 ${\mu}g$/mL for pulsatilloside E, anemoside $B_4$ and cussosaponin C, and 5 - 500 ${\mu}g$/mL for pulsatilla saponin H with correlation coefficient ($R^2$) greater than 0.995. The limit of detection (LOD) and quantification (LOQ) were 0.04 - 0.2 and 2 - 5 ${\mu}g$/mL, respectively. The validity of the developed HPLC-CAD method was confirmed by satisfactory values of linearity, intra- and inter-day accuracy and precision. This method could be successfully applied to quality evaluation, quality control and monitoring of Pulsatilla koreana.

• The Journal of Advanced Prosthodontics
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• v.8 no.6
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• pp.417-422
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• 2016

PURPOSE. The purposes of this study were to evaluate the staining resistance of CAD/CAM resin-ceramics polished with different techniques and to determine the effectiveness of the polishing techniques on resin-ceramics, comparing it with that of a glazed glass-ceramic. MATERIALS AND METHODS. Four different CAD/CAM ceramics (feldspathic ceramic: C-CEREC Blocs, (SIRONA) and three resin-ceramics: L-Lava Ultimate, (3M ESPE), E-Enamic, (VITA) and CS-CeraSmart, (GC)) and one light cure composite resin: ME-Clearfil Majesty Esthetic (Kuraray) were used. Only C samples were glazed (gl). Other restorations were divided into four groups according to the polishing technique: nonpolished control group (c), a group polished with light cure liquid polish (Biscover LV BISCO) (bb), a group polished with ceramic polishing kit (Diapol, EVE) (cd), and a group polished with composite polishing kit (Clearfil Twist Dia, Kuraray) (kc). Glazed C samples and the polished samples were further divided into four subgroups and immersed into different solutions: distilled water, tea, coffee, and fermented black carrot juice. Eight samples ($8{\times}8{\times}1mm$) were prepared for each subgroup. According to CIELab system, four color measurements were made: before immersion, immersion after 1 day, after 1 week, and after 1 month. Data were analyzed with repeated measures of ANOVA (${\alpha}=.05$). RESULTS. The highest staining resistance was found in gl samples. There was no difference among gl, kc and cd (P>.05). Staining resistance of gl was significantly higher than that of bb (P<.05). Staining resistances of E and CS were significantly higher than those of L and ME (P<.05). CONCLUSION. Ceramic and composite polishing kits can be used for resin ceramics as a counterpart of glazing procedure used for full ceramic materials. Liquid polish has limited indications for resin ceramics.

• IE interfaces
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• v.12 no.3
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• pp.480-486
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• 1999

Mold base design is one of the most critical steps in production of plastic parts. This paper presents an efficient method for generating a 3D CAD library for injection mold base and mold components. In this paper, a new description language (DL)formats are proposed. These DL formats can represent the geometric feature, the variable dimensions and the assembly structures of mold base and its components. And the processes of adding the mold components and creating the mold assemblies can be performed very easily and efficiently by using DL scripts. Proposed method has been tested by implementation of 3D library with DL scripts and DL-interpreter with C language. The DL and interpreter are independent of CAD system. They were applied to the automatic mold base designing system which works on Unigraphics V15. The system is developed with UG API function under Windows-NT environment.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1994.04a
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• pp.703-712
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• 1994

This paper presents an automatic conversion of machining data from the orthographic views of press mold by feature recognition rule. The system includes following 6 modules : separation of views, function support, dimension text recognition, feature recognition, dimension text check and feature processing modules. The characteristic of this system is that with minimum user intervention, it recognizes basic features such as holes, slots, pockets and clamping parts and thus automatically converts CAD drawing details of press mold into machining data using 2D CAD system instead of using an expensive 3D Modeler. The system is developed by using IBM-PC in the environment of AutoCAD R12, AutoLISP and MetaWare High C. Performance of the system is verified as a good interfacing of CAD and CAM when applied to a lot of sample drawings.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.04a
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• pp.660-664
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• 1997

본 논문은 사출금형 설계를 위한 전문가 시스템의 개발에 관한 연구이다. 설계자가 오토케드 (AutoCAD)환경에서 금형부품 및 몰드베이스를 3차원 형상으로 나타낼 수 있으며 필요한 설계 데이터를 추가할수 있는 프로그램 개발에 있다. 주 프로그램은 C++를 사용하여 구축하였으며,금형부품 치수 및 몰 드베이스를 데이터베이스화 하였다. 주 프로그램과 오토캐드와 인터페이스를 하여 오토캐드 환경에서 자 유롭게 사용할 수 있도록 하였다. Pull-down menu와 Dialog box를 이용하여 금형 설계자가 금형의 각 부 품을 자유롭게 선정할 수 있으며, 각 단계별 선정된 금형부품은 즉시 나타나 설계자가 바로 확인 할 수 있도록 하였다. 이젝터 핀의 위치 및 크기를 자동적으로 나타낼수 있으며, 선정된 금형 부품 및 몰드베이 스는 2차원이나 3차원으로 나타낼 수 있다. 각각의 3차원 부품을 독립적으로 나타낼 수 있어 NC프로그램과 인터페이스가 가능토록 하였다.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.04a
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• pp.703-707
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• 1997

DUe to the requirement of high precision and the complexity during the tool design for electron gun elements, it sometimes causes human-errors. Also, in the case of beginners, they have more trial and error than skilled engineers. To remove these problems and increase the productivity in the practice field, it need the deveiopment of CAD system for electron gun element tools. Through this study, a CAD system of electron gun element tools which is used by used by knowledge base system including expert's technology in the practics, has been developed. To developed this system, it has used C-language under HP-UNIX system and CIS customer language of the EXCESS CAD/CAM system. An application of this system will provide effective aids to the designer in this field.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1996.04a
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• pp.592-596
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• 1996

The CAD/CAM System oriented to StereoLithographic Rapid Prototyping was constructed and developed. The software architecture uses a 586PC running the windows NT operating system. An .STL file brought into the software program can be verified in divers view points and focused for a detail of concern. A variety of Entity was applied to define an array of triangular facets and sliced loops. The system provides Edit, Scale, Orient, Copy and Divide commands to modify .STL model. The NC codes are created according to various laser beam scan pattern and the software show the parts on the platform before they are constructed. This system is written in Visual C and has been proved as a powerful tool for producing solid parts directly from a CAD modelling, using actual applications.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1992.10a
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• pp.112-120
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• 1992

The use of Pre-processor for building structural analysis used to rely upon filling up fixed format data, which was ineffective and error-prone. This research attempts to integrate structural analysis system with DBMS and CAD system in order to make it easy to exchange data between pre-process, analysis, and post-process stages. Automatic generation of database from pre-process stage allows easy preparation of main input data for other structural analysis programs. CAD system with some sub-programs written in LISP and C works as a graphic user interface. This approach gives an easy, effective and error-free way of inputing data for structural analysis.

• IE interfaces
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• v.7 no.3
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• pp.181-191
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• 1994

This paper presents an automatic conversion of machining data from the orthographic views of press mold by feature recognition rule. The system includes following 6 modules : separation of views, function support, dimension text check and feature processing modules. The characteristic of this system is that with minimum user intervention, it recognizes basic features such as holes, slots, pockets and clamping parts and thus automatically converts CAD drawing details of press mold into machining data using 2D CAD system instead of using an expensive 3D Modeler. The system is developed by using IBM-PC in the environment of AutoCAD R12, AutoLISP and MetaWare High C. Performance of the system is verified as a good interfacing of CAD and CAM when applied to a lot of sample drawing.

• The Journal of Korean Academy of Prosthodontics
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• v.47 no.1
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• pp.53-60
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• 2009

Statement of problem: At present, as the esthetic demands are on the increase, there are many ongoing studies for tooth-colored post and cores. Most of them are about fiber post and prefabricated zirconia post, but few about one-piece milled zirconia post and core using CAD/CAM (computer-aided design/computer-aided manufacturing) technique. Purpose: The objective of this study was to compare microleakage of endodontically treated teeth restored with three different tooth-colored post and cores. Material and methods: Extracted 27 human maxillary incisors were cut at the cementoenamel junction, and the teeth were endodontically treated. Teeth were divided into 3 groups (n=9); restored with fiber post and resin core, prefabricated zirconia post and heat-pressed ceramic core, and CAD/CAM milled zirconia post and core. After the preparation of post space, each post was cemented with dual-polymerized resin cement (Variolink II). Teeth were thermocycled for 1000 cycles between $5-55^{\circ}C$ and dyed in 2% methylene blue at $37^{\circ}C$ for 24 hours. Teeth were sectioned (bucco-lingual), kept the record of microleakage and then image-analyzed using a microscope and computer program. The data were analyzed by one-way ANOVA and Scheffe's multiple range test (${\alpha}=0.05$). Results: All groups showed microleakage and there were no significant differences among the groups (P>.05). Prefabricated zirconia post and heat-pressed ceramic core showed more leakage in dye penetration at the post-tooth margin, but there was little microleakage at the end of the post. Fiber post and resin core group and CAD/CAM milled zirconia post and core group indicated similar microleakage score in each stage. Conclusion: Prefabricated zirconia post and heat-pressed ceramic core group demonstrated better resistance to leakage, and fiber post and resin core group and CAD/CAM milled zirconia post and core group showed the similar patterns. The ANOVA test didn't indicate significant differences in microleakage among test groups. (P>.05)