• The Journal of Advanced Prosthodontics
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• 제13권5호
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• pp.304-315
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• 2021

PURPOSE. Esthetic expectations have increased the use of polyetheretherketone (PEEK) clasps as alternatives to Cr-Co in removable partial dentures (RPDs). The objective of this study was to evaluate the retentive force and dimensional change of clasps with different thickness and undercut made from PEEK by the thermo-mechanical fatigue. MATERIALS AND METHODS. PEEK clasps (N = 48) with thicknesses of 1 or 1.50 mm and 48 premolar monolithic zirconia crowns with undercuts of 0.25 mm or 0.50 mm were fabricated. Samples are divided into four groups (C1-C4) and were subjected to 7200 thermal aging cycles (at 5 - 55℃). The changes in the retentive force and dimensions of the clasps were measured by micro-stress testing and micro-CT devices from five measurement points (M1 - M5). One-way ANOVA, paired t-test, two-way repeated ANOVA, and post-hoc tests were used to analyze the data (P < .05). RESULTS. The retentive forces of C1, C2, C3, and C4 groups in initial and final test were found to be 4.389-3.388 N, 4.67 - 3.396 N, 5.161 - 4.096 N, 5.459 - 4.141 N, respectively. The effects of retentive force of all PEEK clasps groups were significant decreased. Thermo-mechanical cycles caused significant dimensional changes at points with M2, M4, and M5, and abraded the clasp corners and increased the distance between the ends of the clasp, resulting in reduced retentive forces (P^* = .016, P^* = .042, P < .001, respectively). CONCLUSION. Thermo-mechanical aging decreases the retentive forces in PEEK clasps. Increasing the thickness and undercut amount of clasps decreases the amount of dimensional change. The values measured after aging are within the clinically acceptable limits.

• Korean Journal of Radiology
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• 제19권6호
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• pp.1021-1030
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• 2018

Objective: We evaluated the effect of various patient characteristics and time-density curve (TDC)-factors on the test bolus-affected vessel enhancement on coronary computed tomography angiography (CCTA). We also assessed the value of generalized linear regression models (GLMs) for predicting enhancement on CCTA. Materials and Methods: We performed univariate and multivariate regression analysis to evaluate the effect of patient characteristics and to compare contrast enhancement per gram of iodine on test bolus (${\Delta}HUTEST$) and CCTA (${\Delta}HUCCTA$). We developed GLMs to predict ${\Delta}HUCCTA$. GLMs including independent variables were validated with 6-fold cross-validation using the correlation coefficient and Bland-Altman analysis. Results: In multivariate analysis, only total body weight (TBW) and ${\Delta}HUTEST$ maintained their independent predictive value (p < 0.001). In validation analysis, the highest correlation coefficient between ${\Delta}HUCCTA$ and the prediction values was seen in the GLM (r = 0.75), followed by TDC (r = 0.69) and TBW (r = 0.62). The lowest Bland-Altman limit of agreement was observed with GLM-3 (mean difference, $-0.0{\pm}5.1$ Hounsfield units/grams of iodine [HU/gI]; 95% confidence interval [CI], -10.1, 10.1), followed by ${\Delta}HUCCTA$ ($-0.0{\pm}5.9HU/gI$; 95% CI, -11.9, 11.9) and TBW ($1.1{\pm}6.2HU/gI$; 95% CI, -11.2, 13.4). Conclusion: We demonstrated that the patient's TBW and ${\Delta}HUTEST$ significantly affected contrast enhancement on CCTA images and that the combined use of clinical information and test bolus results is useful for predicting aortic enhancement.

• The Journal of Advanced Prosthodontics
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• 제14권2호
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• pp.70-77
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• 2022

PURPOSE. This study evaluated screw loosening and 3D crown displacement after cyclic loading of implant-supported incisor crowns cemented with original titanium bases or with three compatible, nonoriginal components. MATERIALS AND METHODS. A total of 32 dental implants were divided into four groups (n = 8 each): Group 1 used original titanium bases, while Groups 2-4 used compatible components. The reverse torque value (RTV) was evaluated prior to and after cyclic loading (1,200,000 cycles). Samples (prior to and after cyclic loading) were scanned with a microcomputed tomography (micro-CT). Preload and postload files were superimposed by 3D inspection software, and 3D crown displacement analysis was performed using root-mean-square (RMS) values. All datasets were analyzed using one-way ANOVA and Tukey's post hoc analysis. RESULTS. Significant variations were observed in the postload RTV, depending on the titanium base brand (P < .001). The mean postload RTVs were significantly higher in Groups 1 and 2 than in the other study groups. While evaluating 3D crown displacement, the lowest mean RMS value was shown in the original Group 1, with the highest RMS value occurring in Group 4. CONCLUSION. Within the limitations of this in vitro study and under the implemented conditions, it was concluded that the manufacturer brand of the titanium base significantly influenced screw loosening following the fatigue test and influenced 3D crown displacement after cyclic loading.

• 한국동물생명공학회지
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• 제37권2호
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• pp.96-105
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• 2022

The ovary undergoes substantial physiological changes along with estrus phase to mediate negative/positive feedback to the upstream reproductive tissues and to play a role in producing a fertilizable oocyte in the developing follicles. However, the disorder of estrus cycle in female can lead to diseases, such as cystic ovary which is directly associated with decline of overall reproductive performance. In gene expression studies of ovaries, quantitative reverse transcription polymerase chain reaction (qPCR) assay has been widely applied. During this assay, although normalization of target genes against reference genes (RGs) has been indispensably conducted, the expression of RGs is also variable in each experimental condition which can result in false conclusion. Because the understanding for stable RG in porcine ovaries was still limited, we attempted to assess the stability of RGs from the pool of ten commonly used RGs (18S, B2M, PPIA, RPL4, SDHA, ACTB, GAPDH, HPRT1, YWHAZ, and TBP) in the porcine ovaries under different estrus phase (follicular and luteal phase) and cystic condition, using stable RG-finding programs (geNorm, Normfinder, and BestKeeper). The significant (p < 0.01) differences in Ct values of RGs in the porcine ovaries under different conditions were identified. In assessing the stability of RGs, three programs comprehensively agreed that TBP and YWHAZ were suitable RGs to study porcine ovaries under different conditions but ACTB and GAPDH were inappropriate RGs in this experimental condition. We hope that these results contribute to plan the experiment design in the field of reproductive physiology in pigs as reference data.

• 보존과학회지
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• 제38권4호
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• pp.277-288
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• 2022

'Eve 58-1', the subject of this study is a statue made of plaster and its structural stability was evaluated by utilizing the CAE program in order to prevent the risk of damage arising from impact and vibration that are generated during the packaging and transportation process given its material characteristics. CAE is an abbreviation for Computer Applied Engineering for realization by predicting changes at the time of application of virtual physical energy. It is applied by reflecting the physical property conditions and each boundary condition of plaster, and the digital images of the internal and external structure of the work were acquired through 3D scanning and CT analysis for interpretation by executing finite element modeling. When acceleration is applied to the work in the direction of its own weight, the left-right side and the front-rear side, it was possible to confirm a maximum displacement value of 15.24 mm in the head section of the front-rear side direction that has been tilted by approximately 27° from the Y-axis and the largest stress value of 12.46 MPa was at the left ankle section. The corresponding results confirmed that the left ankle section is the most vulnerable area and the section for which precautions need to be exercised and supplemented at the time of transporting the work by means of objective values.

• 한국콘텐츠학회논문지
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• 제22권5호
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• pp.383-392
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• 2022

문화기술은 메타버스와 같이 타 산업과의 융·복합화를 통해 새로운 가치 창출에 기여하고 있다. 정부도 문화콘텐츠산업의 경쟁력 확보를 위해 해당 분야의 연구개발에 적극적으로 투자하고 있다. 이에 본 연구에서는 국가연구개발 과제 중 문화기술의 R&D 효율성을 과제 특성별로 비교 분석하였다. 이를 위해 2016-2019년에 수행된 968개 국가연구개발 과제를 대상으로 자료포락분석과 비모수 검정을 하였다. 분석 결과 기술 분류별로는 문화유산, 문화콘텐츠, 생활문화 순으로 R&D 효율성이 높았다. 연구수행 주체별로는 대학, 민간기업, 공공 연구기관 순으로 R&D 효율성이 높았다. 또한, 타 기관과 협력한 경우 협력하지 않은 경우보다 R&D 효율성이 낮았다. 지역별로는 서울 지역에서 수행된 과제가 타 지역의 과제보다 R&D 효율성이 높았다. 즉, 문화기술분야의 국가연구개발 과제 특성에 따라 R&D 효율성 차이가 존재함을 확인하였다. 이는 문화기술에 대한 국가연구개발 과제를 기획할 때 이러한 특성을 고려하여 전략적으로 추진해야 함을 시사한다.

• Structural Engineering and Mechanics
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• 제88권1호
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• pp.1-12
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• 2023

In this study, forced vibration behavior of a piezo magneto electric sandwich Timoshenko beam is investigated. It is assumed a sandwich beam with porous core and graphene platelet reinforced composite (GPLRC) in facesheets subjected to magneto-electro-elastic and temperature-dependent material properties. The magneto electro platelets are under linear function along with the thickness that includes a cosine function and magnetic and electric constant potentials. The governing equations of motion are derived using modified strain gradient theory for microstructures. The effects of material length scale parameters, temperature change, different distributions of porous, various patterns of graphene platelets, and the core to face sheets thickness ratio on the natural frequency and excited frequency of a sandwich Timoshenko beam are scrutinized. Various size-dependent methods effects such as MSGT, MCST, and CT on the natural frequency is considered. Moreover, the final results affirm that the increase in porosity coefficient and volume fractions lead to an increase in the amount of natural frequency; while vice versa for the increment in the aspect ratio. From forced vibration analysis, it is understood that by increasing the values of volume fraction and the length thickness of GPL, the maximum deflection of a sandwich beam decreases. Also, it is concluded that increasing the temperature, the thickness of GPL, and the initial force leads to a decrease in the maximum deflection of GPL. It is also shown that resonance phenomenon occurs when the natural and excitation frequencies become equal to each other. Outcomes also reveal that the third natural frequency owns the minimum value of both deflection and frequency ratio and the first natural frequency has the maximum.

• Imaging Science in Dentistry
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• 제54권2호
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• pp.121-127
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• 2024

Purpose: Preoperative identification of the intraosseous posterior superior alveolar artery (PSAA) is critical when planning sinus surgery. This study was conducted to determine the distance between the cementoenamel junction and the PSAA, as well as to identify factors influencing the detection of the PSAA on cone-beam computed tomography (CBCT). Materials and Methods: In total, 254 CBCT scans of maxillary sinuses, acquired with 2 different scanners, were examined to identify the PSAA. The distance from the cementoenamel junction (CEJ) to the PSAA was recorded at each maxillary posterior tooth position. Binomial logistic regression and multiple linear regression were employed to evaluate the effects of scanner type, CBCT parameters, sex, and age on PSAA detection and CEJ-PSAA distance, respectively. P-values less than 0.05 were considered to indicate statistical significance. Results: The mean CEJ-PSAA distances at the second molar, first molar, second premolar, and first premolar positions were 17.0±4.0 mm, 21.8±4.1 mm, 19.5±4.7 mm, and 19.9±4.9 mm for scanner 1, respectively, and 17.3±3.5 mm, 16.9±4.3 mm, 18.5±4.1 mm, and 18.4±4.3 mm for scanner 2. No independent variable significantly influenced PSAA detection. However, tooth position (b=-0.67, P<0.05) and scanner type (b=-1.3, P<0.05) were significant predictors of CEJ-PSAA distance. Conclusion: CBCT-based estimates of CEJ-PSAA distance were comparable to those obtained in previous studies involving cadavers, CT, and CBCT. The type of CBCT scanner may slightly influence this measurement. No independent variable significantly impacted PSAA detection.

• Korean Journal of Radiology
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• 제20권5호
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• pp.773-780
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• 2019

Objective: To assess segmental liver stiffness (LS) with MRI before and after endovascular intervention in patients with Budd-Chiari syndrome (BCS). Materials and Methods: Twenty-three patients (13 males and 10 females; mean age, 42.6 ± 12.6 years; age range, 31-56 years) with BCS as a primary liver disease were recruited for this study. Two consecutive magnetic resonance elastography (MRE) examinations were performed before the endovascular treatment. Fifteen patients who underwent endovascular intervention treatment also had follow-up MRE scans within three days after the procedure. LS was measured in three liver segments: the right posterior, right anterior, and left medial segments. Inter-reader and inter-exam repeatability were analyzed with intraclass correlation coefficients (ICCs) and Bland-Altman analysis. Segmental LS and clinical characteristics before and after the intervention were also compared. Results: Within three days of the endovascular intervention, all three segmental LS values decreased: LS of the right posterior segment = 7.23 ± 0.88 kPa (before) vs. 4.94 ± 0.84 kPa (after), LS of the right anterior segment = 7.30 ± 1.06 kPa (before) vs. 4.77 ± 0.85 kPa (after), and LS of the left medial segment = 7.22 ± 0.87 kPa (before) vs. 4.87 ± 0.72 kPa (after) (all p = 0.001). There was a significant correlation between LS changes and venous pressure gradient changes before and after treatments (r = 0.651, p = 0.009). The clinical manifestations of all 15 patients significantly improved after therapy. The MRE repeatability was excellent, with insignificant variations (inter-reader, ICC = 0.839-0.943: inter-examination, ICC = 0.765-0.869). Bland-Altman analysis confirmed excellent agreement (limits of agreement, 13.4-19.4%). Conclusion: Segmental LS measured by MRE is a promising repeatable quantitative biomarker for monitoring the treatment response to minimally invasive endovascular intervention in patients with BCS.

• Journal of Periodontal and Implant Science
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• 제53권5호
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• pp.388-401
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• 2023

Purpose: This study investigated the accuracy of free-hand implant surgery performed by an experienced operator compared to static guided implant surgery performed by an inexperienced operator on an anterior maxillary dental model arch. Methods: A maxillary dental model with missing teeth (No. 11, 22, and 23) was used for this in vitro study. An intraoral scan was performed on the model, with the resulting digital impression exported as a stereolithography file. Next, a cone-beam computed tomography (CBCT) scan was performed, with the resulting image exported as a Digital Imaging and Communications in Medicine file. Both files were imported into the RealGUIDE 5.0 dental implant planning software. Active Bio implants were selected to place into the model. A single stereolithographic 3-dimensional surgical guide was printed for all cases. Ten clinicians, divided into 2 groups, placed a total of 60 implants in 20 acrylic resin maxillary models. Due to the small sample size, the Mann-Whitney test was used to analyze mean values in the 2 groups. Statistical analyses were performed using SAS version 9.4. Results: The accuracy of implant placement using a surgical guide was significantly higher than that of free-hand implantation. The mean difference between the planned and actual implant positions at the apex was 0.68 mm for the experienced group using the free-hand technique and 0.14 mm for the non-experienced group using the surgical guide technique (P=0.019). At the top of the implant, the mean difference was 1.04 mm for the experienced group using the free-hand technique and 0.52 mm for the non-experienced group using the surgical guide technique (P=0.044). Conclusions: The data from this study will provide valuable insights for future studies, since in vitro studies should be conducted extensively in advance of retrospective or prospective studies to avoid burdening patients unnecessarily.