• 대한방사선기술학회지:방사선기술과학
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• 제41권6호
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• pp.595-602
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• 2018

Quality control (QC) of Computed Tomography (CT) devices is based on image quality measurement on AAPM CT phantom which is a standard phantom. Although it is possible to control the accuracy of the CT apparatus, it is expensive and has a disadvantage of low penetration rate. Therefore, in this study, we make image quality measurement phantom at low cost using FFF (Fused Filament Fabrication) type three-dimensional printer and try to analyze the usefulness, compare it with existing standard phantom. To print a phantom, We used three-dimensional printer of the FFF system and PLA (Poly Lactic Acid, density: $1.24g/cm^3$) filament, and the CT device of 64 MDCT (Aquilion CX, Toshiba, Japan). In addition, we printed a phantom using three-dimensional printer after design using various tool based on existing standard phantom. For image quality evaluation, AAPM CT phantom and self-generated phantom were measured 10 times for each block. The measured data were analyzed for significance using the Mannwhiteney U-test of SPSS (Version 22.0, SPSS, Chicago, IL, USA). As a result of the analysis, phantom fabricated with three-dimensional printer and standard phantom showed no significant difference (p>0.05). Furthermore, we confirmed that image quality measurement performance of a phantom using three-dimensional printer is similar to the existing standard phantom. In conclusion, we confirmed the possibility of low cost phantom fabrication using three dimensional printer.

• 한국방사선학회논문지
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• 제17권6호
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• pp.819-825
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• 2023

흉부 CT 검사 조건 중 관전압을 100, 80 kVp, 재구성 알고리즘을 FBP, ASIR-V, DLIR로 변화 적용하여 검사 선량과 화질 변화를 비교 분석해 보았다. 그 결과 기존 관전압 보다 낮은 관전압인 100 kVp 에서 ASIR-V, DLIR 적용 시 선량을 낮추면서 120 kVp, FBP 적용 시와 가장 유사한 화질로 구현. 특히, DLIR 재구성 영상은 모든 관전압에서 SNR, CNR이 우수하였다. 또한, SSIM 지수가 1에 가장 근사하게 분석되어 원본 영상과 가장 유사도가 높은 것을 알 수 있었다. 따라서 반복적으로 흉부 CT 검사를 시행하는 경우 DLIR 적용은 검사 선량을 약 29.7% 감소시킬 수 있어 CT 검사의 가장 큰 문제점인 검사로 인한 피폭을 일부 해결하는 데 도움을 줄 수 있을 것으로 사료된다.

• 한국방사선학회논문지
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• 제16권4호
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• pp.387-394
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• 2022

갑상샘이 포함된 인체모형 팬텀을 이용하여 임상에서 많이 적용하는 NECK CT 프로토콜 중 관전압을 변화 적용하여 스캔 후 Raw data를 이용하여 FBP, ASIR-V, DLIR 재구성기법 적용 영상 획득하여 120 kVp FBP 재구성 영상 기준 DLIR 재구성기법의 유용성을 알아보았다. 그 결과 DLIR 재구성기법 적용 시 CTDIvol 이 감소하였으며, 특히 동일 관전압에서 FBP 적용보다 ASIR-V, DLIR 재구성 시 낮은 선량에서도 기준 스캔 조건으로 획득한 화질에 도달하였다. 또한, SNR, CNR 분석결과 DLIR 재구성 영상이 SNR, CNR 값이 높게 분석되었고, SSIM분석결과 100 kVp, DLIR 재구성 영상이 SSIM 지수가 1에 근사하게 측정되어 원본 영상에 대한 재구성 영상의 유사도가 높은 것으로 분석되었다(p>0.05). 본 연구결과를 활용하여 임상 영상 평가를 시행하여 보완하고 다양한 해부학적 구조에 적용 가능한 알고리즘을 추가 개발한다면 검사 선량을 현재 보다 낮추면서 화질을 유지할 수 있어 임상 적용 시 유용할 것으로 생각된다.

• Tuberculosis and Respiratory Diseases
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• 제57권6호
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• pp.515-521
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• 2004

With the increasing resolution of modern CT scanners, analysis of the larger numbers of images acquired in a lung screening exam or diagnostic study is necessary, which also needs high accuracy and reproducibility. Recent developments in the computerized analysis of medical images are expected to aid radiologists and other healthcare professional in various diagnostic tasks of medical image interpretation. This article is to provide a brief overview of some of computer-aided diagnosis schemes in chest CT.

• 한국방사선학회논문지
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• 제14권7호
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• pp.981-989
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• 2020

본 연구는 Pitch의 변화에 따른 CT 감약계수(CT Number)와 잡음(Noise)의 변화를 정량적으로 측정하고자 자체 제작한 맞춤형 팬텀(Customized Phantom)을 사용하였다. 팬텀을 이용한 영상의 획득을 위해 팬텀 내부는 멸균증류수로 가득 채웠다. 유리관 내부에는 생리식염수와 조영제의 비율을 각각 생리식염수 100%, 400:1, 200:1, 100:1, 50:1로 희석한 용액을 담은 후 영상화하였고, 이때 용액의 희석비율별로 pitch를 0, 0.35, 0.7, 1.05, 1.4의 단계로 나누어 각각 영상화하였다. 희석비율별로 모든 ROI에서 측정한 CT number와 noise 값의 평균이 pitch의 변화에 따라 유의한 차이를 보이는지 검증하고자 일원 배치 분산분석(One-way ANOVA Analysis)과 사후검정을 시행하였다. 실험 결과 각 희석비율별 pitch의 변화에 대한 CT number의 변화는 통계적으로 유의한 차이가 없었지만, noise 값은 pitch의 증가에 따라 증가하는 경향을 보였으며, 통계적으로도 유의한 차이를 보이는 것으로 나타났다. 나선형 영상획득 방식은 pitch에 따라 noise가 유의한 수준으로 달라질 수 있다. 따라서 나선형 영상획득 방식을 적용한 CT 영상의 화질평가 항목과 기준을 설정할 필요가 있을 것이다.

• 핵의학기술
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• 제27권1호
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• pp.47-54
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• 2023

Purpose PET-CT imaging require an appropriate quality assurance system to achieve high efficiency and reliability. Quality control is essential for improving the quality of care and patient safety. Currently, there are performance evaluation methods of UN2-1994 and UN2-2001 proposed by NEMA and IEC for PET-CT image evaluation. In this study, we compare phantom images with the same experiments before and after PET-CT 3D normalization and well counter correction and evaluate the usefulness of quality control. Materials and methods Discovery 690 (General Electric Healthcare, USA) PET-CT equiptment was used to perform 3D normalization and well counter correction as recommended by GE Healthcare. Based on the recovery coefficients for the six spheres of the NEMA IEC Body Phantom recommended by the EARL. 20kBq/㎖ of ¹⁸F was injected into the sphere of the phantom and 2kBq/㎖ of ¹⁸F was injected into the body of phantom. PET-CT scan was performed with a radioacitivity ratio of 10:1. Images were reconstructed by appliying TOF+PSF+TOF, OSEM+PSF, OSEM and Gaussian filter 4.0, 4.5, 5.0, 5.5, 6.0, 6,5 mm with matrix size 128×128, slice thickness 3.75 mm, iteration 2, subset 16 conditions. The PET image was attenuation corrected using the CT images and analyzed using software program AW 4.7 (General Electric Healthcare, USA). The ROI was set to fit 6 spheres in the CT image, RC (Recovery Coefficient) was measured after fusion of PET and CT. Statistical analysis was performed wilcoxon signed rank test using R. Results Overall, after the quality control items were performed, the recovery coefficient of the phantom image increased and measured. Recovery coefficient according to the image reconstruction increased in the order TOF+PSF, TOF, OSEM+PSF, before and after quality control, RCmax increased by OSEM 0.13, OSEM+PSF 0.16, TOF 0.16, TOF+PSF 0.15 and RCmean increased by OSEM 0.09, OSEM+PSF 0.09, TOF 0.106, TOF+PSF 0.10. Both groups showed a statistically significant difference in Wilcoxon signed rank test results (P value<0.001). Conclusion PET-CT system require quality assurance to achieve high efficiency and reliability. Standardized intervals and procedures should be followed for quality control. We hope that this study will be a good opportunity to think about the importance of quality control in PET-CT

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part2
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• pp.808-809
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• 2006

The decrease of the distance between particle centers due to the growth of the sinter necks can be explained by the well known two-particle model. Unfortunately this model fails to provide a comprehensive description of the processes for 3D specimens. Furthermore, there is a significant discrepancy between the calculated and the measured shrinkage because particle rearrangements are not considered. Only the recently developed analysis of the particle movements inside of 3D specimens using micro focus computed tomography $({\mu}CT)$, combined with photogrammetric image analysis, can deliver the necessary experimental data to improve existing sintering theories. In this work, ${\mu}CT$ analysis was applied to spherical copper powders. Based on photogrammetric image analysis, it is possible to determine the positions of all particle centers for tracking the particles over the entire sintering process and to follow the formation and breaking of the particle bonds. In this paper, we present an in-depth analysis of the obtained data. In the future, high resolution synchrotron radiation tomography will be utilized to obtain in-situ data and images of higher resolution.

• 한국의학물리학회지:의학물리
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• 제24권2호
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• pp.99-107
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• 2013

간 전이 암은 이전에는 수술을 통한 외과적 절제가 주요 치료기법이었지만 방사선 치료 기법의 발전으로 인해 점차 방사선치료의 시행이 늘어나고 있다. 18F-FDG PET 영상은 간 전이 암 진단 시 더욱 우세한 민감도와 특이도를 보이며, 치료계획용 CT 영상과 더불어 종양조직의 위치를 정의하는 중요한 영상장비로 자리매김하고 있다. 본 연구에서는 간 전이 암의 18F-FDG PET 영상에 나타난 종양영역을 영상분할기법 적용하였으며 PET영상의 여러 인자들이 영상분할기법들에 미치는 영향을 알아보았다. 2009년부터 2012년까지 방사선 치료를 받은 간전이 환자들 중 18F-FDG PET/CT 촬영을 시행한 13명의 환자들의 치료계획용 CT와 PET/CT 영상을 얻었다. 그 뒤 PET 영상의 관심영역을 설정하기 위하여 3가지 영상 분할 기법인 상대적문턱기법, 기울기기법, 영역성장기법을 적용하였다. 이 결과들을 바탕으로 GTV와 각 영상 기법으로 구현된 종양 영역과 부피 비교를 시행하였으며 영상 분할 기법에 영향을 미치는 영상인자들과의 관계를 회귀 분석하였다. GTV (Gross Tumor Volume)의 평균 부피는 $60.9{\pm}65.9$ cc이며, 40% 상대적문턱값 기법은 $22.43{\pm}35.3$ cc, 50% 상대적문턱값 기법은 $10.11{\pm}17.9$ cc, 영역성장기법은 $32.89{\pm}36.8$ cc, 기울기기법은 $30.34{\pm}35.8$ cc로 나타났다. 기존의 GTV와 가장 유사한 영역을 나타낸 영상 분할 기법은 영역성장기법 이었다. 이 영역성장기법에 영향을 미치는 영상인자를 정량적으로 분석하기 위해 표준화 계수 ${\beta}$값을 이용하였으며, GTV의 크기, $TumorSUV_{MAX/MIN}$, $SUV_{max}$, TBR 순으로 나타났다. 이와 같은 PET 영상인자를 반영한 영상 분할 기법을 이용해서 종양 영역을 정의한다면 보다 정확하고 일관성 있는 종양그리기를 수행할 수 있으며 궁극적으로 종양에 최적화된 방사선량을 투여할 수 있을 것이다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제36권4호
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• pp.262-269
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• 2010

Introduction: Accurate diagnosis and treatment planning are very important for orthognathic surgery. A small error in diagnosis can cause postoperative functional and esthetic problems. Pre-existing 2-dimensional (D) chephalogram analysis has a high likelihood of error due to its intrinsic and extrinsic problems. A cephalogram can also be inaccurate due to the limited anatomic points, superimposition of the image, and the considerable time and effort required. Recently, an improvement in technology and popularization of computed tomography (CT) provides patients with 3-D computer based cephalometric analysis, which complements traditional analysis in many ways. However, the results are affected by the experience and the subject of the investigator. Materials and Methods: The effects of the sources human error in 2-D cephalogram analysis and 3-D computerized tomography cephalometric analysis were compared using Simplant CMF program. From 2008 Jan to 2009 June, patients who had undergone CT, cephalo AP, lat were investigated. Results: 1. In the 3 D and 2 D images, 10 out of 93 variables (10.4%) and 11 out 44 variables (25%), respectively, showed a significant difference. 2. Landmarks that showed a significant difference in the 2 D image were the points frequently superimposed anatomically. 3. Go Po Orb landmarks, which showed a significant difference in the 3 D images, were found to be the artificial points for analysis in the 2 D image, and in the current definition, these points cannot be used for reproducibility in the 3 D image. Conclusion: Generally, 3-D CT images provide more precise identification of the traditional cephalometric landmark. Greater variability of certain landmarks in the mediolateral direction is probably related to the inadequate definition of the landmarks in the third dimension.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.2352-2355
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• 2003

In recent yeas, studies on computer aided diagnosis (CAD) using image analysis on CT images have been conducted with respect to various diseases. Extracting ground-glass opacities (GGO) on lung CT images is one of such subjects, though it has not found an established method yet. If the region of ground-glass opacities is large on CT images, it can be detected without much difficulty. On the other hand, if the region is small, it is still difficult to find it exactly. In the latter case, increasing overlooking possibility cannot be avoided according to smaller size of the region. To solve this difficulty, this paper proposes an automatic technique for extracting ground-glass opacities on lung CT images employing some statistical parameters of a gray level histogram and a differential histogram. The proposed technique is applied to some lung CT images in the performed experiment. The results are shown with discussion on future work.