• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 춘계학술대회
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• pp.141-144
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• 1997

Femoral neck anteversion is the angle between the neck and the knee axis projected on a plane perpendicular to the longitudinal axis. Conventional methods that use cross-sectional Computed Tomography(CT) images to estimate femoral anteversion have several problems because of the complex 3D structure of the femur. These are the ambiguity of defining the longitudinal axis, the femoral neck axis and condylar line, and the dependence on patient positioning. Especially the femoral neck axis that is known as a major source of error is hard to determine from a single or multiple 2D transverse images. So we developed a new method for measuring femoral anteversion by 3D modeling method. In this method, femoral head is modeled as a sphere. The center of femoral neck is the mid-point of the 2D reconstructed oblique image in the femoral neck part. Then neck axis is a line connecting foregoing two centers. We model the longitude of femur as a cylinder, and the long axis is defined from the fitted cylinder. The knee axis which is tangent to the back of the femoral condyles is easily determined by table-top method. By the definition of femoral anteversion, the femoral anteversion is easily calculated from this model.

• Journal of International Society for Simulation Surgery
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• 제4권1호
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• pp.9-12
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• 2017

Purpose Surgery for separating craniopagus twins involves many critical issues owing to complex anatomical features. We demonstrate a 3D printed model and virtual reality (VR) technologies that could provide valuable benefits for surgical planning and simulation, which would improve the visualization and perception during craniopagus surgery. Material & Methods We printed a 3D model extracted from CT images of craniopagus patients using segmentation software developed in-house. Then, we imported the 3D model to create the VR environment using 3D simulation software (Unity, Unity Technologies, CA). We utilized the HTC Vive (HTC & Valve Corp) head-mount-display for the VR simulation. Results We obtained the 3D printed model of craniopagus patients and imported the model to a VR environment. Manipulating the model in VR was possible, and the 3D model in the VR environment enhanced the application of user-friendly 3D modeling in surgery for craniopagus twins. Conclusion The use of the 3D printed model and VR has helped understand complicated anatomical structures of craniopagus patients and has made communicating with other medical surgeons in the field much easier. Further, interacting with the 3D model is possible in VR, which enhances the understanding of the craniopagus surgery as well as the success rate of separation surgery while providing useful information on diagnosing and surgery planning.

• Journal of Advanced Marine Engineering and Technology
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• 제37권8호
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• pp.862-868
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• 2013

직조 형태의 복합재료의 파손 메커니즘은 복합적이다. 지금까지 평직 복합재료를 대상으로 많은 연구가 이루어졌으나, 파괴 저항성 거동은 아직도 표준화 되지 못한 실정이다. 또한 섬유배열방향에 따라 다른 거동을 보인다. 그래서 하중방향에 대한 섬유배열방향에 따른 파괴 저항성 평가가 필요하다. 이에 본 연구에서는 평직 CFRP 복합재료를 대상으로 다양한 섬유배열방향에 따른 파손강도 및 파괴 저항성 평가를 수행하였다.(섬유배열 방향: $0^{\circ}$, $15^{\circ}$, $30^{\circ}$, $45^{\circ}$) CT 시험편을 이용하여 모드 I 조건으로 시험을 수행하였다.

• Advances in pediatric surgery
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• 제13권2호
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• pp.144-154
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• 2007

Liver tumors in children are rare, relatively complex, and encompass a broad spectrum of disease processes. This study reviews our experience of liver tumors during the last 10 years. Medical records of 36 cases of liver tumors in children, treated at Samsung Medical Centers, from October 1994 to December 2005, were reviewed in this study. We analyzed disease characters and survival rates as a whole and by specific disease. The median age was 3.6 years. Male and female ratio was 1:1. The most common symptom was the palpable mass in 15 cases. Others were abdominal distension in 9 cases, jaundice in 2, vomiting in 2, weight loss in 2, and pubic hair growth in 1. CT or US and liver biopsy were performed for diagnosis. There were 28 malignant tumors: malignant rhabdoid tumor (1 case), hepatocellular carcinoma (3 cases), hemangioendothelioma type II (3 cases), angiosarcoma (1 case), and hepatoblastoma (20 cases). Eight tumors were benign; hepatic adenoma (1 case), focal nodular hyperplasia (2 cases), hemangioendothelioma type I (2 cases), mesenchymal hamartoma (3 cases). In this study the clinical characteristics were not different from the other reports. Liver transplantation was performed in 3 cases-1 with hepatoblastoma and 2 with hepatocelleular carcinoma. Accurate and early diagnosis, and individualized multimodality therapeutic approaches might be important for better outcome.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제22권3호
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• pp.351-355
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• 2000

두경부 관통성 외상의 기본적 처치는 먼저 초기 단계에서 환자의 정확한 병력 및 이학 검사, 호흡 억제 유무 평가, 중대한 출혈 유무의 평가 등을 시행한다. 중대한 출혈의 평가는 외부 출혈 유무, 급속히 커지는 혈종 유무, 혈류역학적으로 불안정한 생징후를 보이는 경우, 맥박 소실, 저혈량성 쇼크의 소견, 혈종격동이나 혈흉 소견이 있는 경우 등이다. 이러한 경우 즉각적인 외과적 처치를 시행해야 한다. 중대한 출혈의 소견을 보이지는 않지만 혈관 손상이 의심되거나 가능성이 높다고 생각되는 경우로는 혈류 잡음, 삽입 이물질이 큰 혈관에 근접 위치한 경우, 맥박 소실이나 중추 신경학적 문제가 발생한 경우 등이 해당된다. 이때는 혈관조영술과 CT촬영을 시행한 후 보존적으로 관찰을 할지 외과적 처치를 시행할지를 결정한다. 이때도 외과적 처치가 필요한 경우 지체없이 시행한다. 또한 두경부 이몰 삽입에 의해 환자가 자신의 생명에 심각한 위협을 받았다고 느끼기때문에 정신적인 충격을 해소해 주어야 한다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제47권5호
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• pp.382-387
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• 2021

Objectives: Zygomatic complex (ZMC) fractures comprise up to 40% of all facial fractures. Misaligned bone fragments and misplaced fixation hardware traditionally detected postoperatively on plain radiographs of the skull might require re-operation. The intraoperative O-Arm (Medtronic, USA) is a three-dimensional (3D) computed tomographic imaging system. Materials and Methods: This retrospective single-center study evaluated the utility of O-Arm scanning during corrective surgeries for ZMC and zygomatic arch (ZA) fractures from 2018 to 2020. Three females and 16 males (mean age, 31.52 years; range, 22-48 years) were included. Fracture instability (n=6) and facial deformity (n=15) were the most frequent indications for intraoperative 3D O-Arm scan. Results: The images demonstrated that all fracture lines were properly reduced and fixed. Another scan performed at the end of the fixation or reduction stage, however, revealed suboptimal results in five of the 19 cases, and further reduction and fixation of the fracture lines were required. Conclusion: Implementation of an intraoperative O-Arm system in ZMC and ZA fracture surgeries assists in obtaining predictable and accurate results and obviates the need for revision surgeries. The device should be considered for precise operations such as ZMC fracture repairs.

• 한국운동역학회지
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• 제31권3호
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• pp.155-161
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• 2021

Objective: There is a lack of studies using the 3D-2D image registration techniques on the mechanism of a shoulder injury for ice hockey players. This study aimed to analyze in vivo 3D glenohumeral joint arthrokinematics in collegiate ice hockey athletes and compare shoulder scaption with or without a hockey stick using the 3D-2D image registration technique. Method: We recruited 12 male elite ice hockey players (age, 19.88 ± 0.65 years). For arthrokinematic analysis of the common shoulder abduction movements of the injury pathogenesis of ice hockey players, participants abducted their dominant arm along the scapular plane and then grabbed a stick using the same motion under C-arm fluoroscopy with 16 frames per second. Computed tomography (CT) scans of the shoulder complex were obtained with a 0.6-mm slice pitch. Data from the humerus translation distances, scapula upward rotation, anterior-posterior tilt, internal to external rotation angles, and scapulohumeral rhythm (SHR) ratio on glenohumeral (GH) joint kinematics were outputted using a MATLAB customized code. Results: The humeral translation in the stick hand compared to the bare hand moved more anterior and more superior until the abduction angle reached 40°. When the GH joint in the stick hand was at the maximal abduction of the scapula, the scapula was externally rotated 2~5° relative to 0°. The SHR ratio relative to the abduction along the scapular plane at 40° indicated a statistically significant difference between the two groups (p < 0.05). Conclusion: With arm loading with the stick, the humeral and scapular kinematics showed a significant correlation in the initial section of the SHR. Although these correlations might be difficult in clinical settings, ice hockey athletes can lead to the movement difference of the scapulohumeral joints with inherent instability.

• 대한방사선기술학회지:방사선기술과학
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• 제41권6호
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• pp.561-566
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• 2018

Field-in-Field Technique is applied to the radiation therapy of breast cancer patients, and it is possible to compensate the difference in breast thickness and deliver uniform dose in the breast. However, there are several fields in the treatment field that result in a more complex dose delivery than a single field dose delivery. If the patient's respiration is irregular during the delivery of the dose by several fields and the change of respiration occurs, the dose distribution in the breast changes. Therefore, based on the computed tomography images of breast cancer patients, a human model was created by using a 3D printer (Builder Extreme 1000) to describe the volume in the same manner. A computerized tomography (CT) of the human body model was performed and a treatment plan of 260 cGy / fx was established using a 6-MV field-in-field technique using a computerized treatment planning system (Eclipse 13.6, Varian, USA). The distribution of the dose in the breast according to the change of the respiration was measured using a moving phantom at 0.1 cm, 0.3 cm, 0.5 cm amplitude, using a MOSOXIDE Silicon Field Effect Transistor (MOSFET, Best Medical, Canada) Were measured and compared. The distribution of dose in the breast according to the change of respiration showed similar value within ${\pm}2%$ in the movement up to 0.3 cm compared to the treatment plan. In this experiment, we found that the dose distribution in the breast due to the change of respiration when the change of respiration was increased was not much different from the treatment plan.

• Restorative Dentistry and Endodontics
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• 제44권2호
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• pp.16.1-16.12
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• 2019

Objectives: The upper molars generally have three roots; therefore, different combinations of fusion can occur, increasing the possibility of finding more complex root canal systems. The purpose of this study was to evaluate the prevalence and characterization of fused roots in first and second maxillary molars using cone-beam computed tomography (CBCT) in a Colombian population. Materials and Methods: A total of 1274 teeth were evaluated, of which 534 were maxillary first molars and 740 were maxillary second molars. Axial sections were made at the cervical, middle, and apical levels to determine the prevalence of root fusion and the types of fusion. Results: Overall, 43% of the molars (n = 551) presented some type of fused root. Root fusion was present in 23.4% of the maxillary first molars. The most frequent type of fused root was type 3 (distobuccal-palatal; DB-P) (58.9%). Root fusion was observed in 57.6% of the maxillary second molars, and the most prevalent type of fused root was type 6 (cone-shaped) (45.2%). Of the maxillary molars, 12.5% were classified as C-shaped. Conclusion: Within the limitations of this study, there was a high prevalence of fused roots in maxillary molars in the Colombian population, mainly in the maxillary second molars. In first molars, the most common type of fused root was type 3 (DB-P) and in second molars, the most common type was type 6 (cone-shaped). Additionally, molars with root fusion presented variation at different levels of the radicular portion, with implications for treatment quality.

• 미생물학회지
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• 제47권2호
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• pp.117-123
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• 2011

본 연구는 human rotavirus (HRV)의 검출법을 최적화하기 위해 real-time RT-PCR과 세포 배양법을 이용하여 여러 가지 탈리 농축법을 비교 및 평가하는 것을 목적으로 하였다. 채소류 중 배추, 상추, 깻잎을 선정하여 바이러스 희석액을 접종하고 탈리액 비교를 위하여 buffer A (100 mM Tris-HCl, 50 mM glycine, 3% beef extract, pH 9.5)와 buffer B (250 mM Threonine, 300 mM NaCl, pH 9.5)를 이용하여 탈리하였고, 농축방법을 비교하기 위하여 PEG (polyethylene glycol) 침전법 또는 filtration [Nanoceram filter$^{(R)}$ (Argonide corporation)]을 이용하여 농축하였다. 또한 바이러스의 감염성 평가를 위하여 MA-104 cell을 배양하여 탈리, 농축 방법을 거쳐 회수된 HRV를 접종하고 1, 48, 72, 96, 120, 144, 168시간 후 세포를 수거하여 real-time RT-PCR을 시행하고 세포병변을 관찰하였다. 탈리 용액은 buffer A가 회수율 29.54%로 buffer B의 18.32%보다 더 뛰어난 탈리효과를 보였으며 농축방법을 비교했을 때 filtration 방법이 회수율 51.89%를 나타내며 PEG 침전법에 비해서 바이러스의 농축에 효과적이었으며 검출 소요시간이나 간단한 과정 면에서 효율적이었다. ICC/real-time RT-PCR을 시행하였을 때 세포병변 72시간 후부터 나타나기 시작했지만 Ct value는 48시간부터 감소하기 시작하여 더 빠른 시간 내에 감염성을 평가할 수 있었다. 따라서, filtration과 integrated/cell culture real-time RT-PCR을 이용하면 기존의 검출방법보다 빠른 시간 내에 바이러스 검출이 가능할 것으로 여겨진다.