• Proceedings of the Korean Information Science Society Conference
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• 2012.06b
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• pp.178-180
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• 2012

협업은 둘 이상의 사람들이 하나의 업무 또는 목적을 달성하기위해 공동으로 협력하여 일하는 것이다. 최근 개인 및 조직 간 협업 범위가 공동분석, 데이터 연계, 서비스 조합 등으로 확장되고 대용량 데이터 공유 및 실시간 연계분석 활동이 증대되면서 협업 지향적인 시스템 설계와 개발이 중요시 되고 있다. 특히 스마트워크와 지능화된 협업 기반은 데이터, 프로세스, 서비스, 사람 간의 다차원 연계와 실시간 활용, 의미 기반의 기계적 협력을 전재로 하고 있다. 본 연구에서는 Data, Process, Service, People 측면의 4가지 계층으로 전사적 자원을 설계하고 메타 메타데이터 기반의 온톨로지 분석을 통해 자원 간의 연계와 조합을 지원하는 시스템을 설계했다. Data 계층은 프로세스별 Input, Output 정보를 식별하여 Data의 메타 정보를 정의하고 이를 검색 에이전트가 색인하여 모델링에 참조할수록 한다. Process 계층은 BPMN모델을 확장한 exCPM의 개선 모델을 바탕으로 프로세스를 수행주체 간, 정보공유측면에서 프로세스를 분석했다. Service 계층은 협업지향적인 프로세스를 구성하는 컴포넌트를 서비스로 인식하고 프로파일을 통해 협업을 위한 검색과 프로세스를 연계지원하도록 설계 했다. 마지막으로 People계층은 자원, 프로세스, 서비스 등 시스템에 관여하는 참여자들의 메타정보를 정의하고 이를 온톨로지 기반의 모델에 통합하여 자동 검색되도록 설계했다. 이를 통해 프로세스와 서비스 측면에서 협업을 요구하는 에이전트와 일반 검색 사용자들이 프로세스 간 협업 자원을 파악하고 상호 관계를 분석할 수 있도록 하는 한편, 프로세스를 지원하는 컴포넌트와 서비스 간의 자동적인 조합을 통해 통합적 자원 협력과 실시간 협업 지원 기반을 제시했다.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 1996.04a
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• pp.213-216
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• 1996

R'||'&'||'D project management is a process of decisions concerned with the achievement of goals of objectives. Especially, defense R'||'&'||'D project planning is the key in the successfull management of defense development. The defense project managers are constantly having to perform "what if\ulcorner" exercise, such as what if the project is extended out for an additional cost\ulcorner In this reserch, we developed a schedule-cost analysis model based upon Critical Path Method(CPM) and Venture Evaluation and Review Technique(VERT) for schedule-cost trade off analysis defense R'||'&'||'D projects. In the first step, a deterministic model is developed as a heuristic which deterministic model is developed as a heuristic which determines the schedule extension and reduction cost as a function desired schedule. In the second step, a stochastic network simulation model is developed to analyse the project risk (sucess and failure). The expected time and cost can be determined for desired schedule under the assumptions of stochastic arc data (time and cost) with a various precedence relationships. This model provides the defense R'||'&'||'D managers with an estimated and expected cost for curtailing or extending a project a given amount of time. The effectiveness and efficiency of the proposed methods, a heuristic and stochastic networks simulations, have been demonstrated through examples.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.13 no.2
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• pp.1-7
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• 2014

Recent experimental observations support the hypothesis that mechanical stimuli play a role in regulating the specialized molecular expression of articular cartilage in vitro and in vivo. Other studies have demonstrated that the continuous passive motion(CPM)bioreactor for whole joints can provide a platform for possible future in vitro studies and applications, including possible interactions of bio-mechanical and biochemical signals. In this study, we have developed acustom-made bioreactor capable of bending and stretching with circular type motion, and a biomimetic knee joint model, using a 3D printer. This system could be used to investigate the effects of rehabilitative joint motion of dynamic culture.

• The Korean Journal of Nuclear Medicine
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• v.32 no.1
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• pp.89-98
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• 1998

The search for tumor-avid agents for use in nuclear medicine imaging is an ongoing field of importance. The purpose of this study was to determine the affinity for radio labeled vitamin $B_{12}$ by a wide histologic variety of tumor types in mice. Seventeen different types of tumor were grown subcutaneously in female Balb/C or Balb nu/nu(nude) mice. When the tumors reached about 1 cm in diameter, mice were injected intraperitoneally with $^{57}Co$-vitamin $B_{12}$. Twenty-four hours later, the mice were sacrificed. Organs and tissues were removed, weighed, and activity per mg determined by gamma counter. Values represented cpm/mg tissue that was normalized to 20 grams body weight for each mouse. A wide variety of tumor types showed significant uptake and concentration of $^{57}Co$-vitamin $B_{12}$, as evidenced by tumor:tissue activity ratios. For many tissues of great importance in terms of background(bone, muscle, blood), the tumor:tissue activity ratios of uptake were high. These data strongly suggest that further efforts to evaluate the utility of radio labeled adducts of vitamin $B_{12}$ for clinical use in oncologic imaging are warranted.

• Journal of the Society of Naval Architects of Korea
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• v.36 no.3
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• pp.83-92
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• 1999

In this paper, the fluid-structure interaction of large floating structures has been rigorously analyzed and the shear effect on the structural deformation has been investigated in oblique waves. A constant panel method(CPM) based on the Green function method is implemented for computing the hydrodynamic pressure, while a finite element method(FEM) is applied for the structural response based on the Mindlin plate theory with including shear deformation. In order to validate the method, we compared numerical results with experimental ones of Mega Float carried out by Yago & Endo in head waves. General behavior shows good agreement but the local displacement at the ends is slightly different. The numerical results show that the radiation pressure due to the fluid-structure interaction is locally larger than that of wave excitation and mooring devices greatly reduce the response. It is observed that the shear effects among the total deformation constitutes about 4% in the case of Mega Float in oblique waves.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.112-112
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• 2011

오늘날 우리 사회의 생활과 문화의 질이 향상됨에 따라 공공 및 개인의 안전과 건강에 대한 관심이 증대되고 있다. 특히, 재난과 비상사태는 생명에 대한 희생뿐만 아니라 훨씬 더 심각한 경제적인 결과를 초래한다. 이러한 응급사태에 개비하여 적절히 준비되지 않았거나 재난의 예방 및 완화시킬 방법을 가지고 있지 못한다면 도시의 발전적인 프로젝트는 예고 없이 도시를 강타하는 재난 및 비상사태에 의해 무산되고 만다. 이러한 여건 하에 재난과 응급사고를 효율적으로 대처하는 응급처치와 서비스에 대한 급격한 관심과 함께 일정한 결정적 대응시간 내에 각종사고와 재해로부터 방어할 수 있는 공공서비스에 대한 필요성이 크게 증가되었다. 본 연구에서는 신고, 응급구조, 환자이송 등 도시의 병원 전 단계 의료환경에 대해서 조사하였다. 본 연구의 목적은 반응시간과 출동거리를 분석함으로써, 응급사고에 즉시 응급구조서비스를 제공하기 위해 안전센터(119센터)의 최적 입지를 확인하는 것이다. 이를 위해서 사고발생, 반응시간, 출동거리 등을 응급의료 활동과 관련된 연구논문, 대상지 전역의 소방기록물과 출동일지 등의 통계자료를 활용하여 신속한 응급의료 서비스를 위한 패턴을 분석 하였다. 또한 응급구조대의 조직과 활동의 분석을 통해 응급의료시설의 최적 입지설정을 위한 제도적 개선대안을 마련해 보았다. 대상지 연구를 위해, 구조활동 및 소방서비스의 최근 통계자료의 조사를 통해 진주시의 모든 119센터의 입지와 응급의료서비스 및 사고발생 현황을 나타내었다. 자료 분석을 위해서 SPSS14.0을 사용하였으며, 지역의 특성 분포, 안전센터별 대응시간, 이송시간 등을 소방 GPS시스템과 입지할당모형 중 Center Point Model(CPM)을 적용하였다. 결과적으로 본 연구를 통해 대상지역의 119안전센터의 서비스 질이 나쁜 지역을 지리학적인 관점에서 최적 입지/배분 패턴의 설정을 통해 확인할 수 있었으며, 이를 통해 미래 응급의료서비스의 효율적인 입지/배분을 통해 공공 및 개인의 안전과 건강에 기여할 수 있을 것으로 기대된다.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2005.06a
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• pp.231-238
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• 2005

On the basis of flow resistance theory the conceptual model and related mathematical descriptions is proposed for resistance modeling of groundwater flow in CPM(continuum Porous medium), DFN(discrete fracture network) and fractured-porous medium. The proposed model is developed on the basis of finite volume method assuming steady-state, constant density groundwater flow. The basic approach of the method is to evaluate inter-block flow resistance values for a staggered grid arrangement, i.e. fluxes are stored at cell walls and scalars at cell centers. The balance of forces, i.e. the Darcy law, is utilized for each control volume centered around the point where the velocity component is stored. The transmissivity (or permeability) at the interface is assumed to be the harmonic average of neighboring blocks. Flow resistance theory was utilized to relate the fluxes between the grid blocks with residual pressures. The flow within porous medium is described by three dimensional equations and that within an individual fracture is described by a two dimensional equivalent of the flow equations for a porous medium. Newly proposed models would contribute to develop flow simulation techniques with various matrix characteristics.

• Journal of the Korean Society of Physical Medicine
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• v.9 no.1
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• pp.45-53
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• 2014

PURPOSE: In this study, we tried to find out what kind of exercise was more effective in sleep disorder by comparing melatonin in blood after applying low intensity with high intensity exercise to sleep disordered rats induced by experiment. METHODS: We used male Sprague-Dawley rats which were 8weeks old and weighted 300g. They were supplied with water and food without any restriction. We kept the room temperature at $25^{\circ}C$ and controld the length of day and night in 12 hours blocks, respectively. We divided the rats 60 into 2 groups. To one group we applied low intensity exercise, and to the other we applied high intensity exercise for 15minutes per day over a period of 4 weeks. We extracted the blood from abdominal aorta before, after exercise, moved into EDTA tube, performed centrifugation. We decanted the serum $200{\mu}l$ from the blood into microcentrifuge tube by samples and moved into polypropylene culture tubes with micro pipette. We split enzyme solution $50{\mu}l$ into the tubes with melatonin direct kits and make them react at $37^{\circ}C$ for 2 hours. We split assay buffer $50{\mu}l$ into each tube and mixed melatonin tracer $50{\mu}l$ and melatonin antiserum $50{\mu}l$, respectively. After we made them react in room temperature, we decanted the superficial layer with a centrifuge and measured the activity for 1 minute by competitive method with ${\gamma}$-counter equipment. We draw a standard curve through logit-log graph with CPM(counts per minute) and counted the melatonin by B/B0. We conducted independent t-test to examine the homogeneous of melatonin value of before low-intensity and high-intensity exercise. We performed paired t-test to compare before and after low-intensity and high-intensity exercise, respectively. We carried out independent t-test to compare melatonin value after low-intensity and high-intensity exercise. Significance level was .05. RESULTS: The results were as follows; firstly melatonin was more increased in the group who was exposed to high intensity exercise when we compared before to after high and low intensity exercise, respectively. Secondly, high intensity exercise was more effective than low intensity exercise when we compared the two. CONCLUSION: In conclusion, secretion of melatonin which is the material of sleep improvement could be promoted by high intensity exercise. Low intensity exercise acted as a stress rather than improving sleep and had a negative effect on the secretion of melatonin because the melatonin was affected by stress.