• Title/Summary/Keyword: COVID-19 Outbreak

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Genomic epidemiology and surveillance of zoonotic viruses using targeted next-generation sequencing (표적화 차세대염기서열분석법을 이용한 인수공통 바이러스의 유전체 역학과 예찰)

  • Seonghyeon Lee;Seung-Hwan Baek;Shivani Rajoriya;Sara Puspareni;Won-Keun Kim
    • Korean Journal of Veterinary Service
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    • v.46 no.1
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    • pp.93-106
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    • 2023
  • Emerging and re-emerging zoonotic viruses become critical public health, economic, societal, and cultural burdens. The Coronavirus disease-19 (COVID-19) pandemic reveals needs for effective preparedness and responsiveness against the emergence of variants and the next virus outbreak. The targeted next-generation sequencing (NGS) significantly contributes to the acquisition of viral genome sequences directly from clinical specimens. Using this advanced NGS technology, the genomic epidemiology and surveillance play a critical role in identifying of infectious source and origin, tracking of transmission chains and virus evolution, and characterizing the virulence and developing of vaccines during the outbreak. In this review, we highlight the platforms and preparation of targeted NGS for the viral genomics. We also demonstrate the application of this strategy to take advantage of the responsiveness and prevention of emerging zoonotic viruses. This article provides broad and deep insights into the preparedness and responsiveness for the next zoonotic virus outbreak.

Forecasting the Environmental Change of Technological Innovation System in South Korea in the COVID-19 Era

  • Kim, Youbean;Park, Soyeon;Kwon, Ki-Seok
    • Asian Journal of Innovation and Policy
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    • v.9 no.2
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    • pp.133-144
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    • 2020
  • Korean economy has experienced a very rapid growth largely due to the change of the innovation system since the last half century. The recent outbreak of COVID-19 impacts the global economy as well as Korea's innovation system. In order to understand the influence of the shock to the Korean technological system, we have forecast the future of the system combining qualitative and quantitative techniques such as expert panel, cross impact analysis, and scenario planning. According to the results, we have identified 39 driving forces influencing the change of Korea's technological innovation system. Four scenarios have been suggested based on the predetermined factors and core uncertainties. In other words, uncertainties of emergence of the regions and global value chains generate four scenarios: regional growth, unstable hope, returning to the past, and regional conflicts. The 'regional growth' scenario is regarded as the most preferable, whereas the 'regional conflicts' scenario is unavoidable. In conclusion, we put forward some policy implications to boost the regional innovation system by exploiting the weakened global value chains in order to move on to the most preferable scenario away from the return to the past regime.

Effectiveness of E-Training, E-Leadership, and Work Life Balance on Employee Performance during COVID-19

  • WOLOR, Christian Wiradendi;SOLIKHAH, Solikhah;FIDHYALLAH, Nadya Fadillah;LESTARI, Deniar Puji
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.10
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    • pp.443-450
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    • 2020
  • This study aims to add insight into the effectiveness of e-training, e-leadership, work-life balance, and work motivation on millennial generation employees' performance in today's work life amid the outbreak of the COVID-19 pandemic that requires to work more online. Unlike previous generations, millennials are technology-literate, intent on succeeding quickly, give up easily, and seek instantaneous gratification. The population in this study are millennial generation employees at one of Honda motorcycle dealers in Jakarta, Indonesia. The number of samples collected was 200. The sampling technique used is the side probability method, with proportional random sampling technique. The research method used is an associative quantitative approach through survey methods and Structural Equation Modeling. Data were collected through questionnaires distributed to millennial generation employees, with results then processed through the Lisrel 8.5 program. The results of this study show, first, that e-training, e-leadership, and work-life balance have positive effect on work motivation. Second, e-training, e-leadership, work-life balance, and work motivation have positive effect on employees' performance. The findings indicate that companies must pay attention to the factors of e-training, e-leadership, and work-life balance to keep employees motivated and to maintain optimal employee performance, especially during the COVID-19 pandemic through working online.

Triggering of Herding Instincts due to COVID-19 Pandemic in Pakistan Stock Exchange

  • JABEEN, Shaista;RIZAVI, Sayyid Salman;NASIR, Adeel
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.10
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    • pp.207-218
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    • 2021
  • The present research intends to examine the herding aspect during the COVID-19 outbreak. The study is conducted to achieve specific objectives, so the underlying sampling technique is purposive sampling. The considered data source is the Pakistan Stock Exchange (PSX). Daily stock prices of 528 listed companies in PSX have been taken from the official website of PSX from 1998 to 2021. The current study envisions investigating the herding aspects for pre-pandemic and the time covering the pandemic period. The study has also targeted ten sectors of PSX. The present study's motive is to investigate investors' herding prospects before and during the pandemic in the Pakistan Stock Exchange (PSX) and its selected sectors. Daily closing stock prices of listed companies have been collected from the official website of PSX to calculate the stock returns. The Cross-Sectional Absolute Deviation (CSAD) has been used as a herding measure. Findings revealed that herding has not been observed in PSX during both time spans and even not during the bullish and bearish trends. However, robust sectoral evidence has been observed during the pandemic. It implies that investors in PSX tend to follow the crowd irrespective of making their own decisions to avoid further losses.

Being a front-line dentist during the Covid-19 pandemic: a literature review

  • Fallahi, Hamid Reza;Keyhan, Seied Omid;Zandian, Dana;Kim, Seong-Gon;Cheshmi, Behzad
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.12.1-12.9
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    • 2020
  • Coronavirus is an enveloped virus with positive-sense single-stranded RNA. Coronavirus infection in humans mainly affects the upper respiratory tract and to a lesser extent the gastrointestinal tract. Clinical symptoms of coronavirus infections can range from relatively mild (similar to the common cold) to severe (bronchitis, pneumonia, and renal involvement). The disease caused by the 2019 novel coronavirus (2019-nCoV) was called Covid-19 by the World Health Organization in February 2020. Face-to-face communication and consistent exposure to body fluids such as blood and saliva predispose dental care workers at serious risk for 2019-nCoV infection. As demonstrated by the recent coronavirus outbreak, information is not enough. During dental practice, blood and saliva can be scattered. Accordingly, dental practice can be a potential risk for dental staff, and there is a high risk of cross-infection. This article addresses all information collected to date on the virus, in accordance with the guidelines of international health care institutions, and provides a comprehensive protocol for managing possible exposure to patients or those suspected of having coronavirus.

Repurposing Screens of FDA-Approved Drugs Identify 29 Inhibitors of SARS-CoV-2

  • Ku, Keun Bon;Shin, Hye Jin;Kim, Hae Soo;Kim, Bum-Tae;Kim, Seong-Jun;Kim, Chonsaeng
    • Journal of Microbiology and Biotechnology
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    • v.30 no.12
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    • pp.1843-1853
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    • 2020
  • COVID-19, caused by the novel coronavirus SARS-CoV-2, has spread globally and caused serious social and economic problems. The WHO has declared this outbreak a pandemic. Currently, there are no approved vaccines or antiviral drugs that prevent SARS-CoV-2 infection. Drugs already approved for clinical use would be ideal candidates for rapid development as COVID-19 treatments. In this work, we screened 1,473 FDA-approved drugs to identify inhibitors of SARS-CoV-2 infection using cell-based assays. The antiviral activity of each compound was measured based on the immunofluorescent staining of infected cells using anti-dsRNA antibody. Twenty-nine drugs among those tested showed antiviral activity against SARS-CoV-2. We report this new list of inhibitors to quickly provide basic information for consideration in developing potential therapies.

An Analysis of the Differences of the Self-Service Research Issues and Trends before and after COVID-19 Pandemic: A Bibliometrics Approach by Using Citespace (셀프서비스 연구 이슈와 추세에 대한 코로나-팬데믹 발생 전후 차이 분석: Citespace를 이용한 계량서지학적 접근)

  • Wu, Haoxi;Joon, Koh
    • Journal of Information Technology Services
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    • v.21 no.6
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    • pp.53-72
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    • 2022
  • As a trend of modern service industry, self-service has been widely concerned by all walks of life, but there is a lack of literature on systematic management of the overall research in this field. Recently, people's lifestyle has been forced to change due to the influence of COVID-19, while there have been some changes in the field of self-service research. Based on the Web of Science data source, this study takes the literature of self-service field before and after the outbreak of COVID-19 as the research object, and summarizes the development process, research status and future research trend of self-service field through the Citespace visualization tool. The research shows that firstly, academic circles continue to be enthusiastic about self-service field research, cooperation between countries is becoming more and more diversified. Secondly, the communication between researchers is becoming more and more intensive, and the cooperation between different disciplines gradually becomes the mainstream. Third, related research gradually shifted to the practical application of technology, the research perspective gradually shifted from the initial traditional retail perspective industries such as tourism services. Finally, the role of customer experience and participation behavior in self-service process is gradually emphasized.

Depression Management System for Single-Person Households In The Era of COVID-19 Pandemic (코로나 팬데믹 시대에서 1인 가구의 우울증 관리 체계 시스템)

  • Hwangbo, Je-Seong;Kim, Ho-Yoon;Lee, Won-Seok;Shin, Seung-Soo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.10a
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    • pp.104-106
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    • 2022
  • Single-person households are steadily increasing every year, and unlike multi-person households, the incidence of depression is higher because they are mentally isolated. There are many causes of depression, including physical activity, family size, and stress. Less physical activity and more stress are associated with higher rates of depression. As the number of single-person households increased, and the COVID-19 outbreak in 2019 caused restrictions on physical activity due to the overlapping pandemic, the stress index increased, resulting in many depressed patients. Since many patients do not receive treatment even if they develop depression, we propose a depression management system to increase access to treatment for depression.

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Motivations for Healthy Eating Decreased after the COVID-19 Pandemic in the Daqing Area of China

  • Xiaoyu Ma;Seungwoo Lee;Ji-Yun Hwang
    • Journal of the Korean Society of Food Culture
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    • v.39 no.2
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    • pp.106-118
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    • 2024
  • This study examined whether the perceptions of the theory of planned behavior (TPB) and individual and environmental factors related to healthy eating changed after the COVID-19 pandemic among adults living in Daqing, China. Data were collected through two rounds of online surveys conducted from April to May 2021 and from March to April 2023, using a questionnaire previously validated for use in Daqing. Using the snowball sampling method, 571 adult participants were recruited, most of whom were Daqing oilfield workers or members of their families. Multiple linear regression analyses were used to determine if the differences in the perceptions of the TPB and dietary environments exist during and after the pandemic after controlling for potential confounders. Scores of several subcomponents of TPB and mean scores of longterm intentions increased but scores of subcomponents and overall mean of motivation decreased after the outbreak. Multiple linear regression showed that only motivation for healthy eating decreased after the pandemic. Influenced by the pandemic, people increased their healthy eating behaviors. Nevertheless, as the pandemic subsided and the pace of life accelerated, people tended to choose convenient foods over healthy options. Consequently, the motivation for healthy eating has declined post-pandemic compared to during the pandemic.

The effects of stress perception due to COVID-19 and category coherence on category-based inductive generalization (코로나-19로 인한 스트레스 지각과 범주 응집성이 범주기반 귀납적 일반화에 미치는 효과)

  • Lee, Guk-Hee;Doh, Eun Yeong
    • Korean Journal of Cognitive Science
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    • v.33 no.3
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    • pp.135-154
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    • 2022
  • The purpose of this study was to confirm that the property generalization to social categories with low coherence is stronger when stress due to COVID-19 is perceived as high, compared to when stress is perceived as low. To this end, this study selected categories with high coherence(nun, soldier, flight attendant) and categories with low coherence(wedding planner, interpreter, florist), and recruited 336 participants to perform a category-based inductive generalization task(inferring how many properties repeatedly observed by some category members would appear across all category members), and measured their perceived COVID-19 stress. As a result, this study showed that when the cohesion of social categories is high, the effect of property generalization is stronger than when it is low, and the effect of property generalization is stronger in those who perceive stress due to Corona 19 higher than those who perceive it as low. In addition, this study confirmed that people who perceive COVID-19 stress strongly tend to generalize strongly to properties that are repeatedly observed in the low coherence category. This study is important in that it shows that there is a cognitive mechanism that is at the root of the phenomenon that stereotypes and prejudices deepen and discriminatory behaviors increase after the outbreak of COVID-19, such as COVID-19 stress and the resulting increase in attribute generalization tendency.