• 제목/요약/키워드: CORD-2

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후두외상으로 발생한 일측 성대 마비의 감별진단으로서 후두근전도검사의 유용성 -증례보고- (The Clinical Usefulness of Laryngeal Electromyography(LEMG) for Differential Diagnosis of Traumatic Unilateral Vocal Cord Palsy -A Case Report-)

  • 최홍식;김한수;김정홍;장정현
    • 대한후두음성언어의학회지
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    • 제13권2호
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    • pp.188-192
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    • 2002
  • Unilateral vocal cord palsy which is associated with laryngeal trauma is not uncommon event. In a 42-year-old male, a cricoid cartilage fracure had been developed after blunt trauma. The endoscopic findings showed contusion and diffuse swelling around the left arytenoid and false cord. During phonation, the mobility of left side true vocal cord was decreased. There were no level difference and displacement of the left side arytenoid. We used the laryngeal electromyography (LEMG) to make a differential diagnosis between the cricoarytenoid joint dislocation and the injury of recurrent laryngeal nerve. At the right thyroarytenoid muscle and cricothyroid muscle, the findings of LEMG were normal. But the amplitude and frequency during phonation were decreased (partial denervation) at the left thyroarytenoid muscle. LEMG is a very useful method to predict the diagnosis of vocal cord palsy.

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시험관내 배양된 제대혈 모세포에서의 신경항원 발현 (Neural Antigen Expressions in Cultured Human Umbilical Cord Blood Stem Cells in vitro)

  • 하윤;윤도흠;연동수;김현옥;이진주;조용은;최중언
    • Journal of Korean Neurosurgical Society
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    • 제30권8호
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    • pp.963-969
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    • 2001
  • Objectives : Cord blood stem cells have been widely used as donor cells for bone marrow transplantation recently. These cells can give rise to a variety of hematopoietic lineages to repopulate the blood. Recent observations reveal that some bone marrow cells and bone marrow stromal cells(MSCs) can grow to become either neurons or glial cells. It is, however, unclear whether or not there exists stems cells which can differentiate into neurons in the blood during the early stages of postnatal life. Methods : Human cord blood stem cells were prepared from human placenta after full term delivery. To induce neuronal differentiation of stem cells, ${\beta}$-mercaptoethanol was treated. To confirm the neuro-glial characteristics of differentiated stem cells, immunocytochemical stain for NeuN, neurofilament, glial fibrillary acidic protein(GFAP), microtubule associated protein2(MAP2) was performed. RT-PCR was performed for detecting nestin mRNA and MAP2 mRNA. Results : We showed in this experiment that neuro-glial markers(NeuN, neurofilament, MAP2, GFAP) were expressed and axon-like cytoplasmic processes are elaborated in the cultured human cord blood stem cells prepared from new born placenta after full term delivery. Nestin mRNA was also detected in fresh cord blood monocytes. Conclusions : These results suggest that human cord blood derived stem cells may be potential sources of neurons in early postnatal life.

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유산소운동이 척수손상 흰쥐의 전해질 농도에 미치는 영향 (The Effects of Aerobic Exercise on Electrolytes Concentration after Spinal Cord Injured Rats)

  • 하미숙;박래준
    • 대한물리의학회지
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    • 제4권4호
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    • pp.215-220
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    • 2009
  • Purpose:This study was to analyze the electrolyte such as blood Na+, K+, Ca2+ of aerobic exercise on spinal cord injured rats. Methods:SCI model rats were damaged in L1-L2 injected with 6-hydroxydopamine(6-OHDA). For this study went on classifying the control group without aerobic exercise, experimental group with aerobic exercise. Experimental groups were applied as swimming for 15minutes. Results:The results of this study were follows. 1) The body weight of the experimental group increased significantly after aerobic exercise(p<.05). 2) In the case of sodium(has been decreased significantly after 2 weeks(p<.05). 3) In the case of potassium has been increased significantly after 2 weeks(p<.05). 4) In the case of calcium has been increased significantly after 2 weeks(p<.05). Conclusion:Aerobic exercise were positive effect in body weight and electrolyte of the spinal cord injury. Continued swimming exercise can be recommended as an effective intervention for the spinal cord injury.

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Tire 및 Tube의 품질보강(品質補强)에 관(關)한 연구(硏究)(제8보(第8報)) 합성(合成)고무를 다량혼용(多量混用)한 Tire 및 Tube의 시제(試製) (Studies on the Quality Reinforcement for Pneumatic Tire and Tube (Part 8) Physical properties of the experimental production of tire for SBR high contained)

  • 김준수;이명환;염홍찬;이진범;박창호;홍종명;임동호;이해용
    • Elastomers and Composites
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    • 제5권2호
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    • pp.188-194
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    • 1970
  • We have studied to apply of a quantity of SBR contained high and domestic tire cord on manufacture tire. The Physical test of compounds and products, the travelling test of manufactured tires last year had revealed a good results. 1. The physical properties indicated better values than those found in the requirments of military specification. 2. Adhesion of carcass ply cord showed a good results. 3. The physical properties between 1260 d/2 nylon cord and 840d/2 nylon cord of domestic products be showed similar values and its have a results by 2-3 times than standards.

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The changes of nociception and the signal molecules expression in the dorsal root ganglia and the spinal cord after cold water swimming stress in mice

  • Feng, Jing-Hui;Sim, Su-Min;Park, Jung-Seok;Hong, Jae-Seung;Suh, Hong-Won
    • The Korean Journal of Physiology and Pharmacology
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    • 제25권3호
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    • pp.207-216
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    • 2021
  • Several studies have previously reported that exposure to stress provokes behavioral changes, including antinociception, in rodents. In the present study, we studied the effect of acute cold-water (4℃) swimming stress (CWSS) on nociception and the possible changes in several signal molecules in male ICR mice. Here, we show that 3 min of CWSS was sufficient to produce antinociception in tail-flick, hot-plate, von-Frey, writhing, and formalin-induced pain models. Significantly, CWSS strongly reduced nociceptive behavior in the first phase, but not in the second phase, of the formalin-induced pain model. We further examined some signal molecules' expressions in the dorsal root ganglia (DRG) and spinal cord to delineate the possible molecular mechanism involved in the antinociceptive effect under CWSS. CWSS reduced p-ERK, p-AMPKα1, p-AMPKα2, p-Tyk2, and p-STAT3 expression both in the spinal cord and DRG. However, the phosphorylation of mTOR was activated after CWSS in the spinal cord and DRG. Moreover, p-JNK and p-CREB activation were significantly increased by CWSS in the spinal cord, whereas CWSS alleviated JNK and CREB phosphorylation levels in DRG. Our results suggest that the antinociception induced by CWSS may be mediated by several molecules, such as ERK, JNK, CREB, AMPKα1, AMPKα2, mTOR, Tyk2, and STAT3 located in the spinal cord and DRG.

제대혈 Adiponectin과 IGF-I이 태아성장에 미치는 영향 (Correlation of Cord Serum Adiponectin and IGF-I with Fetal Growth in Healthy Term Neonates)

  • 김지영;조수진;김혜순;박혜숙;박은애
    • Neonatal Medicine
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    • 제15권1호
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    • pp.38-43
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    • 2008
  • 목 적 : 태아 시기의 성장이 출생 이후 성인기에 이르기까지 대사 질환 및 심혈관 질환, 제2형 당뇨병 등의 발현에 영향을 미친다는 보고들이 있어왔다. 이에, 정상 체중 만삭아의 제대혈 내 APN 과 IGF-I 농도와 태아 성장 간의 관계에 대해서 알아보고자 하였다. 방 법 : 2003년 10월부터 2005년 3월 사이에 이대목동병원에서 출생한 정상 체중 만삭아 72명을 대상으로 하였다. 대상아들의 제대혈 내 APN과 IGF-I 농도를 ELISA 방법을 이용하여 측정하였고 측정치와 출생체중, 신장, 머리둘레, 성별, ponderal index, 태반 무게, 태아-태반 무게 비, 산모의 임신 중 체중 증가, 산모의 임신 전 BMI와의 관계를 분석하였다. 결 과: 제대혈 평균 APN 농도는 29.2${\pm}$10.46 $\mu$g/mL 였으며, 제대혈 APN 농도와 체중의 관계는 체중이 증가할수록 APN 농도가 증가하다가 일정 체중에 도달한 이후에는 APN이 감소하는 종모양의 관계를 보였다. 제대혈 APN 농도는 여아에서 남아 보다 높았으며(P=0.001), 제대혈 APN 농도와 산모의 BMI는 유의한 음의 상관관계를 보였다(r=-0.301, P=0.027). 평균제대혈 IGF-I 농도는 51.26${\pm}$21.54 ng/mL 였다. 제대혈 IGF-I 농도는 출생체중과 양의 상관관계를 보였다(r=0.312, P=0.009). 결 론: 건강한 만삭아에서 제대혈 APN 농도는 출생 체중에 따라 증가하다가 일정 체중에서부터 감소하는 패턴의 종모양의 관계를 보였다. IGF-I 은 태아 성장, 특히 출생체중과 밀접한 관계가 있었다.

양측 성대마비 환자에 대한 $CO_2$레이저 피열연골 내측부분절제술 (Medial Partial Arytenoidectomy by $CO_2$laser for Bilateral Vocal Cord Paralysis)

  • 최홍식;최영준;이용훈;박헌이
    • 대한기관식도과학회지
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    • 제4권2호
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    • pp.219-224
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    • 1998
  • Bilateral vocal cord paralysis can result in severe airway compromise. Over the years a variety of arytenoidectomy procedures have bee described, and one or more of these have been the gold standard for many years. A widely accepted treatment is endoscopic laser total arytenoidectomy. However, vocal results are usually poor. Objective : To evaluate the effect of treatment of endoscopic laser medial partial arytenoidectorny for bilateral vocal cord paralysis Material and Methods : We performed endoscopic medial partial arytenoidceomy with $CO_2$laser for 3 patients with bilateral vocal cord paralysis. The $CO_2$laser is operated with a continuous 7-watt beam in superpulse mode. We compared degree of dyspnea and glottic area of pre-operation with those of post-operation for 3 patients. We analysed aerodynamic study pre-operatively and post-operatively for 1 patient. Results The symptom of dyspnea was improved markedly and the glottic area was widened from 34% to 50% compared with that of pre-operation. The voice quality was slightly decreased. Tracheotomy was not necessary for not-tracheotomized patient and decanulation was possible for tracheotomized patient post-operatively. Cunclusion: The endoscopic laser medial partial arytenoidectomy is a convient and effective method for opening the posterior glottic airway.

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척수의 혈관성 질환으로 인한 하지마비 환자에 대한 한방치료 치험 2례 보고 (Case Report on the 2 Cases of Patients with Vascular Disease of Spinal Cord)

  • 이용은;김재수;이윤규;임성철;이현종
    • Journal of Acupuncture Research
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    • 제30권3호
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    • pp.141-153
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    • 2013
  • Objectives : The study aimed to show the clinical effects of oriental medical treatments for vascular disease of spinal cord. Methods : The patients were treated using acupuncture, electroacupuncture, pharmacoacupuncture, herbal medication. And the effects for vascular disease of spinal cord have measured in ASIA scale, SCIM III. Results : Sensory score on the ASIA scale is increased 128 to 156 in case 1, 189 to 196 in case 2. Motor score on the ASIA scale isn't changed in case 1, but is increased 90 to 99 in case 2. SCIM III is improved 25 to 30 in case 2. Conclusions : From the above results, It is considered that oriental medical treatments is effective on vascular disease of spinal cord.

Applicability of the Krško nuclear power plant core Monte Carlo model for the determination of the neutron source term

  • Goricanec, Tanja;Stancar, Ziga;Kotnik, Domen;Snoj, Luka;Kromar, Marjan
    • Nuclear Engineering and Technology
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    • 제53권11호
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    • pp.3528-3542
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    • 2021
  • A detailed geometrical model of a Krško reactor core was developed using a Monte Carlo neutron transport code MCNP. The main goal of developing an MCNP core model is for it to be used in future research focused on ex-core calculations. A script called McCord was developed to generate MCNP input for an arbitrary fuel cycle configuration from the diffusion based core design package CORD-2, taking advantage of already available material and temperature data obtained in the nuclear core design process. The core model was used to calculate 3D power density profile inside the core. The applicability of the calculated power density distributions was tested by comparison to the CORD-2 calculations, which is regularly used for the nuclear core design calculation verification of the Krško core. For the hot zero power and hot full power states differences between MCNP and CORD-2 in the radial power density profile were <3%. When studying axial power density profiles the differences in axial offset were less than 2.3% for hot full power condition. To further confirm the applicability of the developed model, the measurements with in-core neutron detectors were compared to the calculations, where differences of 5% were observed.

척수손상인의 적응과정에 관한 근거이론적 접근 (A Ground Theory Approach to the Adaptation Process of the Spinal Cord Injured Persons)

  • 송충숙
    • 동서간호학연구지
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    • 제22권2호
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    • pp.158-169
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    • 2016
  • Purpose: This study is a qualitative research on the adaptation of the spinal cord injury after fortuitous the accident. Methods: The subjects are fifteen spinal cord injuries. As a study method, this author employed Grounded theory, one of the qualitative research methods. For data analysis, the procedures of Grounded theory methodology was adopted, and then the data collection were collected for six months from March to September 2009. Concerning the frequence of interviewing, each participants went through individual interviewing twice at least and up to four times if necessary. Results: As a result of open coding, total thirty six concepts and twenty categories were drawn. To synthesize these categories, they came to choose 'Going into the new self-made spinal cord injury' as a nuclear category. Typological analysis based on the result of the paradigm model divided them into a reality-avoiding, passive coping, reality-maintaining, reality-overcoming, and self-fulfillment type. Conclusion: As a result of this study, family support to those with spinal cord disability is an important factor for their motive for rehabilitation and adjustment, spinal disabilities were accepted to mostly the disabilities in relations with colleagues. Thus it is necessary to give them a nursing intervention through disability group for successful adjustment to life with disability.