• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 1994.05a
• /
• pp.1-4
• /
• 1994

In this study. the microwave dielectric properties, such at dielectric constant(${\varepsilon}_{\gamma}$), unloaded quality factor multiplied with resonant frequency($Q_{u}$.f), and temperature coefficient of resonant frequency(${\tau}_{f}$), were investigated for the low-temperature sintered (Pb, Ca)$ZrO_3$ with $V_2O_{5}$ additives as well as structural properties. As a result, (Pb,Ca)ZrO$_3$ with 0.2 wt% $V_2O_{5}$ additive, sintered at $1200^{\circ}C$, showed good properties like ${\varepsilon}_{\gamma}$ 109, $Q_{u}$.f 2736 GHz, and ${\tau}_{f}$ -2.94 ppm/$^{\circ}C$. Especially ${\tau}_{f}$ was much better than ($Pb_{0.63}Ca_{0.37}$)$ZrO_3$ of which ${\tau}_{f}$ was known to be + 13.4 ppm/$^{\circ}C$, so it seems to be applicated in micorowave device components.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.47 no.3
• /
• pp.265-271
• /
• 2021

Nanoparticles are substances that are smaller in size and smaller than cells that make up the skin. Therefore, they are very suitable as mediators for transmitting drugs or genes across cell membranes, and also deliver specific ingredients into the skin.In this study, nanoparticles were extracted from mugwort and particles of around 100 nm were obtained through dynamic light scattering (DLS), and the results of concentration-dependent enhancement of cell viability in fibroblasts were obtained through MTT assay. In addition, it was confirmed that the COL1A1 mRNA expression level was increased and the IL-6 mRNA expression level was decreased through the quantitative real-time PCR analysis method. Moreover, as these nanoparticles were confirmed to be stable, they can be applied not only to cell experiments but also to cosmetic formulations. While the demand for plant-derived ingredients continues to increase, excluding chemical ingredients from the recent cosmetics industry trend, there is a limitation in that there are few research results suggesting the application field of plant-derived nanoparticles. Therefore, in order to overcome the limitations of the cosmetic industry at the present time, the results obtained in this study present nanoparticles derived from Artemisia princeps (NDAP) as a highly functional cosmetic material.

• Nutrition Research and Practice
• /
• v.11 no.3
• /
• pp.190-197
• /
• 2017

BACKGROUND/OBJECTIVES: Gallus gallus domesticus (GD) is a natural mutant breed of chicken in Korea with an atypical characterization of melanin in its tissue. This study investigated the effects of melanin extracts of GD on osteoblast differentiation and inhibition of osteoclast formation. MATERIALS/METHODS: The effects of the melanin extract of GD on human osteoblast MG-63 cell differentiation were examined by evaluating cell viability, osteoblast differentiation, and expression of osteoblast-specific transcription factors such as bone morphogenetic protein 2 (BMP-2), small mothers against decapentaplegic homologs 5 (SMAD5), runt-related transcription factor 2 (RUNX2), osteocalcin and type 1 collagen (COL-1) by reverse transcription-polymerase chain reaction and western blotting analysis. We investigated the inhibitory effect of melanin on the osteoclasts formation through tartrate-resistant acid phosphatase (TRAP) activity and TRAP stains in Raw 264.7 cell. RESULTS: The melanin extract of GD was not cytotoxic to MG-63 cells at concentrations of $50-250{\mu}g/mL$. Alkaline phosphatase (ALP) activity and bone mineralization of melanin extract-treated cells increased in a dose-dependent manner from 50 to $250{\mu}g/mL$ and were 149% and 129% at $250{\mu}g/mL$ concentration, respectively (P < 0.05). The levels of BMP-2, osteocalcin, and COL-1 gene expression were significantly upregulated by 1.72-, 4.44-, and 2.12-fold in melanin-treated cells than in the control cells (P < 0.05). The levels of RUNX2 and SMAD5 proteins were higher in melanin-treated cells than in control vehicle-treated cells. The melanin extract attenuated the formation of receptor activator of nuclear factor kappa-B ligand-induced TRAP-positive multinucleated RAW 264.7 cells by 22%, and was 77% cytotoxic to RAW 264.7 macrophages at a concentration of $500{\mu}g/mL$. CONCLUSIONS: This study provides evidence that the melanin extract promoted osteoblast differentiation by activating BMP/SMADs/RUNX2 signaling and regulating transcription of osteogenic genes such as ALP, type I collagen, and osteocalcin. These results suggest that the effective osteoblastic differentiation induced by melanin extract from GD makes it potentially useful in maintaining bone health.

• KSBB Journal
• /
• v.31 no.2
• /
• pp.126-134
• /
• 2016

To examine the possibility of using Musa sapientum L. (Banana) leaf extract as a cosmetic raw material, banana leaves grown in Jeju Island were extracted with 70% ethanol. Polysaccharides present in banana leaf extract were discarded by precipitation with cold ethanol. Polysaccharide-discarded banana leaf extract promoted procollagen and COL1A1 gene expression, but inhibited matrix metalloproteinase (MMP)-1 and MMP-2 gene expression in human skin fibroblasts when examined by real-time reverse-transcription polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA). The active compound in banana leaves was identified by fractionation with various solvents. The chloroform fraction showed the highest anti-wrinkle efficacy and the active compound of chloroform fraction was identified as corosolic acid by NMR, FT-IR, EA, and HPLC-MS. In addition, banana leaf extract showed anti-oxidative efficacy with an IC50 value of 67.91 ppm, as determined by DPPH free radical scavenging assay. Finally, the anti-wrinkle efficacy of banana leaf extract-containing cream was confirmed by clinical tests. Based on these results, banana leaves could have an application as a cosmetic raw material with anti-wrinkle efficacy.

• The Journal of Natural Sciences
• /
• v.8 no.1
• /
• pp.41-45
• /
• 1995

A. partially decationized Y zeolite was pretreated under specific conditions. It was found this calcinated zeolite retains its separation properties for mixtures of the gases hydrogen, nitrogen, oxygen, carbon monoxide, and methane but has much lower affinity for water molecules than untreated, e.g., zeolites A type or X type. The observed effect is discussed on the basis of the results of adsorption measurements on the adsorption capacities, isotherms, and heats of adsorption.

• Journal of Ship and Ocean Technology
• /
• v.3 no.1
• /
• pp.12-26
• /
• 1999

A new concept of collision energy absorbing system for ;he New Oil-tankers with Advanced Double Hull Structure(NOAHS and NOAHS II) are presented through the joint-research pro-gran between Inha and Hamburg-Harburg University. A comparative study on col vision resistance of these proposed side structures with standard double hull structure of 310K DWT class VLCC, is carried out. The fatigue investigation of structural detail parts is also included. It contains a comparative fatigue study based on pertinent regulations of Classification Societies.

• Journal of Korean Society for Quality Management
• /
• v.20 no.1
• /
• pp.158-167
• /
• 1992

This paper represents the new techniques for optimal sampling plans of reliability applying the mathematical complex number(real and imaginary number) in the complex system of reliability. The research formulation represent a mathematical model Which preserves all essential aspects of the main and auxiliary factors of the research objectives. It is important to formule the problem in good agreement with the objective of the research considering the main and auxilary factors which affect the system performance. This model was repeatedly tested to determine the required statistical chatacteristics which in themselves determine the actual and standard distributions. The evaluation programs and techniques are developed for establishing criteria for sampling plans of reliability effectiveness, and the evaluation of system performance was based on the complex stochastic process(derived by the Runge-Kutta method. by kolmogorv's criterion and the transform of a solution to a Sturon-Liouville equation.) The special structure of this mathematical model is exploited to develop the optimal sampling plans of reliability in the complex system.

• The Journal of Natural Sciences
• /
• v.5 no.2
• /
• pp.63-73
• /
• 1992

There are many methods of obtaining butadiene described in the literature. In the america it is produced largely from petroleum gases, i.e., by catalytic dehydrogenation of butene of butene-butane mixtures. Butadiene can be recovered from the $C_4$ residue of an olefin plant by distilling off a fraction containing most of the butadiene, catalytically hydrogenating the higher acetylenes to olefins and separating the product from other olefins and isobutane by extraction. Also it can be obtained by cracking naphtha and light oil. Among the individual dienes of commercial importance, 1, 3-butadiene is of first importance. It is used primarily for the production of polymers.In the present paper, it was investigated for a effect of the formation and the growth inhibition of popped corn polymer in butadiene extraction unit. As a result of study, inhibitors, $NaNO_2$ and TBC were good effective for inhibition of the formation and growth in popcorn polymer. The rational formula of popcorn polymer obtained was $(C_4H_6)_x$.

• Journal of Power Electronics
• /
• v.2 no.1
• /
• pp.67-75
• /
• 2002

This paper presents the control algorithm for maximum efficiency drives of an induction motor system with the high dynamic performance. This system uses a simple model of the induction motor that includes equations of the iron losses. The model, which only requires the parameters of the induction motor, is referred to a field-oriented frame. The minimum point of the input power can be obtained at the steady state condition. The proposed optimal efficiency control algorithm calculates the reference torque and flux currents for the vector control of the induction motors. A 32 bit floating point TMS320C32 DSP chip implements the drive system with the efficiency optimization controller. The results show the effectiveness of the control strategy Proposed for the induction motor drive.

• Magazine of the Korea Concrete Institute
• /
• v.7 no.1
• /
• pp.156-164
• /
• 1995

P-${\Delta}$ analysis by use of the equivalent colurnn stiffness determined by Momcnt curvature-Thrust curves provides relatively precise analytical results for unbraced reinforced concrete columns, however it needs a complicated arialytical procedure. Equ~valent col~rnn stiffness equations are proposed for a simple analytical procedure which are ckterrnined by the Moment-Curvature Thrust curves of the practically useable sections. Thc proposed stiffness equations are appiled to P-${\Delta}$ analysis and rnornent magnifier method to compare with the selected test result. Use of the proposed stiffness equations may slrnplify the P-${\Delta}$ i.rialvtica1 procedure and improve the accuracy of moment magnifier niethod.