• Title/Summary/Keyword: CO(carboxy)-Hb

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Toxicity Evaluation of Effluent Gases from a Residental Fire by Rats (연립 주택 화재시 유독가스 방출 특성과 Rats를 이용한 독성평가)

  • Kim, Hong;Kang, Young-Goo;Kim, Dong-Hyun;Jung, Ki-Chang;Lee, Chang-Seop;Kim, Woon-Hyung
    • Fire Science and Engineering
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    • v.16 no.3
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    • pp.12-15
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    • 2002
  • It has long been recognized that exposure to fire-induced toxic gases is a fatal hazard confront-ing people in fires. In this study, an indoor fire experiment was conducted in an unoccupied residential building located in An-san city, Kyoung-gi province, and the composition of effluent gases, which include CO, $CO_2$, $O_2$, $SO_2$, NO and $NO_2$, were measured by a gas analyzer. A group of lab rats were exposed to the toxic gases released from fire, and the blood samples of the rats were gathered every 2 minutes. A toxicity evaluation was conducted by analyzing the concentrations of Glucose, AST(GOT), ALT(GPT), CBC Count and CO(carboxy)-Hb in the blood samples. Shown from the analysis is the does-response relationship between the CO concentration that rats were exposed to and the CO-Hb concentration in rat blood.

A Comparison of Gases and Heavy Metals in Blood between Urban and Rural Teenager (도시(都市)와 농촌(農村) 약년자(若年者)의 혈액(血液)가스 및 중금속(重金屬) 함량(含量) 비교(比較))

  • Lee, Sang-Sook;Kim, Doo-Hie
    • Journal of Preventive Medicine and Public Health
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    • v.18 no.1
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    • pp.129-136
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    • 1985
  • This paper is carried out to determine the venous blood gas components and heavy metals, such as lead, cadmium and copper, in blood between urban and rural teenager. The subjects were 34 in urban, Taegu city and 37 in rural, Euisung-Gun. But smokers were excluded. The specimens were sampled in May, 1985. The heavy metals were analyzed by atomic absorption spectrophotometry (IL. 551) and carboxy-Hb, Met-Hb, Hb, $O_2\;and\;CO_2$, blood gas analyzer (IL. 1301) and CO-oximeter (IL. 282). In urban group, $PO_2\;and\;O_2-Hb$ were significantly lower than in rural (p<0.01, p<0.03, respectively), and ${HCO_3}^{-}\;and\;TCO_2$ were significantly higher than in rural (p<0.01, p<0.01, respectively). CO-Hb concentration was rather higher in the rural group than the urban (p<0.03), other Met-Hb was higher in urban group than in the rural (p<0.01). Lead and cadmium were also significantly higher in the urban group (p<0.03, p<0.02, respectively).

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