• Magazine of the Korean Society of Agricultural Engineers
• /
• v.43 no.2
• /
• pp.132-139
• /
• 2001

This study deals with coal-mine waste (CMW) for use in concrete as a replacement of normal aggregates. The CMW was collected from Sabuk region. Ganwon-do. Fine and coarse aggregates from CMW were prepared by using a crusher and separating debris with #4 sieve. CMW aggregates showed good physical and mechanical properties with having specific gravity over 2.65, absorption less than 1%, and abrasion ratio below 20%. However, particle shape of CMW was poor because of non-isotropic nature of matrix which cause particles to be long or flat. Since irregular particles caused a poor workability, to make workability better, a 1/4 of coarse aggregate was replaced with normal aggregate together with a superplasticizer. Compressive strength and other mechanical properties of CMW concrete were very good. Color of the concrete was darker than normal concrete due to black color of CMW. In conclusion, characteristics of CMW concrete was acceptable for use as a structural concrete material.

• Journal of Industrial Technology
• /
• v.16
• /
• pp.105-112
• /
• 1996

This paper presents coal mine waste (CMW) for use in concrete manufacture as a replacement of normal aggregates. The CMW in this study was collected from Sabook, Jungson-kun, Kangwon-do. Fine and coarse asggregates from CMW were prepared by crushing it in a jaw crusher and separating debris with #4 sieve. CMW aggregates showed good physical and mechanical properties with having specific gravity over 2.65, absorption less than 1%, and abration ratio below 20%, but particle shape of CMW was long or flat, which caused a poor workability in mixing. Therefore, to make workability better, a 1/4 of CMW coarse aggregate was replaced with normal aggregate which had a good particle shape, and a superplasticizer was added to the mix. Compressive strength and other mechanical properties of CMW concrete was very good. In conclusion, characteristics of CMW concrete was acceptable for use as a concrete structural material.

• Nutrition Research and Practice
• /
• v.11 no.3
• /
• pp.180-189
• /
• 2017

BACKGROUND/OBJECTIVES: Recent living condition improvements, changes in dietary habits, and reductions in physical activity are contributing to an increase in metabolic syndrome symptoms including diabetes and obesity. Through such societal developments, humankind is continuously exposed to metabolic diseases such as diabetes, and the number of the victims is increasing. This study investigated Cordyceps militaris water extract (CMW)-induced glucose uptake in HepG2 cells and the effect of CMW treatment on glucose metabolism. MATERIALS/METHODS: Colorimetric assay kits were used to determine the glucokinase (GK) and pyruvate dehydrogenase (PDH) activities, glucose uptake, and glycogen content. Either RT-PCR or western blot analysis was performed for quantitation of glucose transporter 2 (GLUT2), hepatocyte nuclear factor 1 alpha ($HNF-1{\alpha}$), phosphatidylinositol 3-kinase (PI3k), protein kinase B (Akt), phosphorylated AMP-activated protein kinase (pAMPK), phosphoenolpyruvate carboxykinase, GK, PDH, and glycogen synthase kinase 3 beta ($GSK-3{\beta}$) expression levels. The ${\alpha}-glucosidase$ inhibitory activities of acarbose and CMW were evaluated by absorbance measurement. RESULTS: CMW induced glucose uptake in HepG2 cells by increasing GLUT2 through $HNF-1{\alpha}$ expression stimulation. Glucose in the cells increased the CMW-induced phosphorylation of AMPK. In turn, glycolysis was stimulated, and glyconeogenesis was inhibited. Furthermore, by studying the mechanism of action of PI3k, Akt, and $GSK-3{\beta}$, and measuring glycogen content, the study confirmed that the glucose was stored in the liver as glycogen. Finally, CMW resulted in a higher level of ${\alpha}-glucosidase$ inhibitory activity than that from acarbose. CONCLUSION: CMW induced the uptake of glucose into HepG2 cells, as well, it induced metabolism of the absorbed glucose. It is concluded that CMW is a candidate or potential use in diabetes prevention and treatment.

• Asian-Australasian Journal of Animal Sciences
• /
• v.12 no.6
• /
• pp.843-845
• /
• 1999

To evaluate direct and maternal effects on calf market weight (CMW) and carcass weight (CW) in Japanese Black cattle under an animal model, genetic parameters were estimated using 51,320 records of CMW and 11,944 records of CW, respectively. Direct and maternal heritabilities, and direct-maternal genetic correlation were estimated to be 0.22, 0.06 and 0.27 for CMW, and 0.23, 0.12 and -0.40 for CW, respectively. Correlation coefficient between maternal breeding values for CMW and CW was 0.521 for 157 sires appeared in both CMW and CW data sets. These results suggest that the maternal genetic effect on pre-weaning growth carries over to carcass weight. Maternal breeding values for both calf market weight and carcass weight could be used as the indicator traits of maternal ability in Japanese Black cattle.

• The Journal of the Korean bone and joint tumor society
• /
• v.7 no.1
• /
• pp.1-12
• /
• 2001

Purpose : To elucidate possibility of local chemotherapy from adraimycin-impregnated bone cement. Materials and Methods : Authors used 4 kinds of bone cements, Palcos R, LVC, CMW 3, Simplex P for this experimental model, included 2.5mg, 5mg, 25mg of adriamycin, respectively. We compared the differences of eluted-adriamycin concentrations between the cylindrical shape and the flat shape of bone cements, between ddH2O, 0.45% saline, 0.9% saline, and 3% saline as one of environmental conditions. Osteosarcoma cell line, Saos-2 were cultured under $37^{\circ}C$, 5% $CO_2$ in the humidified incubator with three different concentrations of adriamycinimpregnated bone cements and cellular toxicity of adriamycin eluted from bone cement was analysed according to MTT assay. Results : Authors noticed the flat shape of bone cement eluted more concentrations of adriamycin than the cyclindrical shape, bone cement immersed in 3% saline, more than 0.9% or 0.45% saline. Concentrations of adriamycin eluted from CMW 3 or Simplex R were more than Palacos R or LVC. Saos-2 were cultured with 2.5mg, 5mg, 25mg of adriamycin-impregnated bone cement, respectively, and their cellular toxicity were 95%, 98%, 99%, each. Conclusion : Adriamycin-impregnated bone cement can be one of anticancer-drug delivery sytems as possible local chemotherapy.

• Transactions of the Korean Society of Mechanical Engineers
• /
• v.14 no.5
• /
• pp.1211-1221
• /
• 1990

The purpose of this study is to get experimental data on the distribution of CWM (Coal- Water Mixture) droplets size and the presence of pulverized coal particles inside CWM droplets. Atomization of CWM is done by Twin-Fluid Atomizer. The operational parameters are atomizing air pressure, coal particle loading, mean size of pulverized coal particles and sampling positions across spray. Th data analysis is initiated by Impression Sampling Method(Magnesium Oxide Technique) and Photo-technique and counting works are followed. Experimental work induces following research results. The variation of particle loadings in slurry makes no appreciable effects on the mean size of CWM droplets. It is evident that atomizing air pressure has very strong effect on the atomization of slurry. The mean size of atomized fuel droplets is dramatically reduced with the increasing air pressure. The population ratio of droplets without coal particles to total number of droplets is decreased as atomizing air pressure or loading rises and the same trend is obtained as the mean size of coal particles becomes smaller but a certain tendency of coal particle presence inside droplets could not be found from the change of sampling positions.