• Title/Summary/Keyword: CD59

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A Development of General Purpose Program NUFLEX for the Analysis of Heat/Fluid Flow (범용 열/유체 유동해석 프로그램 NUFLEX의 개발)

  • Hur N.;Won C.-S.;Son G.;Ryou H.-S.;Shin D.
    • 한국전산유체공학회:학술대회논문집
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    • 2004.10a
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    • pp.53-59
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    • 2004
  • A general purpose program NUFLEX for the analysis of 3-D heat/fluid flow in complex geometry with pre/post processor have been developed, which consists of a flow solver based on FVM and a dedicated pre/post processor. The program employs a general non-orthogonal grid system and solve laminar and turbulent (lows with standard and RNG $\kappa-\epsilon$ turbulence models. NUFLEX is capable of analysing two-phase flow with topologically complex interface, turbulent diffusion combustion, solidification problems and magnetic flow. For the purpose of verification of the program and testing the applicability, several practical problems are solved and compared with the available data. Comparison of the NUFLEX results with that by the STAR-CD program has been also made for the same flow configuration and grid structure.

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Evaluation of the Safety of Fried-Food in Fast Food Store (패스트푸드점 튀김식품의 안전성 평가)

  • 박건용;정보경;김애경;박경애;조성자;곽재은;장민수;배청호;조남준
    • Journal of Food Hygiene and Safety
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    • v.19 no.2
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    • pp.55-59
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    • 2004
  • This study was performed to investigate 172 samples of fried food in fast food store. The free fatty acid value of 22 samples exceeded standard of fried-food. These samples were 10 fried chickens, 6 fried potatoes and 5 fried onions. Fatty acid composition differed from each company. The correlation between free fatty acid value and double bond index was very low. New standard of fried food in fast food store is needed for thorough hygiene management, because of being not existed standard. The fried potato containing many carbohydrate and fat appeared higher calory than fried chicken containing many protein. The fried food had high fat comparatively, so that attention in regard to excess intake is demanded. The trace materials were included Mg, Ca, Mn, Fe, Zn, Cu and Cr in order of quantity, and the harmful heavy metals-Pb, Hg and Cd- were included small quantity.

Functional Analysis of the First Mannosyltransferase (PIG-M) involved in Glycosylphosphatidylinositol Synthesis in Plasmodium falciparum

  • Kim, Youn Uck;Hong, Yeongjin
    • Molecules and Cells
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    • v.24 no.2
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    • pp.294-300
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    • 2007
  • The mammalian glycosylphosphatidylinositol (GPI) anchor consists of three mannoses attached to acylated GlcN-(acyl)PI to form $Man_3$-GlcN-(acyl)PI. The first of the three mannose groups is attached to an intermediate to generate Man-GlcN-(acyl)PI by the first mannosyltransferase (GPI-MT-I). Mammalian and protozoan GPI-MT-I have different substrate specificities. PIG-M encodes the mammalial GPI-MT-I which has 423 amino acids and multiple transmembrane domains. In this work we cloned PIG-M homologues from humans, Plasmodium falciparum (PfPIG-M), and Saccharomyces cerevisiae (GPI14), to test whether they could complement GPI-MT-I-deficient mammalian cells, since this biosynthetic step is likely to be a good target for selective screening of inhibitors against many pathogenic organisms. PfPIG-M partially restored cell surface expression of the GPI-anchored protein CD59 in PIG-M deficient mammalian cells, and first mannose transfer activity in vitro; however, this was not the case for GPI14.

Ecological support system for promoting youth culture in a new millenium age A study of Adolescents consumer conspicuous consumption - Comparisons between seoul city, small and medium-sized cities and towns - (새 밀레니엄에서의 청소년 문화창조를 위한 생태학적 지원체계(III): 청소년의 건전소비문화 정착을 위한 과시소비 기초 분석 -서울시, 중소도시, 군.읍.면 비교-)

  • 계선자;이정우;김명자;박미석;강기정
    • Journal of the Korean Home Economics Association
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    • v.38 no.12
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    • pp.15-28
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    • 2000
  • The purpose of this study is to analyze Adolescents spending habits and examine it. The data was collected from 1125 high school students and their parents nationwide. The resets are as follows. 1. About seventy eight percent of the responded students own relatively high-priced goods such as brand-name jeans (59.1%), a mobile phone (31.9%), perfume with a price of 50,000 won or more (26.5%), CD Player (24.4%) or electronic pocket diary (17.1%). The percentage varies according to region. 2. The Adolescents tendency for conspicuous consumption is reflected by 2.92 points out of a total 5 points, while their mothers'marks 2.18 points. By region, conspicuous consumption behavior is more common in Seoul than in other small and medium-sized cities and towns. Also, the more mother attribute children's behavior internally, the lower the childeren's competence is.

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A Study on the Effects of Radix Menispermi Extracts Against Cadmium Chloride Sub-chronic Toxicity in Rats (카드뮴 중독에 대한 산두근 추출액의 해독효과에 관한 연구)

  • 이종섭;박경옥;이정미
    • Toxicological Research
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    • v.12 no.1
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    • pp.59-68
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    • 1996
  • This study was conducted to investigate the antitoxic effects of Radix Menispermi extracts against cadmium toxicity. The experimental rats were divided into 5 groups such as control group, cadmium alone treatment group and simultaneous treatment groups of cadmium and three doses of Radix Menispermi extracts. Each group was administered with different dose of Radix Menispermi extracts such as 0.55 mg, 1.10 mg, 1.65 mg/kg wet weight in pallets for 12 weeks. Cadmium Chloride $(CdCl_2)$ was administered by 4 mg/kg body weight. The results were summarized as follows: 1. The simultaneous administration of cadmium and Radix Menispermi significantly more decreased cadmium concentration in liver tissues compared to the administration of cadmium only (P < 0.05). 2. When blood were measured, no significantly difference in haemoglobin, haematocrit, erythrocyte values compared to the administration of cadmium only. 3. The simultaneous administration of cadmium and Radix Menispermi more increased metallothionein concentration in liver than the administration of cadmium only (P < 0.05). 4. There were the histopathological slight changes in the liver and kidney tissues of rats.

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ANALYSIS OF CHARGE COLLECTION EFFICIENCY FOR A PLANAR CdZnTe DETECTOR

  • Kim, Kyung-O;Kim, Jong-Kyung;Ha, Jang-Ho;Kim, Soon-Young
    • Nuclear Engineering and Technology
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    • v.41 no.5
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    • pp.723-728
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    • 2009
  • The response property of the CZT detector ($5{\times}5{\times}5\;mm^3$), widely used in photon spectroscopy, was evaluated by considering the charge collection efficiency, which depends on the interaction position of incident radiation, A quantitative analysis of the energy spectra obtained from the CZT detector was also performed to investigate the tail effect at the low energy side of the full energy peak. The collection efficiency of electrons and holes to the two electrodes (i.e., cathode and anode) was calculated from the Hecht equation, and radiation transport analysis was performed by two Monte Carlo codes, Geant4 and MCNPX. The radiation source was assumed to be 59.5 keV gamma rays emitted from a $^{241}Am$ source into the cathode surface of this detector, and the detector was assumed to be biased to 500 V between the two electrodes. Through the comparison of the results between the Geant4 calculation considering the charge collection efficiency and the ideal case from MCNPX, an pronounced difference of 4 keV was found in the full energy peak position. The tail effect at the low energy side of the full energy peak was confirmed to be caused by the collection efficiency of electrons and holes. In more detail, it was shown that the tail height caused by the charge collection efficiency went up to 1000 times the pulse height in the same energy bin at the calculation without considering the charge collection efficiency. It is, therefore, apparent that research considering the charge collection efficiency is necessary in order to properly analyze the characteristics of CZT detectors.

A Study of Heavy Metal Pollutants in the Respirable Dust in Seoul Area (호흡성분진중의 중금속 오염도에 관한 조사연구)

  • Lim, Young-Wook;Chung, Young
    • Journal of Korean Society for Atmospheric Environment
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    • v.5 no.1
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    • pp.68-78
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    • 1989
  • The heavy metal of suspended particulates with human health has long been studied in environmental interest concerned. This study was intended to identify harmful heavy metals of the ambient air borne dusts which were related with the respirable sizes in the aerodynamics. Two sampling sites were selected comparatively; one was in the Shinchon area, which is the commercial district with heavy traffic and the other site was in the Bulgwang area which is residential area. The supended particulates were sampled by high volume air sample with 6 cascade impactor stages. The heavy metals in terms of As, Cd, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se, V and Zn were determined by stomic absorption spectrometry or inductively coupled plasma emission spectrometry. The samples weretaken bimothly for seven consecutive days from May 1987 to March 1988. The annual average concentration of the respirable suspended dust of which diameter is less than 10$\mum$ was 152.59 $\mug/m^3$ of the Shinchon air samples; the respirable dust was equivalent to approximately 85% of the total suspended particulates. The annual average concentration of the respirable suspended dust of the Bulgwang air samples was 112.56 $\mug/m^3$; that was approximately 86% of the total suspended particulates. The concentration of heavy metals was investigated in relation to the particle size. The concentration of Cr, Fe, Mn and V were tended to be much more in the coarse particles than in the fine particles. Cd and Pb in the fine particles were more than in the coarse particles. In the partial correlation coefficients; in the Shinchon area, high correlations among Fe, Se and Mn were determined; it is assumed that those sources would be originated from coal, gasolineand diesel. In Bulgwang area, would be high correlation among Fe, Se, Hg and Mn considered to be originated from coal, Bunker-C and heavy oil as well. From the above results, the hazardous heavy merals in air should be measured and controlled in originally their sources.

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Heavy Metal Contamination in Surface Water Used for Irrigation: Functional Assessment of the Turag River in Bangladesh

  • Arefin, M. Taufique;Rahman, M. Mokhlesur;Wahid-U-Zzaman, M.;Kim, Jang-Eok
    • Journal of Applied Biological Chemistry
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    • v.59 no.1
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    • pp.83-90
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    • 2016
  • The aim of the present study was to evaluate the degree of metal contamination of the Turag River water and its suitability for irrigation. Twenty water samples were analyzed for physicochemical parameters and metals viz., calcium, magnesium, potassium (K), sodium, copper (Cu), zinc (Zn), iron (Fe), manganese (Mn), lead (Pb), cadmium (Cd), chromium (Cr), and nickel (Ni). All water samples were slightly alkaline to alkaline. Regarding electrical conductivity (EC), all samples were suitable for crop in soils with moderate permeability and leaching. Water samples were medium salinity and low alkalinity hazard classes. In terms of total dissolved solids (TDS), all samples were classified as freshwater. As per sodium adsorption ratio (SAR) and soluble sodium percentage (SSP), all samples were classified as excellent. No residual sodium carbonate (RSC) was detected in any of the samples, indicating suitability for irrigation; and all samples were considered very hard. Cr and Mn contents in all samples were above FAO guideline values and, therefore, these metals were considered toxic. Zn, Cu, Pb, Cd, and Ni concentrations were below acceptable limit for irrigation and do not pose a threat to soil environment. Significant relationships were found between EC and TDS, SAR and SSP, SAR and RSC, and SSP and RSC. The combinations of ions such as K-Zn, K-Fe, K-Cu, K-Mn, K-Pb, Zn-Fe, Zn-Cu, Zn-Mn, Fe-Mn, Cu-Mn, Cu-Pb and Mn-Pb exhibited significant correlation. This study revealed that Turag River water samples are contaminated with Cr and Mn. This fact should not be ignored because water contamination by metals may pose a threat to human health through food chain.

Development of Multi-functional Ceramics for Removal of Heavy Metals in Acid Wastewater using Industrial By-product (산업부산물을 활용한 산성폐수 내 중금속 제거용 다기능성 세라믹 소재의 개발)

  • Kim, Dong-Hee;Yim, Soo-Bin
    • Journal of Korean Society on Water Environment
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    • v.28 no.2
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    • pp.277-284
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    • 2012
  • This study developed a new ceramics in which natural zeolite was mixed and calcined with industrial by-product such as converter slag, red mud, and fly ash and evaluated the feasibility of the ceramics for removal of heavy metals in acid wastewater. The removal rate of heavy metal by ceramics increased in the order of ZS (zeolite and slag) > ZR (zeolite and red mud) > ZF (zeolite and fly ash) ceramics. The alkalinity increment and coherence of ceramics were increased in the order of ZS > ZR > ZF ceramics. The mixing ratio of natural zeolite to industrial by-product for maximum removal efficiency of heavy metal was 1:1 for ZS ceramics and 1:3 for ZR and ZF ceramics. The order of removal efficiency of heavy metal was observed to be ZS > ZR > ZF ceramics under the mixing ratio of 1:1 for ZS ceramics and 1:3 for ZR and ZF ceramics. The removal efficiency of heavy metal by ZS ceramics with 1:1 mixing ratio was Al 100%, Cd 54.6%, Cr 99.9%, Cu 98.7%, Fe 99.9%, Mn 42.2%, Ni 59.9%, Pb 99.8%, Zn 87.6%, respectively. In addition, the removal capacity of heavy metal by ZS ceramics was observed to be Al 2.01 mM/g, Cd 0.27 mM/g, Cr 1.02 mM/g, Cu 0.83 mM/g, Fe 0.95 mM/g, Mn 0.41 mM/g, Ni 0.55 mM/g, Pb 0.25 mM/g, Zn 0.70 mM/g, respectively. The comparative evaluation in the light of removal capacity, alkalinity increment, and coherence of ceramics showed the ZS ceramics had higher feasibility as a media than others for removal of heavy metals in acid wastewater.

First Outcome of MDR-TB among Co-Infected HIV/TB Patients from South-West Iran

  • Motamedifar, Mohammad;Ebrahim-Saraie, Hadi Sedigh;Abadi, Ali Reza Hassan;Moghadam, Mahboube Nakhzari
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.3
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    • pp.253-257
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    • 2015
  • Background: Tuberculosis (TB) is the leading cause of mortality among human immunodeficiency virus (HIV) patients and the majority of them occur in developing countries. The aims of the present study were to determine the frequency of HIV/TB co-infection and other probable associated factors. Methods: This 10 year retrospective study was conducted on 824 HIV patients in the south-west of Iran. HIV infection was diagnosed by the enzyme linked immunosorbent assay and confirmed by Western blot. TB diagnosis was based on consistency of the clinical manifestations, chest X-ray, and microscopic examination. Drug susceptibility testing was done by the proportional method on $L{\ddot{o}}wenstein$-Jensen media. Results: Of 824 HIV patients, 59 (7.2%) were identified as TB co-infected and the majority (86.4%) of them were male. Of the overall TB infected patients, 6 cases (10.2%) showed multidrug-resistant with the mean CD4+ lymphocyte count of $163{\pm}166cells/mm^3$. The main clinical forms of TB were pulmonary (73%). There was a significant (p<0.05) correlation between TB infection and CD4+ lymphocyte counts ${\leq}200cells/mm^3$, gender, prison history, addiction history, and highly active anti-retroviral therapy. Conclusion: We reported novel information on frequency of HIV/TB co-infection and multidrug resistant-TB outcome among co-infected patients that could facilitate better management of such infections on a global scale.