• Title/Summary/Keyword: CD137

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국내외 CD-ROM 데이터베이스

  • Korea Database Promotion Center
    • Digital Contents
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    • no.4 s.35
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    • pp.132-137
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    • 1996
  • 해외 데이터베이스 문헌정보 소개에 이어 국내외에 산재해 있는 CD-ROM관련 데이터베이스를 수회에 걸쳐 소개하고자 한다. 데이터베이스 관련 CD-ROM 타이틀은 국내에서도 자료가 정리되지 않은 것이 사실이다. 본 센터에서는 데이터베이스 관련 CD-ROM타이틀을 주제별로 정리하였으며 크게는 DB전반(DB의 DB), 일상생활, 경제산업, 학술, 예술기능, 체육 등으로 분류하였으며, 중분류로는 생활상식, 교양,문화 등이며 소분류로는 중분류보다 세세하게 분류를 하였다. 따라서 본고에서는 CD-ROM 데이터베이스 정보와 CD-ROM제작기관 정보를 소개하고자 하며 이번호에서는 CD-ROM 데이터베이스를 게재한다.

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Foliar Transfer of Dust and Heavy Metals on Roadside Plants in a Subtropical Environment

  • Gajbhiye, Triratnesh;Kim, Ki-Hyun;Pandey, Sudhir Kumar;Brown, Richard J.C.
    • Asian Journal of Atmospheric Environment
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    • v.10 no.3
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    • pp.137-145
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    • 2016
  • In this study, the contents of dust and associated heavy metals on roadside plants were investigated to assess their foliar transfer. The study was conducted at six different locations (four roadside and two industrial) near an industrial area in Bilaspur (Chhattisgarh), India. Six metals (Fe, Mn, Pb, Cu, Cr, and Cd) were examined in this study. The concentrations of heavy metals in foliar dust were found to be in the order of Fe>Mn>Pb>Cu>Cr>Cd. However, this relative order changed in the case of leaf concentrations to Fe>Mn>Cd>Cu>Pb>Cr. The metal concentrations in the dust and leaves can be attributed mainly to industrial and vehicular emissions. In contrast to other metals, Cd showed significant accumulation in the leaves compared to the respective dust samples. This study showed different patterns in the distributions of heavy metals between the dust deposited on the leaves and the metal accumulated in the leaves. These results suggest that the dust retention and heavy metal accumulation in native plant species should be explored in an attempt to manage these hazardous metallic elements.

Significance of Expression of CD44s and CD44v6 in Colorectal Cancer

  • Kim, Doo-Jin;Bae, Ok-Suk;Kim, Yong-Hoon;Park, Sung-Dae
    • Biomedical Science Letters
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    • v.8 no.3
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    • pp.137-142
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    • 2002
  • The expression of CD44v is known as a marker of cancer progression and its metastasis in colorectal cancer. It has been known that CD44 variant containing sequences encoded by exon 11 (v6) confer metastatic potential to human colorectal cancer cells. The role of CD44 standard (CD44s) and CD44v6 in colorectal cancer was investigated in this study by immunohistochemical staining of the primary tumors obtained from the colorectal cancer patients. Immunohistochemical staining was performed in 40 patients with colorectal cancer who underwent curative surgery at Keimyung University hospital. The expression CD44s and CD44v6 was observed in 24/40 (60%) and 13/40 (32.5%) respectively. The expression of CD44v6 had correlation with TNM stage (P<0.05), however CD44s had not any correlation with clinicopathological parameters. These results suggest that CD44v6 expression may give an information for tumor progression than decreased expression of CD44s in colorectal cancer cells.

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가교화 $\beta$-Cyclodextrin에 의한 라드의 Cholesterol 제거 최적화와 재활용에 관한 연구

  • Kim, Song-Hui;Kim, Hye-Yeong;Bae, Hyeon-Yeong;An, Jeong-Jwa;Gwak, Hae-Su
    • Proceedings of the Korean Society for Food Science of Animal Resources Conference
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    • 2006.05a
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    • pp.133-137
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    • 2006
  • 본 연구의 목적은 $\beta$-CD를 가교화 시켜 육가공 제품의 주원료인 lard에 내재하는 cholesterol을 효과적으로 제거하기 위한 최적조건 확립이다. 따라서 adipic acid로 가교화한 $\beta$-CD를 이용하여 lard에서 cholesterol을 제거하고 더 높은 효율을 찾기 위하여 실시되었다. 가교화 $\beta$-CD를 이용해 lard에서 cholesterol 제거 실험결과의 최적 조건은 lard:distilled water=1:1, 가교화 $\beta$-CD 5%, 교반온도 $40^{\circ}C$, 교반시간 10분, 교반속도 150rpm으로 실험한 결과 cholesterol 제거율이 평균 92.32%이었다. 또한 10회 재활용 결과 평균 98.04%의 재활용률을 보였으며, 8회 이후에는 유의적으로 감소하여 가교화 $\beta$-CD의 효율적인 재활용이 가능함을 시사하였다. 이 실험의 결과 가교화 $\beta$-CD로 lard의 cholesterol 제거 최적조건을 규명함으로써 콜레스테롤을 저하시킨 육가공 제품의 생산 가능성을 보였다.

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Fabrication of Virtual Frisch-Grid CdZnTe ${\gamma}$-Ray Detector (가상 Frisch-그리드를 이용한 CdZnTe 감마선 소자 제작)

  • Park, Chansun;Kim, Pilsu;Cho, PyongKon;Choi, Jonghak;Kim, Jungmin;Kim, KiHyun
    • Journal of radiological science and technology
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    • v.37 no.4
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    • pp.253-259
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    • 2014
  • Large volume of $6{\times}6{\times}12mm^3$ CdZnTe ${\gamma}$-ray detector was fabricated with CdZnTe single crystals grown by Traveling Heater Method (THM) to evaluate the energy resolution of 662 keV in $^{137}Cs$. Hole tailing effect which originated from the large mobility difference in electron and hole degrade energy resolution of radiation detector and its effects become more severe for a large volume detectors. Generally, single carrier collection technique is very useful method to remove/minimize hole tailing effect and thereby improvement in energy resolution. Virtual Frisch-grid technique is also one of single charge collection method through weighting potential engineering and it is very simple and easily applicable one. In this paper, we characterized CZT detector grown by THM and evaluated the effectiveness of virtual Frisch-grid technique for a high energy gamma-ray detector. The proper position and width of virtual Frisch-grid was determined from electric field simulation using ANSYS Maxwell ver. 14.0. Energy resolution of 2.2% was achieved for the 662 keV ${\gamma}$-peak of $^{137}Cs$ with virtual Frisch-grid CdZnTe detector.

Effect of Dietary Chitin and Chitosan on Cadmium Toxicity and Lipid Metabolism in Rats (Chitin과 Chitosan이 흰쥐의 Cadmium중독과 지방대사에 미치는 영향)

  • 김미경
    • Journal of Nutrition and Health
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    • v.27 no.10
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    • pp.996-1006
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    • 1994
  • This study was performed to investigate the effect of dietary chitin & chitosan on cadmium (Cd) toxicity and lipid metabolism in rats. Forty-two male rats of Sprague-Dawley strain weighing 137$\pm$2g were blocked into 6 groups according to body weight, and were raised for 4 weeks. Cadmium chloride was given at the level of 0 or 400ppm in diet and chitin and chitosan were given at the level of 0 or 4%(w/w) of diet. The results are summarized as follow. Chitosan decreased the toxicity of Cd on liver, kidney and femur and increase the Cd content of fecal excretion. Chitosan increased the lipdi & cholesterol content of fecal excretion by combining with lipid and bile acid. Chitosan decreased lipid, cholesterol and TG content in serum and liver by combining with lipid and bile acid. Chitin was less effective than chitosan in decreasing of Cd toxicity and lipid content of rat.

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Growth and optical properties of undoped and Co-doped CdS single crystals (CdS 및 CdS:Co2+ 단결정의 성장과 광학적 특성)

  • Oh, Gum-kon;Kim, Nam-oh;Kim, Hyung-gon;Hyun, Seung-cheol;Park, hjung;Oh, Seok-kyun
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.51 no.3
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    • pp.137-141
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    • 2002
  • CdS and $CdS:Co^{2+}$ single crystals were grown by CTR method using iodine as transport material. The grown single crystals have defect chalcopyrite structure with direct band gap. The optical energy band gap was decreased according to add of Co-impurity. We can observed the Co-impurity optical absorption peaks assigned to the $Co^{2+}$ ion sited at the $T_d$ symmetry lattice and we consider that they were attributed to the electron transitions between energy levels of ions.

4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy

  • Vinay, Dass S.;Kwon, Byoung S.
    • BMB Reports
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    • v.47 no.3
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    • pp.122-129
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    • 2014
  • Although considerable progress has been made in understanding how tumors evade immune surveillance, measures to counter the same have not kept pace with the advances made in designing effective strategies. 4-1BB (CD137; TNFRS9), an activation-induced costimulatory molecule, is an important regulator of immune responses. Targeting 4-1BB or its natural ligand 4-1BB ligand (4-1BBL) has important implications in many clinical conditions, including cancer. In-depth analysis revealed that 4-1BB-mediated anti-cancer effects are based on its ability to induce activation of cytotoxic T lymphocytes (CTL), and among others, high amounts of IFN-${\gamma}$. In this review, we will discuss the various aspects of 4-1BB-mediated anti-tumor responses, the basis of such responses, and future directions.