• 대한간호학회지
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• 제33권1호
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• pp.60-70
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• 2003

Purpose: The study is designed to develop an educational CD-Program for prevention and control of obesity among primary school students. Method: The study is conducted from June 15, 2000 to April 15, 2002. Based on the course of program development suggested by Dick and Cray (1990), the study followed the planning, development, education and evaluation of a program. Result: The developed CD-Program consists 2 parts each for lower and higher grades of primary school students. The introduction part of the first trial for lower grade students uses quiz to encourage their motivations, the body proceeds with motion pictures and animations to trigger their interests. The introduction part of the second trial for the lower grades consists of remembering the exhibition lecture. The first trial for higher grades of primary school students builds on the contents of the low grades. Its body part, how to determine obesity and calculate ones own obesity, puts ones own weight and height in by the mouse. For the second trial of the higher grades, the body consists of life-style, diet, and regiments. Conclusion: The merits of this CD-Program are that to be possible an interaction between teachers and students.

• 한국간호교육학회지
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• 제17권3호
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• pp.487-500
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• 2011

Purpose: The purpose of this study was to develop a finding meaning in life CD program about life-esteemed education and to identify the effect of the program. Methods: The life-esteemed education philosophy and the concepts of logotherapy were applied as a theoretical framework for this program. This program was developed through the process of planning, designing, developing, and evaluating with a content validity test. To identify the effect of the program, one experimental group design was applied to 54 students. Data were collected before the program started and one week and five weeks after the program finished. Results: The program was developed based on the students' needs and evaluation of the CD's content and consists of five periods: Dinosaur Park of Promise, Hill of Fragrance, Garden of Love, Forest of Acceptance, and My Lake. Each post-test score of knowledge, attitude, and practice on meaning of life was significantly higher than pretest scores. Conclusion: This program can be effective for life-esteemed education in elementary school students. Moreover, it is encouraged that the program will be utilized in more life-esteemed education for elementary school students.

• IMMUNE NETWORK
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• 제7권4호
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• pp.173-178
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• 2007

Background: We studied the role for expression of CD40 and CD40L by CD4 and CD8 T cells in the generation of CD8 T cell response to minor histocompatibility antigen, H60. H60 is a cellular antigen to which CD8 responses require CD4 T cell help. Methods: CD40- or CD40L-deficient mice were adoptively transferred with normal CD4 or CD8 T cells or with memory CD4 or CD8 T cells, and were immunized with male H60 congenic splenocytes to induce CD8 T cell response to H60. Peripheral blood CD8 T cell from the immunized mice were stained with the H60 tetramer. Results: CD8 T cell response to H60 was not induced in both CD40- and CD40L-deficient mice. Adoptive transfer of $CD40^{+/+}$ CD8 T cells into CD40-deficient mice did not compensate the defect in inducing CD8 T cell response to H60, while the H60-specific CD8 T cells were activated in the CD40-deficient mice that were adoptively transferred with $CD40^{+/+}$ CD4 T cells. Adoptive transfer of $CD40L^{+/+}$ CD4 T cells into CD40L-deficient mice induced primary CD8 T cell response for H60 and the presence of $CD40L^{+/+}$ CD4 T cells was required even for memory CD8 T cells response to H60. Conclusion: Our results suggest that the CD40-CD40L interaction mediates the delivery of CD4 T cell help to naive and memory H60-specific CD8 T cells. While the expression of CD40L by CD4 T cells is essential, signaling through CD40 on CD8 T cells is not required for the induction of CD8 T cell response to H60.

• 여성건강간호학회지
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• 제9권4호
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• pp.499-508
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• 2003

Purpose: This study analyzed the effects of a CD- ROM educational program for the prevention of sexual violence in relation to the sexual knowledge of middle school students. Method: A one group, pre-test-post-test design was used. The subjects of this study were 171 middle school students in Kangwon Province, Korea. The questionnaire included 34 items relating to overall sexual knowledge, and included questions on sexual violence. The collected data were analyzed using the mean, standard deviation and paired- t tests. Result: There were significant differences in the sexual knowledge by demographic characteristics between the pre- and post- tests. Of the 34 items, 20 showed significant differences in the sexual knowledge between the pre- and post- tests. Conclus ion: The overall level of sexual knowledge of the students increased after taking the CD- ROM educational program. Further testing will be required to determine the effects of the CD- ROM using a control group and random sampling.

• 보건교육건강증진학회지
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• 제25권3호
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• pp.77-94
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• 2008

Objectives: The purpose of this study was to develop the children obesity prevention program and to analyze how this program has an effect on students' degree of knowledge, attitude for obesity prevention. Methods: The study design was Compromise Experience Group Pre-Post Design. 238 students in the 4th and 5th grade of 4 elementary schools in Seoul were nonrandomly assigned to the study group(n=115) or the control group(n=113). The Program was applied for 3 times and surveys were conducted 2 times as pre-test and post-test. Results: 1. The obesity prevention CD-ROM was developed by analyzing of learners and educational facilities, selecting the study object and contents and producing educational methods and materials. The study contents were included definition, types, factors and side-effects of obesity, and It was contained dietary habit, exercise and life style for obesity prevention and healthy life. 2. Demographic characteristics were not significantly different between study group and control group. Among the subjects investigated, 27.8% of the study group and 38.1% of the control group stated that they had experienced in the obesity prevention program in past. 3. The obesity knowledge and attitude score after this obesity prevention program were improved significantly than before the program(P<0.001). Conclusion: The CD-ROM developed in this study for the children obesity prevention program was proven to be effective in improving obesity knowledge, attitude for the obesity prevention.

• 대한영양사협회학술지
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• 제18권2호
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• pp.115-125
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• 2012

This study was conducted to investigate the effects of food consumption monitoring using a camera-phone in a weight control program. Twenty-six female college students (>30% body fat) were randomly assigned to the camera-phone and diary (CD) group or diary (D) only group. During the 8-week weight control program, the CD group controlled their food consumption using a camera-phone, in which they took a food picture and uploaded it to the homepage. However, the D group used only a diary to record their food intake. The mean energy intake of the CD group during the program was 1451.9 kcal while that of the D group was 1524.3 kcal. The total energy intakes of both groups significantly decreased during the program. The CD group lost 5.2 kg of body weight and 3.1% body fat while the D group lost 2.2 kg of body weight and 1.1% body fat. The body weight and fat levels significantly decreased in the CD group compared to the D group. The triglyceride, total-cholesterol and LDL-cholesterol levels of the CD group as well as the total-cholesterol level of the D group significantly decreased during the program. The total-cholesterol and LDL-cholesterol levels both significantly decreased in the CD group compared to the D group. In this study, it was concluded that digital photography method using a camera-phone might influence weight control through trained consumption monitoring, which helps individuals reduce discrepancies between perceived and actual consumption levels.

• 대한간호학회지
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• 제31권6호
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• pp.1067-1076
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• 2001

This study was to developed to create a CD-ROM and an educational program for the prevention of sexual harassment and violence and to contribute to the perception and add to the coping of the victims of sexual harassment and violence as well as the child, parents, and teachers. Method: The study's methods were literature reviews, surveys, and assessments of the negotiation process for educational needs of sexual harassed and abused children. Result: The sexual harassment and violence prevention program will contain four subjects : 1) sexual development of a preschool child, 2) characteristics of sexual harassment and violence of a preschool child, 3) safe sex, early detection of sexual violence syndrome, and coping strategies. The CD-RON was composed from three sites. The first was a child site, the second was a parent/teacher site, and the third was a game site for evaluations. The child site consisted of 10 possible scenarios of sexual harassment and violence that a child could experience. The parent/teacher site consisted of knowledge and information for prevention and coping strategies for sexual harassment and violence. At the end of each situation question and answer sections that were used for formative evaluation. Also, the game site could be a summative evaluation. Conclusion: The effects of this program and the CD-ROM were based of the promotion of reverence for humanity and gender equality for preschool childen. Eventually, children, parents, and teachers will have prevention and coping ability that will reduce the occurrence of sexual harassment and violence in Korea

• 한국문헌정보학회지
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• 제27권
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• pp.183-214
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• 1994

The purpose of this study is to suggest the schemes to enhance information service functions by the utilization of CD-ROM in medical school libraries. The results of the study are summarized as follows : 1. The selection and evaluation of CD-ROM database are necessary steps in the planning of a CD-ROM. Before the CD-ROM is selected, therefore, medical libraries must make a practical evaluation criteria in important order of information services environment, characteristics of hardware/software, service requirements, price and cost, etc. 2. If possible, CD-ROM MEDLINE must be suited for the information services environment. 3. In case of the popular core journals, full-text CD-ROM should be gradually purchased. 4. In order to reduce the time required from search of bibliographic informations to receipt of original articles, CD-NET system and library holding administration program must be built up and developed. And channel of information search and order/receipt of original article should be varied. 5. Search education program for medical librarians and users should be enforced, and librarians must play an important role in CD-ROM retrieval consultant and intermediator.

• Journal of Hospice and Palliative Care
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• 제12권2호
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• pp.61-71
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• 2009

목적: 본 연구는 청소년 후기 말기 암 환자의 전반적인 경험을 이해하고 총체적인 고통을 경감하도록 돕는 정서적, 영적 돌봄 프로그램인 CD 프로그램을 개발하기 위한 것이다. 방법: 2006년 11월 1일부터 2007년 10월 30일까지 Keller와 Song의 ARCS이론과 Kang의 멀티미디어 코스웨어 설계 과정을 응용하여 플래쉬 도구를 활용한 CD 프로그램을 개발하였으며, 개발된 의미요법 프로그램명은 "청소년 후기 암 환자를 위한 "내 삶의 보물찾기""이었다. 프로그램 개발은 <계획>, <설계>, <개발>-CD프로그램, 사용자(간호사)용 교육지침서 및 학습자용 교육용 책자, <평가>의 4단계를 통해 이루어졌다. 결과: 본 연구에서 개발된 의미요법 CD 프로그램은 총 5개의 비밀을 찾는 과정으로 교육시간은 각 차시별로 $15{\sim}20$분으로 구성되었으며. "비밀"로 명명된 각 차시별 구성은 의미요법에 대한 프로그램의 제작목적을 알려주는 <처음>과 6컷 만화를 통한 동기유발을 유도하기 위한 <마음열기>, 각 차시별 교육목적과 의미요법 교육이 진행되는 영상물 상영 <알아보기>, 교육 내용에 대한 카타르시스를 위한 <웃음 송>, 교육내용을 자신에게 직접 적용해 보는 <경험하기>, 메인화면으로 돌아갈 수 있는 <끝>의 6단계로 이루어졌으며, 교육용 소책자(의미노트)를 제공하여 반복학습이 이루어질 수 있도록 하였다. 본 프로그램은 청소년 말기 암환자가 있는 임상현장인 병원학교 혹은 지역사회 어느 곳이든지 컴퓨터가 가능한 곳에서는 사용할 수 있도록 CD로 만들어졌으며, 프로그램은 신규 간호사도 사용하기 편리하게 자동과 수동 양방향의 기능을 가지고 매체조작이 용이하도록 제작되었다. 교육지침서는 전체 내용을 손쉽게 파악할 수 있도록 되어 있고, <웃음 송>에 대한 저작권 등록은 완료된 상태로 전국의 소아 청소년 종양병동에서 무료로 사용할 수 있도록 하였다. 결론: 본 프로그램은 간호사들이 교육에 대한 큰 부담없이 의미요법 프로그램을 쉽게 진행할 수 있도록 제작되어 있어 임상에서 청소년 후기 말기 암 환자의 정서적, 영적 간호중재 방법으로 유용하다고 판단된다. 또한 말기 암환자 뿐 아니라 청소년 후기에 만성 및 불치의 질병으로 고통을 받는 대상자에게도 적용할 수 있다고 생각된다.

• Molecules and Cells
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• 제25권4호
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• pp.487-493
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• 2008

HoxB4 has been shown to enhance hematopoietic engraftment by hematopoietic stem cells (HSC) from differentiating mouse embryonic stem cell (mESC) cultures. Here we examined the effect of ectopic expression of HoxB4 in differentiated human embryonic stem cells (hESCs). Stable HoxB4-expressing hESCs were established by lentiviral transduction, and the forced expression of HoxB4 did not affect stem cell features. HoxB4-expressing hESC-derived CD34+ cells generated higher numbers of erythroid and blast-like colonies than controls. The number of CD34+ cells increased but CD45+ and KDR+ cell numbers were not significantly affected. When the hESC derived CD34+ cells were transplanted into $NOD/SCID{\beta}2m-/-$ mice, the ectopic expression of HoxB4 did not alter their repopulating capacity. Our findings show that overexpression of HoxB4 in differentiating hESCs increases hematopoietic colony formation and hematopoietic cell formation in vitro, but does not affect in vivo repopulation in adult mice hosts.