• Title/Summary/Keyword: CC14

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The Screening of Hepatic Functional Improvement. Liver Protection and Antifibrotic Effect from Dried Extracts of Concha Cipangopaludinae

  • Kim, Hee-Seok;Bae, Heung-Mo;Kim, Eun-Sook;Kim, Jin-Sook;Kim, Ki-Young
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.286.2-286.2
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    • 2002
  • Oxidative stress and its consequent lipid peroxidation exert harmful effects, which have been currently involved in the generation of carbon tetrachloride(CC14)-induced fibrosis(cirrhosis). In this study, it was investigated whether dried extract of 田螺(Concha Cipangopaludinae: CC) is liver functional improvement, antioxidative and antifibrotic effect under the liver fibrotic(cirrhotic) condition by CC14 administration. The female Sprague-Dawley rats were divided into 3 groups(Normal, AC, AC-CC), and were observed for 3 weeks. (omitted)

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어도비 포토샵 CC 신기능 리뷰어 - 원근 뒤틀기(Perspective Warp)

  • 대한인쇄문화협회
    • 프린팅코리아
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    • v.14 no.4
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    • pp.92-95
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    • 2014
  • 최근 출시된 어도비 포토샵 CC에는 이전에 없던 다양한 신기능이 많이 포함돼 있다. 원근 뒤틀기(Perspective Warp)도 그중의 하나다. 원근 뒤틀기는 이미지에서 서로 다른 원근의 소실점을 정렬해 하나의 완벽한 합성 사진을 만드는 기능이다. 원근 뒤틀기에 대해 알아본다.

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TGF-β-activated Kinase-1: A Potential Prognostic Marker for Clear Cell Renal Cell Carcinoma

  • Wei, Can;Lai, Yong-Qing;Li, Xian-Xin;Ye, Jiong-Xian
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.315-320
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    • 2013
  • Background: TGF-${\beta}$-activated kinase-1 (TAK1) has been found to be over-expressed in a variety of solid malignancies and related to tumor growth. The aim of this study was to evaluate the expression level of TAK1 in clear cell renal cell carcinoma (ccRCC) and assess its value as a novel prognostic marker. Methods: TAK1 mRNA was assessed in 51 paired ccRCC tissues and adjacent normal tissues (ADTs) by real-time PCR. Tissue TAK1 protein was also assessed in 91 ADTs and 177 samples of ccRCC immunohistochemically for evaluation of relationships with clinical characteristics. Results: RT-PCR showed that TAK1 RNA level was significantly higher in ccRCC tissues than in the paired ADTs and immunohistochemistry confirmed higher expression of TAK1 protein in ccRCC samples compared with ADTs. TAK1 protein expression in 177 ccRCC samples was significantly correlated with T stage, N classification, metastasis, recurrence and Fuhrman grade, but not age and gender. Patients with low TAK1 levels had a better survival outcome. TAK1 expression and N stage were independent prognosis factors for the overall survival of ccRCC patients. Conclusions: Overexpression of TAK1 predicts a poor prognosis in patients with ccRCC, so that TAK1 may serve as a novel prognostic marker.

Ship Repair Workers' Exposure to Asbestos by a Systematic Review in Korea (문헌 조사를 통한 국내 선박 수리 작업자들의 석면 노출 특성 분석)

  • Choi, Sang-Jun;Kwon, Hyo-Jung;Gwak, Su-Gyeong
    • Journal of the Korea Safety Management & Science
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    • v.14 no.3
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    • pp.135-141
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    • 2012
  • This study was conducted to evaluate the characteristics of exposure to asbestos for ship repair workers in Korea by a systematic review. The number of articles studying asbestos exposure levels from ship repair workplaces was found to be 4. All asbestos concentration reported as either geometric mean and geometric standard deviation or ranges were transformed to arithmetic mean to estimate exposure level. In addition, weighted arithmetic means(WAMs) were calculated by weighing of the different number of samples. The WAM concentrations were 2.746 f/cc during asbestos dismantling work, 0.034 f/cc before asbestos dismantling work and 0.065 f/cc after working respectively. The maximum airborne concentration of asbestos during asbestos removal work was 7.02 f/cc which was 70 times higher than the occupational exposure limit of Korea, 0.1 f/cc. This study recommends that retrospective exposure to asbestos based on various ship types and operations should be assessed.

Effect of Cooling Water Capacity on the Engine Performance for Small Diesel Engine (냉각수(冷却水) 용량(容量)이 소형(小型) 디젤기관(機關)의 성능(性能)에 미치는 영향(影響))

  • Myung, Byung Soo;Kim, Soung Rai
    • Korean Journal of Agricultural Science
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    • v.13 no.2
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    • pp.265-278
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    • 1986
  • This study was attempted to improve the thermal efficiency of 6 kW water-cooled diesel engine on power tiller. The engine performance tests were conducted to find out the effect of cooling water capacity of 2700cc, 2800cc, 2900cc, 3000cc, 3100cc on power, brake specific fuel consumption (BSFC), torque, temperature of cooling water and lubricating oil and friction losses of the engine with D. C. dynamometer. The results obtained in the study are summarized as follows: 1. The performance of the engine tested was adequated to Korea Industrial Standard but actual economy power was 10% higher than the labeled rated power of the engine. The BSFC of the engine tested 297.8g/kW-h which is belong a little higher level than hreign products. The temperature of cooling water was $101^{\circ}C$ which is higher than SAE standard ($88^{\circ}C$) 2. The friction losses of engine tested was 3.656 kW at 2200 rpm of rated rpm (piston speed 6.97m/sec) and is higher than those of foreign products. 3. When the cooling water capacity was increased from 2700cc to 3100cc the power output of the engine was increased from 6.7 kW to 7.13 kW at the rate of 6.4% and also the torque of the engine was increased from 28.85 N.m to 30.76 N.m at the rate of 6.39%. 4. When the cooling water capacity was increased from 2700cc to 3100cc, the BSFC was decreased 6.9g/kW-h from 310.9g/kW-h to 304.1g/kW-h, and after one half hour operation with full load, the temperature of cooling water was decreased $13^{\circ}C$ from $101^{\circ}C$ to $88^{\circ}C$ and also the temperature of lubricant oil was decreased $6.4^{\circ}C$ from $76.7^{\circ}C$ to $70.4^{\circ}C$. 5. The mechanical efficiency was increased from 70.08% to 71.08% when the cooling water capacity was increased from 2700cc to 3100cc.

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High Mobility Group Box 1 Protein Is Methylated and Transported to Cytoplasm in Clear Cell Renal Cell Carcinoma

  • Wu, Fei;Zhao, Zuo-Hui;Ding, Sen-Tai;Wu, Hai-Hu;Lu, Jia-Ju
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5789-5795
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    • 2013
  • Background: The high mobility group box 1 (HMGB1) protein is a widespread nuclear protein present in most cell types. It typically locates in the nucleus and functions as a nuclear cofactor in transcription regulation. However, HMGB1 can also localize in the cytoplasm and be released into extracellular matrix, where it plays critical roles in carcinogenesis and inflammation. However, it remains elusive whether HMGB1 is relocated to cytoplasm in clear cell renal cell carcinoma (ccRCC). Methods: Nuclear and cytoplasmic proteins were extracted by different protocols from 20 ccRCC samples and corresponding adjacent renal tissues. Western blotting and immunohistochemistry were used to identify the expression of HMGB1 in ccRCC. To elucidate the potential mechanism of HMGB1 cytoplasmic translocation, HMGB1 proteins were enriched by immunoprecipitation and analyzed by mass spectrometry (MS). Results: The HMGB1 protein was overexpressed and partially localized in cytoplasm in ccRCC samples (12/20, 60%, p<0.05). Immunohistochemistry results indicated that ccRCC of high nuclear grade possess more HMGB1 relocation than those with low grade (p<0.05). Methylation of HMGB1 at lysine 112 in ccRCC was detected by MS. Bioinformatics analysis showed that post-translational modification might affect the binding ability to DNA and mediate its translocation. Conclusion: Relocation of HMGB1 to cytoplasm was confirmed in ccRCC. Methylation of HMGB1 at lysine 112 might the redistribution of this cofactor protein.

CC-GiST: A Generalized Framework for Efficiently Implementing Arbitrary Cache-Conscious Search Trees (CC-GiST: 임의의 캐시 인식 검색 트리를 효율적으로 구현하기 위한 일반화된 프레임워크)

  • Loh, Woong-Kee;Kim, Won-Sik;Han, Wook-Shin
    • The KIPS Transactions:PartD
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    • v.14D no.1 s.111
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    • pp.21-34
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    • 2007
  • According to recent rapid price drop and capacity growth of main memory, the number of applications on main memory databases is dramatically increasing. Cache miss, which means a phenomenon that the data required by CPU is not resident in cache and is accessed from main memory, is one of the major causes of performance degradation of main memory databases. Several cache-conscious trees have been proposed for reducing cache miss and making the most use of cache in main memory databases. Since each cache-conscious tree has its own unique features, more than one cache-conscious tree can be used in a single application depending on the application's requirement. Moreover, if there is no existing cache-conscious tree that satisfies the application's requirement, we should implement a new cache-conscious tree only for the application's sake. In this paper, we propose the cache-conscious generalized search tree (CC-GiST). The CC-GiST is an extension of the disk-based generalized search tree (GiST) [HNP95] to be tache-conscious, and provides the entire common features and algorithms in the existing cache-conscious trees including pointer compression and key compression techniques. For implementing a cache-conscious tree based on the CC-GiST proposed in this paper, one should implement only a few functions specific to the cache-conscious tree. We show how to implement the most representative cache-conscious trees such as the CSB+-tree, the pkB-tree, and the CR-tree based on the CC-GiST. The CC-GiST eliminates the troublesomeness caused by managing mire than one cache-conscious tree in an application, and provides a framework for efficiently implementing arbitrary cache-conscious trees with new features.

Single mode yield analysis of complex-coupled DFB lasers above threshold for various coupling coefficient ratios and facet reflectivity combinations (문턱 전류 이상에서 Complex-Coupled DFB 레이저 다이오드의 여러 가지 결합 계수 비와 양 단면 반사율 조합에 따른 단일 모드 수율 해석)

  • 김부균;김상택;전재두
    • Korean Journal of Optics and Photonics
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    • v.14 no.5
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    • pp.521-529
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    • 2003
  • For complex-coupled (CC) DFB lasers, we found that there might be little correlation between the single mode yields at threshold and above threshold. At threshold, the single mode yield considering f number of in-phase (IP) CC DFB lasers is the same as that of anti-phase (AP) CC DFB lasers. However, the single mode yield as a function of injection current above threshold of IP CC DFB lasers is much different from that of AP CC DFB lasers. In the case of IP CC DFB lasers, the single mode yield increases as the coupling coefficient ratio (CR) increases, while, in the case of AP CC DFB lasers, the single mode yield decreases rapidly regardless of CR as the injection current increases. In the case of AR-HR combinations, the effect of AR ref1ectivity on the single mode yield increases as the coupling strength decreases. As the coupling strength decreases, the CR at which the increase rate of the single mode yield starts to decrease, increases, and the maximum single mode yield increases. Single mode yields of AR-HR and AR-AR combinations are larger than those of AR-CL and CL-CL combinations.

국제 공통평가기준(CC) 체제하에 평가된 정보보호 제품 분석

  • 오흥룡;염흥열
    • Review of KIISC
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    • v.14 no.4
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    • pp.54-67
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    • 2004
  • IT(Information Technology) 제품의 보안 기능을 평가하기 위하여 서로 다른 체계를 이용할 경우 평가를 위한 이중의 비용 소요와 추가의 시간 소모 등의 문제점을 해결하기 위하여, 미국, 영국, 호주 등의 선진국들은 국제 간에 상호 인정이 가능한 공통평가기준(CC: Common Criteria)에 대한 연구가 활발히 진행되고 있다. 현재 우리나라도 국제상호인정협정(CCRA)에 가입을 준비중에 있으며, 다양한 IT 제품으로 평가 제도의 확대를 준비하고 있다. 본 논문에서는 미국, 영국, 호주의 CC 체제 하에서 평가된 정보보호 제품들의 특성을 분석하고, 이를 근거로 우리나라 IT 제품의 보안기능 평가에 적용 가능한 분류 체계를 고찰해 본다.

어도비 CC 2014 신기능 1> 추가된 새로운 모션 효과

  • 대한인쇄문화협회
    • 프린팅코리아
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    • v.13 no.8
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    • pp.114-116
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    • 2014
  • 어도비는 최근 크리에이티브 클라우드의 14개 데스크톱 애플리케이션의 새 버전을 발표했다. 이번 대규모 업데이트는 CS6 이래 가장 큰 규모로, 4가지 새로운 모바일 앱 및 크리에이티브 클라우드 서비스의 업데이트가 포함돼 있다. 포토샵 CC에는 더욱 똑똑해진 스마트 가이드, 향상된 레이어 구성요소, 사실적인 모션 블러 효과 등이 추가됐다. 추가된 새로운 모션 효과에 대해 알아본다.

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