• 한국초전도ㆍ저온공학회논문지
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• 제24권1호
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• pp.13-17
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• 2022

The mechanical properties of REBCO coated conductor (CC) tapes under uniaxial tension are mainly determined by the thick layer Components like the substrate and the stabilizer. Depending on the applications of the CC tapes, it is also needed to externally reinforce thin metallic foils to one side or both sides of the CC tapes. This study investigated the effect of additional stabilizer layers or lamination on the electrical resistivity and electromechanical properties in RCE-DR processed GdBCO CC tapes with different structures. The strain/stress tolerance of I_c in differently processed 12 mm-wide REBCO CC tapes under uniaxial tension at 77 K and self-field could be determined by the loading-unloading scheme. As a result, Sn-Cu stabilized CC tape showed a significant decrease in mechanical properties due to its soft but thick stabilizing layer. However, similar electromechanical properties have been observed on both Sn-Cu and Sn-stabilized CC tapes, the I_c degradation behavior was independent of whether the CC tape has an external reinforcement or different stabilizing layers.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.109.1-109
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• 2003

From the PMMV (pepper mild mottle virus)-inducible ESTs differentially expressed in Capsicum chinense PI257284, we isolated a full-length cDNA (CcPHZF： Capsicum chinense phenazine), encoding a phenazine biosynthesis protein which catalyzes the hydroxylation of phenozine-1-carboxylic acid to 2-hydroxyphenazine-1-carboxylic acid. Phenazine compound has been known to exhibit broad-spectrum of antibiotic activity against various species of bacteria and fungus. The entire region of CcPHZF is 879 bp in length and the open reading frame predicted a polypeptide of 292 amino acids. The homolog of CcPHZF is not Present in database except clones of AC004044 and NM100203 from Arabidopsis with 58 and 59％, respectively. Genomic Southern analysis indicated that the pepper genome contains a single copy of CcPHZF. The CcPHZF was strongly induced in the pepper leaves 3 days after PMMV treatment, when HR occurs on the leaf surface. Characterization of CcPHZF is underway to investigate if the CcPHZF is related to disease resistance against pathogens.

• Mycobiology
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• 제46권1호
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• pp.24-32
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• 2018

Improper disposal of herb residues in China has caused severe problems to the surrounding environment and human safety. Three herb residues, i.e., compound Kushen injection residues (CKI) and part one and part two of Qizhitongluo Capsule residues (QC1 and QC2, respectively), were used for the cultivation of Pleurotus ostreatus. The effect of the supplementation of corncobs (CC) with different herb residues on yield, nutritional composition, and antioxidant activity of P. ostreatus was investigated. Compared to the control, the higher mycelial growth rate was observed on substrates CC +30% CKI and CC +30% QC1, while the higher yield was obtained from substrates CC +30% QC2 and CC +30% CKI. Moreover, chemical analysis of fruit bodies revealed that the addition of herb residues to CC significantly increased proteins, amino acids, ashes, minerals (Na and Ca), and total phenolic contents but significantly reduced carbohydrates and $IC_{50}$ values of DPPH radicals. In addition, no heavy metals (Pb, Cd, and As) were detected in the fruiting bodies harvested from different substrate combinations. These results demonstrated that mixtures of CC with herb residues might be utilized as a novel, practical, and easily available substrate for the cultivation of P. ostreatus, which is beneficial for the effective management of herb residues.

• 한국초전도ㆍ저온공학회논문지
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• 제18권4호
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• pp.21-24
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• 2016

The mechanical properties of REBCO coated conductor (CC) wires under uniaxial tension are largely determined by the thick component layers in the architecture, namely, the substrate and the stabilizer or even the reinforcement layer. Depending on device applications of the CC tapes, it is necessary to reinforce thin metallic foils externally to one-side or both sides of the CC tapes. Due to the external reinforcement of brass foils, it was found that this could increase the reversible strain limit from the Cu-stabilized CC tapes. In this study, the effects of differently hardened brass foil laminate on the electromechanical property of CC tapes were investigated under uniaxial tension loading. The tensile strain dependence of the critical current ($I_c$) was measured at 77 K and self-field. Depending on whether the $I_c$ of CC tapes were measured during loading or after unloading, a reversible strain (or stress) limit could be determined, respectively. The both-sides of the Cu-stabilized CC tapes were laminated with brass foils with different hardness, namely 1/4H, 1H and EH. From the obtained results, it showed that the yield strength of the brass laminated CC tapes with EH brass foil laminate was comparable to the one of the Cu-stabilized CC tape due to its large yield strength even though its large volume fraction. It was found that the brass foil with different hardness was mainly sensitive on the stress dependence of $I_c$, but not on the strain sensitivity due to the residual strain induced in the laminated CC tapes during unloading.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.5789-5795
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• 2013

Background: The high mobility group box 1 (HMGB1) protein is a widespread nuclear protein present in most cell types. It typically locates in the nucleus and functions as a nuclear cofactor in transcription regulation. However, HMGB1 can also localize in the cytoplasm and be released into extracellular matrix, where it plays critical roles in carcinogenesis and inflammation. However, it remains elusive whether HMGB1 is relocated to cytoplasm in clear cell renal cell carcinoma (ccRCC). Methods: Nuclear and cytoplasmic proteins were extracted by different protocols from 20 ccRCC samples and corresponding adjacent renal tissues. Western blotting and immunohistochemistry were used to identify the expression of HMGB1 in ccRCC. To elucidate the potential mechanism of HMGB1 cytoplasmic translocation, HMGB1 proteins were enriched by immunoprecipitation and analyzed by mass spectrometry (MS). Results: The HMGB1 protein was overexpressed and partially localized in cytoplasm in ccRCC samples (12/20, 60%, p<0.05). Immunohistochemistry results indicated that ccRCC of high nuclear grade possess more HMGB1 relocation than those with low grade (p<0.05). Methylation of HMGB1 at lysine 112 in ccRCC was detected by MS. Bioinformatics analysis showed that post-translational modification might affect the binding ability to DNA and mediate its translocation. Conclusion: Relocation of HMGB1 to cytoplasm was confirmed in ccRCC. Methylation of HMGB1 at lysine 112 might the redistribution of this cofactor protein.

• 동아시아식생활학회지
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• 제15권4호
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• pp.437-443
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• 2005

Quality characteristic of Kipfel cookies with 0, 20, 40 and $60\%$ of freeze dried chitosan-chungkukjang(CC), which was fermented for 24 hours at $40^{\circ}C$ with steamed soybean added with $0.25\%$ of chitosan(MW 2,025 kDa) powder and inoculated $2\%$ of Bacillus lichenifomis, were investigated Bulk density was higher in the CC cookie, but there were no difference among the CC cookies. While hardness was decreased, brittleness and springiness were increased in the higher ratio of CC, but no significant difference was observed in cohesiveness and gumminess. According to increasing the CC ratio, L$\ast$ values and hue angle were decreased from 62.69 and 96.71 to 44.41 and 69.30, respectively. While a$\ast$ values were increased from -1.94 to 4.95, and no changes were observed in b$\ast$ values. Glucosamine content was $27.34 mg\%$ in the control cookie, $40{\~}93.75 mg\%$ in the CC cookies. Antioxidant activity of the CC cookies were higher than the control. The activity of the control cookie was decreased during storage, while it was maintained in CC cookies. There were no differences in the sour, sweet and savory taste. Off-flavor did not detected in the $0{\~}40\%$ CC cookies, but the chungkukjang odor was slightly detected in the $60\%$ CC cookie. The $20{\~}40\%$ CC cookies did not affect on native odor of Kipfel cookie. Color acceptability also did not affect by addition of CC $20{\~}40\%$ but it was lower in $60\%$ CC cookie. Overall acceptability was the best in the $20\%$ CC cookie.

• 한국융합학회논문지
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• 제2권1호
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• pp.31-36
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• 2011

이 연구는 치과 기공사의 석면 사용의 문제를 조사 수행하였다. 분석을 위한 샘플은 2010년 12월에서, 2011년 1월까지 대구광역시 10개 치과기공소에서 40개의 샘플링을 개인 샘플러에 의해 샘플 되었고 위상차 현미경으로 분석하였다. 측정결과는 다음과 같다. 1. 10개 치과기공소 40개소의 공기 중 석면의 기하평균농도는 0.0061 f/cc 로서 작업환경기준 및 실내환경기준에 미달하였으나 2개 치과기공소에서 실내환경관리기준을 초과하였다. 2. 가공실과 소환실의 공기 중 석면의 기하평균농도는 가공실이 0.0099 f/cc로 소환실 0.0037 f/cc 보다 높았다. 3. 치과기공소에서 사용 중인 Casting ring liner 종류별 공기 중 석면농도는 산업용석면제품을 사용하는 곳이 0.0159f/cc로 가장 높았고, 다음이 석면함유제품을 사용하는 곳 0.0104 f/cc, 비석면제품을 사용하는 곳 0.0026 f/cc 순으로 나타났다. 치과기공소에서 석면이 함유된 Casting ring liner를 사용하고 작업환경농도 또한 일부 치과기공소에서 실내환경기준을 초과하는 것으로 나타나고 있으므로 석면제품 Casting ring liner를 비석면제품으로 대치(Substitution)하는 대책이 시급히 강구되어야 하고 환기설비를 보완하여 치과기공사들의 건강을 보호할 수 있도록 하여야 하겠다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5259-5264
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• 2014

Background: CT based brachytherapy allows 3-dimensional (3D) assessment of organs at risk (OAR) doses with dose volume histograms (DVHs). The purpose of this study was to compare computed tomography (CT) based volumetric calculations and International Commission on Radiation Units and Measurements (ICRU) reference-point estimates of radiation doses to the bladder and rectum in patients with carcinoma of the cervix treated with high-dose-rate (HDR) intracavitary brachytherapy (ICBT). Materials and Methods: Between March 2011 and May 2012, 20 patients were treated with 55 fractions of brachytherapy using tandem and ovoids and underwent post-implant CT scans. The external beam radiotherapy (EBRT) dose was 48.6Gy in 27 fractions. HDR brachytherapy was delivered to a dose of 21 Gy in three fractions. The ICRU bladder and rectum point doses along with 4 additional rectal points were recorded. The maximum dose ($D_{Max}$) to rectum was the highest recorded dose at one of these five points. Using the HDRplus 2.6 brachyhtherapy treatment planning system, the bladder and rectum were retrospectively contoured on the 55 CT datasets. The DVHs for rectum and bladder were calculated and the minimum doses to the highest irradiated 2cc area of rectum and bladder were recorded ($D_{2cc}$) for all individual fractions. The mean $D_{2cc}$ of rectum was compared to the means of ICRU rectal point and rectal $D_{Max}$ using the Student's t-test. The mean $D_{2cc}$ of bladder was compared with the mean ICRU bladder point using the same statistical test. The total dose, combining EBRT and HDR brachytherapy, were biologically normalized to the conventional 2 Gy/fraction using the linear-quadratic model. (${\alpha}/{\beta}$ value of 10 Gy for target, 3 Gy for organs at risk). Results: The total prescribed dose was $77.5Gy{\alpha}/{\beta}10$. The mean dose to the rectum was $4.58{\pm}1.22Gy$ for $D_{2cc}$, $3.76{\pm}0.65Gy$ at $D_{ICRU}$ and $4.75{\pm}1.01Gy$ at $D_{Max}$. The mean rectal $D_{2cc}$ dose differed significantly from the mean dose calculated at the ICRU reference point (p<0.005); the mean difference was 0.82 Gy (0.48-1.19Gy). The mean EQD2 was $68.52{\pm}7.24Gy_{{\alpha}/{\beta}3}$ for $D_{2cc}$, $61.71{\pm}2.77Gy_{{\alpha}/{\beta}3}$ at $D_{ICRU}$ and $69.24{\pm}6.02Gy_{{\alpha}/{\beta}3}$ at $D_{Max}$. The mean ratio of $D_{2cc}$ rectum to $D_{ICRU}$ rectum was 1.25 and the mean ratio of $D_{2cc}$ rectum to $D_{Max}$ rectum was 0.98 for all individual fractions. The mean dose to the bladder was $6.00{\pm}1.90Gy$ for $D_{2cc}$ and $5.10{\pm}2.03Gy$ at $D_{ICRU}$. However, the mean $D_{2cc}$ dose did not differ significantly from the mean dose calculated at the ICRU reference point (p=0.307); the mean difference was 0.90 Gy (0.49-1.25Gy). The mean EQD2 was $81.85{\pm}13.03Gy_{{\alpha}/{\beta}3}$ for $D_{2cc}$ and $74.11{\pm}19.39Gy_{{\alpha}/{\beta}3}$ at $D_{ICRU}$. The mean ratio of $D_{2cc}$ bladder to $D_{ICRU}$ bladder was 1.24. In the majority of applications, the maximum dose point was not the ICRU point. On average, the rectum received 77% and bladder received 92% of the prescribed dose. Conclusions: OARs doses assessed by DVH criteria were higher than ICRU point doses. Our data suggest that the estimated dose to the ICRU bladder point may be a reasonable surrogate for the $D_{2cc}$ and rectal $D_{Max}$ for $D_{2cc}$. However, the dose to the ICRU rectal point does not appear to be a reasonable surrogate for the $D_{2cc}$.

• 정보처리학회논문지A
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• 제11A권3호
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• pp.199-206
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• 2004

다중 프로세서 시스템에서 여러 개의 프로그램이 동시에 수행될 경우의 프로그램 수행 성능은 각 프로세스를 어떠한 물리적 위치의 프로세서에 할당하여 수행하는가에 따라 다르게 나타난다. 일반적으로 시공간적으로 인접한 프로세서에 동일 프로그램의 프로세서를 할당할 경우 프로세스간 통신비용이 절감되므로 가장 효율적인 결과를 얻을 수 있다. 그러나 프로세스를 할당하는 운영체제는 이와 같은 친화성을 고려하기 위하여 부가적인 처리를 필요로 하며, 실제 수행시 각 프로그램은 독립적으로 수행되므로, 여러 프로그램으로부터 발생한 프로세스를 할당하는 방법은 많은 계산을 필요로 한다. 이중 링 구조의 CC-NUMA 시스템의 경우 특히 다수의 공유 메모리 접근에 의한 많은 트랜잭션이 발생하며, 연결망 부하의 불균등에 따른 병목 현상을 나타내므로, 프로세스의 할당 정책에 따라서 큰 성능 차이를 나타내게 된다. 본 논문은 규일한 연결망 부하특성을 나타내며, 프로세스 할당 정책을 필요로 하지 않는 CC-NUMA 시스템을 제시한다. 논문에서 제시하는 구조는 이중 링 구조와 동일한 연결망 비용을 나타내며, 건너뜀 연결을 이용한 균등한 부하 분배를 수행함으로써 프로세스 할당 정책의 유무와 무관한 성능을 보이다. 프로그램 구동 시뮬레이션을 통한 검증 결과 시스템은 이중 링 구조의 CC-NUMA 시스템에 비하여 1.5배의 성능 개선을 나타냈다.

• 한국산업보건학회지
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• 제23권2호
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• pp.123-136
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• 2013

Objectives: This paper was prepapred to report airborne asbestos fiber concentrations in asbestos textile, brake-lining, commutator, and building materials manufacturing industries, and some other asbestos related industries in Korea from 1994 to 2006. Methods: Airborne asbestos data that have been sampled and analyzed in the above industries during 1994-2006 were collected. These data were reviewed to scrutinize the qualified data based on the records such as sampling and analyzed method and quality control procedures. All asbestos data were generated using the National Institute for Occupational Safety & Health (NIOSH) Method 7400. Results: Average concentration of asbestos fiber was 2.14 fibers/cc(0.02-15.6 fibers/cc) in the asbestos textile industry, 0.26 fibers/cc(0.01-1.01 fibers/cc) in the building-materials industry, 0.15 fibers/cc(0.01-0.93 fibers/cc) in the brake-lining manufacturing industry, and 0.14 fibers/cc(0.03-1.36 fibers/cc) in the commutator producing industry. For these industries, the percentage of samples of which asbestos fiber concentrations above the limit of exposure(0.1 fibers/cc) was 97.6% in the asbestos textile industry, 62.3% in the building-materials industry, 53.5% in the brake-lining manufacturing industry, and 34.3% in the commutator producing industry. Asbestos fiber concentration was below the limit of exposure in the gasket producing, petrochemistry, musical instrument producing industries, and the brake-lining exchange operations. Conclusions: Airborne asbestos fiber level in the asbestos textile, brake-lining producing, commutator and building-material producing industries was above the limit of exposure, but in the gasket producing, petrochemistry, musical instrument producing industries and the brake-lining exchange operations were below the limit of exposure.